Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
2YKG_A
|
2YKG_C,D
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:298 [ASN] | D:18 [C] | 3.24 | C:3 [G] | 81.47 | ||
A:298 [ASN] | D:19 [G] | 3.27 | C:2 [C] | 81.47 | ||
A:299 [GLN] | D:18 [C] | 3.63 | C:3 [G] | 76.35 | ||
A:299 [GLN] | D:19 [G] | 3.6 | C:2 [C] | 76.35 | ||
A:300 [ILE] | D:18 [C] | 4.57 | C:3 [G] | 78.26 | ||
A:300 [ILE] | D:19 [G] | 2.75 | C:2 [C] | 78.26 | ||
A:300 [ILE] | D:20 [C] | 3.81 | C:1 [G] | 78.26 | ||
A:301 [PRO] | D:19 [G] | 4.14 | C:2 [C] | 71.21 | ||
A:325 [SER] | D:20 [C] | 3.61 | C:1 [G] | 82.4 | ||
A:326 [GLY] | D:19 [G] | 4.99 | C:2 [C] | 90.8 | ||
A:326 [GLY] | D:20 [C] | 2.77 | C:1 [G] | 90.8 | ||
A:347 [THR] | D:19 [G] | 3.97 | C:2 [C] | 98.76 | ||
A:347 [THR] | D:20 [C] | 2.77 | C:1 [G] | 98.76 | ||
A:349 [GLN] | C:3 [G] | 4.73 | D:18 [C] | 93.8 | ||
A:349 [GLN] | D:19 [G] | 3.66 | C:2 [C] | 93.8 | ||
A:349 [GLN] | D:20 [C] | 3.83 | C:1 [G] | 93.8 | ||
A:350 [ILE] | D:20 [C] | 3.72 | C:1 [G] | 88.96 | ||
A:353 [ASN] | D:20 [C] | 3.36 | C:1 [G] | 94.1 | ||
A:376 [ASN] | C:5 [G] | 4.33 | D:16 [C] | 92.85 | ||
A:378 [SER] | C:5 [G] | 4.84 | D:16 [C] | 45.2 | ||
A:379 [LYS] | C:5 [G] | 3.19 | D:16 [C] | 74.83 | ||
A:379 [LYS] | C:6 [C] | 2.89 | D:15 [G] | 74.83 | ||
A:380 [GLN] | C:4 [C] | 3.44 | D:17 [G] | 57.04 | ||
A:380 [GLN] | C:5 [G] | 2.93 | D:16 [C] | 57.04 | ||
A:381 [HIS] | C:4 [C] | 3.44 | D:17 [G] | 79.34 | ||
A:381 [HIS] | C:5 [G] | 4.13 | D:16 [C] | 79.34 | ||
A:382 [PRO] | C:4 [C] | 3.71 | D:17 [G] | 83.61 | ||
A:498 [GLN] | D:13 [G] | 4.82 | C:8 [C] | 36.14 | ||
A:498 [GLN] | D:14 [C] | 3.08 | C:7 [G] | 36.14 | ||
A:499 [ILE] | D:14 [C] | 3.3 | C:7 [G] | 52.09 | ||
A:499 [ILE] | D:15 [G] | 3.67 | C:6 [C] | 52.09 | ||
A:500 [GLN] | D:14 [C] | 4.95 | C:7 [G] | 4.72 | ||
A:508 [LYS] | D:14 [C] | 4.4 | C:7 [G] | 24.06 | ||
A:511 [GLN] | D:15 [G] | 3.27 | C:6 [C] | sugar:SC | 83.3 | |
A:511 [GLN] | D:16 [C] | 4.23 | C:5 [G] | 83.3 | ||
A:515 [THR] | D:15 [G] | 4.0 | C:6 [C] | 24.09 | ||
A:750 [LYS] | C:8 [C] | 3.3 | D:13 [G] | 82.0 | ||
A:829 [CYS] | C:1 [G] | 4.59 | D:20 [C] | 57.73 | ||
A:829 [CYS] | C:2 [C] | 3.35 | D:19 [G] | 57.73 | ||
A:830 [HIS] | C:1 [G] | 2.92 | D:20 [C] | sugar:SC | 86.88 | |
A:830 [HIS] | C:2 [C] | 3.36 | D:19 [G] | 86.88 | ||
A:831 [TYR] | C:1 [G] | 4.88 | D:20 [C] | 87.09 | ||
A:853 [PHE] | C:1 [G] | 3.27 | D:20 [C] | base/AA stacks | 2.02 | |
A:853 [PHE] | D:20 [C] | 3.35 | C:1 [G] | base/AA stacks | 2.02 | |
A:854 [SER] | D:20 [C] | 2.43 | C:1 [G] | sugar:SC | 46.45 | |
A:856 [PHE] | C:1 [G] | 3.59 | D:20 [C] | 37.5 | ||
A:858 [LYS] | C:1 [G] | 4.61 | D:20 [C] | 46.34 | ||
A:874 [GLY] | C:1 [G] | 3.58 | D:20 [C] | 95.2 | ||
A:875 [ILE] | C:1 [G] | 3.3 | D:20 [C] | 69.17 | ||
A:886 [VAL] | C:1 [G] | 3.34 | D:20 [C] | 68.43 | ||
A:887 [ILE] | C:1 [G] | 3.82 | D:20 [C] | 72.63 | ||
A:887 [ILE] | C:2 [C] | 4.39 | D:19 [G] | 72.63 | ||
A:888 [LYS] | C:1 [G] | 3.87 | D:20 [C] | 79.08 | ||
A:888 [LYS] | C:2 [C] | 3.69 | D:19 [G] | 79.08 | ||
A:889 [ILE] | C:2 [C] | 4.22 | D:19 [G] | 87.03 | ||
A:890 [GLU] | D:14 [C] | 4.84 | C:7 [G] | 44.76 | ||
A:906 [SER] | D:13 [G] | 3.15 | C:8 [C] | 67.48 | ||
A:907 [LYS] | C:3 [G] | 4.5 | D:18 [C] | 82.89 | ||
A:907 [LYS] | C:4 [C] | 4.71 | D:17 [G] | 82.89 | ||
A:908 [TRP] | C:1 [G] | 4.71 | D:20 [C] | 94.13 | ||
A:908 [TRP] | C:2 [C] | 3.3 | D:19 [G] | 94.13 | ||
A:909 [LYS] | C:3 [G] | 3.83 | D:18 [C] | 72.14 | ||
A:910 [ASP] | D:12 [C] | 4.91 | C:9 [G] | 64.76 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group135 | 2YKG_A_C,D | A: Probable atp-dependent RNA helicase ddx58, Homo sapiens (natural) C: Homo sapiens (natural) D: Homo sapiens (natural) | O95786 | P-loop containing nucleoside triphosphate hydrolases & Helical bundle in Hef helicase & Mss4-like | ✘ |
Interologs
Total number of interologs for this interface: 5
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
2YKG_A_C,D | 3OG8_A_C,D | 0.81 | 0.82 | 0.73 | 0.3 | Mss4-like | compare | |
2YKG_A_C,D | 5JB2_A_X,Y | 0.60 | 0.72 | 2.5 | 0.33 | P-loop containing nucleoside triphosphate hydrolases & Helical bundle in Hef helicase & Mss4-like | compare | |
2YKG_A_C,D | 5JAJ_A_X,Y | 0.60 | 0.71 | 2.58 | 0.33 | P-loop containing nucleoside triphosphate hydrolases & Helical bundle in Hef helicase & Mss4-like | compare | |
2YKG_A_C,D | 3ZD7_A_C,D | 0.82 | 0.91 | 2.9 | 0.73 | P-loop containing nucleoside triphosphate hydrolases & Helical bundle in Hef helicase & Mss4-like | compare | |
2YKG_A_C,D | 5JBG_A_X | 0.54 | 0.71 | 3.07 | 0.31 | P-loop containing nucleoside triphosphate hydrolases & Helical bundle in Hef helicase & Mss4-like | compare |