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All interfaces > All interologs > Interface groups > group130 > 6KWQ_A_B,C

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Licorice
Surface

RNA

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Licorice
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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

6KWQ_A
6KWQ_B,C
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:18 [ASN] B:581 [G] 2.97 base:SC 76.06
A:18 [ASN] B:582 [G] 4.04 B:597 [C] base/AA stacks 76.06
A:18 [ASN] B:598 [A] 2.89 sugar:BB 76.06
A:19 [GLY] B:581 [G] 4.42 75.34
A:19 [GLY] B:598 [A] 3.73 75.34
A:19 [GLY] B:599 [G] 4.51 75.34
A:20 [PRO] B:598 [A] 3.31 67.14
A:20 [PRO] B:599 [G] 3.6 67.14
A:21 [THR] B:581 [G] 3.66 81.91
A:21 [THR] B:598 [A] 4.48 81.91
A:24 [LYS] B:598 [A] 3.59 56.93
A:24 [LYS] B:599 [G] 3.41 56.93
A:43 [LEU] B:581 [G] 4.06 93.46
A:44 [HIS] B:581 [G] 3.48 sugar:SC base/AA stacks 81.85
A:45 [SER] B:581 [G] 2.78 base:SC, base:BB 11.3
A:46 [LYS] B:581 [G] 2.54 42.17
A:54 [PHE] B:581 [G] 3.99 53.52
A:55 [GLU] B:581 [G] 4.65 69.4
A:106 [ASN] B:603 [U] 4.39 C:1310 [A] 57.38
A:107 [LEU] B:602 [C] 4.6 C:1311 [G] 82.33
A:107 [LEU] B:603 [U] 3.86 C:1310 [A] 82.33
A:108 [GLU] B:602 [C] 4.89 C:1311 [G] 77.44
A:108 [GLU] B:603 [U] 3.03 C:1310 [A] 77.44
A:110 [ILE] B:601 [U] 4.69 C:1312 [A] 79.95
A:110 [ILE] B:602 [C] 4.86 C:1311 [G] 79.95
A:111 [ASP] B:601 [U] 4.07 C:1312 [A] 94.01
A:113 [HIS] B:600 [G] 4.88 59.35
A:113 [HIS] C:1306 [C] 3.79 B:607 [G] 59.35
A:113 [HIS] C:1307 [G] 2.57 B:606 [C] 59.35
A:114 [THR] B:600 [G] 3.3 94.38
A:114 [THR] B:601 [U] 2.7 C:1312 [A] 94.38
A:115 [SER] B:598 [A] 4.85 96.52
A:115 [SER] B:599 [G] 2.53 96.52
A:115 [SER] B:600 [G] 2.59 96.52
A:115 [SER] B:601 [U] 4.41 C:1312 [A] 96.52
A:121 [SER] B:598 [A] 4.46 62.73
A:121 [SER] B:599 [G] 3.43 62.73
A:126 [LYS] B:598 [A] 3.3 75.61
A:126 [LYS] B:599 [G] 3.51 75.61
A:127 [LYS] B:600 [G] 4.27 96.76
A:127 [LYS] B:601 [U] 2.77 C:1312 [A] 96.76
A:128 [ARG] C:1305 [C] 4.96 B:608 [G] 57.51
A:128 [ARG] C:1306 [C] 2.67 B:607 [G] 57.51
A:133 [PRO] C:1305 [C] 4.08 B:608 [G] 0.82
A:157 [TYR] B:598 [A] 4.67 77.23
A:157 [TYR] B:599 [G] 3.39 77.23
A:159 [LYS] B:600 [G] 2.89 base:SC 98.89
A:159 [LYS] C:1312 [A] 4.96 B:601 [U] 98.89
A:160 [ASP] B:599 [G] 3.87 98.95
A:176 [ILE] B:599 [G] 3.58 92.93
A:176 [ILE] B:600 [G] 3.28 92.93
A:177 [GLU] B:600 [G] 3.76 sugar:BB 93.69
A:178 [ALA] B:600 [G] 3.36 86.02
A:179 [SER] B:600 [G] 3.21 sugar:BB 85.17
A:179 [SER] B:601 [U] 4.61 C:1312 [A] 85.17
A:184 [SER] B:601 [U] 4.08 C:1312 [A] 81.24
A:184 [SER] B:602 [C] 4.86 C:1311 [G] 81.24
A:188 [ARG] B:601 [U] 4.75 C:1312 [A] 96.31
A:188 [ARG] B:602 [C] 2.6 C:1311 [G] 96.31
A:195 [TYR] B:602 [C] 4.4 C:1311 [G] 63.24
A:199 [HIS] B:602 [C] 3.5 C:1311 [G] 83.84
A:199 [HIS] B:603 [U] 3.42 C:1310 [A] 83.84
A:209 [ALA] B:603 [U] 4.85 C:1310 [A] 98.68
A:210 [VAL] B:602 [C] 3.97 C:1311 [G] 93.69
A:210 [VAL] B:603 [U] 3.82 C:1310 [A] 93.69
A:211 [GLY] B:603 [U] 2.86 C:1310 [A] sugar:BB 98.26
A:211 [GLY] B:604 [C] 3.49 C:1309 [G] 98.26
A:212 [CYS] B:603 [U] 3.82 C:1310 [A] 84.04
A:212 [CYS] B:604 [C] 3.15 C:1309 [G] 84.04
A:213 [ASN] B:604 [C] 3.22 C:1309 [G] 79.33
A:213 [ASN] B:605 [U] 3.48 C:1308 [A] 79.33
A:214 [PRO] B:604 [C] 3.73 C:1309 [G] 98.42
A:276 [TYR] B:581 [G] 4.27 66.21
A:277 [ARG] B:581 [G] 2.88 sugar:SC base/AA stacks 50.28
A:289 [SER] B:600 [G] 2.25 base:BB 99.0
A:289 [SER] B:601 [U] 4.51 C:1312 [A] 99.0
A:290 [GLY] B:600 [G] 2.6 sugar:BB 98.76
A:290 [GLY] B:601 [U] 2.95 C:1312 [A] 98.76
A:291 [CYS] B:600 [G] 4.68 82.65
A:291 [CYS] B:601 [U] 2.74 C:1312 [A] sugar:BB 82.65
A:292 [SER] B:601 [U] 3.38 C:1312 [A] 90.16
A:292 [SER] B:602 [C] 2.91 C:1311 [G] 90.16
A:293 [GLY] B:601 [U] 3.23 C:1312 [A] sugar:BB 88.12
A:293 [GLY] B:602 [C] 4.62 C:1311 [G] 88.12
A:294 [THR] B:600 [G] 4.73 99.0
A:294 [THR] B:601 [U] 3.73 C:1312 [A] 99.0
A:295 [SER] B:601 [U] 4.99 C:1312 [A] 96.49
A:295 [SER] B:602 [C] 3.93 C:1311 [G] 96.49
A:295 [SER] C:1312 [A] 4.28 B:601 [U] 96.49
A:327 [TYR] B:602 [C] 4.08 C:1311 [G] 98.68
A:327 [TYR] B:603 [U] 3.29 C:1310 [A] 98.68
A:327 [TYR] C:1311 [G] 3.08 B:602 [C] base:SC 98.68
A:327 [TYR] C:1312 [A] 2.82 B:601 [U] 98.68
A:328 [GLY] C:1312 [A] 3.34 B:601 [U] 98.74
A:329 [ASP] C:1312 [A] 2.82 B:601 [U] 98.95
A:330 [ASP] C:1312 [A] 3.53 B:601 [U] 98.95
A:375 [LEU] C:1311 [G] 3.4 B:602 [C] 98.74
A:375 [LEU] C:1312 [A] 4.0 B:601 [U] 98.74
A:376 [LYS] C:1311 [G] 2.73 B:602 [C] 98.66
A:376 [LYS] C:1312 [A] 3.56 B:601 [U] 98.66
A:377 [ARG] C:1310 [A] 4.08 B:603 [U] 98.79
A:377 [ARG] C:1311 [G] 3.93 B:602 [C] sugar:SC 98.79
A:393 [MET] C:1310 [A] 3.45 B:603 [U] 84.43
A:393 [MET] C:1311 [G] 3.98 B:602 [C] 84.43
A:397 [GLU] C:1311 [G] 4.09 B:602 [C] 79.48
A:401 [SER] C:1309 [G] 3.46 B:604 [C] 87.65
A:401 [SER] C:1310 [A] 2.6 B:603 [U] 87.65
A:406 [LYS] C:1309 [G] 2.92 B:604 [C] 85.31
A:410 [ASN] C:1307 [G] 3.86 B:606 [C] 59.57
A:410 [ASN] C:1308 [A] 3.26 B:605 [U] 59.57
A:410 [ASN] C:1309 [G] 4.63 B:604 [C] 59.57
A:413 [ASP] B:607 [G] 3.42 C:1306 [C] sugar:SC 74.42
A:413 [ASP] C:1307 [G] 3.09 B:606 [C] base:SC 74.42
A:413 [ASP] C:1308 [A] 3.73 B:605 [U] 74.42
A:413 [ASP] C:1309 [G] 4.94 B:604 [C] 74.42
A:414 [HIS] C:1308 [A] 3.71 B:605 [U] 83.63
A:414 [HIS] C:1309 [G] 3.55 B:604 [C] 83.63
A:414 [HIS] C:1310 [A] 4.45 B:603 [U] 83.63
A:416 [ARG] B:606 [C] 2.85 C:1307 [G] sugar:SC 16.45
A:416 [ARG] B:607 [G] 3.26 C:1306 [C] 16.45
A:417 [SER] B:605 [U] 4.85 C:1308 [A] 94.75
A:417 [SER] B:606 [C] 4.21 C:1307 [G] 94.75
A:417 [SER] C:1308 [A] 4.47 B:605 [U] 94.75
A:417 [SER] C:1309 [G] 3.66 B:604 [C] 94.75
A:418 [LEU] C:1309 [G] 3.88 B:604 [C] 84.13
A:418 [LEU] C:1310 [A] 4.24 B:603 [U] 84.13
A:420 [LEU] B:605 [U] 3.64 C:1308 [A] 7.1
A:420 [LEU] B:606 [C] 3.41 C:1307 [G] 7.1
A:421 [LEU] C:1309 [G] 4.87 B:604 [C] 94.27
A:421 [LEU] C:1310 [A] 3.95 B:603 [U] 94.27

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group130 6KWQ_A_B,C A: RNA-dependent RNA polymerase, Enterovirus a71 (genetically engineered) B: RNA (31-mer), Synthetic construct (synthetic) C: Synthetic construct (synthetic) M4QLY4 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases ✘

Interologs

Total number of interologs for this interface: 9

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4K4Z_E_F,G 6KWQ_A_B,C 0.92 0.98 0.55 0.77 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5Y6Z_A_B,C 6KWQ_A_B,C 0.94 0.99 0.55 0.93 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 6KWQ_A_B,C 0.92 0.98 0.61 0.79 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 6KWQ_A_B,C 0.97 1.0 0.33 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3OL9_A_B,C 6KWQ_A_B,C 0.92 0.98 0.63 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
6KWQ_A_B,C 6LSG_A_B,C 0.83 0.99 0.64 0.8 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
6KWQ_A_B,C 7AAP_A_T 0.68 0.77 1.65 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
6KWQ_A_B,C 7BV2_A_T 0.63 0.78 1.32 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
6KWQ_A_B,C 6LSF_A_B,C 0.93 0.99 0.54 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare