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All interfaces > All interologs > Interface groups > group140 > 4KXT_A_B

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Licorice
Surface

RNA

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Licorice
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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

4KXT_A
4KXT_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:178 [SER] B:9 [A] 4.96 81.61
A:217 [VAL] B:8 [A] 4.5 67.75
A:218 [SER] B:7 [A] 4.7 84.08
A:218 [SER] B:8 [A] 2.69 84.08
A:219 [ALA] B:7 [A] 3.21 sugar:BB 61.74
A:219 [ALA] B:8 [A] 3.04 61.74
A:220 [THR] B:8 [A] 4.13 78.09
A:269 [HIS] B:21 [U] 2.98 84.42
A:275 [ARG] B:20 [U] 3.78 80.06
A:277 [TYR] B:20 [U] 3.09 sugar:SC 54.0
A:277 [TYR] B:21 [U] 4.77 54.0
A:292 [PHE] B:21 [U] 3.25 base/AA stacks 84.95
A:293 [PRO] B:21 [U] 3.99 base:BB 13.84
A:294 [LEU] B:21 [U] 3.57 12.87
A:295 [GLN] B:20 [U] 3.46 58.72
A:295 [GLN] B:21 [U] 3.56 base:BB 58.72
A:306 [VAL] B:21 [U] 4.29 95.52
A:309 [TYR] B:20 [U] 4.6 93.73
A:309 [TYR] B:21 [U] 2.8 93.73
A:310 [PHE] B:21 [U] 3.61 88.35
A:313 [LYS] B:19 [A] 3.03 51.32
A:313 [LYS] B:20 [U] 3.54 51.32
A:313 [LYS] B:21 [U] 3.71 51.32
A:314 [TYR] B:19 [A] 4.62 87.89
A:314 [TYR] B:20 [U] 4.26 87.89
A:314 [TYR] B:21 [U] 2.6 87.89
A:333 [LYS] B:20 [U] 4.47 70.57
A:333 [LYS] B:21 [U] 3.89 70.57
A:334 [HIS] B:21 [U] 2.8 sugar:BB 35.81
A:335 [THR] B:20 [U] 4.14 55.34
A:335 [THR] B:21 [U] 3.4 55.34
A:336 [TYR] B:21 [U] 2.82 sugar:BB 60.93
A:337 [LEU] B:21 [U] 3.71 57.76
A:349 [ARG] B:8 [A] 4.47 74.98
A:349 [ARG] B:9 [A] 3.3 74.98
A:354 [LEU] B:7 [A] 4.31 82.56
A:359 [THR] B:7 [A] 3.42 80.04
A:362 [MET] B:7 [A] 4.22 81.05
A:363 [ILE] B:6 [A] 3.48 88.0
A:363 [ILE] B:7 [A] 3.98 88.0
A:366 [THR] B:7 [A] 3.12 sugar:SC 84.2
A:367 [ALA] B:6 [A] 3.84 80.95
A:367 [ALA] B:7 [A] 4.68 80.95
A:373 [ARG] B:7 [A] 3.66 97.93
A:520 [LEU] B:1 [A] 3.71 78.75
A:522 [GLY] B:1 [A] 3.12 36.11
A:523 [LYS] B:1 [A] 3.3 43.14
A:524 [THR] B:1 [A] 2.92 base:BB 53.97
A:527 [TYR] B:1 [A] 2.67 base/AA stacks 92.74
A:531 [LYS] B:1 [A] 2.57 99.0
A:542 [THR] B:1 [A] 3.73 93.97
A:543 [GLN] B:1 [A] 2.88 98.44
A:543 [GLN] B:2 [A] 4.65 98.44
A:544 [CYS] B:1 [A] 2.95 89.87
A:544 [CYS] B:2 [A] 3.77 89.87
A:545 [VAL] B:1 [A] 3.94 80.66
A:545 [VAL] B:2 [A] 3.77 80.66
A:546 [GLN] B:1 [A] 2.98 base:SC 39.87
A:546 [GLN] B:2 [A] 2.85 39.87
A:549 [ASN] B:1 [A] 4.87 80.48
A:549 [ASN] B:2 [A] 2.56 80.48
A:556 [GLN] B:2 [A] 4.19 68.32
A:557 [THR] B:2 [A] 3.13 71.52
A:560 [ASN] B:2 [A] 3.01 base:SC 98.44
A:560 [ASN] B:3 [A] 3.89 98.44
A:561 [LEU] B:2 [A] 3.47 81.14
A:564 [LYS] B:1 [A] 2.76 99.0
A:564 [LYS] B:2 [A] 3.25 99.0
A:564 [LYS] B:3 [A] 2.96 99.0
A:568 [LYS] B:1 [A] 3.18 98.81
A:707 [LYS] B:5 [A] 4.9 98.97
A:707 [LYS] B:6 [A] 2.76 98.97
A:710 [HIS] B:8 [A] 4.18 87.97
A:710 [HIS] B:9 [A] 4.17 87.97
A:712 [ARG] B:6 [A] 4.73 97.37
A:712 [ARG] B:7 [A] 2.56 97.37
A:712 [ARG] B:8 [A] 4.52 97.37
A:751 [HIS] B:5 [A] 3.17 94.61
A:751 [HIS] B:6 [A] 2.88 94.61
A:752 [ALA] B:5 [A] 4.16 63.03
A:753 [GLY] B:5 [A] 4.18 86.93
A:754 [ILE] B:4 [A] 3.48 83.78
A:754 [ILE] B:5 [A] 3.19 sugar:BB 83.78
A:755 [GLN] B:5 [A] 3.18 sugar:BB 82.04
A:755 [GLN] B:6 [A] 3.07 82.04
A:756 [GLY] B:6 [A] 4.65 98.38
A:757 [THR] B:6 [A] 3.51 98.97
A:757 [THR] B:7 [A] 3.57 98.97
A:758 [SER] B:5 [A] 4.94 92.55
A:758 [SER] B:6 [A] 3.48 92.55
A:759 [ARG] B:6 [A] 2.85 90.17
A:759 [ARG] B:7 [A] 2.96 90.17
A:759 [ARG] B:8 [A] 2.73 90.17
A:788 [TYR] B:3 [A] 4.49 79.15
A:788 [TYR] B:4 [A] 2.65 79.15
A:790 [ARG] B:3 [A] 3.37 95.47
A:790 [ARG] B:4 [A] 2.94 95.47
A:791 [CYS] B:3 [A] 3.39 88.59
A:791 [CYS] B:4 [A] 3.64 88.59
A:793 [ARG] B:4 [A] 3.48 89.66
A:795 [VAL] B:4 [A] 3.82 94.42
A:795 [VAL] B:5 [A] 3.8 94.42
A:796 [SER] B:4 [A] 4.7 98.36
A:796 [SER] B:5 [A] 2.73 98.36
A:796 [SER] B:6 [A] 4.82 98.36
A:797 [ILE] B:5 [A] 4.84 75.55
A:802 [TYR] B:4 [A] 3.6 75.53
A:802 [TYR] B:5 [A] 2.63 75.53
A:810 [ARG] B:1 [A] 3.57 95.84
A:813 [TYR] B:1 [A] 3.58 base:SC 0.03
A:857 [ALA] B:1 [A] 4.01 70.38
A:857 [ALA] B:3 [A] 4.51 70.38

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group140 4KXT_A_B A: Protein argonaute-1, Homo sapiens (genetically engineered) B: RNA, Spodoptera frugiperda (natural) Q9UL18 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 ✘

Interologs

Total number of interologs for this interface: 18

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4KXT_A_B 6D92_A_C 0.48 0.71 3.26 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZS_A_C,D 0.57 0.59 2.56 0.09 Ribonuclease H-like compare
4KXT_A_B 6OZP_B_C,D 0.48 0.61 2.62 0.05 Ribonuclease H-like compare
4KXT_A_B 5JS1_A_B 0.97 0.98 0.84 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4W5T_A_B,D 0.89 0.91 3.15 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5AWH_A_C 0.50 0.71 3.34 0.13 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6CBD_A_B,C 0.91 0.9 2.96 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZS_B_C,D 0.51 0.61 2.64 0.09 Ribonuclease H-like compare
4KXT_A_B 4W5O_A_B,D 0.87 0.91 3.12 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4Z4D_A_B,D 0.87 0.91 2.97 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4OLA_A_B 0.98 0.98 0.92 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZP_A_C,D 0.57 0.6 2.58 0.08 Ribonuclease H-like compare
4KXT_A_B 6OON_A_B 0.95 0.95 2.24 0.83 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6MFN_A_C,E 0.90 0.85 1.72 0.17 Ribonuclease H-like & Argonaute, N-terminal domain compare
4KRE_A_R 4KXT_A_B 0.96 0.96 1.84 0.55 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRF_A_R 4KXT_A_B 0.95 0.97 1.54 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4F3T_A_R 4KXT_A_B 0.98 0.97 1.12 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare