Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
3LWR_A
|
3LWR_D,E
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:59 [GLY] | D:17 [G] | 4.69 | D:39 [U] | 93.95 | ||
A:59 [GLY] | D:18 [C] | 3.55 | D:38 [G] | 93.95 | ||
A:60 [PRO] | D:18 [C] | 3.65 | D:38 [G] | 67.64 | ||
A:61 [THR] | D:17 [G] | 4.87 | D:39 [U] | 92.71 | ||
A:61 [THR] | D:40 [U] | 3.53 | D:16 [C] | 92.71 | ||
A:61 [THR] | E:69 [G] | 4.54 | 92.71 | |||
A:63 [HIS] | D:40 [U] | 3.32 | D:16 [C] | sugar:SC | 74.63 | |
A:63 [HIS] | D:41 [C] | 3.17 | E:67 [G] | base/AA stacks | 74.63 | |
A:63 [HIS] | E:67 [G] | 4.1 | D:41 [C] | 74.63 | ||
A:63 [HIS] | E:69 [G] | 2.86 | 74.63 | |||
A:63 [HIS] | E:70 [C] | 2.75 | D:15 [G] | 74.63 | ||
A:64 [GLU] | D:17 [G] | 3.14 | D:39 [U] | base:SC, base:SC | 72.7 | |
A:64 [GLU] | D:18 [C] | 4.36 | D:38 [G] | 72.7 | ||
A:64 [GLU] | D:38 [G] | 4.79 | D:18 [C] | 72.7 | ||
A:64 [GLU] | D:39 [U] | 2.78 | D:17 [G] | sugar:SC | 72.7 | |
A:64 [GLU] | D:40 [U] | 3.56 | D:16 [C] | base/AA stacks | 72.7 | |
A:66 [VAL] | D:41 [C] | 3.66 | E:67 [G] | 84.87 | ||
A:67 [ALA] | D:40 [U] | 4.3 | D:16 [C] | 50.58 | ||
A:67 [ALA] | D:41 [C] | 4.58 | E:67 [G] | 50.58 | ||
A:70 [LYS] | D:41 [C] | 3.55 | E:67 [G] | 85.94 | ||
A:70 [LYS] | D:42 [G] | 2.54 | E:66 [C] | 85.94 | ||
A:76 [GLU] | D:42 [G] | 4.36 | E:66 [C] | 66.67 | ||
A:77 [LYS] | D:6 [A] | 4.98 | D:49 [U] | 87.02 | ||
A:77 [LYS] | D:7 [C] | 4.84 | D:48 [G] | 87.02 | ||
A:77 [LYS] | D:42 [G] | 3.83 | E:66 [C] | 87.02 | ||
A:77 [LYS] | D:43 [C] | 2.93 | E:65 [G] | 87.02 | ||
A:78 [ALA] | D:41 [C] | 2.68 | E:67 [G] | sugar:BB | 80.96 | |
A:78 [ALA] | D:42 [G] | 3.09 | E:66 [C] | 80.96 | ||
A:79 [GLY] | D:41 [C] | 3.44 | E:67 [G] | 95.24 | ||
A:79 [GLY] | D:42 [G] | 3.78 | E:66 [C] | 95.24 | ||
A:80 [HIS] | D:41 [C] | 3.38 | E:67 [G] | base/AA stacks | 97.09 | |
A:80 [HIS] | D:42 [G] | 4.93 | E:66 [C] | 97.09 | ||
A:80 [HIS] | E:67 [G] | 4.51 | D:41 [C] | 97.09 | ||
A:81 [GLY] | E:67 [G] | 3.84 | D:41 [C] | 68.99 | ||
A:82 [GLY] | E:67 [G] | 3.3 | D:41 [C] | 97.74 | ||
A:83 [THR] | E:67 [G] | 3.32 | D:41 [C] | sugar:BB | 98.95 | |
A:83 [THR] | E:69 [G] | 3.16 | 98.95 | |||
A:85 [ASP] | E:69 [G] | 3.6 | 98.76 | |||
A:86 [PRO] | D:17 [G] | 4.6 | D:39 [U] | 97.36 | ||
A:86 [PRO] | E:69 [G] | 4.0 | 97.36 | |||
A:100 [THR] | D:42 [G] | 3.52 | E:66 [C] | 92.9 | ||
A:100 [THR] | D:43 [C] | 3.84 | E:65 [G] | 92.9 | ||
A:101 [ARG] | D:5 [C] | 2.67 | D:50 [G] | 82.95 | ||
A:101 [ARG] | D:6 [A] | 3.87 | D:49 [U] | 82.95 | ||
A:101 [ARG] | D:43 [C] | 3.69 | E:65 [G] | 82.95 | ||
A:101 [ARG] | D:44 [U] | 3.88 | E:64 [A] | 82.95 | ||
A:103 [VAL] | D:42 [G] | 4.11 | E:66 [C] | 63.86 | ||
A:103 [VAL] | D:43 [C] | 4.02 | E:65 [G] | 63.86 | ||
A:104 [GLN] | D:43 [C] | 3.24 | E:65 [G] | 53.79 | ||
A:104 [GLN] | D:44 [U] | 2.89 | E:64 [A] | 53.79 | ||
A:107 [LEU] | D:43 [C] | 4.45 | E:65 [G] | 34.49 | ||
A:107 [LEU] | E:67 [G] | 3.39 | D:41 [C] | 34.49 | ||
A:154 [ARG] | E:66 [C] | 4.63 | D:42 [G] | 95.35 | ||
A:154 [ARG] | E:67 [G] | 2.8 | D:41 [C] | 95.35 | ||
A:180 [GLY] | E:67 [G] | 4.85 | D:41 [C] | 98.44 | ||
A:182 [TYR] | E:67 [G] | 4.41 | D:41 [C] | 97.58 | ||
A:259 [LYS] | D:57 [A] | 3.92 | 59.84 | |||
A:259 [LYS] | D:58 [A] | 3.24 | 59.84 | |||
A:261 [SER] | D:57 [A] | 2.67 | sugar:SC | 62.86 | ||
A:261 [SER] | D:58 [A] | 2.9 | 62.86 | |||
A:262 [ALA] | D:57 [A] | 3.49 | 59.52 | |||
A:265 [ALA] | D:55 [A] | 3.46 | 61.43 | |||
A:265 [ALA] | D:57 [A] | 3.41 | 61.43 | |||
A:266 [VAL] | D:57 [A] | 4.61 | 67.64 | |||
A:267 [THR] | D:4 [C] | 3.77 | D:51 [G] | 55.39 | ||
A:268 [HIS] | D:3 [G] | 2.91 | D:52 [C] | base:BB | 75.83 | |
A:268 [HIS] | D:4 [C] | 4.48 | D:51 [G] | 75.83 | ||
A:268 [HIS] | D:52 [C] | 3.73 | D:3 [G] | sugar:SC | 75.83 | |
A:268 [HIS] | D:53 [C] | 3.54 | D:2 [G] | sugar:SC | 75.83 | |
A:268 [HIS] | D:55 [A] | 3.07 | 75.83 | |||
A:269 [GLY] | D:3 [G] | 2.49 | D:52 [C] | sugar:BB | 98.81 | |
A:269 [GLY] | D:4 [C] | 3.17 | D:51 [G] | 98.81 | ||
A:269 [GLY] | D:55 [A] | 3.56 | 98.81 | |||
A:270 [ALA] | D:3 [G] | 4.66 | D:52 [C] | 60.97 | ||
A:270 [ALA] | D:55 [A] | 3.49 | 60.97 | |||
A:270 [ALA] | D:57 [A] | 3.73 | 60.97 | |||
A:271 [ASP] | D:3 [G] | 4.9 | D:52 [C] | 44.04 | ||
A:271 [ASP] | D:57 [A] | 2.89 | base:BB | 44.04 | ||
A:272 [LEU] | D:57 [A] | 3.84 | 62.28 | |||
A:273 [ALA] | D:56 [C] | 3.3 | 5.99 | |||
A:273 [ALA] | D:57 [A] | 2.85 | base:BB | 5.99 | ||
A:274 [VAL] | D:57 [A] | 4.89 | 20.66 | |||
A:275 [PRO] | D:56 [C] | 3.75 | 42.04 | |||
A:275 [PRO] | D:57 [A] | 3.61 | 42.04 | |||
A:275 [PRO] | D:58 [A] | 4.17 | 42.04 | |||
A:276 [GLY] | D:57 [A] | 3.29 | 43.75 | |||
A:317 [LYS] | D:56 [C] | 3.2 | 34.16 | |||
A:318 [GLY] | D:56 [C] | 2.88 | base:BB | 61.08 | ||
A:319 [ILE] | D:56 [C] | 3.57 | 4.86 | |||
A:322 [ASP] | D:4 [C] | 4.98 | D:51 [G] | 62.31 | ||
A:323 [VAL] | D:3 [G] | 4.25 | D:52 [C] | 51.59 | ||
A:323 [VAL] | D:4 [C] | 3.44 | D:51 [G] | 51.59 | ||
A:324 [GLU] | D:4 [C] | 3.59 | D:51 [G] | 39.72 | ||
A:324 [GLU] | D:5 [C] | 3.8 | D:50 [G] | 39.72 | ||
A:324 [GLU] | D:45 [C] | 3.82 | E:63 [G] | 39.72 | ||
A:325 [LYS] | D:4 [C] | 4.54 | D:51 [G] | 72.92 | ||
A:325 [LYS] | D:5 [C] | 3.45 | D:50 [G] | 72.92 | ||
A:325 [LYS] | D:44 [U] | 2.75 | E:64 [A] | 72.92 | ||
A:325 [LYS] | D:45 [C] | 3.03 | E:63 [G] | 72.92 | ||
A:326 [VAL] | D:4 [C] | 3.74 | D:51 [G] | 88.15 | ||
A:326 [VAL] | D:5 [C] | 2.99 | D:50 [G] | 88.15 | ||
A:330 [ARG] | D:3 [G] | 3.92 | D:52 [C] | 2.77 | ||
A:330 [ARG] | D:4 [C] | 2.79 | D:51 [G] | base:SC, sugar:SC | 2.77 | |
A:330 [ARG] | D:5 [C] | 4.02 | D:50 [G] | 2.77 | ||
A:330 [ARG] | D:51 [G] | 3.93 | D:4 [C] | 2.77 | ||
A:330 [ARG] | D:52 [C] | 2.62 | D:3 [G] | base:SC, sugar:SC | 2.77 | |
A:330 [ARG] | D:53 [C] | 4.53 | D:2 [G] | 2.77 | ||
A:335 [LYS] | D:53 [C] | 3.44 | D:2 [G] | 57.14 | ||
A:336 [LEU] | D:58 [A] | 3.37 | 13.19 | |||
A:337 [TRP] | D:53 [C] | 3.49 | D:2 [G] | 45.86 | ||
A:337 [TRP] | D:54 [C] | 2.91 | D:1 [G] | 45.86 | ||
A:337 [TRP] | D:55 [A] | 3.21 | 45.86 | |||
A:337 [TRP] | D:58 [A] | 3.54 | 45.86 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group107 | 3LWR_A_D,E | A: Pseudouridine synthase cbf5, Pyrococcus furiosus (genetically engineered) D: H/aca RNA E: N/A | Q7LWY0 | PUA domain & Pseudouridine synthase | Pab160 RNA | ✘ |
Interologs
Total number of interologs for this interface: 3
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
2HVY_A_E | 3LWR_A_D,E | 0.78 | 0.94 | 0.97 | 0.5 | PUA domain & Pseudouridine synthase | compare | |
3HAX_A_E,F | 3LWR_A_D,E | 0.92 | 0.99 | 0.43 | 0.44 | PUA domain & Pseudouridine synthase | compare | |
3HJW_A_D,E | 3LWR_A_D,E | 0.97 | 0.99 | 0.47 | 0.93 | PUA domain & Pseudouridine synthase | Pab160 RNA | compare |