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All interfaces > All interologs > Interface groups > group140 > 4KRE_A_R

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Licorice
Surface

RNA

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Licorice
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Chain
Chain (with hetatm)
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Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

4KRE_A
4KRE_R
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:175 [VAL] R:9 [A] 4.4 74.24
A:217 [VAL] R:8 [A] 4.38 66.47
A:218 [SER] R:7 [A] 4.5 80.9
A:218 [SER] R:8 [A] 2.85 80.9
A:219 [ALA] R:7 [A] 3.34 59.38
A:219 [ALA] R:8 [A] 3.02 59.38
A:220 [THR] R:8 [A] 3.61 sugar:SC 77.07
A:220 [THR] R:9 [A] 4.65 77.07
A:269 [HIS] R:20 [A] 2.81 85.56
A:275 [ARG] R:19 [A] 3.33 sugar:SC 78.96
A:277 [TYR] R:19 [A] 3.1 sugar:SC 51.11
A:277 [TYR] R:20 [A] 4.68 51.11
A:292 [PHE] R:20 [A] 3.25 base/AA stacks 87.84
A:293 [PRO] R:20 [A] 3.44 7.01
A:294 [LEU] R:20 [A] 3.6 3.17
A:306 [VAL] R:20 [A] 4.14 95.86
A:309 [TYR] R:19 [A] 4.38 92.46
A:309 [TYR] R:20 [A] 2.72 92.46
A:310 [PHE] R:20 [A] 3.67 88.82
A:313 [LYS] R:19 [A] 4.43 54.26
A:313 [LYS] R:20 [A] 4.73 54.26
A:314 [TYR] R:19 [A] 4.25 88.62
A:314 [TYR] R:20 [A] 2.54 88.62
A:334 [HIS] R:19 [A] 4.53 22.12
A:334 [HIS] R:20 [A] 2.81 base:SC, sugar:BB 22.12
A:335 [THR] R:19 [A] 3.59 58.39
A:335 [THR] R:20 [A] 3.42 58.39
A:336 [TYR] R:20 [A] 2.78 sugar:BB 61.58
A:337 [LEU] R:20 [A] 3.84 59.33
A:349 [ARG] R:8 [A] 4.14 72.6
A:349 [ARG] R:9 [A] 3.31 72.6
A:354 [LEU] R:7 [A] 4.75 81.83
A:359 [THR] R:7 [A] 3.44 77.12
A:362 [MET] R:7 [A] 3.5 81.54
A:362 [MET] R:8 [A] 3.81 81.54
A:363 [ILE] R:6 [U] 3.47 86.92
A:363 [ILE] R:7 [A] 3.47 86.92
A:366 [THR] R:7 [A] 3.07 sugar:SC 79.86
A:367 [ALA] R:6 [U] 4.23 79.74
A:373 [ARG] R:7 [A] 4.0 96.38
A:520 [LEU] R:1 [A] 3.44 69.54
A:522 [GLY] R:1 [A] 3.84 30.52
A:523 [LYS] R:1 [A] 4.23 40.06
A:524 [THR] R:1 [A] 4.04 49.75
A:527 [TYR] R:1 [A] 2.59 base/AA stacks 93.27
A:531 [LYS] R:1 [A] 2.68 98.97
A:542 [THR] R:1 [A] 3.78 93.88
A:543 [GLN] R:1 [A] 2.82 96.89
A:543 [GLN] R:2 [A] 4.6 96.89
A:544 [CYS] R:1 [A] 2.98 87.29
A:544 [CYS] R:2 [A] 3.84 87.29
A:545 [VAL] R:1 [A] 3.9 79.61
A:545 [VAL] R:2 [A] 3.62 79.61
A:546 [GLN] R:1 [A] 2.95 sugar:SC 43.12
A:546 [GLN] R:2 [A] 2.84 43.12
A:549 [ASN] R:2 [A] 2.82 76.95
A:556 [GLN] R:2 [A] 4.24 67.46
A:557 [THR] R:2 [A] 3.36 72.64
A:560 [ASN] R:2 [A] 3.02 base:SC 97.61
A:560 [ASN] R:3 [U] 4.04 97.61
A:561 [LEU] R:2 [A] 3.53 79.06
A:564 [LYS] R:1 [A] 2.61 98.83
A:564 [LYS] R:2 [A] 3.34 98.83
A:564 [LYS] R:3 [U] 2.75 98.83
A:568 [LYS] R:1 [A] 3.22 98.72
A:707 [LYS] R:5 [U] 4.88 98.86
A:707 [LYS] R:6 [U] 2.78 98.86
A:708 [ARG] R:9 [A] 3.33 base/AA stacks 94.91
A:710 [HIS] R:8 [A] 3.37 88.04
A:712 [ARG] R:6 [U] 4.98 97.0
A:712 [ARG] R:7 [A] 2.79 97.0
A:712 [ARG] R:8 [A] 4.78 97.0
A:751 [HIS] R:5 [U] 3.18 94.58
A:751 [HIS] R:6 [U] 2.88 94.58
A:752 [ALA] R:5 [U] 4.29 67.68
A:753 [GLY] R:5 [U] 4.06 85.51
A:754 [ILE] R:4 [A] 3.4 81.06
A:754 [ILE] R:5 [U] 3.12 sugar:BB 81.06
A:755 [GLN] R:5 [U] 3.42 sugar:BB 81.64
A:755 [GLN] R:6 [U] 3.18 81.64
A:756 [GLY] R:6 [U] 4.48 98.83
A:757 [THR] R:6 [U] 3.39 98.81
A:757 [THR] R:7 [A] 3.71 98.81
A:758 [SER] R:5 [U] 4.93 91.46
A:758 [SER] R:6 [U] 3.35 91.46
A:759 [ARG] R:6 [U] 2.7 90.35
A:759 [ARG] R:7 [A] 2.78 90.35
A:759 [ARG] R:8 [A] 2.2 90.35
A:759 [ARG] R:9 [A] 4.95 90.35
A:788 [TYR] R:3 [U] 4.51 78.34
A:788 [TYR] R:4 [A] 2.54 78.34
A:790 [ARG] R:3 [U] 3.42 96.83
A:790 [ARG] R:4 [A] 3.01 96.83
A:791 [CYS] R:3 [U] 3.26 87.62
A:791 [CYS] R:4 [A] 3.7 87.62
A:793 [ARG] R:3 [U] 4.78 90.79
A:793 [ARG] R:4 [A] 3.05 sugar:SC 90.79
A:795 [VAL] R:4 [A] 3.74 94.55
A:795 [VAL] R:5 [U] 3.73 94.55
A:796 [SER] R:4 [A] 4.57 98.86
A:796 [SER] R:5 [U] 2.66 98.86
A:796 [SER] R:6 [U] 4.62 98.86
A:797 [ILE] R:5 [U] 4.72 73.08
A:802 [TYR] R:4 [A] 3.53 76.03
A:802 [TYR] R:5 [U] 2.64 76.03
A:810 [ARG] R:1 [A] 3.47 98.53
A:813 [TYR] R:1 [A] 2.67 base:SC 0.56
A:857 [ALA] R:1 [A] 4.05 75.18
A:857 [ALA] R:3 [U] 4.6 75.18

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group140 4KRE_A_R A: Protein argonaute-1, Homo sapiens (genetically engineered) R: Spodoptera frugiperda (natural) Q9UL18 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs ✘

Interologs

Total number of interologs for this interface: 18

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4KRE_A_R 4KRF_A_R 0.99 1.0 0.36 0.18 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OON_A_B 0.96 0.98 0.65 0.45 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4KRE_A_R 0.99 0.98 1.27 0.27 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4OLA_A_B 1.00 0.97 1.39 0.5 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5JS1_A_B 0.98 0.97 1.31 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4KXT_A_B 0.96 0.96 1.84 0.55 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 4Z4D_A_B,D 0.86 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5O_A_B,D 0.84 0.94 2.22 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5T_A_B,D 0.84 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6CBD_A_B,C 0.86 0.93 2.27 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6MFN_A_C,E 0.86 0.87 1.83 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5AWH_A_C 0.64 0.71 3.88 0.0 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6D92_A_C 0.62 0.7 3.92 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OZP_B_C,D 0.54 0.62 2.51 0.05 Ribonuclease H-like compare
4KRE_A_R 6OZS_A_C,D 0.62 0.62 2.57 0.1 Ribonuclease H-like compare
4KRE_A_R 6OZP_A_C,D 0.62 0.62 2.58 0.1 Ribonuclease H-like compare
4KRE_A_R 6OZS_B_C,D 0.56 0.62 2.54 0.09 Ribonuclease H-like compare