RNAprotDB

All interfaces > All interologs > Interface groups > group130 > 4K4Z_E_F,G

Interface analysis

mouse controls

Style

Protein

Cartoon
Licorice
Surface

RNA

Cartoon
Licorice
Surface

Color

Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

View

Focus on

Interface
RNA
Protein
All

Show chains

Interface

show as licorice
show Accessibility
Rim - Core

Contacts -

4K4Z_E
4K4Z_F,G
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
E:17 [ILE] F:598 [A] 4.7 79.2
E:18 [ASN] F:598 [A] 3.18 sugar:BB base/AA stacks 73.43
E:20 [PRO] F:598 [A] 3.28 74.6
E:20 [PRO] F:599 [G] 3.41 74.6
E:22 [LYS] F:599 [G] 3.16 base:BB, base:BB 63.71
E:23 [THR] F:599 [G] 4.53 90.25
E:24 [LYS] F:598 [A] 4.82 51.52
E:24 [LYS] F:599 [G] 3.02 51.52
E:43 [LEU] F:599 [G] 3.53 95.32
E:102 [TYR] G:1306 [A] 4.71 F:608 [U] 68.39
E:106 [GLY] F:603 [U] 4.02 G:1311 [A] 52.12
E:107 [LEU] F:602 [C] 4.67 G:1312 [G] 81.2
E:107 [LEU] F:603 [U] 3.74 G:1311 [A] 81.2
E:108 [GLU] F:603 [U] 3.17 G:1311 [A] 75.77
E:108 [GLU] F:604 [C] 4.67 G:1310 [G] 75.77
E:110 [LEU] F:602 [C] 4.07 G:1312 [G] 81.5
E:111 [ASP] F:601 [U] 4.11 G:1313 [A] 92.01
E:112 [LEU] G:1307 [C] 4.83 F:607 [G] 82.1
E:113 [THR] F:600 [G] 4.93 53.83
E:113 [THR] G:1308 [G] 3.37 F:606 [C] 53.83
E:114 [THR] F:600 [G] 3.53 93.4
E:114 [THR] F:601 [U] 2.67 G:1313 [A] 93.4
E:115 [SER] F:599 [G] 2.71 96.52
E:115 [SER] F:600 [G] 2.76 96.52
E:115 [SER] F:601 [U] 4.27 G:1313 [A] 96.52
E:121 [VAL] F:598 [A] 4.46 64.37
E:121 [VAL] F:599 [G] 3.53 64.37
E:126 [LYS] F:597 [C] 4.84 H:1 [G] 75.03
E:127 [LYS] F:600 [G] 4.39 95.32
E:127 [LYS] F:601 [U] 2.86 G:1313 [A] 95.32
E:128 [ARG] G:1306 [A] 4.94 F:608 [U] 63.12
E:128 [ARG] G:1307 [C] 2.56 F:607 [G] 63.12
E:128 [ARG] G:1308 [G] 4.72 F:606 [C] 63.12
E:133 [LYS] G:1306 [A] 3.85 F:608 [U] 0.13
E:133 [LYS] G:1307 [C] 2.62 F:607 [G] 0.13
E:134 [LYS] G:1306 [A] 4.21 F:608 [U] 18.38
E:157 [TYR] F:598 [A] 4.7 77.63
E:157 [TYR] F:599 [G] 3.37 77.63
E:158 [VAL] F:599 [G] 4.86 85.68
E:159 [LYS] F:600 [G] 3.19 98.92
E:159 [LYS] G:1313 [A] 4.87 F:601 [U] 98.92
E:160 [ASP] F:599 [G] 3.65 98.97
E:176 [ILE] F:599 [G] 3.41 89.77
E:176 [ILE] F:600 [G] 3.3 89.77
E:177 [GLU] F:600 [G] 3.51 sugar:BB 89.56
E:178 [ALA] F:600 [G] 3.44 81.94
E:179 [SER] F:600 [G] 3.28 sugar:BB 83.28
E:179 [SER] F:601 [U] 4.57 G:1313 [A] 83.28
E:184 [SER] F:601 [U] 4.14 G:1313 [A] 83.01
E:184 [SER] F:602 [C] 4.79 G:1312 [G] 83.01
E:188 [ARG] F:601 [U] 4.98 G:1313 [A] 96.49
E:188 [ARG] F:602 [C] 3.01 G:1312 [G] 96.49
E:195 [TYR] F:602 [C] 4.41 G:1312 [G] 62.82
E:199 [HIS] F:602 [C] 3.52 G:1312 [G] 78.47
E:199 [HIS] F:603 [U] 3.39 G:1311 [A] 78.47
E:209 [ALA] F:603 [U] 4.94 G:1311 [A] 97.8
E:210 [VAL] F:602 [C] 3.89 G:1312 [G] 92.71
E:210 [VAL] F:603 [U] 3.69 G:1311 [A] 92.71
E:211 [GLY] F:603 [U] 2.84 G:1311 [A] sugar:BB 98.79
E:211 [GLY] F:604 [C] 3.44 G:1310 [G] 98.79
E:212 [CYS] F:603 [U] 3.73 G:1311 [A] 81.37
E:212 [CYS] F:604 [C] 3.22 G:1310 [G] 81.37
E:213 [ASP] F:604 [C] 3.35 G:1310 [G] 76.49
E:213 [ASP] F:605 [U] 3.52 G:1309 [A] 76.49
E:214 [PRO] F:604 [C] 4.09 G:1310 [G] 95.19
E:289 [SER] F:600 [G] 3.45 99.0
E:290 [GLY] F:600 [G] 2.53 sugar:BB 98.81
E:290 [GLY] F:601 [U] 2.92 G:1313 [A] 98.81
E:291 [CYS] F:600 [G] 4.67 78.46
E:291 [CYS] F:601 [U] 2.78 G:1313 [A] sugar:BB 78.46
E:292 [SER] F:601 [U] 3.37 G:1313 [A] 87.39
E:292 [SER] F:602 [C] 2.69 G:1312 [G] 87.39
E:293 [GLY] F:601 [U] 3.43 G:1313 [A] 81.68
E:293 [GLY] F:602 [C] 4.56 G:1312 [G] 81.68
E:294 [THR] F:600 [G] 4.77 99.0
E:294 [THR] F:601 [U] 3.8 G:1313 [A] 99.0
E:295 [SER] F:601 [U] 4.49 G:1313 [A] 94.31
E:295 [SER] F:602 [C] 4.32 G:1312 [G] 94.31
E:295 [SER] G:1313 [A] 3.6 F:601 [U] base:SC 94.31
E:327 [TYR] F:602 [C] 4.02 G:1312 [G] 98.17
E:327 [TYR] F:603 [U] 3.3 G:1311 [A] 98.17
E:327 [TYR] G:1312 [G] 3.08 F:602 [C] base:SC 98.17
E:327 [TYR] G:1313 [A] 2.62 F:601 [U] sugar:BB 98.17
E:328 [GLY] G:1313 [A] 3.43 F:601 [U] 98.39
E:329 [ASP] G:1313 [A] 2.67 F:601 [U] 98.97
E:330 [ASP] G:1313 [A] 3.49 F:601 [U] 98.97
E:375 [LEU] G:1312 [G] 3.24 F:602 [C] 98.41
E:375 [LEU] G:1313 [A] 4.15 F:601 [U] 98.41
E:376 [LYS] G:1312 [G] 2.55 F:602 [C] 98.92
E:376 [LYS] G:1313 [A] 3.99 F:601 [U] 98.92
E:377 [ARG] G:1311 [A] 4.06 F:603 [U] 98.97
E:377 [ARG] G:1312 [G] 3.83 F:602 [C] sugar:SC 98.97
E:393 [MET] G:1311 [A] 4.14 F:603 [U] 85.28
E:393 [MET] G:1312 [G] 3.86 F:602 [C] 85.28
E:397 [ASP] G:1312 [G] 5.0 F:602 [C] 79.31
E:401 [SER] G:1310 [G] 3.38 F:604 [C] 87.4
E:401 [SER] G:1311 [A] 2.54 F:603 [U] 87.4
E:406 [LYS] G:1310 [G] 4.08 F:604 [C] 83.49
E:409 [LYS] G:1308 [G] 4.22 F:606 [C] 60.1
E:409 [LYS] G:1309 [A] 4.51 F:605 [U] 60.1
E:410 [ASN] G:1308 [G] 4.26 F:606 [C] 59.6
E:410 [ASN] G:1309 [A] 3.57 F:605 [U] 59.6
E:410 [ASN] G:1310 [G] 4.96 F:604 [C] 59.6
E:413 [ASP] F:607 [G] 3.51 G:1307 [C] sugar:SC 70.28
E:413 [ASP] G:1308 [G] 3.34 F:606 [C] 70.28
E:413 [ASP] G:1309 [A] 3.54 F:605 [U] 70.28
E:413 [ASP] G:1310 [G] 4.83 F:604 [C] 70.28
E:414 [HIS] G:1309 [A] 3.72 F:605 [U] 83.55
E:414 [HIS] G:1310 [G] 3.63 F:604 [C] 83.55
E:414 [HIS] G:1311 [A] 4.45 F:603 [U] 83.55
E:416 [ARG] F:606 [C] 2.92 G:1308 [G] sugar:SC 2.48
E:416 [ARG] F:607 [G] 3.09 G:1307 [C] 2.48
E:417 [SER] F:605 [U] 5.0 G:1309 [A] 93.13
E:417 [SER] F:606 [C] 4.14 G:1308 [G] 93.13
E:417 [SER] G:1309 [A] 4.41 F:605 [U] 93.13
E:417 [SER] G:1310 [G] 3.67 F:604 [C] 93.13
E:418 [LEU] G:1310 [G] 3.87 F:604 [C] 84.94
E:418 [LEU] G:1311 [A] 4.29 F:603 [U] 84.94
E:420 [LEU] F:605 [U] 3.7 G:1309 [A] 3.01
E:420 [LEU] F:606 [C] 3.38 G:1308 [G] 3.01
E:421 [LEU] G:1310 [G] 4.87 F:604 [C] 91.43
E:421 [LEU] G:1311 [A] 3.99 F:603 [U] 91.43
E:457 [LYS] F:607 [G] 4.43 G:1307 [C] 7.57

logo_download Export the table of contacts

*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group130 4K4Z_E_F,G E: RNA-dependent RNA polymerase, Human coxsackievirus b3 (genetically engineered) F: N/A G: N/A Q5UEA2 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases ✘

Interologs

Total number of interologs for this interface: 10

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4K4S_A_B,C 4K4Z_E_F,G 0.95 0.99 0.41 0.91 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3OL9_A_B,C 4K4Z_E_F,G 0.95 0.99 0.51 0.92 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3AVX_A_G,T 4K4Z_E_F,G 0.61 0.61 2.51 0.09 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 5F8H_A_B,C 0.95 0.99 0.39 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 5Y6Z_A_B,C 0.90 0.98 0.73 0.87 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 6KWQ_A_B,C 0.92 0.98 0.55 0.77 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 6LSF_A_B,C 0.87 0.99 0.7 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 6LSG_A_B,C 0.80 0.99 0.69 0.8 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 7AAP_A_T 0.61 0.79 1.77 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
4K4Z_E_F,G 7BV2_A_T 0.60 0.79 1.53 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare