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All interfaces > All interologs > Interface groups > group140 > 4KRE_A_R vs 4OLA_A_B

Interface analysis


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Common contacts -

4KRE_A
4KRE_R
4OLA_A
4OLA_B
Conserved?
A:810 [ARG] R:1 [A] A:812 [ARG] B:1 [A]
A:710 [HIS] R:8 [A] A:712 [HIS] B:8 [A]
A:543 [GLN] R:1 [A] A:545 [GLN] B:1 [A]
A:543 [GLN] R:2 [A] A:545 [GLN] B:2 [A]
A:292 [PHE] R:20 [A] A:294 [PHE] B:21 [U]
A:527 [TYR] R:1 [A] A:529 [TYR] B:1 [A]
A:220 [THR] R:8 [A] A:222 [THR] B:8 [A]
A:366 [THR] R:7 [A] A:368 [THR] B:7 [A]
A:362 [MET] R:7 [A] A:364 [MET] B:7 [A]
A:362 [MET] R:8 [A] A:364 [MET] B:8 [A]
A:790 [ARG] R:3 [U] A:792 [ARG] B:3 [A]
A:790 [ARG] R:4 [A] A:792 [ARG] B:4 [A]
A:309 [TYR] R:20 [A] A:311 [TYR] B:21 [U]
A:337 [LEU] R:20 [A] A:339 [LEU] B:21 [U]
A:788 [TYR] R:3 [U] A:790 [TYR] B:3 [A]
A:788 [TYR] R:4 [A] A:790 [TYR] B:4 [A]
A:277 [TYR] R:20 [A] A:279 [TYR] B:21 [U]
A:219 [ALA] R:7 [A] A:221 [ALA] B:7 [A]
A:219 [ALA] R:8 [A] A:221 [ALA] B:8 [A]
A:542 [THR] R:1 [A] A:544 [THR] B:1 [A]
A:797 [ILE] R:5 [U] A:799 [ILE] B:5 [A]
A:791 [CYS] R:3 [U] A:793 [CYS] B:3 [A]
A:791 [CYS] R:4 [A] A:793 [CYS] B:4 [A]
A:363 [ILE] R:6 [U] A:365 [ILE] B:6 [A]
A:363 [ILE] R:7 [A] A:365 [ILE] B:7 [A]
A:367 [ALA] R:6 [U] A:369 [ALA] B:6 [A]
A:544 [CYS] R:1 [A] A:546 [CYS] B:1 [A]
A:544 [CYS] R:2 [A] A:546 [CYS] B:2 [A]
A:755 [GLN] R:5 [U] A:757 [GLN] B:5 [A]
A:755 [GLN] R:6 [U] A:757 [GLN] B:6 [A]
A:560 [ASN] R:2 [A] A:562 [ASN] B:2 [A]
A:560 [ASN] R:3 [U] A:562 [ASN] B:3 [A]
A:349 [ARG] R:8 [A] A:351 [ARG] B:8 [A]
A:813 [TYR] R:1 [A] A:815 [TYR] B:1 [A]
A:802 [TYR] R:4 [A] A:804 [TYR] B:4 [A]
A:802 [TYR] R:5 [U] A:804 [TYR] B:5 [A]
A:306 [VAL] R:20 [A] A:308 [VAL] B:21 [U]
A:568 [LYS] R:1 [A] A:570 [LYS] B:1 [A]
A:545 [VAL] R:1 [A] A:547 [VAL] B:1 [A]
A:545 [VAL] R:2 [A] A:547 [VAL] B:2 [A]
A:796 [SER] R:4 [A] A:798 [SER] B:4 [A]
A:796 [SER] R:5 [U] A:798 [SER] B:5 [A]
A:796 [SER] R:6 [U] A:798 [SER] B:6 [A]
A:217 [VAL] R:8 [A] A:219 [VAL] B:8 [A]
A:751 [HIS] R:5 [U] A:753 [HIS] B:5 [A]
A:751 [HIS] R:6 [U] A:753 [HIS] B:6 [A]
A:294 [LEU] R:20 [A] A:296 [LEU] B:21 [U]
A:793 [ARG] R:4 [A] A:795 [ARG] B:4 [A]
A:520 [LEU] R:1 [A] A:522 [LEU] B:1 [A]
A:522 [GLY] R:1 [A] A:524 [GLY] B:1 [A]
A:557 [THR] R:2 [A] A:559 [THR] B:2 [A]
A:373 [ARG] R:7 [A] A:375 [ARG] B:7 [A]
A:564 [LYS] R:1 [A] A:566 [LYS] B:1 [A]
A:564 [LYS] R:2 [A] A:566 [LYS] B:2 [A]
A:564 [LYS] R:3 [U] A:566 [LYS] B:3 [A]
A:795 [VAL] R:4 [A] A:797 [VAL] B:4 [A]
A:795 [VAL] R:5 [U] A:797 [VAL] B:5 [A]
A:707 [LYS] R:6 [U] A:709 [LYS] B:6 [A]
A:293 [PRO] R:20 [A] A:295 [PRO] B:21 [U]
A:758 [SER] R:5 [U] A:760 [SER] B:5 [A]
A:758 [SER] R:6 [U] A:760 [SER] B:6 [A]
A:531 [LYS] R:1 [A] A:533 [LYS] B:1 [A]
A:336 [TYR] R:20 [A] A:338 [TYR] B:21 [U]
A:524 [THR] R:1 [A] A:526 [THR] B:1 [A]
A:561 [LEU] R:2 [A] A:563 [LEU] B:2 [A]
A:556 [GLN] R:2 [A] A:558 [GLN] B:2 [A]
A:354 [LEU] R:7 [A] A:356 [LEU] B:7 [A]
A:754 [ILE] R:4 [A] A:756 [ILE] B:4 [A]
A:754 [ILE] R:5 [U] A:756 [ILE] B:5 [A]
A:757 [THR] R:6 [U] A:759 [THR] B:6 [A]
A:757 [THR] R:7 [A] A:759 [THR] B:7 [A]
A:313 [LYS] R:20 [A] A:315 [ARG] B:21 [U]
A:310 [PHE] R:20 [A] A:312 [PHE] B:21 [U]
A:756 [GLY] R:6 [U] A:758 [GLY] B:6 [A]
A:712 [ARG] R:6 [U] A:714 [ARG] B:6 [A]
A:712 [ARG] R:7 [A] A:714 [ARG] B:7 [A]
A:712 [ARG] R:8 [A] A:714 [ARG] B:8 [A]
A:546 [GLN] R:1 [A] A:548 [GLN] B:1 [A]
A:546 [GLN] R:2 [A] A:548 [GLN] B:2 [A]
A:359 [THR] R:7 [A] A:361 [THR] B:7 [A]
A:218 [SER] R:7 [A] A:220 [SER] B:7 [A]
A:218 [SER] R:8 [A] A:220 [SER] B:8 [A]
A:759 [ARG] R:6 [U] A:761 [ARG] B:6 [A]
A:759 [ARG] R:7 [A] A:761 [ARG] B:7 [A]
A:759 [ARG] R:8 [A] A:761 [ARG] B:8 [A]
A:314 [TYR] R:20 [A] A:316 [HIS] B:21 [U]
A:752 [ALA] R:5 [U] A:754 [ALA] B:5 [A]
A:523 [LYS] R:1 [A] A:525 [LYS] B:1 [A]
A:549 [ASN] R:2 [A] A:551 [ASN] B:2 [A]
A:334 [HIS] R:20 [A] A:336 [HIS] B:21 [U]
A:753 [GLY] R:5 [U] A:755 [GLY] B:5 [A]
A:857 [ALA] R:1 [A] A:859 [ALA] B:1 [A]
A:857 [ALA] R:3 [U] A:859 [ALA] B:3 [A]
A:335 [THR] R:20 [A] A:337 [THR] B:21 [U]
A:793 [ARG] R:3 [U] A:795 [ARG] B:3 [A] ❌ 4OLA_A_B
A:707 [LYS] R:5 [U] A:709 [LYS] B:5 [A] ❌ 4OLA_A_B
A:549 [ASN] R:1 [A] A:551 [ASN] B:1 [A] ❌ 4KRE_A_R
A:708 [ARG] R:8 [A] A:710 [ARG] B:8 [A] ❌ 4KRE_A_R

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Properties of this pair

Common ECOD label(s)
Common RFAM label(s)
Interface TM-score
Interface RMSD
Percentage identity
Protein TM-score
RNA TM-score
Protein coverage
RNA coverage
Percentage conservation
Apolar conservation
H-bond conservation
Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.97 1.39 0.50 0.97 0.58 1.0 0.9 1.00 0.96 0.74 0.00


Other pairs involving 4KRE_A_R or 4OLA_A_B

Total number of entries: 35

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
4F3T_A_R 4OLA_A_B 0.99 0.99 0.3 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4KRE_A_R 0.99 0.98 1.27 0.27 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OZP_B_C,D 0.54 0.62 2.51 0.05 Ribonuclease H-like compare
4KRE_A_R 5AWH_A_C 0.64 0.71 3.88 0.0 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4OLA_A_B 1.00 0.97 1.39 0.5 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4KRF_A_R 0.99 1.0 0.36 0.18 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OZS_A_C,D 0.62 0.62 2.57 0.1 Ribonuclease H-like compare
4KRE_A_R 6OZP_A_C,D 0.62 0.62 2.58 0.1 Ribonuclease H-like compare
4KRE_A_R 4Z4D_A_B,D 0.86 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6CBD_A_B,C 0.86 0.93 2.27 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4KXT_A_B 0.96 0.96 1.84 0.55 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5JS1_A_B 0.98 0.97 1.31 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6MFN_A_C,E 0.86 0.87 1.83 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4KRE_A_R 6D92_A_C 0.62 0.7 3.92 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5O_A_B,D 0.84 0.94 2.22 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OON_A_B 0.96 0.98 0.65 0.45 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5T_A_B,D 0.84 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OZS_B_C,D 0.56 0.62 2.54 0.09 Ribonuclease H-like compare
4KRF_A_R 4OLA_A_B 0.98 0.98 1.1 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 4OLA_A_B 0.98 0.98 0.92 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4OLA_A_B 6OZS_B_C,D 0.51 0.6 2.64 0.09 Ribonuclease H-like compare
4OLA_A_B 6OZP_B_C,D 0.50 0.6 2.63 0.05 Ribonuclease H-like compare
4OLA_A_B 6MFN_A_C,E 0.88 0.86 1.81 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4OLA_A_B 4W5O_A_B,D 0.92 0.92 3.08 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OZS_A_C,D 0.57 0.6 2.63 0.1 Ribonuclease H-like compare
4OLA_A_B 5AWH_A_C 0.63 0.71 3.34 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OZP_A_C,D 0.58 0.6 2.64 0.1 Ribonuclease H-like compare
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 4W5T_A_B,D 0.91 0.93 3.22 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 4Z4D_A_B,D 0.95 0.93 3.04 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6CBD_A_B,C 0.95 0.91 3.17 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OON_A_B 0.99 0.95 1.78 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6D92_A_C 0.61 0.7 3.32 0.1 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 5JS1_A_B 0.99 1.0 0.31 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare