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All interfaces > All interologs > Interface groups > group140 > 4KXT_A_B vs 6D92_A_C

Interface analysis


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Common contacts -

4KXT_A
4KXT_B
6D92_A
6D92_C
Conserved?
A:543 [GLN] B:1 [A] A:478 [GLN] C:1 [U]
A:543 [GLN] B:2 [A] A:478 [GLN] C:2 [U]
A:790 [ARG] B:3 [A] A:731 [ARG] C:3 [A]
A:790 [ARG] B:4 [A] A:731 [ARG] C:4 [C]
A:542 [THR] B:1 [A] A:477 [THR] C:1 [U]
A:791 [CYS] B:3 [A] A:732 [SER] C:3 [A]
A:791 [CYS] B:4 [A] A:732 [SER] C:4 [C]
A:544 [CYS] B:1 [A] A:479 [GLN] C:1 [U]
A:544 [CYS] B:2 [A] A:479 [GLN] C:2 [U]
A:755 [GLN] B:5 [A] A:696 [THR] C:5 [U]
A:755 [GLN] B:6 [A] A:696 [THR] C:6 [G]
A:560 [ASN] B:2 [A] A:498 [ASN] C:2 [U]
A:560 [ASN] B:3 [A] A:498 [ASN] C:3 [A]
A:813 [TYR] B:1 [A] A:754 [ARG] C:1 [U]
A:802 [TYR] B:4 [A] A:743 [PHE] C:4 [C]
A:568 [LYS] B:1 [A] A:506 [LYS] C:1 [U]
A:545 [VAL] B:1 [A] A:480 [VAL] C:1 [U]
A:545 [VAL] B:2 [A] A:480 [VAL] C:2 [U]
A:796 [SER] B:4 [A] A:737 [ALA] C:4 [C]
A:796 [SER] B:5 [A] A:737 [ALA] C:5 [U]
A:793 [ARG] B:4 [A] A:734 [LEU] C:4 [C]
A:751 [HIS] B:5 [A] A:686 [ASN] C:5 [U]
A:751 [HIS] B:6 [A] A:686 [ASN] C:6 [G]
A:520 [LEU] B:1 [A] A:449 [LEU] C:1 [U]
A:557 [THR] B:2 [A] A:495 [THR] C:2 [U]
A:795 [VAL] B:4 [A] A:736 [ALA] C:4 [C]
A:795 [VAL] B:5 [A] A:736 [ALA] C:5 [U]
A:524 [THR] B:1 [A] A:454 [ALA] C:1 [U]
A:758 [SER] B:6 [A] A:699 [PRO] C:6 [G]
A:561 [LEU] B:2 [A] A:499 [PHE] C:2 [U]
A:556 [GLN] B:2 [A] A:494 [TYR] C:2 [U]
A:756 [GLY] B:6 [A] A:697 [PRO] C:6 [G]
A:546 [GLN] B:1 [A] A:481 [ARG] C:1 [U]
A:546 [GLN] B:2 [A] A:481 [ARG] C:2 [U]
A:549 [ASN] B:1 [A] A:484 [THR] C:1 [U]
A:549 [ASN] B:2 [A] A:484 [THR] C:2 [U]
A:857 [ALA] B:1 [A] A:777 [LEU] C:1 [U]
A:857 [ALA] B:3 [A] A:777 [LEU] C:3 [A]
A:219 [ALA] B:7 [A] A:175 [GLY] C:7 [C] ❌ 6D92_A_C
A:802 [TYR] B:5 [A] A:743 [PHE] C:5 [U] ❌ 6D92_A_C
A:796 [SER] B:6 [A] A:737 [ALA] C:6 [G] ❌ 6D92_A_C
A:758 [SER] B:5 [A] A:699 [PRO] C:5 [U] ❌ 6D92_A_C
A:220 [THR] B:7 [A] A:176 [MET] C:7 [C] ❌ 4KXT_A_B
A:543 [GLN] B:3 [A] A:478 [GLN] C:3 [A] ❌ 4KXT_A_B
A:756 [GLY] B:7 [A] A:697 [PRO] C:7 [C] ❌ 4KXT_A_B
A:790 [ARG] B:2 [A] A:731 [ARG] C:2 [U] ❌ 4KXT_A_B
A:810 [ARG] B:1 [A] A:751 [LEU] C:1 [U] ❌ 6D92_A:751 no longer at interface
A:527 [TYR] B:1 [A] A:462 [PRO] C:1 [U] ❌ 6D92_A:462 no longer at interface
A:366 [THR] B:7 [A] A:271 [GLU] C:7 [C] ❌ 6D92_A:271 no longer at interface
A:362 [MET] B:7 [A] A:267 [LEU] C:7 [C] ❌ 6D92_A:267 no longer at interface
A:788 [TYR] B:3 [A] A:729 [SER] C:3 [A] ❌ 6D92_A:729 no longer at interface
A:788 [TYR] B:4 [A] A:729 [SER] C:4 [C] ❌ 6D92_A:729 no longer at interface
A:797 [ILE] B:5 [A] A:738 [THR] C:5 [U] ❌ 6D92_A:738 no longer at interface
A:363 [ILE] B:6 [A] A:268 [ASP] C:6 [G] ❌ 6D92_A:268 no longer at interface
A:363 [ILE] B:7 [A] A:268 [ASP] C:7 [C] ❌ 6D92_A:268 no longer at interface
A:367 [ALA] B:6 [A] A:272 [ALA] C:6 [G] ❌ 6D92_A:272 no longer at interface
A:367 [ALA] B:7 [A] A:272 [ALA] C:7 [C] ❌ 6D92_A:272 no longer at interface
A:522 [GLY] B:1 [A] A:451 [GLU] C:1 [U] ❌ 6D92_A:451 no longer at interface
A:373 [ARG] B:7 [A] A:280 [PHE] C:7 [C] ❌ 6D92_A:280 no longer at interface
A:564 [LYS] B:1 [A] A:502 [ALA] C:1 [U] ❌ 6D92_A:502 no longer at interface
A:564 [LYS] B:2 [A] A:502 [ALA] C:2 [U] ❌ 6D92_A:502 no longer at interface
A:564 [LYS] B:3 [A] A:502 [ALA] C:3 [A] ❌ 6D92_A:502 no longer at interface
A:707 [LYS] B:5 [A] A:639 [HIS] C:5 [U] ❌ 6D92_A:639 no longer at interface
A:707 [LYS] B:6 [A] A:639 [HIS] C:6 [G] ❌ 6D92_A:639 no longer at interface
A:531 [LYS] B:1 [A] A:466 [THR] C:1 [U] ❌ 6D92_A:466 no longer at interface
A:354 [LEU] B:7 [A] A:246 [GLU] C:7 [C] ❌ 6D92_A:246 no longer at interface
A:754 [ILE] B:4 [A] A:691 [ILE] C:4 [C] ❌ 6D92_A:691 no longer at interface
A:754 [ILE] B:5 [A] A:691 [ILE] C:5 [U] ❌ 6D92_A:691 no longer at interface
A:757 [THR] B:6 [A] A:698 [LEU] C:6 [G] ❌ 6D92_A:698 no longer at interface
A:757 [THR] B:7 [A] A:698 [LEU] C:7 [C] ❌ 6D92_A:698 no longer at interface
A:712 [ARG] B:6 [A] A:644 [VAL] C:6 [G] ❌ 6D92_A:644 no longer at interface
A:712 [ARG] B:7 [A] A:644 [VAL] C:7 [C] ❌ 6D92_A:644 no longer at interface
A:359 [THR] B:7 [A] A:252 [LEU] C:7 [C] ❌ 6D92_A:252 no longer at interface
A:218 [SER] B:7 [A] A:174 [ILE] C:7 [C] ❌ 6D92_A:174 no longer at interface
A:759 [ARG] B:6 [A] A:700 [THR] C:6 [G] ❌ 6D92_A:700 no longer at interface
A:759 [ARG] B:7 [A] A:700 [THR] C:7 [C] ❌ 6D92_A:700 no longer at interface
A:752 [ALA] B:5 [A] A:687 [SER] C:5 [U] ❌ 6D92_A:687 no longer at interface
A:523 [LYS] B:1 [A] A:452 [ASP] C:1 [U] ❌ 6D92_A:452 no longer at interface
A:753 [GLY] B:5 [A] A:688 [PRO] C:5 [U] ❌ 6D92_A:688 no longer at interface
A:222 [PHE] B:7 [A] A:178 [TYR] C:7 [C] ❌ 4KXT_A:222 no longer at interface
A:353 [LYS] B:6 [A] A:245 [LYS] C:6 [G] ❌ 4KXT_A:353 no longer at interface
A:353 [LYS] B:7 [A] A:245 [LYS] C:7 [C] ❌ 4KXT_A:353 no longer at interface
A:368 [ARG] B:7 [A] A:275 [ARG] C:7 [C] ❌ 4KXT_A:368 no longer at interface
A:525 [PRO] B:1 [A] A:455 [ARG] C:1 [U] ❌ 4KXT_A:525 no longer at interface
A:526 [VAL] B:1 [A] A:461 [ASN] C:1 [U] ❌ 4KXT_A:526 no longer at interface
A:528 [ALA] B:1 [A] A:463 [TYR] C:1 [U] ❌ 4KXT_A:528 no longer at interface
A:532 [ARG] B:1 [A] A:467 [LYS] C:1 [U] ❌ 4KXT_A:532 no longer at interface
A:794 [SER] B:5 [A] A:735 [PRO] C:5 [U] ❌ 4KXT_A:794 no longer at interface
A:794 [SER] B:4 [A] A:735 [PRO] C:4 [C] ❌ 4KXT_A:794 no longer at interface

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Properties of this pair

Common ECOD label(s)
Common RFAM label(s)
Interface TM-score
Interface RMSD
Percentage identity
Protein TM-score
RNA TM-score
Protein coverage
RNA coverage
Percentage conservation
Apolar conservation
H-bond conservation
Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 0.71 3.26 0.08 0.72 0.27 0.42 0.58 0.48 0.37 0.25 0.84


Other pairs involving 4KXT_A_B or 6D92_A_C

Total number of entries: 30

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
4OLA_A_B 6D92_A_C 0.61 0.7 3.32 0.1 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 6D92_A_C 0.48 0.71 3.26 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZS_A_C,D 0.57 0.59 2.56 0.09 Ribonuclease H-like compare
4KXT_A_B 6OZP_B_C,D 0.48 0.61 2.62 0.05 Ribonuclease H-like compare
4KXT_A_B 5JS1_A_B 0.97 0.98 0.84 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4W5T_A_B,D 0.89 0.91 3.15 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5AWH_A_C 0.50 0.71 3.34 0.13 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6CBD_A_B,C 0.91 0.9 2.96 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZS_B_C,D 0.51 0.61 2.64 0.09 Ribonuclease H-like compare
4KXT_A_B 4W5O_A_B,D 0.87 0.91 3.12 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4Z4D_A_B,D 0.87 0.91 2.97 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4OLA_A_B 0.98 0.98 0.92 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZP_A_C,D 0.57 0.6 2.58 0.08 Ribonuclease H-like compare
4KXT_A_B 6OON_A_B 0.95 0.95 2.24 0.83 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6MFN_A_C,E 0.90 0.85 1.72 0.17 Ribonuclease H-like & Argonaute, N-terminal domain compare
4KRE_A_R 4KXT_A_B 0.96 0.96 1.84 0.55 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 6D92_A_C 0.62 0.7 3.92 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6D92_A_C 6OON_A_B 0.64 0.7 3.88 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6D92_A_C 6MFN_A_C,E 0.65 0.7 2.72 0.12 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
5JS1_A_B 6D92_A_C 0.60 0.71 3.43 0.15 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6D92_A_C 0.99 1.0 0.3 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6D92_A_C 0.59 0.71 4.22 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6D92_A_C 0.59 0.71 4.07 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 6D92_A_C 0.62 0.71 4.01 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 4KXT_A_B 0.95 0.97 1.54 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4W5T_A_B,D 6D92_A_C 0.53 0.71 3.89 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6D92_A_C 0.53 0.71 3.42 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4KXT_A_B 0.98 0.97 1.12 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
6CBD_A_B,C 6D92_A_C 0.57 0.71 3.31 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare