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All interfaces > All interologs > Interface groups > group130 > 6LSF_A_B,C

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Licorice
Surface

RNA

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Licorice
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Chain
Chain (with hetatm)
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Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

6LSF_A
6LSF_B,C
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:19 [GLY] B:599 [C] 4.99 68.61
A:20 [PRO] B:599 [C] 3.56 68.7
A:24 [LYS] B:599 [C] 3.69 base:SC 57.52
A:106 [ASN] B:603 [U] 4.87 C:1307 [A] 56.03
A:107 [LEU] B:603 [U] 4.76 C:1307 [A] 83.75
A:108 [GLU] B:603 [U] 3.66 C:1307 [A] 79.62
A:109 [ALA] B:602 [G] 4.93 C:1308 [C] 75.29
A:110 [ILE] B:601 [G] 4.76 C:1309 [C] 82.76
A:111 [ASP] B:601 [G] 4.21 C:1309 [C] 93.44
A:111 [ASP] B:602 [G] 4.64 C:1308 [C] 93.44
A:113 [HIS] C:1303 [A] 3.58 B:607 [U] 59.33
A:113 [HIS] C:1304 [G] 2.79 B:606 [C] 59.33
A:114 [THR] B:599 [C] 4.54 94.46
A:114 [THR] B:600 [A] 2.81 94.46
A:114 [THR] B:601 [G] 2.93 C:1309 [C] 94.46
A:115 [SER] B:599 [C] 3.17 96.17
A:115 [SER] B:600 [A] 2.96 96.17
A:115 [SER] B:601 [G] 4.43 C:1309 [C] 96.17
A:121 [SER] B:599 [C] 4.36 58.92
A:127 [LYS] B:600 [A] 4.24 97.45
A:127 [LYS] B:601 [G] 2.75 C:1309 [C] 97.45
A:133 [SER] C:1301 [A] 4.78 0.56
A:133 [SER] C:1302 [G] 2.71 0.56
A:157 [TYR] B:599 [C] 3.51 79.07
A:157 [TYR] B:600 [A] 4.67 79.07
A:159 [LYS] B:600 [A] 3.07 98.89
A:159 [LYS] C:1309 [C] 4.8 B:601 [G] 98.89
A:176 [ILE] B:599 [C] 4.1 91.09
A:176 [ILE] B:600 [A] 3.19 91.09
A:177 [GLU] B:600 [A] 4.36 93.95
A:178 [ALA] B:600 [A] 3.09 87.09
A:179 [SER] B:600 [A] 3.19 sugar:BB 85.16
A:184 [SER] B:601 [G] 4.35 C:1309 [C] 81.44
A:188 [ARG] B:601 [G] 4.91 C:1309 [C] 96.35
A:188 [ARG] B:602 [G] 2.72 C:1308 [C] 96.35
A:199 [HIS] B:602 [G] 3.71 C:1308 [C] 82.22
A:199 [HIS] B:603 [U] 3.18 C:1307 [A] 82.22
A:209 [ALA] B:603 [U] 4.75 C:1307 [A] 98.23
A:210 [VAL] B:602 [G] 3.98 C:1308 [C] 94.8
A:210 [VAL] B:603 [U] 3.73 C:1307 [A] 94.8
A:211 [GLY] B:603 [U] 2.82 C:1307 [A] sugar:BB 98.25
A:211 [GLY] B:604 [C] 3.49 C:1306 [G] 98.25
A:212 [CYS] B:603 [U] 3.75 C:1307 [A] 83.05
A:212 [CYS] B:604 [C] 3.14 C:1306 [G] 83.05
A:213 [ASN] B:604 [C] 3.5 C:1306 [G] 80.09
A:213 [ASN] B:605 [U] 3.49 80.09
A:214 [PRO] B:604 [C] 4.12 C:1306 [G] 97.5
A:289 [SER] B:600 [A] 3.45 99.0
A:289 [SER] B:601 [G] 4.34 C:1309 [C] 99.0
A:290 [GLY] B:600 [A] 2.68 sugar:BB 98.76
A:290 [GLY] B:601 [G] 2.99 C:1309 [C] 98.76
A:291 [MET] B:600 [A] 4.71 78.83
A:291 [MET] B:601 [G] 2.38 C:1309 [C] sugar:BB 78.83
A:292 [SER] B:601 [G] 3.3 C:1309 [C] 89.11
A:292 [SER] B:602 [G] 4.23 C:1308 [C] 89.11
A:293 [GLY] B:601 [G] 3.49 C:1309 [C] sugar:BB 87.63
A:294 [THR] B:601 [G] 4.21 C:1309 [C] 98.97
A:295 [SER] B:601 [G] 2.94 C:1309 [C] base:SC 95.98
A:295 [SER] B:602 [G] 4.29 C:1308 [C] 95.98
A:295 [SER] C:1309 [C] 3.36 B:601 [G] base:SC 95.98
A:327 [TYR] B:602 [G] 3.16 C:1308 [C] base:SC 98.68
A:327 [TYR] B:603 [U] 3.22 C:1307 [A] 98.68
A:327 [TYR] C:1308 [C] 4.81 B:602 [G] 98.68
A:327 [TYR] C:1309 [C] 2.39 B:601 [G] 98.68
A:328 [GLY] C:1309 [C] 3.68 B:601 [G] 98.73
A:329 [ASP] C:1309 [C] 4.03 B:601 [G] 98.92
A:330 [ASP] C:1309 [C] 4.08 B:601 [G] 98.92
A:375 [LEU] C:1308 [C] 3.2 B:602 [G] 98.71
A:375 [LEU] C:1309 [C] 4.37 B:601 [G] 98.71
A:376 [LYS] C:1308 [C] 2.73 B:602 [G] 98.63
A:376 [LYS] C:1309 [C] 3.73 B:601 [G] 98.63
A:377 [ARG] C:1307 [A] 3.72 B:603 [U] 98.73
A:377 [ARG] C:1308 [C] 3.73 B:602 [G] sugar:SC 98.73
A:393 [MET] C:1307 [A] 3.45 B:603 [U] 85.47
A:393 [MET] C:1308 [C] 4.11 B:602 [G] 85.47
A:397 [GLU] C:1308 [C] 4.17 B:602 [G] 79.74
A:401 [SER] C:1306 [G] 3.72 B:604 [C] 86.19
A:401 [SER] C:1307 [A] 2.79 B:603 [U] 86.19
A:405 [THR] C:1306 [G] 4.79 B:604 [C] 60.88
A:406 [LYS] C:1306 [G] 4.15 B:604 [C] 84.92
A:407 [ASP] C:1306 [G] 4.65 B:604 [C] 56.62
A:410 [ASN] C:1304 [G] 3.89 B:606 [C] 58.2
A:410 [ASN] C:1305 [A] 3.14 58.2
A:413 [ASP] B:606 [C] 4.78 C:1304 [G] 71.8
A:413 [ASP] B:607 [U] 4.48 C:1303 [A] 71.8
A:413 [ASP] C:1304 [G] 2.58 B:606 [C] base:SC 71.8
A:413 [ASP] C:1305 [A] 3.74 71.8
A:413 [ASP] C:1306 [G] 4.98 B:604 [C] 71.8
A:414 [HIS] C:1305 [A] 4.02 81.7
A:414 [HIS] C:1306 [G] 3.74 B:604 [C] 81.7
A:414 [HIS] C:1307 [A] 4.36 B:603 [U] 81.7
A:416 [ARG] B:606 [C] 4.22 C:1304 [G] 32.76
A:417 [SER] C:1305 [A] 4.89 93.39
A:417 [SER] C:1306 [G] 3.5 B:604 [C] 93.39
A:418 [LEU] C:1306 [G] 4.49 B:604 [C] 81.87
A:418 [LEU] C:1307 [A] 4.38 B:603 [U] 81.87
A:420 [LEU] B:605 [U] 3.58 2.14
A:420 [LEU] B:606 [C] 4.5 C:1304 [G] 2.14
A:421 [LEU] C:1307 [A] 3.69 B:603 [U] 93.95

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group130 6LSF_A_B,C A: Genome polyprotein, Human enterovirus 71 (genetically engineered) B: RNA (35-mer), Synthetic construct (synthetic) C: Synthetic construct (synthetic) E5RPG3 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases ✘

Interologs

Total number of interologs for this interface: 10

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4K4Z_E_F,G 6LSF_A_B,C 0.87 0.99 0.7 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5Y6Z_A_B,C 6LSF_A_B,C 0.93 0.98 0.51 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 6LSF_A_B,C 0.87 0.98 0.74 0.5 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
5F8H_A_B,C 6LSF_A_B,C 0.94 0.99 0.49 0.65 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3OL9_A_B,C 6LSF_A_B,C 0.90 0.98 0.62 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3AVX_A_G,T 6LSF_A_B,C 0.58 0.61 2.84 0.1 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
6KWQ_A_B,C 6LSF_A_B,C 0.93 0.99 0.54 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
6LSF_A_B,C 6LSG_A_B,C 0.86 0.99 0.74 0.67 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
6LSF_A_B,C 7AAP_A_T 0.69 0.8 1.7 0.09 Adenylyl and guanylyl cyclase catalytic domain-like compare
6LSF_A_B,C 7BV2_A_T 0.69 0.8 1.31 0.1 Adenylyl and guanylyl cyclase catalytic domain-like compare