Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
4W2F_B0
|
4W2F_AX,BA
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
B0:2 [ALA] | AX:76 [A] | 3.36 | base:BB | 90.17 | ||
B0:2 [ALA] | BA:2539 [A] | 3.32 | BA:2159 [G] | 90.17 | ||
B0:2 [ALA] | BA:2540 [C] | 3.74 | BA:2592 [U] | 90.17 | ||
B0:2 [ALA] | BA:2582 [G] | 3.75 | BA:2545 [U] | 90.17 | ||
B0:2 [ALA] | BA:2690 [A] | 4.11 | 90.17 | |||
B0:3 [HIS] | BA:2581 [U] | 4.35 | BA:2547 [A] | 67.74 | ||
B0:3 [HIS] | BA:2582 [G] | 2.81 | BA:2545 [U] | 67.74 | ||
B0:3 [HIS] | BA:2690 [A] | 4.53 | 67.74 | |||
B0:4 [LYS] | AX:74 [C] | 3.9 | BA:2340 [G] | 81.08 | ||
B0:4 [LYS] | AX:75 [C] | 4.64 | BA:2339 [G] | 81.08 | ||
B0:4 [LYS] | AX:76 [A] | 4.96 | 81.08 | |||
B0:4 [LYS] | BA:2339 [G] | 3.44 | AX:75 [C] | 81.08 | ||
B0:4 [LYS] | BA:2340 [G] | 3.05 | AX:74 [C] | base:SC, base:SC | 81.08 | |
B0:4 [LYS] | BA:2341 [G] | 3.46 | 81.08 | |||
B0:6 [GLY] | AX:2 [G] | 4.19 | AX:71 [C] | 70.36 | ||
B0:7 [LEU] | AX:2 [G] | 3.43 | AX:71 [C] | 42.83 | ||
B0:8 [GLY] | AX:2 [G] | 4.03 | AX:71 [C] | 73.11 | ||
B0:8 [GLY] | AX:3 [C] | 4.17 | AX:70 [G] | 73.11 | ||
B0:8 [GLY] | BA:2343 [G] | 3.14 | BA:2363 [C] | base:BB | 73.11 | |
B0:8 [GLY] | BA:2363 [C] | 4.67 | BA:2343 [G] | 73.11 | ||
B0:9 [SER] | AX:3 [C] | 3.81 | AX:70 [G] | 70.16 | ||
B0:9 [SER] | BA:2343 [G] | 3.83 | BA:2363 [C] | 70.16 | ||
B0:9 [SER] | BA:2344 [G] | 3.7 | BA:2336 [C] | 70.16 | ||
B0:10 [THR] | BA:2344 [G] | 3.92 | BA:2336 [C] | sugar:BB | 65.5 | |
B0:10 [THR] | BA:2363 [C] | 4.64 | BA:2343 [G] | 65.5 | ||
B0:10 [THR] | BA:2364 [G] | 4.7 | BA:2352 [C] | 65.5 | ||
B0:10 [THR] | BA:2365 [G] | 2.8 | BA:2351 [C] | 65.5 | ||
B0:11 [ARG] | AX:63 [G] | 3.54 | AX:51 [C] | 64.14 | ||
B0:11 [ARG] | AX:64 [G] | 3.15 | AX:50 [U] | 64.14 | ||
B0:11 [ARG] | BA:2367 [G] | 3.68 | BA:2349 [C] | 64.14 | ||
B0:12 [ASN] | BA:2365 [G] | 3.19 | BA:2351 [C] | 84.25 | ||
B0:12 [ASN] | BA:2366 [A] | 2.63 | BA:2350 [U] | 84.25 | ||
B0:12 [ASN] | BA:2367 [G] | 4.21 | BA:2349 [C] | 84.25 | ||
B0:14 [ARG] | BA:2346 [C] | 4.46 | BA:2334 [G] | 50.52 | ||
B0:14 [ARG] | BA:2348 [C] | 3.71 | BA:2368 [G] | 50.52 | ||
B0:14 [ARG] | BA:2349 [C] | 3.75 | BA:2367 [G] | 50.52 | ||
B0:14 [ARG] | BA:2350 [U] | 3.98 | BA:2366 [A] | 50.52 | ||
B0:14 [ARG] | BA:2351 [C] | 3.92 | BA:2365 [G] | base:BB | 50.52 | |
B0:14 [ARG] | BA:2365 [G] | 3.6 | BA:2351 [C] | 50.52 | ||
B0:14 [ARG] | BA:2366 [A] | 3.28 | BA:2350 [U] | 50.52 | ||
B0:14 [ARG] | BA:2367 [G] | 2.87 | BA:2349 [C] | base:SC | 50.52 | |
B0:14 [ARG] | BA:2368 [G] | 3.19 | BA:2348 [C] | 50.52 | ||
B0:15 [ASP] | BA:2349 [C] | 4.36 | BA:2367 [G] | 66.85 | ||
B0:15 [ASP] | BA:2350 [U] | 3.6 | BA:2366 [A] | 66.85 | ||
B0:15 [ASP] | BA:2351 [C] | 2.76 | BA:2365 [G] | base:SC | 66.85 | |
B0:15 [ASP] | BA:2352 [C] | 3.31 | BA:2364 [G] | 66.85 | ||
B0:15 [ASP] | BA:2353 [U] | 3.77 | BA:2362 [A] | 66.85 | ||
B0:15 [ASP] | BA:2366 [A] | 4.68 | BA:2350 [U] | 66.85 | ||
B0:16 [SER] | BA:2349 [C] | 3.45 | BA:2367 [G] | 69.02 | ||
B0:16 [SER] | BA:2350 [U] | 2.57 | BA:2366 [A] | 69.02 | ||
B0:16 [SER] | BA:2351 [C] | 4.74 | BA:2365 [G] | 69.02 | ||
B0:17 [GLN] | BA:2348 [C] | 3.44 | BA:2368 [G] | 27.41 | ||
B0:17 [GLN] | BA:2349 [C] | 2.74 | BA:2367 [G] | 27.41 | ||
B0:17 [GLN] | BA:2350 [U] | 3.34 | BA:2366 [A] | 27.41 | ||
B0:18 [ALA] | BA:2359 [G] | 3.21 | 61.37 | |||
B0:18 [ALA] | BA:2360 [U] | 3.38 | BA:2355 [A] | 61.37 | ||
B0:19 [LYS] | BA:2349 [C] | 2.73 | BA:2367 [G] | 77.61 | ||
B0:19 [LYS] | BA:2350 [U] | 2.9 | BA:2366 [A] | 77.61 | ||
B0:19 [LYS] | BA:2359 [G] | 3.59 | 77.61 | |||
B0:19 [LYS] | BA:2475 [U] | 3.66 | BA:2416 [A] | 77.61 | ||
B0:19 [LYS] | BA:2476 [A] | 4.41 | 77.61 | |||
B0:20 [ARG] | BA:2358 [G] | 3.36 | 58.63 | |||
B0:20 [ARG] | BA:2359 [G] | 2.96 | 58.63 | |||
B0:20 [ARG] | BA:2360 [U] | 4.06 | BA:2355 [A] | 58.63 | ||
B0:20 [ARG] | BA:2444 [C] | 3.18 | BA:2449 [A] | 58.63 | ||
B0:20 [ARG] | BA:2445 [U] | 2.59 | 58.63 | |||
B0:21 [LEU] | BA:2358 [G] | 3.79 | 68.75 | |||
B0:21 [LEU] | BA:2359 [G] | 4.56 | 68.75 | |||
B0:23 [VAL] | BA:980 [C] | 3.91 | BA:1042 [G] | 56.28 | ||
B0:24 [LYS] | BA:2443 [C] | 3.37 | BA:2450 [G] | 92.1 | ||
B0:24 [LYS] | BA:2444 [C] | 2.72 | BA:2449 [A] | 92.1 | ||
B0:25 [ARG] | BA:2442 [G] | 3.67 | BA:2451 [C] | 43.22 | ||
B0:25 [ARG] | BA:2443 [C] | 3.01 | BA:2450 [G] | 43.22 | ||
B0:26 [TYR] | BA:978 [G] | 3.57 | BA:1044 [U] | 28.63 | ||
B0:26 [TYR] | BA:979 [C] | 3.6 | BA:1043 [G] | 28.63 | ||
B0:26 [TYR] | BA:980 [C] | 3.35 | BA:1042 [G] | 28.63 | ||
B0:26 [TYR] | BA:1043 [G] | 3.46 | BA:979 [C] | 28.63 | ||
B0:26 [TYR] | BA:1044 [U] | 3.78 | BA:978 [G] | 28.63 | ||
B0:26 [TYR] | BA:2357 [A] | 3.93 | sugar:SC | 28.63 | ||
B0:27 [GLU] | BA:978 [G] | 2.4 | BA:1044 [U] | base:BB, sugar:SC | 57.85 | |
B0:27 [GLU] | BA:979 [C] | 3.24 | BA:1043 [G] | sugar:BB | 57.85 | |
B0:27 [GLU] | BA:1045 [C] | 4.76 | BA:977 [G] | 57.85 | ||
B0:28 [GLY] | BA:1045 [C] | 4.07 | BA:977 [G] | 82.75 | ||
B0:29 [GLN] | BA:1044 [U] | 3.18 | BA:978 [G] | 56.53 | ||
B0:29 [GLN] | BA:1045 [C] | 3.3 | BA:977 [G] | 56.53 | ||
B0:32 [ARG] | BA:2440 [A] | 4.96 | BA:2453 [G] | 35.51 | ||
B0:32 [ARG] | BA:2441 [G] | 3.5 | BA:2452 [C] | 35.51 | ||
B0:32 [ARG] | BA:2442 [G] | 4.21 | BA:2451 [C] | 35.51 | ||
B0:33 [ALA] | BA:2440 [A] | 3.45 | BA:2453 [G] | 57.67 | ||
B0:33 [ALA] | BA:2441 [G] | 3.02 | BA:2452 [C] | sugar:BB | 57.67 | |
B0:34 [GLY] | BA:2440 [A] | 3.53 | BA:2453 [G] | 93.06 | ||
B0:34 [GLY] | BA:2441 [G] | 2.47 | BA:2452 [C] | base:BB | 93.06 | |
B0:34 [GLY] | BA:2442 [G] | 4.03 | BA:2451 [C] | 93.06 | ||
B0:34 [GLY] | BA:2452 [C] | 4.94 | BA:2441 [G] | 93.06 | ||
B0:35 [ASN] | BA:2441 [G] | 2.67 | BA:2452 [C] | sugar:SC | 50.83 | |
B0:35 [ASN] | BA:2442 [G] | 3.39 | BA:2451 [C] | 50.83 | ||
B0:36 [ILE] | BA:2441 [G] | 4.31 | BA:2452 [C] | 88.91 | ||
B0:36 [ILE] | BA:2442 [G] | 2.81 | BA:2451 [C] | sugar:BB | 88.91 | |
B0:36 [ILE] | BA:2443 [C] | 3.47 | BA:2450 [G] | 88.91 | ||
B0:36 [ILE] | BA:2452 [C] | 3.89 | BA:2441 [G] | 88.91 | ||
B0:39 [ARG] | BA:2442 [G] | 3.15 | BA:2451 [C] | base:SC | 82.99 | |
B0:39 [ARG] | BA:2443 [C] | 3.13 | BA:2450 [G] | base:SC, sugar:SC | 82.99 | |
B0:39 [ARG] | BA:2450 [G] | 4.74 | BA:2443 [C] | 82.99 | ||
B0:39 [ARG] | BA:2451 [C] | 2.92 | BA:2442 [G] | base:SC, sugar:SC | 82.99 | |
B0:39 [ARG] | BA:2452 [C] | 3.59 | BA:2441 [G] | 82.99 | ||
B0:41 [ARG] | BA:2350 [U] | 4.61 | BA:2366 [A] | 64.06 | ||
B0:41 [ARG] | BA:2417 [G] | 3.92 | BA:2474 [C] | 64.06 | ||
B0:41 [ARG] | BA:2418 [G] | 2.41 | BA:2473 [C] | sugar:BB | 64.06 | |
B0:41 [ARG] | BA:2419 [G] | 3.68 | BA:2412 [C] | 64.06 | ||
B0:41 [ARG] | BA:2474 [C] | 3.96 | BA:2417 [G] | 64.06 | ||
B0:41 [ARG] | BA:2475 [U] | 3.61 | BA:2416 [A] | 64.06 | ||
B0:42 [GLY] | BA:2418 [G] | 3.5 | BA:2473 [C] | 74.63 | ||
B0:42 [GLY] | BA:2419 [G] | 3.55 | BA:2412 [C] | 74.63 | ||
B0:42 [GLY] | BA:2424 [A] | 4.83 | 74.63 | |||
B0:43 [THR] | BA:2419 [G] | 3.1 | BA:2412 [C] | sugar:BB | 68.27 | |
B0:43 [THR] | BA:2420 [U] | 3.52 | BA:2411 [G] | 68.27 | ||
B0:43 [THR] | BA:2424 [A] | 3.11 | 68.27 | |||
B0:44 [ARG] | BA:981 [U] | 4.79 | BA:1041 [G] | 55.83 | ||
B0:44 [ARG] | BA:982 [G] | 4.21 | 55.83 | |||
B0:44 [ARG] | BA:2418 [G] | 3.27 | BA:2473 [C] | 55.83 | ||
B0:44 [ARG] | BA:2419 [G] | 3.92 | BA:2412 [C] | 55.83 | ||
B0:45 [PHE] | BA:980 [C] | 3.95 | BA:1042 [G] | 44.39 | ||
B0:45 [PHE] | BA:981 [U] | 3.87 | BA:1041 [G] | 44.39 | ||
B0:46 [LYS] | BA:2420 [U] | 4.23 | BA:2411 [G] | 58.25 | ||
B0:53 [MET] | BA:2453 [G] | 4.88 | BA:2440 [A] | 38.2 | ||
B0:54 [GLY] | BA:2452 [C] | 3.4 | BA:2441 [G] | 75.06 | ||
B0:54 [GLY] | BA:2453 [G] | 3.16 | BA:2440 [A] | 75.06 | ||
B0:55 [ARG] | BA:2452 [C] | 2.69 | BA:2441 [G] | 58.68 | ||
B0:55 [ARG] | BA:2453 [G] | 2.92 | BA:2440 [A] | 58.68 | ||
B0:55 [ARG] | BA:2471 [G] | 4.41 | BA:2373 [C] | 58.68 | ||
B0:55 [ARG] | BA:2472 [G] | 2.33 | BA:2372 [C] | 58.68 | ||
B0:55 [ARG] | BA:2473 [C] | 4.69 | BA:2418 [G] | 58.68 | ||
B0:55 [ARG] | BA:2474 [C] | 3.36 | BA:2417 [G] | 58.68 | ||
B0:55 [ARG] | BA:2475 [U] | 2.74 | BA:2416 [A] | 58.68 | ||
B0:56 [ASP] | BA:2451 [C] | 3.58 | BA:2442 [G] | 80.31 | ||
B0:56 [ASP] | BA:2452 [C] | 3.2 | BA:2441 [G] | 80.31 | ||
B0:56 [ASP] | BA:2474 [C] | 4.1 | BA:2417 [G] | 80.31 | ||
B0:56 [ASP] | BA:2475 [U] | 4.92 | BA:2416 [A] | 80.31 | ||
B0:57 [PHE] | BA:2418 [G] | 3.96 | BA:2473 [C] | 46.3 | ||
B0:57 [PHE] | BA:2419 [G] | 4.55 | BA:2412 [C] | 46.3 | ||
B0:57 [PHE] | BA:2424 [A] | 3.63 | 46.3 | |||
B0:57 [PHE] | BA:2473 [C] | 3.4 | BA:2418 [G] | 46.3 | ||
B0:57 [PHE] | BA:2474 [C] | 3.39 | BA:2417 [G] | 46.3 | ||
B0:58 [THR] | BA:2452 [C] | 3.71 | BA:2441 [G] | 90.6 | ||
B0:60 [PHE] | BA:2452 [C] | 4.25 | BA:2441 [G] | 40.95 | ||
B0:60 [PHE] | BA:2453 [G] | 3.5 | BA:2440 [A] | 40.95 | ||
B0:60 [PHE] | BA:2454 [A] | 3.94 | BA:2439 [G] | 40.95 | ||
B0:62 [LEU] | BA:2454 [A] | 3.83 | BA:2439 [G] | 31.96 | ||
B0:69 [PHE] | BA:979 [C] | 3.29 | BA:1043 [G] | 68.47 | ||
B0:69 [PHE] | BA:980 [C] | 3.65 | BA:1042 [G] | 68.47 | ||
B0:74 [ARG] | BA:2422 [G] | 2.5 | base:SC, base:SC, base:SC | 18.13 | ||
B0:75 [LEU] | BA:2422 [G] | 3.38 | 11.51 | |||
B0:77 [ARG] | BA:980 [C] | 2.76 | BA:1042 [G] | 48.32 | ||
B0:77 [ARG] | BA:981 [U] | 2.97 | BA:1041 [G] | 48.32 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group119 | 4W2F_B0_AX,BA | B0: 50s ribosomal protein l27, Thermus thermophilus (natural) AX: E-site tRNA, Escherichia coli (genetically engineered) BA: 23s ribosomal RNA, Thermus thermophilus (natural) | P60493 | Ribosomal L27 protein | tRNA & Bacterial large subunit ribosomal RNA | ✔ |
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Interologs
Total number of interologs for this interface: 7
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
4W2F_B0_AX,BA | 7OF0_W_A | 0.83 | 0.94 | 1.73 | 0.26 | Ribosomal L27 protein | Bacterial large subunit ribosomal RNA | compare |
4W2F_B0_AX,BA | 6S0Z_U_A | 0.85 | 0.96 | 0.92 | 0.56 | Ribosomal L27 protein | Bacterial large subunit ribosomal RNA | compare |
4W2F_B0_AX,BA | 7N1P_La_23,Dt | 0.90 | 0.95 | 1.41 | 0.56 | Ribosomal L27 protein | Bacterial large subunit ribosomal RNA & tRNA | compare |
4W2F_B0_AX,BA | 7K00_v_a | 0.92 | 0.96 | 0.87 | 0.62 | Ribosomal L27 protein | Bacterial large subunit ribosomal RNA | compare |
4W2F_B0_AX,BA | 7RYG_V_A | 0.94 | 0.96 | 2.3 | 0.65 | Ribosomal L27 protein | Bacterial large subunit ribosomal RNA | compare |
4W2F_B0_AX,BA | 6XHV_10_1A,1x | 0.99 | 0.97 | 0.74 | 0.88 | Ribosomal L27 protein | Bacterial large subunit ribosomal RNA & tRNA | compare |
4W2F_B0_AX,BA | 4Y4O_10_1A | 0.99 | 0.99 | 0.88 | 0.98 | Ribosomal L27 protein | Bacterial large subunit ribosomal RNA | compare |