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All interfaces > All interologs > Interface groups > group140 > 4KRE_A_R vs 5AWH_A_C

Interface analysis


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Common contacts -

4KRE_A
4KRE_R
5AWH_A
5AWH_C
Conserved?
A:543 [GLN] R:1 [A] A:478 [GLN] C:1 [U]
A:543 [GLN] R:2 [A] A:478 [GLN] C:2 [U]
A:527 [TYR] R:1 [A] A:463 [TYR] C:1 [U]
A:366 [THR] R:7 [A] A:271 [GLU] C:7 [C]
A:790 [ARG] R:3 [U] A:731 [ARG] C:3 [A]
A:790 [ARG] R:4 [A] A:731 [ARG] C:4 [C]
A:542 [THR] R:1 [A] A:477 [THR] C:1 [U]
A:791 [CYS] R:3 [U] A:732 [SER] C:3 [A]
A:791 [CYS] R:4 [A] A:732 [SER] C:4 [C]
A:544 [CYS] R:1 [A] A:479 [GLN] C:1 [U]
A:544 [CYS] R:2 [A] A:479 [GLN] C:2 [U]
A:755 [GLN] R:5 [U] A:696 [THR] C:5 [A]
A:755 [GLN] R:6 [U] A:696 [THR] C:6 [A]
A:560 [ASN] R:2 [A] A:498 [ASN] C:2 [U]
A:560 [ASN] R:3 [U] A:498 [ASN] C:3 [A]
A:813 [TYR] R:1 [A] A:754 [ARG] C:1 [U]
A:802 [TYR] R:4 [A] A:743 [PHE] C:4 [C]
A:568 [LYS] R:1 [A] A:506 [LYS] C:1 [U]
A:545 [VAL] R:1 [A] A:480 [VAL] C:1 [U]
A:545 [VAL] R:2 [A] A:480 [VAL] C:2 [U]
A:796 [SER] R:4 [A] A:737 [ALA] C:4 [C]
A:796 [SER] R:5 [U] A:737 [ALA] C:5 [A]
A:751 [HIS] R:5 [U] A:686 [ASN] C:5 [A]
A:751 [HIS] R:6 [U] A:686 [ASN] C:6 [A]
A:793 [ARG] R:4 [A] A:734 [LEU] C:4 [C]
A:520 [LEU] R:1 [A] A:449 [LEU] C:1 [U]
A:557 [THR] R:2 [A] A:495 [THR] C:2 [U]
A:795 [VAL] R:4 [A] A:736 [ALA] C:4 [C]
A:795 [VAL] R:5 [U] A:736 [ALA] C:5 [A]
A:758 [SER] R:6 [U] A:699 [PRO] C:6 [A]
A:531 [LYS] R:1 [A] A:467 [LYS] C:1 [U]
A:561 [LEU] R:2 [A] A:499 [PHE] C:2 [U]
A:556 [GLN] R:2 [A] A:494 [TYR] C:2 [U]
A:756 [GLY] R:6 [U] A:697 [PRO] C:6 [A]
A:546 [GLN] R:1 [A] A:481 [ARG] C:1 [U]
A:546 [GLN] R:2 [A] A:481 [ARG] C:2 [U]
A:523 [LYS] R:1 [A] A:454 [ALA] C:1 [U]
A:549 [ASN] R:2 [A] A:484 [THR] C:2 [U]
A:857 [ALA] R:1 [A] A:777 [LEU] C:1 [U]
A:857 [ALA] R:3 [U] A:777 [LEU] C:3 [A]
A:219 [ALA] R:7 [A] A:175 [GLY] C:7 [C] ❌ 5AWH_A_C
A:802 [TYR] R:5 [U] A:743 [PHE] C:5 [A] ❌ 5AWH_A_C
A:796 [SER] R:6 [U] A:737 [ALA] C:6 [A] ❌ 5AWH_A_C
A:793 [ARG] R:3 [U] A:734 [LEU] C:3 [A] ❌ 5AWH_A_C
A:758 [SER] R:5 [U] A:699 [PRO] C:5 [A] ❌ 5AWH_A_C
A:220 [THR] R:7 [A] A:176 [MET] C:7 [C] ❌ 4KRE_A_R
A:543 [GLN] R:3 [U] A:478 [GLN] C:3 [A] ❌ 4KRE_A_R
A:549 [ASN] R:1 [A] A:484 [THR] C:1 [U] ❌ 4KRE_A_R
A:756 [GLY] R:7 [A] A:697 [PRO] C:7 [C] ❌ 4KRE_A_R
A:790 [ARG] R:2 [A] A:731 [ARG] C:2 [U] ❌ 4KRE_A_R
A:810 [ARG] R:1 [A] A:751 [LEU] C:1 [U] ❌ 5AWH_A:751 no longer at interface
A:362 [MET] R:7 [A] A:265 [ASN] C:7 [C] ❌ 5AWH_A:265 no longer at interface
A:788 [TYR] R:3 [U] A:729 [SER] C:3 [A] ❌ 5AWH_A:729 no longer at interface
A:788 [TYR] R:4 [A] A:729 [SER] C:4 [C] ❌ 5AWH_A:729 no longer at interface
A:797 [ILE] R:5 [U] A:738 [THR] C:5 [A] ❌ 5AWH_A:738 no longer at interface
A:363 [ILE] R:6 [U] A:267 [LEU] C:6 [A] ❌ 5AWH_A:267 no longer at interface
A:363 [ILE] R:7 [A] A:267 [LEU] C:7 [C] ❌ 5AWH_A:267 no longer at interface
A:367 [ALA] R:6 [U] A:272 [ALA] C:6 [A] ❌ 5AWH_A:272 no longer at interface
A:522 [GLY] R:1 [A] A:451 [GLU] C:1 [U] ❌ 5AWH_A:451 no longer at interface
A:373 [ARG] R:7 [A] A:280 [PHE] C:7 [C] ❌ 5AWH_A:280 no longer at interface
A:564 [LYS] R:1 [A] A:502 [ALA] C:1 [U] ❌ 5AWH_A:502 no longer at interface
A:564 [LYS] R:2 [A] A:502 [ALA] C:2 [U] ❌ 5AWH_A:502 no longer at interface
A:564 [LYS] R:3 [U] A:502 [ALA] C:3 [A] ❌ 5AWH_A:502 no longer at interface
A:707 [LYS] R:5 [U] A:639 [HIS] C:5 [A] ❌ 5AWH_A:639 no longer at interface
A:707 [LYS] R:6 [U] A:639 [HIS] C:6 [A] ❌ 5AWH_A:639 no longer at interface
A:524 [THR] R:1 [A] A:455 [ARG] C:1 [U] ❌ 5AWH_A:455 no longer at interface
A:354 [LEU] R:7 [A] A:246 [GLU] C:7 [C] ❌ 5AWH_A:246 no longer at interface
A:754 [ILE] R:4 [A] A:691 [ILE] C:4 [C] ❌ 5AWH_A:691 no longer at interface
A:754 [ILE] R:5 [U] A:691 [ILE] C:5 [A] ❌ 5AWH_A:691 no longer at interface
A:757 [THR] R:6 [U] A:698 [LEU] C:6 [A] ❌ 5AWH_A:698 no longer at interface
A:757 [THR] R:7 [A] A:698 [LEU] C:7 [C] ❌ 5AWH_A:698 no longer at interface
A:712 [ARG] R:6 [U] A:644 [VAL] C:6 [A] ❌ 5AWH_A:644 no longer at interface
A:712 [ARG] R:7 [A] A:644 [VAL] C:7 [C] ❌ 5AWH_A:644 no longer at interface
A:218 [SER] R:7 [A] A:174 [ILE] C:7 [C] ❌ 5AWH_A:174 no longer at interface
A:759 [ARG] R:6 [U] A:700 [THR] C:6 [A] ❌ 5AWH_A:700 no longer at interface
A:759 [ARG] R:7 [A] A:700 [THR] C:7 [C] ❌ 5AWH_A:700 no longer at interface
A:752 [ALA] R:5 [U] A:687 [SER] C:5 [A] ❌ 5AWH_A:687 no longer at interface
A:753 [GLY] R:5 [U] A:690 [LEU] C:5 [A] ❌ 5AWH_A:690 no longer at interface
A:222 [PHE] R:7 [A] A:178 [TYR] C:7 [C] ❌ 4KRE_A:222 no longer at interface
A:353 [LYS] R:7 [A] A:245 [LYS] C:7 [C] ❌ 4KRE_A:353 no longer at interface
A:368 [ARG] R:7 [A] A:275 [ARG] C:7 [C] ❌ 4KRE_A:368 no longer at interface
A:525 [PRO] R:1 [A] A:461 [ASN] C:1 [U] ❌ 4KRE_A:525 no longer at interface
A:794 [SER] R:5 [U] A:735 [PRO] C:5 [A] ❌ 4KRE_A:794 no longer at interface
A:794 [SER] R:4 [A] A:735 [PRO] C:4 [C] ❌ 4KRE_A:794 no longer at interface

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Properties of this pair

Common ECOD label(s)
Common RFAM label(s)
Interface TM-score
Interface RMSD
Percentage identity
Protein TM-score
RNA TM-score
Protein coverage
RNA coverage
Percentage conservation
Apolar conservation
H-bond conservation
Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.71 3.88 0.00 0.71 0.24 0.51 0.64 0.64 0.62 0.30 0.77


Other pairs involving 4KRE_A_R or 5AWH_A_C

Total number of entries: 30

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
4OLA_A_B 5AWH_A_C 0.63 0.71 3.34 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 5AWH_A_C 0.50 0.71 3.34 0.13 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 6OZP_B_C,D 0.54 0.62 2.51 0.05 Ribonuclease H-like compare
4KRE_A_R 5AWH_A_C 0.64 0.71 3.88 0.0 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4OLA_A_B 1.00 0.97 1.39 0.5 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4KRF_A_R 0.99 1.0 0.36 0.18 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OZS_A_C,D 0.62 0.62 2.57 0.1 Ribonuclease H-like compare
4KRE_A_R 6OZP_A_C,D 0.62 0.62 2.58 0.1 Ribonuclease H-like compare
4KRE_A_R 4Z4D_A_B,D 0.86 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6CBD_A_B,C 0.86 0.93 2.27 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4KXT_A_B 0.96 0.96 1.84 0.55 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5JS1_A_B 0.98 0.97 1.31 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6MFN_A_C,E 0.86 0.87 1.83 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4KRE_A_R 6D92_A_C 0.62 0.7 3.92 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5O_A_B,D 0.84 0.94 2.22 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OON_A_B 0.96 0.98 0.65 0.45 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5T_A_B,D 0.84 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OZS_B_C,D 0.56 0.62 2.54 0.09 Ribonuclease H-like compare
5AWH_A_C 6D92_A_C 0.99 1.0 0.3 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6CBD_A_B,C 0.59 0.71 3.34 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 5JS1_A_B 0.62 0.71 4.1 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6OON_A_B 0.65 0.7 3.84 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6MFN_A_C,E 0.67 0.7 2.74 0.18 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5AWH_A_C 0.59 0.71 4.13 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5AWH_A_C 0.59 0.71 3.99 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5AWH_A_C 0.48 0.71 3.98 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5AWH_A_C 0.52 0.72 3.76 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4KRE_A_R 0.99 0.98 1.27 0.27 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5AWH_A_C 0.59 0.71 3.48 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare