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All interfaces > All interologs > Interface groups > group130 > 5Y6Z_A_B,C

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Licorice
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RNA

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Licorice
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Chain
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Hydrophobicity
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Conservation*

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Rim - Core

Contacts -

5Y6Z_A
5Y6Z_B,C
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:18 [ASN] B:598 [A] 3.94 81.79
A:19 [GLY] B:598 [A] 4.06 73.37
A:20 [PRO] B:598 [A] 3.56 70.0
A:20 [PRO] B:599 [G] 3.64 70.0
A:22 [ARG] B:599 [G] 3.52 67.5
A:23 [THR] B:599 [G] 4.8 88.19
A:24 [LYS] B:599 [G] 4.5 53.76
A:43 [LEU] B:599 [G] 3.66 95.08
A:106 [TYR] B:603 [U] 4.88 C:1310 [A] 45.14
A:108 [GLU] B:603 [U] 3.5 C:1310 [A] 77.49
A:110 [ILE] B:601 [U] 4.92 C:1312 [A] 82.19
A:111 [ASP] B:601 [U] 4.19 C:1312 [A] 94.38
A:111 [ASP] B:602 [C] 4.77 C:1311 [G] 94.38
A:113 [HIS] B:600 [G] 4.97 58.55
A:113 [HIS] C:1306 [C] 2.77 B:607 [G] 58.55
A:113 [HIS] C:1307 [G] 3.77 B:606 [C] 58.55
A:114 [THR] B:599 [G] 4.36 95.13
A:114 [THR] B:600 [G] 3.27 95.13
A:114 [THR] B:601 [U] 2.69 C:1312 [A] 95.13
A:115 [SER] B:599 [G] 2.85 97.15
A:115 [SER] B:600 [G] 2.82 97.15
A:115 [SER] B:601 [U] 4.45 C:1312 [A] 97.15
A:121 [SER] B:599 [G] 3.82 66.06
A:126 [LYS] B:597 [C] 3.89 79.4
A:126 [LYS] B:598 [A] 3.65 79.4
A:127 [LYS] B:600 [G] 4.27 98.6
A:127 [LYS] B:601 [U] 2.73 C:1312 [A] 98.6
A:157 [TYR] B:598 [A] 4.93 78.98
A:157 [TYR] B:599 [G] 3.39 78.98
A:158 [VAL] B:599 [G] 4.93 85.78
A:159 [LYS] B:600 [G] 2.84 base:SC 98.87
A:160 [ASP] B:599 [G] 3.73 98.92
A:176 [ILE] B:599 [G] 4.83 91.37
A:176 [ILE] B:600 [G] 3.36 91.37
A:177 [GLU] B:600 [G] 3.98 sugar:BB 94.57
A:178 [ALA] B:600 [G] 3.43 87.07
A:179 [SER] B:600 [G] 3.21 sugar:BB 88.55
A:179 [SER] B:601 [U] 4.69 C:1312 [A] 88.55
A:184 [SER] B:601 [U] 4.13 C:1312 [A] 82.13
A:188 [ARG] B:602 [C] 2.64 C:1311 [G] 96.12
A:199 [HIS] B:602 [C] 3.65 C:1311 [G] 83.0
A:199 [HIS] B:603 [U] 3.44 C:1310 [A] 83.0
A:209 [ALA] B:603 [U] 4.94 C:1310 [A] 97.74
A:210 [VAL] B:602 [C] 4.24 C:1311 [G] 94.51
A:210 [VAL] B:603 [U] 3.9 C:1310 [A] 94.51
A:211 [GLY] B:603 [U] 2.85 C:1310 [A] sugar:BB 98.06
A:211 [GLY] B:604 [C] 3.56 C:1309 [G] 98.06
A:212 [CYS] B:603 [U] 3.81 C:1310 [A] sugar:BB 85.28
A:212 [CYS] B:604 [C] 3.18 C:1309 [G] 85.28
A:213 [ASN] B:604 [C] 3.18 C:1309 [G] 78.74
A:213 [ASN] B:605 [U] 3.51 C:1308 [A] 78.74
A:214 [PRO] B:604 [C] 4.15 C:1309 [G] 98.22
A:289 [SER] B:600 [G] 3.26 base:BB 99.0
A:289 [SER] B:601 [U] 4.35 C:1312 [A] 99.0
A:290 [GLY] B:600 [G] 2.52 sugar:BB 98.7
A:290 [GLY] B:601 [U] 2.78 C:1312 [A] 98.7
A:291 [CYS] B:600 [G] 4.59 81.76
A:291 [CYS] B:601 [U] 2.96 C:1312 [A] sugar:BB 81.76
A:292 [SER] B:601 [U] 3.41 C:1312 [A] 90.83
A:292 [SER] B:602 [C] 4.76 C:1311 [G] 90.83
A:293 [GLY] B:601 [U] 3.28 C:1312 [A] sugar:BB 88.8
A:294 [THR] B:600 [G] 4.56 99.0
A:294 [THR] B:601 [U] 3.15 C:1312 [A] 99.0
A:295 [SER] B:601 [U] 4.54 C:1312 [A] 96.74
A:295 [SER] B:602 [C] 4.57 C:1311 [G] 96.74
A:295 [SER] C:1312 [A] 3.07 B:601 [U] base:SC 96.74
A:327 [TYR] B:602 [C] 4.05 C:1311 [G] 98.62
A:327 [TYR] B:603 [U] 3.17 C:1310 [A] 98.62
A:327 [TYR] C:1311 [G] 3.01 B:602 [C] base:SC 98.62
A:327 [TYR] C:1312 [A] 2.79 B:601 [U] 98.62
A:328 [GLY] C:1312 [A] 3.35 B:601 [U] 98.01
A:329 [ASP] C:1312 [A] 2.67 B:601 [U] 98.92
A:330 [ASP] C:1312 [A] 3.74 B:601 [U] 98.92
A:375 [LEU] C:1311 [G] 3.61 B:602 [C] 98.68
A:375 [LEU] C:1312 [A] 3.92 B:601 [U] 98.68
A:376 [LYS] C:1311 [G] 4.0 B:602 [C] 98.49
A:376 [LYS] C:1312 [A] 3.71 B:601 [U] 98.49
A:377 [ARG] C:1310 [A] 3.74 B:603 [U] 98.62
A:377 [ARG] C:1311 [G] 3.71 B:602 [C] sugar:SC 98.62
A:393 [MET] C:1310 [A] 3.51 B:603 [U] 84.43
A:393 [MET] C:1311 [G] 4.1 B:602 [C] 84.43
A:397 [GLU] C:1311 [G] 4.53 B:602 [C] 77.21
A:401 [SER] C:1309 [G] 3.41 B:604 [C] 89.93
A:401 [SER] C:1310 [A] 2.63 B:603 [U] 89.93
A:406 [LYS] C:1309 [G] 3.28 B:604 [C] 81.2
A:410 [ASN] C:1307 [G] 3.56 B:606 [C] sugar:SC 53.49
A:410 [ASN] C:1308 [A] 3.26 B:605 [U] 53.49
A:413 [ASP] B:606 [C] 4.93 C:1307 [G] 73.34
A:413 [ASP] B:607 [G] 3.5 C:1306 [C] sugar:SC 73.34
A:413 [ASP] C:1307 [G] 3.17 B:606 [C] base:SC 73.34
A:413 [ASP] C:1308 [A] 3.62 B:605 [U] 73.34
A:413 [ASP] C:1309 [G] 4.77 B:604 [C] 73.34
A:414 [HIS] C:1308 [A] 3.57 B:605 [U] 82.08
A:414 [HIS] C:1309 [G] 3.47 B:604 [C] 82.08
A:414 [HIS] C:1310 [A] 4.28 B:603 [U] 82.08
A:416 [ARG] B:606 [C] 2.88 C:1307 [G] sugar:SC 26.01
A:416 [ARG] B:607 [G] 3.0 C:1306 [C] 26.01
A:417 [SER] B:605 [U] 4.73 C:1308 [A] 94.38
A:417 [SER] B:606 [C] 4.46 C:1307 [G] 94.38
A:417 [SER] C:1308 [A] 4.37 B:605 [U] 94.38
A:417 [SER] C:1309 [G] 3.48 B:604 [C] 94.38
A:418 [LEU] C:1309 [G] 3.84 B:604 [C] 84.47
A:418 [LEU] C:1310 [A] 3.97 B:603 [U] 84.47
A:420 [LEU] B:605 [U] 3.66 C:1308 [A] 26.77
A:420 [LEU] B:606 [C] 3.38 C:1307 [G] 26.77
A:421 [LEU] C:1309 [G] 4.29 B:604 [C] 93.6
A:421 [LEU] C:1310 [A] 3.76 B:603 [U] 93.6

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group130 5Y6Z_A_B,C A: Genome polyprotein, Coxsackievirus a16 (genetically engineered) B: Template RNA (33-mer), Synthetic construct (synthetic) C: Product RNA (14-mer), Synthetic construct (synthetic) L7WS61 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases ✘

Interologs

Total number of interologs for this interface: 10

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4K4Z_E_F,G 5Y6Z_A_B,C 0.90 0.98 0.73 0.87 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5Y6Z_A_B,C 6KWQ_A_B,C 0.94 0.99 0.55 0.93 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5Y6Z_A_B,C 6LSF_A_B,C 0.93 0.98 0.51 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5Y6Z_A_B,C 6LSG_A_B,C 0.87 0.97 0.85 0.8 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 5Y6Z_A_B,C 0.88 0.98 0.8 0.87 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 5Y6Z_A_B,C 0.97 0.98 0.61 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3OL9_A_B,C 5Y6Z_A_B,C 0.91 0.98 0.68 0.87 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3AVX_A_G,T 5Y6Z_A_B,C 0.52 0.61 2.95 0.1 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5Y6Z_A_B,C 7BV2_A_T 0.59 0.8 1.4 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
5Y6Z_A_B,C 7AAP_A_T 0.65 0.8 1.76 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare