Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
| 6BSG_A
|
6BSG_R
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
|---|---|---|---|---|---|---|
| A:21 [VAL] | R:3 [G] | 3.31 | 69.18 | |||
| A:22 [LYS] | R:3 [G] | 3.07 | base:BB, base:BB | 72.1 | ||
| A:23 [GLN] | R:3 [G] | 3.55 | 94.97 | |||
| A:24 [TRP] | R:3 [G] | 2.71 | base:BB | base/AA stacks | 77.63 | |
| A:59 [PRO] | R:3 [G] | 3.46 | 98.65 | |||
| A:60 [VAL] | R:3 [G] | 4.26 | 80.28 | |||
| A:62 [ALA] | R:3 [G] | 3.55 | 79.64 | |||
| A:76 [ASP] | R:3 [G] | 4.1 | 98.39 | |||
| A:78 [ARG] | R:3 [G] | 3.99 | 98.44 | |||
| A:78 [ARG] | R:4 [A] | 2.67 | 98.44 | |||
| A:78 [ARG] | R:6 [G] | 4.5 | D:24 [DC] | 98.44 | ||
| A:91 [GLN] | R:9 [C] | 4.35 | D:21 [DG] | 89.18 | ||
| A:92 [LEU] | R:9 [C] | 2.73 | D:21 [DG] | sugar:BB | 75.5 | |
| A:92 [LEU] | R:10 [A] | 3.75 | D:20 [DT] | 75.5 | ||
| A:93 [GLY] | R:9 [C] | 4.85 | D:21 [DG] | 85.2 | ||
| A:93 [GLY] | R:10 [A] | 4.68 | D:20 [DT] | 85.2 | ||
| A:261 [VAL] | R:12 [A] | 4.19 | D:18 [DT] | 80.05 | ||
| A:261 [VAL] | R:13 [A] | 4.5 | D:17 [DT] | 80.05 | ||
| A:265 [ASN] | R:11 [C] | 3.16 | D:19 [DG] | sugar:SC | 89.63 | |
| A:265 [ASN] | R:12 [A] | 3.36 | D:18 [DT] | 89.63 | ||
| A:280 [CYS] | R:13 [A] | 3.52 | D:17 [DT] | 68.62 | ||
| A:280 [CYS] | R:14 [U] | 4.31 | D:16 [DA] | 68.62 | ||
| A:283 [LEU] | R:13 [A] | 3.49 | D:17 [DT] | 87.4 | ||
| A:283 [LEU] | R:14 [U] | 3.51 | D:16 [DA] | sugar:BB | 87.4 | |
| A:284 [ARG] | R:14 [U] | 3.48 | D:16 [DA] | 79.85 | ||
| A:284 [ARG] | R:15 [A] | 3.37 | D:15 [DT] | 79.85 | ||
| A:285 [GLY] | R:14 [U] | 3.74 | D:16 [DA] | 97.22 | ||
| A:285 [GLY] | R:15 [A] | 2.8 | D:15 [DT] | 97.22 | ||
| A:355 [ALA] | R:13 [A] | 4.74 | D:17 [DT] | 49.93 | ||
| A:357 [MET] | R:13 [A] | 3.75 | D:17 [DT] | 0.8 | ||
| A:357 [MET] | R:14 [U] | 3.1 | D:16 [DA] | 0.8 | ||
| A:446 [ALA] | R:25 [A] | 4.8 | D:5 [DT] | 71.31 | ||
| A:448 [ARG] | R:25 [A] | 3.91 | D:5 [DT] | base:SC | 52.65 | |
| A:448 [ARG] | R:26 [U] | 3.26 | D:4 [DA] | 52.65 | ||
| A:474 [ASN] | R:23 [G] | 4.33 | D:7 [DC] | 87.28 | ||
| A:474 [ASN] | R:24 [C] | 3.17 | D:6 [DG] | base:SC | 87.28 | |
| A:474 [ASN] | R:25 [A] | 4.87 | D:5 [DT] | 87.28 | ||
| A:475 [GLN] | R:22 [G] | 4.9 | D:8 [DC] | 93.67 | ||
| A:475 [GLN] | R:23 [G] | 3.05 | D:7 [DC] | base:SC | 93.67 | |
| A:475 [GLN] | R:24 [C] | 4.9 | D:6 [DG] | 93.67 | ||
| A:478 [GLU] | R:24 [C] | 3.4 | D:6 [DG] | 90.96 | ||
| A:498 [ASP] | R:23 [G] | 2.75 | D:7 [DC] | sugar:BB | 89.5 | |
| A:498 [ASP] | R:24 [C] | 3.49 | D:6 [DG] | 89.5 | ||
| A:498 [ASP] | R:25 [A] | 4.55 | D:5 [DT] | 89.5 | ||
| A:499 [SER] | R:23 [G] | 3.68 | D:7 [DC] | 93.51 | ||
| A:499 [SER] | R:24 [C] | 4.88 | D:6 [DG] | 93.51 | ||
| A:500 [GLN] | R:22 [G] | 3.14 | D:8 [DC] | sugar:SC | 81.37 | |
| A:500 [GLN] | R:23 [G] | 2.78 | D:7 [DC] | sugar:BB | 81.37 | |
| A:501 [TYR] | R:22 [G] | 4.88 | D:8 [DC] | 85.25 | ||
| A:501 [TYR] | R:23 [G] | 4.19 | D:7 [DC] | 85.25 | ||
| A:535 [TRP] | R:23 [G] | 3.3 | D:7 [DC] | sugar:SC | 72.34 | |
| A:535 [TRP] | R:24 [C] | 3.96 | D:6 [DG] | 72.34 | ||
| A:536 [VAL] | R:24 [C] | 4.9 | D:6 [DG] | 91.94 | ||
| A:537 [PRO] | R:23 [G] | 4.95 | D:7 [DC] | 86.51 | ||
| A:537 [PRO] | R:24 [C] | 3.51 | D:6 [DG] | 86.51 | ||
| A:538 [ALA] | R:24 [C] | 3.08 | D:6 [DG] | 84.63 | ||
| A:538 [ALA] | R:25 [A] | 3.83 | D:5 [DT] | 84.63 | ||
| A:539 [HIS] | R:24 [C] | 4.76 | D:6 [DG] | 91.62 | ||
| A:539 [HIS] | R:25 [A] | 2.73 | D:5 [DT] | 91.62 | ||
| A:549 [ASP] | R:25 [A] | 4.36 | D:5 [DT] | 90.96 | ||
| A:557 [ARG] | R:25 [A] | 2.99 | D:5 [DT] | 75.73 | ||
| A:557 [ARG] | R:26 [U] | 3.32 | D:4 [DA] | 75.73 |
Export the table of contacts
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
| Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
|---|---|---|---|---|---|---|---|
| group109 | 6BSG_A_R | A: Reverse transcriptase p66 subunit, Human immunodeficiency virus 1 (genetically engineered) R: RNA (25-mer), Homo sapiens (synthetic) | P04585 | Ribonuclease H-like & RNaseH-like domain in reverse transcriptase & Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases | ✘ |
|
Interologs
Total number of interologs for this interface: 6
| Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
|---|---|---|---|---|---|---|---|---|
| 6BSG_A_R | 6VRD_A_B | 0.59 | 0.71 | 1.55 | 0.25 | Ribonuclease H-like | compare | |
| 4H8K_A_C | 6BSG_A_R | 0.63 | 0.7 | 0.75 | 0.0 | Ribonuclease H-like | compare | |
| 2QKB_A_C | 6BSG_A_R | 0.56 | 0.7 | 1.02 | 0.0 | Ribonuclease H-like | compare | |
| 1ZBI_A_C | 6BSG_A_R | 0.52 | 0.62 | 2.08 | 0.23 | Ribonuclease H-like | compare | |
| 5VAJ_B_C | 6BSG_A_R | 0.57 | 0.61 | 1.5 | 0.0 | Ribonuclease H-like | compare | |
| 1ZBL_A_C | 6BSG_A_R | 0.55 | 0.61 | 2.22 | 0.0 | Ribonuclease H-like | compare |