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All interfaces > All interologs > Interface groups > group140 > 4F3T_A_R vs 5I4A_A_B

Interface analysis


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Common contacts -

4F3T_A
4F3T_R
5I4A_A
5I4A_B
Conserved?
A:566 [LYS] R:1 [U] A:418 [LYS] B:1 [U]
A:566 [LYS] R:2 [A] A:418 [LYS] B:2 [A]
A:566 [LYS] R:3 [A] A:418 [LYS] B:3 [U]
A:797 [VAL] R:4 [A] A:614 [TYR] B:4 [A]
A:562 [ASN] R:2 [A] A:414 [SER] B:2 [A]
A:793 [CYS] R:3 [A] A:609 [THR] B:3 [U]
A:526 [THR] R:1 [U] A:380 [ILE] B:1 [U]
A:522 [LEU] R:1 [U] A:376 [LEU] B:1 [U]
A:563 [LEU] R:2 [A] A:415 [TYR] B:2 [A]
A:798 [SER] R:4 [A] A:615 [LYS] B:4 [A]
A:558 [GLN] R:2 [A] A:410 [PHE] B:2 [A]
A:559 [THR] R:2 [A] A:411 [ILE] B:2 [A]
A:804 [TYR] R:4 [A] A:621 [HIS] B:4 [A]
A:815 [TYR] R:1 [U] A:632 [GLU] B:1 [U]
A:756 [ILE] R:4 [A] A:573 [PHE] B:4 [A]
A:547 [VAL] R:1 [U] A:399 [ILE] B:1 [U]
A:547 [VAL] R:2 [A] A:399 [ILE] B:2 [A]
A:529 [TYR] R:1 [U] A:383 [ILE] B:1 [U]
A:792 [ARG] R:3 [A] A:608 [SER] B:3 [U]
A:792 [ARG] R:4 [A] A:608 [SER] B:4 [A]
A:795 [ARG] R:3 [A] A:612 [THR] B:3 [U]
A:795 [ARG] R:4 [A] A:612 [THR] B:4 [A]
A:551 [ASN] R:2 [A] A:403 [LYS] B:2 [A]
A:546 [CYS] R:1 [U] A:398 [PRO] B:1 [U]
A:546 [CYS] R:2 [A] A:398 [PRO] B:2 [A]
A:548 [GLN] R:1 [U] A:400 [LEU] B:1 [U]
A:548 [GLN] R:2 [A] A:400 [LEU] B:2 [A]
A:525 [LYS] R:1 [U] A:379 [TYR] B:1 [U]
A:524 [GLY] R:1 [U] A:378 [LYS] B:1 [U]
A:710 [ARG] R:9 [U] A:545 [ASN] B:9 [C] ❌ 5I4A_A_B
A:562 [ASN] R:3 [A] A:414 [SER] B:3 [U] ❌ 5I4A_A_B
A:793 [CYS] R:4 [A] A:609 [THR] B:4 [A] ❌ 5I4A_A_B
A:220 [SER] R:8 [C] A:148 [LYS] B:8 [C] ❌ 5I4A_A_B
A:220 [SER] R:9 [U] A:148 [LYS] B:9 [C] ❌ 4F3T_A_R
A:525 [LYS] R:4 [A] A:379 [TYR] B:4 [A] ❌ 4F3T_A_R
A:551 [ASN] R:3 [A] A:403 [LYS] B:3 [U] ❌ 4F3T_A_R
A:757 [GLN] R:4 [A] A:574 [LEU] B:4 [A] ❌ 4F3T_A_R
A:793 [CYS] R:2 [A] A:609 [THR] B:2 [A] ❌ 4F3T_A_R
A:635 [ARG] R:9 [U] A:480 [LEU] B:9 [C] ❌ 5I4A_A:480 no longer at interface
A:812 [ARG] R:1 [U] A:629 [THR] B:1 [U] ❌ 5I4A_A:629 no longer at interface
A:790 [TYR] R:3 [A] A:606 [ALA] B:3 [U] ❌ 5I4A_A:606 no longer at interface
A:790 [TYR] R:4 [A] A:606 [ALA] B:4 [A] ❌ 5I4A_A:606 no longer at interface
A:223 [ALA] R:8 [C] A:151 [PHE] B:8 [C] ❌ 5I4A_A:151 no longer at interface
A:221 [ALA] R:8 [C] A:149 [PHE] B:8 [C] ❌ 5I4A_A:149 no longer at interface
A:351 [ARG] R:8 [C] A:206 [PHE] B:8 [C] ❌ 5I4A_A:206 no longer at interface
A:351 [ARG] R:9 [U] A:206 [PHE] B:9 [C] ❌ 5I4A_A:206 no longer at interface
A:545 [GLN] R:1 [U] A:397 [GLN] B:1 [U] ❌ 5I4A_A:397 no longer at interface
A:545 [GLN] R:2 [A] A:397 [GLN] B:2 [A] ❌ 5I4A_A:397 no longer at interface
A:714 [ARG] R:8 [C] A:549 [ASN] B:8 [C] ❌ 5I4A_A:549 no longer at interface
A:364 [MET] R:8 [C] A:218 [PHE] B:8 [C] ❌ 5I4A_A:218 no longer at interface
A:353 [ILE] R:9 [U] A:208 [PHE] B:9 [C] ❌ 5I4A_A:208 no longer at interface
A:219 [VAL] R:8 [C] A:147 [PRO] B:8 [C] ❌ 5I4A_A:147 no longer at interface
A:570 [LYS] R:1 [U] A:422 [PHE] B:1 [U] ❌ 5I4A_A:422 no longer at interface
A:761 [ARG] R:8 [C] A:577 [LYS] B:8 [C] ❌ 5I4A_A:577 no longer at interface
A:222 [THR] R:8 [C] A:150 [THR] B:8 [C] ❌ 5I4A_A:150 no longer at interface
A:222 [THR] R:9 [U] A:150 [THR] B:9 [C] ❌ 5I4A_A:150 no longer at interface
A:544 [THR] R:1 [U] A:396 [LEU] B:1 [U] ❌ 5I4A_A:396 no longer at interface
A:712 [HIS] R:8 [C] A:547 [ASN] B:8 [C] ❌ 5I4A_A:547 no longer at interface
A:533 [LYS] R:1 [U] A:387 [VAL] B:1 [U] ❌ 5I4A_A:387 no longer at interface
A:177 [VAL] R:8 [C] A:104 [LYS] B:8 [C] ❌ 4F3T_A:177 no longer at interface
A:178 [GLY] R:9 [U] A:105 [LYS] B:9 [C] ❌ 4F3T_A:178 no longer at interface
A:178 [GLY] R:8 [C] A:105 [LYS] B:8 [C] ❌ 4F3T_A:178 no longer at interface
A:180 [SER] R:9 [U] A:108 [ASN] B:9 [C] ❌ 4F3T_A:180 no longer at interface
A:180 [SER] R:8 [C] A:108 [ASN] B:8 [C] ❌ 4F3T_A:180 no longer at interface
A:203 [HIS] R:9 [U] A:131 [LYS] B:9 [C] ❌ 4F3T_A:203 no longer at interface
A:203 [HIS] R:8 [C] A:131 [LYS] B:8 [C] ❌ 4F3T_A:203 no longer at interface
A:205 [SER] R:9 [U] A:133 [LYS] B:9 [C] ❌ 4F3T_A:205 no longer at interface
A:527 [PRO] R:1 [U] A:381 [GLY] B:1 [U] ❌ 4F3T_A:527 no longer at interface
A:808 [LEU] R:4 [A] A:625 [LYS] B:4 [A] ❌ 4F3T_A:808 no longer at interface
A:852 [THR] R:3 [A] A:635 [LEU] B:3 [U] ❌ 4F3T_A:852 no longer at interface
A:852 [THR] R:1 [U] A:635 [LEU] B:1 [U] ❌ 4F3T_A:852 no longer at interface
A:855 [THR] R:3 [A] A:636 [TYR] B:3 [U] ❌ 4F3T_A:855 no longer at interface
A:855 [THR] R:1 [U] A:636 [TYR] B:1 [U] ❌ 4F3T_A:855 no longer at interface

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Properties of this pair

Common ECOD label(s)
Common RFAM label(s)
Interface TM-score
Interface RMSD
Percentage identity
Protein TM-score
RNA TM-score
Protein coverage
RNA coverage
Percentage conservation
Apolar conservation
H-bond conservation
Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.77 3.27 0.03 0.77 0.15 0.42 0.43 0.56 0.62 0.15 0.80


Other pairs involving 4F3T_A_R or 5I4A_A_B

Total number of entries: 28

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4W5O_A_B,D 0.68 0.92 3.24 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6OZP_B_C,D 0.53 0.61 2.72 0.05 Ribonuclease H-like compare
4F3T_A_R 6OZS_B_C,D 0.56 0.61 2.75 0.09 Ribonuclease H-like compare
4F3T_A_R 6OZP_A_C,D 0.50 0.61 2.68 0.1 Ribonuclease H-like compare
4F3T_A_R 6OZS_A_C,D 0.49 0.61 2.63 0.1 Ribonuclease H-like compare
4F3T_A_R 4W5T_A_B,D 0.73 0.92 3.34 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6D92_A_C 0.53 0.71 3.42 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6CBD_A_B,C 0.79 0.91 3.2 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4OLA_A_B 0.99 0.99 0.3 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4KRE_A_R 0.99 0.98 1.27 0.27 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5JS1_A_B 0.98 0.99 0.4 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4KXT_A_B 0.98 0.97 1.12 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4F3T_A_R 4KRF_A_R 0.97 0.98 1.02 0.42 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5AWH_A_C 0.59 0.71 3.48 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6MFN_A_C,E 0.84 0.85 1.9 0.21 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4F3T_A_R 6OON_A_B 0.98 0.96 1.82 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4Z4D_A_B,D 0.70 0.92 3.19 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare