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All interfaces > All interologs > Interface groups > group130 > 5F8H_A_B,C

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Licorice
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Licorice
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Chain
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Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

5F8H_A
5F8H_B,C
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:20 [PRO] B:599 [G] 3.36 70.12
A:22 [ARG] B:599 [G] 3.76 base:BB 67.89
A:23 [THR] B:599 [G] 4.93 92.17
A:24 [LYS] B:599 [G] 3.39 base:SC 53.87
A:43 [LEU] B:599 [G] 4.14 92.86
A:106 [ASN] B:603 [U] 4.52 C:1309 [A] 52.18
A:107 [LEU] B:602 [C] 4.74 C:1310 [G] 84.81
A:107 [LEU] B:603 [U] 3.92 C:1309 [A] 84.81
A:108 [GLU] B:603 [U] 3.19 C:1309 [A] 78.89
A:110 [ILE] B:601 [U] 4.64 C:1311 [A] 77.32
A:110 [ILE] B:602 [C] 4.88 C:1310 [G] 77.32
A:111 [ASP] B:601 [U] 4.32 C:1311 [A] 90.9
A:111 [ASP] B:602 [C] 4.92 C:1310 [G] 90.9
A:113 [HIS] B:600 [G] 4.96 54.98
A:113 [HIS] C:1305 [A] 3.9 B:607 [U] 54.98
A:113 [HIS] C:1306 [G] 2.83 B:606 [C] 54.98
A:114 [THR] B:600 [G] 3.46 94.2
A:114 [THR] B:601 [U] 2.82 C:1311 [A] 94.2
A:115 [SER] B:599 [G] 2.86 95.94
A:115 [SER] B:600 [G] 2.76 95.94
A:115 [SER] B:601 [U] 4.3 C:1311 [A] 95.94
A:121 [SER] B:599 [G] 3.22 59.26
A:127 [LYS] B:600 [G] 4.26 97.6
A:127 [LYS] B:601 [U] 2.55 C:1311 [A] 97.6
A:128 [ARG] C:1305 [A] 2.99 B:607 [U] 61.06
A:133 [SER] C:1304 [G] 3.63 B:608 [C] 0.45
A:157 [TYR] B:599 [G] 3.48 76.07
A:158 [VAL] B:599 [G] 4.82 82.87
A:159 [LYS] B:600 [G] 2.89 base:SC 98.89
A:159 [LYS] C:1311 [A] 3.98 B:601 [U] 98.89
A:160 [ASP] B:599 [G] 3.49 98.95
A:176 [ILE] B:599 [G] 3.34 90.56
A:176 [ILE] B:600 [G] 3.38 90.56
A:177 [GLU] B:600 [G] 3.69 sugar:BB 91.69
A:178 [ALA] B:600 [G] 3.36 85.63
A:179 [SER] B:600 [G] 3.27 sugar:BB 83.51
A:179 [SER] B:601 [U] 4.69 C:1311 [A] 83.51
A:184 [SER] B:601 [U] 4.05 C:1311 [A] 82.59
A:188 [ARG] B:601 [U] 4.76 C:1311 [A] 96.49
A:188 [ARG] B:602 [C] 2.73 C:1310 [G] 96.49
A:195 [TYR] B:602 [C] 4.71 C:1310 [G] 63.08
A:199 [HIS] B:602 [C] 3.5 C:1310 [G] 81.59
A:199 [HIS] B:603 [U] 3.12 C:1309 [A] 81.59
A:209 [ALA] B:603 [U] 4.96 C:1309 [A] 97.0
A:210 [VAL] B:602 [C] 4.18 C:1310 [G] 94.49
A:210 [VAL] B:603 [U] 3.99 C:1309 [A] 94.49
A:211 [GLY] B:603 [U] 2.97 C:1309 [A] sugar:BB 98.76
A:211 [GLY] B:604 [C] 3.35 C:1308 [G] 98.76
A:212 [CYS] B:603 [U] 4.02 C:1309 [A] 87.26
A:212 [CYS] B:604 [C] 3.04 C:1308 [G] 87.26
A:213 [ASN] B:604 [C] 3.08 C:1308 [G] 80.64
A:213 [ASN] B:605 [U] 3.48 C:1307 [A] 80.64
A:214 [PRO] B:604 [C] 3.95 C:1308 [G] 98.42
A:215 [ASP] B:605 [U] 4.91 C:1307 [A] 84.12
A:289 [SER] B:600 [G] 2.36 base:BB 99.0
A:289 [SER] B:601 [U] 4.44 C:1311 [A] 99.0
A:290 [GLY] B:600 [G] 2.65 sugar:BB 98.76
A:290 [GLY] B:601 [U] 2.89 C:1311 [A] 98.76
A:291 [CYS] B:600 [G] 4.71 80.94
A:291 [CYS] B:601 [U] 2.83 C:1311 [A] sugar:BB 80.94
A:292 [SER] B:601 [U] 3.4 C:1311 [A] 89.32
A:292 [SER] B:602 [C] 3.21 C:1310 [G] 89.32
A:293 [GLY] B:601 [U] 3.36 C:1311 [A] 86.43
A:293 [GLY] B:602 [C] 4.83 C:1310 [G] 86.43
A:294 [THR] B:600 [G] 4.63 98.97
A:294 [THR] B:601 [U] 3.71 C:1311 [A] 98.97
A:295 [SER] B:601 [U] 4.68 C:1311 [A] 96.1
A:295 [SER] B:602 [C] 4.4 C:1310 [G] 96.1
A:295 [SER] C:1311 [A] 3.42 B:601 [U] base:SC 96.1
A:327 [TYR] B:602 [C] 4.19 C:1310 [G] 98.71
A:327 [TYR] B:603 [U] 3.27 C:1309 [A] 98.71
A:327 [TYR] C:1310 [G] 3.17 B:602 [C] base:SC 98.71
A:327 [TYR] C:1311 [A] 2.76 B:601 [U] sugar:BB 98.71
A:328 [GLY] C:1311 [A] 3.28 B:601 [U] 98.29
A:329 [ASP] C:1311 [A] 2.8 B:601 [U] 98.95
A:330 [ASP] C:1311 [A] 3.4 B:601 [U] 98.95
A:375 [LEU] C:1310 [G] 3.37 B:602 [C] 98.74
A:375 [LEU] C:1311 [A] 3.84 B:601 [U] 98.74
A:376 [LYS] C:1309 [A] 4.84 B:603 [U] 98.68
A:376 [LYS] C:1310 [G] 2.38 B:602 [C] 98.68
A:376 [LYS] C:1311 [A] 3.72 B:601 [U] 98.68
A:377 [ARG] C:1309 [A] 4.21 B:603 [U] 98.79
A:377 [ARG] C:1310 [G] 3.67 B:602 [C] sugar:SC 98.79
A:393 [MET] C:1309 [A] 3.74 B:603 [U] 85.56
A:393 [MET] C:1310 [G] 3.65 B:602 [C] 85.56
A:397 [GLU] C:1310 [G] 4.58 B:602 [C] 80.12
A:401 [SER] C:1308 [G] 3.46 B:604 [C] 87.2
A:401 [SER] C:1309 [A] 2.6 B:603 [U] 87.2
A:406 [LYS] C:1308 [G] 4.43 B:604 [C] 82.94
A:410 [ASN] C:1306 [G] 4.12 B:606 [C] 57.42
A:410 [ASN] C:1307 [A] 3.12 B:605 [U] 57.42
A:413 [ASP] B:606 [C] 4.72 C:1306 [G] 70.57
A:413 [ASP] B:607 [U] 3.61 C:1305 [A] sugar:SC 70.57
A:413 [ASP] C:1306 [G] 3.13 B:606 [C] base:SC 70.57
A:413 [ASP] C:1307 [A] 3.63 B:605 [U] 70.57
A:413 [ASP] C:1308 [G] 4.88 B:604 [C] 70.57
A:414 [HIS] C:1307 [A] 3.89 B:605 [U] 83.85
A:414 [HIS] C:1308 [G] 3.48 B:604 [C] 83.85
A:414 [HIS] C:1309 [A] 4.2 B:603 [U] 83.85
A:416 [ARG] B:606 [C] 3.34 C:1306 [G] 5.35
A:416 [ARG] B:607 [U] 4.09 C:1305 [A] 5.35
A:417 [SER] C:1307 [A] 4.49 B:605 [U] 93.67
A:417 [SER] C:1308 [G] 3.32 B:604 [C] 93.67
A:418 [LEU] C:1308 [G] 3.96 B:604 [C] 83.52
A:418 [LEU] C:1309 [A] 4.29 B:603 [U] 83.52
A:420 [LEU] B:605 [U] 3.49 C:1307 [A] 5.85
A:420 [LEU] B:606 [C] 3.49 C:1306 [G] 5.85
A:421 [LEU] C:1308 [G] 4.98 B:604 [C] 95.1
A:421 [LEU] C:1309 [A] 3.79 B:603 [U] 95.1

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group130 5F8H_A_B,C A: Genome polyprotein, Enterovirus a71 (genetically engineered) B: RNA (35-mer), Synthetic construct (synthetic) C: Synthetic construct (synthetic) E5RPG2 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases ✘

Interologs

Total number of interologs for this interface: 10

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4K4Z_E_F,G 5F8H_A_B,C 0.95 0.99 0.39 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 5F8H_A_B,C 0.92 0.99 0.44 0.85 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 6LSG_A_B,C 0.86 0.99 0.6 0.91 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 5Y6Z_A_B,C 0.97 0.98 0.61 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 6LSF_A_B,C 0.94 0.99 0.49 0.65 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 6KWQ_A_B,C 0.97 1.0 0.33 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3OL9_A_B,C 5F8H_A_B,C 0.94 0.99 0.48 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3AVX_A_G,T 5F8H_A_B,C 0.63 0.61 2.25 0.06 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 7AAP_A_T 0.70 0.8 1.58 0.09 Adenylyl and guanylyl cyclase catalytic domain-like compare
5F8H_A_B,C 7BV2_A_T 0.70 0.8 1.27 0.1 Adenylyl and guanylyl cyclase catalytic domain-like compare