Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Show chains
Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
2HVY_A
|
2HVY_E
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:58 [PRO] | E:19 [C] | 4.67 | E:39 [G] | 52.64 | ||
A:59 [GLY] | E:17 [C] | 4.2 | E:41 [G] | 93.04 | ||
A:59 [GLY] | E:18 [C] | 3.39 | E:40 [G] | 93.04 | ||
A:59 [GLY] | E:19 [C] | 4.73 | E:39 [G] | 93.04 | ||
A:60 [PRO] | E:18 [C] | 3.71 | E:40 [G] | 62.66 | ||
A:60 [PRO] | E:19 [C] | 4.9 | E:39 [G] | 62.66 | ||
A:61 [THR] | E:42 [U] | 4.22 | E:16 [G] | 90.9 | ||
A:63 [HIS] | E:42 [U] | 3.2 | E:16 [G] | 72.1 | ||
A:63 [HIS] | E:43 [A] | 2.78 | 72.1 | |||
A:63 [HIS] | E:44 [A] | 4.79 | 72.1 | |||
A:63 [HIS] | E:45 [U] | 3.91 | 72.1 | |||
A:64 [GLU] | E:17 [C] | 4.51 | E:41 [G] | 67.01 | ||
A:64 [GLU] | E:18 [C] | 3.79 | E:40 [G] | 67.01 | ||
A:64 [GLU] | E:41 [G] | 2.6 | E:17 [C] | base:SC | 67.01 | |
A:64 [GLU] | E:42 [U] | 3.72 | E:16 [G] | 67.01 | ||
A:67 [ALA] | E:42 [U] | 3.99 | E:16 [G] | 51.59 | ||
A:68 [TRP] | E:18 [C] | 3.84 | E:40 [G] | 48.19 | ||
A:68 [TRP] | E:19 [C] | 4.19 | E:39 [G] | 48.19 | ||
A:68 [TRP] | E:41 [G] | 4.56 | E:17 [C] | 48.19 | ||
A:79 [GLY] | E:45 [U] | 3.73 | 94.53 | |||
A:80 [HIS] | E:45 [U] | 2.71 | base:BB, base:BB | base/AA stacks | 96.73 | |
A:81 [GLY] | E:45 [U] | 4.65 | 62.0 | |||
A:82 [GLY] | E:45 [U] | 3.47 | base:BB | 97.83 | ||
A:83 [THR] | E:45 [U] | 3.76 | 98.72 | |||
A:86 [PRO] | E:17 [C] | 4.8 | E:41 [G] | 97.53 | ||
A:101 [ARG] | E:5 [C] | 2.67 | E:53 [G] | 83.36 | ||
A:101 [ARG] | E:6 [C] | 3.99 | E:52 [G] | 83.36 | ||
A:103 [VAL] | E:45 [U] | 4.39 | 66.34 | |||
A:107 [LEU] | E:45 [U] | 3.25 | 4.36 | |||
A:259 [LYS] | E:60 [A] | 4.07 | 60.33 | |||
A:259 [LYS] | E:61 [G] | 2.88 | 60.33 | |||
A:261 [SER] | E:60 [A] | 2.68 | sugar:SC | 57.62 | ||
A:261 [SER] | E:61 [G] | 3.03 | 57.62 | |||
A:262 [ALA] | E:60 [A] | 3.49 | 48.37 | |||
A:265 [ALA] | E:58 [A] | 3.59 | 57.45 | |||
A:265 [ALA] | E:60 [A] | 3.33 | 57.45 | |||
A:266 [VAL] | E:4 [U] | 4.82 | E:54 [A] | 67.62 | ||
A:266 [VAL] | E:60 [A] | 4.77 | 67.62 | |||
A:267 [THR] | E:4 [U] | 3.69 | E:54 [A] | 51.85 | ||
A:268 [HIS] | E:3 [G] | 2.65 | E:55 [C] | base:BB | 71.63 | |
A:268 [HIS] | E:4 [U] | 4.58 | E:54 [A] | 71.63 | ||
A:268 [HIS] | E:55 [C] | 3.22 | E:3 [G] | sugar:SC | 71.63 | |
A:268 [HIS] | E:56 [C] | 3.66 | E:2 [G] | sugar:SC | 71.63 | |
A:268 [HIS] | E:58 [A] | 2.86 | base:BB | 71.63 | ||
A:269 [GLY] | E:3 [G] | 2.53 | E:55 [C] | sugar:BB | 98.5 | |
A:269 [GLY] | E:4 [U] | 3.27 | E:54 [A] | 98.5 | ||
A:269 [GLY] | E:58 [A] | 3.32 | 98.5 | |||
A:270 [ALA] | E:3 [G] | 4.66 | E:55 [C] | 56.28 | ||
A:270 [ALA] | E:58 [A] | 3.4 | 56.28 | |||
A:270 [ALA] | E:60 [A] | 3.62 | 56.28 | |||
A:271 [ASP] | E:60 [A] | 3.18 | base:BB | 41.58 | ||
A:272 [LEU] | E:60 [A] | 3.98 | 65.48 | |||
A:273 [ALA] | E:59 [C] | 3.43 | 7.43 | |||
A:273 [ALA] | E:60 [A] | 3.01 | base:BB | 7.43 | ||
A:274 [VAL] | E:59 [C] | 4.78 | 2.66 | |||
A:274 [VAL] | E:60 [A] | 4.92 | 2.66 | |||
A:275 [PRO] | E:59 [C] | 3.64 | 41.04 | |||
A:275 [PRO] | E:60 [A] | 3.65 | 41.04 | |||
A:275 [PRO] | E:61 [G] | 4.08 | 41.04 | |||
A:276 [GLY] | E:60 [A] | 3.39 | 42.42 | |||
A:316 [THR] | E:59 [C] | 4.66 | 32.34 | |||
A:317 [LYS] | E:59 [C] | 3.41 | 18.39 | |||
A:318 [GLY] | E:59 [C] | 2.87 | base:BB | 67.06 | ||
A:319 [ILE] | E:59 [C] | 3.61 | 2.27 | |||
A:323 [VAL] | E:3 [G] | 4.72 | E:55 [C] | 52.91 | ||
A:323 [VAL] | E:4 [U] | 3.8 | E:54 [A] | 52.91 | ||
A:324 [GLU] | E:4 [U] | 4.03 | E:54 [A] | 27.57 | ||
A:324 [GLU] | E:5 [C] | 4.16 | E:53 [G] | 27.57 | ||
A:325 [LYS] | E:4 [U] | 4.67 | E:54 [A] | 70.05 | ||
A:325 [LYS] | E:5 [C] | 3.41 | E:53 [G] | 70.05 | ||
A:326 [VAL] | E:4 [U] | 3.49 | E:54 [A] | 87.16 | ||
A:326 [VAL] | E:5 [C] | 2.88 | E:53 [G] | 87.16 | ||
A:330 [ARG] | E:3 [G] | 4.12 | E:55 [C] | 5.58 | ||
A:330 [ARG] | E:4 [U] | 2.47 | E:54 [A] | base:SC | 5.58 | |
A:330 [ARG] | E:5 [C] | 3.34 | E:53 [G] | sugar:SC | 5.58 | |
A:330 [ARG] | E:54 [A] | 4.13 | E:4 [U] | 5.58 | ||
A:330 [ARG] | E:55 [C] | 3.05 | E:3 [G] | base:SC | 5.58 | |
A:335 [LYS] | E:55 [C] | 4.05 | E:3 [G] | 55.29 | ||
A:335 [LYS] | E:56 [C] | 2.54 | E:2 [G] | 55.29 | ||
A:337 [TRP] | E:56 [C] | 3.17 | E:2 [G] | 50.28 | ||
A:337 [TRP] | E:57 [C] | 2.75 | E:1 [G] | 50.28 | ||
A:337 [TRP] | E:58 [A] | 3.42 | 50.28 | |||
A:337 [TRP] | E:59 [C] | 4.05 | 50.28 | |||
A:337 [TRP] | E:60 [A] | 3.86 | 50.28 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group107 | 2HVY_A_E | A: Probable tRNA pseudouridine synthase b, Pyrococcus furiosus (genetically engineered) E: H/aca RNA | Q7LWY0 | PUA domain & Pseudouridine synthase | ✘ |
Interologs
Total number of interologs for this interface: 3
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
2HVY_A_E | 3LWR_A_D,E | 0.78 | 0.94 | 0.97 | 0.5 | PUA domain & Pseudouridine synthase | compare | |
2HVY_A_E | 3HJW_A_D,E | 0.77 | 0.93 | 1.3 | 0.5 | PUA domain & Pseudouridine synthase | compare | |
2HVY_A_E | 3HAX_A_E,F | 0.79 | 0.95 | 0.92 | 0.85 | PUA domain & Pseudouridine synthase | compare |