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All interfaces > All interologs > Interface groups > group130 > 7AAP_A_T

Interface analysis

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Protein

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Licorice
Surface

RNA

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Licorice
Surface

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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

7AAP_A
7AAP_T
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:408 [GLN] T:8 [U] 4.71 95.22
A:496 [ASN] T:12 [U] 4.26 P:19 [A] 75.02
A:496 [ASN] T:13 [A] 4.46 P:18 [U] 75.02
A:497 [ASN] T:11 [A] 4.56 P:20 [U] 98.3
A:500 [LYS] T:10 [C] 4.05 94.72
A:500 [LYS] T:11 [A] 2.65 P:20 [U] 94.72
A:501 [SER] T:9 [U] 2.59 96.68
A:501 [SER] T:10 [C] 3.55 96.68
A:501 [SER] T:11 [A] 4.89 P:20 [U] 96.68
A:507 [ASN] T:8 [U] 4.43 98.3
A:507 [ASN] T:9 [U] 3.27 98.3
A:511 [LYS] T:9 [U] 4.99 92.37
A:541 [GLN] T:8 [U] 4.68 92.41
A:541 [GLN] T:9 [U] 3.89 92.41
A:543 [ASN] T:8 [U] 2.91 sugar:SC 89.31
A:543 [ASN] T:9 [U] 3.41 89.31
A:544 [LEU] T:9 [U] 5.0 83.79
A:545 [LYS] T:10 [C] 4.03 98.31
A:557 [VAL] T:9 [U] 4.94 91.37
A:557 [VAL] T:10 [C] 3.45 91.37
A:558 [ALA] T:10 [C] 3.65 sugar:BB 91.79
A:559 [GLY] T:10 [C] 4.01 90.93
A:560 [VAL] T:10 [C] 4.19 95.08
A:569 [ARG] T:11 [A] 4.17 P:20 [U] 98.5
A:569 [ARG] T:12 [U] 3.29 P:19 [A] 98.5
A:577 [LYS] T:12 [U] 4.58 P:19 [A] 94.28
A:577 [LYS] T:13 [A] 2.94 P:18 [U] 94.28
A:580 [ALA] T:13 [A] 3.79 P:18 [U] 83.57
A:580 [ALA] T:14 [A] 4.82 P:17 [U] 83.57
A:583 [ARG] T:14 [A] 4.92 P:17 [U] 94.75
A:589 [ILE] T:12 [U] 4.39 P:19 [A] 98.72
A:589 [ILE] T:13 [A] 4.52 P:18 [U] 98.72
A:590 [GLY] T:13 [A] 3.08 P:18 [U] 97.87
A:590 [GLY] T:14 [A] 3.3 P:17 [U] 97.87
A:591 [THR] T:13 [A] 4.46 P:18 [U] 94.22
A:591 [THR] T:14 [A] 4.74 P:17 [U] 94.22
A:592 [SER] T:14 [A] 2.66 P:17 [U] sugar:SC 90.03
A:592 [SER] T:15 [C] 3.82 P:16 [G] 90.03
A:593 [LYS] T:14 [A] 4.47 P:17 [U] 98.35
A:594 [PHE] T:14 [A] 3.96 P:17 [U] 92.48
A:594 [PHE] T:15 [C] 3.65 P:16 [G] 92.48
A:595 [TYR] T:15 [C] 3.86 P:16 [G] 85.54
A:595 [TYR] T:16 [U] 2.67 P:15 [A] 85.54
A:682 [SER] T:10 [C] 3.55 95.29
A:682 [SER] T:11 [A] 3.88 P:20 [U] 95.29
A:683 [GLY] T:10 [C] 3.25 sugar:BB 96.43
A:683 [GLY] T:11 [A] 3.11 P:20 [U] 96.43
A:684 [ASP] T:11 [A] 2.75 P:20 [U] sugar:BB 96.07
A:685 [ALA] T:11 [A] 3.24 P:20 [U] 92.08
A:685 [ALA] T:12 [U] 3.86 P:19 [A] 92.08
A:686 [THR] T:11 [A] 4.51 P:20 [U] 89.33
A:687 [THR] T:11 [A] 4.92 P:20 [U] 93.69
A:688 [ALA] T:12 [U] 4.92 P:19 [A] 93.22
A:689 [TYR] T:12 [U] 3.11 P:19 [A] sugar:SC 82.38
A:689 [TYR] T:13 [A] 3.73 P:18 [U] 82.38
A:857 [GLU] T:17 [U] 3.34 P:14 [A] 97.78
A:860 [VAL] T:16 [U] 3.8 P:15 [A] 96.06
A:861 [SER] T:16 [U] 4.3 P:15 [A] 94.65
A:864 [ILE] T:15 [C] 4.52 P:16 [G] 98.24
A:864 [ILE] T:16 [U] 4.05 P:15 [A] 98.24
A:914 [ARG] T:17 [U] 3.31 P:14 [A] 82.25
A:914 [ARG] T:18 [A] 4.8 P:13 [U] 82.25
A:915 [TYR] T:17 [U] 4.09 P:14 [A] 83.83
A:915 [TYR] T:18 [A] 4.7 P:13 [U] 83.83
A:920 [PHE] T:16 [U] 4.13 P:15 [A] 96.98
A:920 [PHE] T:17 [U] 4.13 P:14 [A] 96.98
A:924 [MET] T:15 [C] 3.3 P:16 [G] 73.75
A:924 [MET] T:16 [U] 3.68 P:15 [A] 73.75

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group130 7AAP_A_T A: Non-structural protein 12, Severe acute respiratory syndrome coronavirus 2 (genetically engineered) T: Severe acute respiratory syndrome coronavirus 2 (synthetic) P0DTD1 Adenylyl and guanylyl cyclase catalytic domain-like ✘

Interologs

Total number of interologs for this interface: 9

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
7AAP_A_T 7BV2_A_T 0.96 0.99 0.42 0.9 Adenylyl and guanylyl cyclase catalytic domain-like compare
5F8H_A_B,C 7AAP_A_T 0.70 0.8 1.58 0.09 Adenylyl and guanylyl cyclase catalytic domain-like compare
6KWQ_A_B,C 7AAP_A_T 0.68 0.77 1.65 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
6LSF_A_B,C 7AAP_A_T 0.69 0.8 1.7 0.09 Adenylyl and guanylyl cyclase catalytic domain-like compare
6LSG_A_B,C 7AAP_A_T 0.59 0.8 1.73 0.09 Adenylyl and guanylyl cyclase catalytic domain-like compare
5Y6Z_A_B,C 7AAP_A_T 0.65 0.8 1.76 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
4K4Z_E_F,G 7AAP_A_T 0.61 0.79 1.77 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
3OL9_A_B,C 7AAP_A_T 0.68 0.79 1.81 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
4K4S_A_B,C 7AAP_A_T 0.66 0.79 1.85 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare