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All interfaces > All interologs > Interface groups > group140 > 4OLA_A_B vs 5I4A_A_B

Interface analysis


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Common contacts -

4OLA_A
4OLA_B
5I4A_A
5I4A_B
Conserved?
A:756 [ILE] B:4 [A] A:573 [PHE] B:4 [A] ✔
A:547 [VAL] B:1 [A] A:399 [ILE] B:1 [U] ✔
A:547 [VAL] B:2 [A] A:399 [ILE] B:2 [A] ✔
A:815 [TYR] B:1 [A] A:632 [GLU] B:1 [U] ✔
A:804 [TYR] B:4 [A] A:621 [HIS] B:4 [A] ✔
A:529 [TYR] B:1 [A] A:383 [ILE] B:1 [U] ✔
A:526 [THR] B:1 [A] A:380 [ILE] B:1 [U] ✔
A:566 [LYS] B:1 [A] A:418 [LYS] B:1 [U] ✔
A:566 [LYS] B:2 [A] A:418 [LYS] B:2 [A] ✔
A:566 [LYS] B:3 [A] A:418 [LYS] B:3 [U] ✔
A:797 [VAL] B:4 [A] A:614 [TYR] B:4 [A] ✔
A:548 [GLN] B:1 [A] A:400 [LEU] B:1 [U] ✔
A:548 [GLN] B:2 [A] A:400 [LEU] B:2 [A] ✔
A:525 [LYS] B:1 [A] A:379 [TYR] B:1 [U] ✔
A:522 [LEU] B:1 [A] A:376 [LEU] B:1 [U] ✔
A:792 [ARG] B:3 [A] A:608 [SER] B:3 [U] ✔
A:792 [ARG] B:4 [A] A:608 [SER] B:4 [A] ✔
A:563 [LEU] B:2 [A] A:415 [TYR] B:2 [A] ✔
A:798 [SER] B:4 [A] A:615 [LYS] B:4 [A] ✔
A:558 [GLN] B:2 [A] A:410 [PHE] B:2 [A] ✔
A:795 [ARG] B:4 [A] A:612 [THR] B:4 [A] ✔
A:551 [ASN] B:2 [A] A:403 [LYS] B:2 [A] ✔
A:546 [CYS] B:1 [A] A:398 [PRO] B:1 [U] ✔
A:546 [CYS] B:2 [A] A:398 [PRO] B:2 [A] ✔
A:562 [ASN] B:2 [A] A:414 [SER] B:2 [A] ✔
A:524 [GLY] B:1 [A] A:378 [LYS] B:1 [U] ✔
A:559 [THR] B:2 [A] A:411 [ILE] B:2 [A] ✔
A:793 [CYS] B:3 [A] A:609 [THR] B:3 [U] ✔
A:220 [SER] B:8 [A] A:148 [LYS] B:8 [C] ❌ 5I4A_A_B
A:551 [ASN] B:1 [A] A:403 [LYS] B:1 [U] ❌ 5I4A_A_B
A:710 [ARG] B:8 [A] A:545 [ASN] B:8 [C] ❌ 5I4A_A_B
A:710 [ARG] B:9 [A] A:545 [ASN] B:21 [U] ❌ 5I4A_A_B
A:562 [ASN] B:3 [A] A:414 [SER] B:3 [U] ❌ 5I4A_A_B
A:793 [CYS] B:4 [A] A:609 [THR] B:4 [A] ❌ 5I4A_A_B
A:339 [LEU] B:9 [A] A:198 [VAL] B:21 [U] ❌ 4OLA_A_B
A:525 [LYS] B:4 [A] A:379 [TYR] B:4 [A] ❌ 4OLA_A_B
A:551 [ASN] B:3 [A] A:403 [LYS] B:3 [U] ❌ 4OLA_A_B
A:757 [GLN] B:4 [A] A:574 [LEU] B:4 [A] ❌ 4OLA_A_B
A:793 [CYS] B:2 [A] A:609 [THR] B:2 [A] ❌ 4OLA_A_B
A:795 [ARG] B:3 [A] A:612 [THR] B:3 [U] ❌ 4OLA_A_B
A:364 [MET] B:8 [A] A:219 [SER] B:8 [C] ❌ 5I4A_A:219 no longer at interface
A:219 [VAL] B:8 [A] A:147 [PRO] B:8 [C] ❌ 5I4A_A:147 no longer at interface
A:544 [THR] B:1 [A] A:396 [LEU] B:1 [U] ❌ 5I4A_A:396 no longer at interface
A:812 [ARG] B:1 [A] A:629 [THR] B:1 [U] ❌ 5I4A_A:629 no longer at interface
A:790 [TYR] B:3 [A] A:606 [ALA] B:3 [U] ❌ 5I4A_A:606 no longer at interface
A:790 [TYR] B:4 [A] A:606 [ALA] B:4 [A] ❌ 5I4A_A:606 no longer at interface
A:570 [LYS] B:1 [A] A:422 [PHE] B:1 [U] ❌ 5I4A_A:422 no longer at interface
A:761 [ARG] B:8 [A] A:577 [LYS] B:8 [C] ❌ 5I4A_A:577 no longer at interface
A:221 [ALA] B:8 [A] A:149 [PHE] B:8 [C] ❌ 5I4A_A:149 no longer at interface
A:712 [HIS] B:8 [A] A:547 [ASN] B:8 [C] ❌ 5I4A_A:547 no longer at interface
A:533 [LYS] B:1 [A] A:387 [VAL] B:1 [U] ❌ 5I4A_A:387 no longer at interface
A:351 [ARG] B:8 [A] A:206 [PHE] B:8 [C] ❌ 5I4A_A:206 no longer at interface
A:351 [ARG] B:9 [A] A:206 [PHE] B:21 [U] ❌ 5I4A_A:206 no longer at interface
A:714 [ARG] B:8 [A] A:549 [ASN] B:8 [C] ❌ 5I4A_A:549 no longer at interface
A:545 [GLN] B:1 [A] A:397 [GLN] B:1 [U] ❌ 5I4A_A:397 no longer at interface
A:545 [GLN] B:2 [A] A:397 [GLN] B:2 [A] ❌ 5I4A_A:397 no longer at interface
A:222 [THR] B:8 [A] A:150 [THR] B:8 [C] ❌ 5I4A_A:150 no longer at interface
A:222 [THR] B:9 [A] A:150 [THR] B:21 [U] ❌ 5I4A_A:150 no longer at interface
A:177 [VAL] B:8 [A] A:104 [LYS] B:8 [C] ❌ 4OLA_A:177 no longer at interface
A:178 [GLY] B:8 [A] A:105 [LYS] B:8 [C] ❌ 4OLA_A:178 no longer at interface
A:180 [SER] B:8 [A] A:108 [ASN] B:8 [C] ❌ 4OLA_A:180 no longer at interface
A:203 [HIS] B:8 [A] A:131 [LYS] B:8 [C] ❌ 4OLA_A:203 no longer at interface
A:280 [ARG] B:9 [A] A:188 [ILE] B:21 [U] ❌ 4OLA_A:280 no longer at interface
A:282 [CYS] B:9 [A] A:190 [ILE] B:21 [U] ❌ 4OLA_A:282 no longer at interface
A:329 [GLN] B:9 [A] A:196 [VAL] B:21 [U] ❌ 4OLA_A:329 no longer at interface
A:344 [CYS] B:9 [A] A:199 [ALA] B:21 [U] ❌ 4OLA_A:344 no longer at interface
A:345 [ASN] B:9 [A] A:200 [TYR] B:21 [U] ❌ 4OLA_A:345 no longer at interface
A:349 [GLY] B:9 [A] A:204 [TYR] B:21 [U] ❌ 4OLA_A:349 no longer at interface
A:69 [ARG] B:9 [A] A:31 [ARG] B:21 [U] ❌ 4OLA_A:69 no longer at interface
A:527 [PRO] B:1 [A] A:381 [GLY] B:1 [U] ❌ 4OLA_A:527 no longer at interface
A:808 [LEU] B:4 [A] A:625 [LYS] B:4 [A] ❌ 4OLA_A:808 no longer at interface
A:852 [THR] B:3 [A] A:635 [LEU] B:3 [U] ❌ 4OLA_A:852 no longer at interface
A:852 [THR] B:1 [A] A:635 [LEU] B:1 [U] ❌ 4OLA_A:852 no longer at interface
A:855 [THR] B:3 [A] A:636 [TYR] B:3 [U] ❌ 4OLA_A:855 no longer at interface
A:855 [THR] B:1 [A] A:636 [TYR] B:1 [U] ❌ 4OLA_A:855 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.77 3.22 0.03 0.77 0.26 0.42 0.6 0.61 0.71 0.17 0.74


Other pairs involving 4OLA_A_B or 5I4A_A_B

Total number of entries: 28

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4OLA_A_B 0.99 0.99 0.3 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4OLA_A_B 1.00 0.97 1.39 0.5 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 4OLA_A_B 0.98 0.98 1.1 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4OLA_A_B 0.98 0.98 0.92 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4OLA_A_B 6OZS_B_C,D 0.51 0.6 2.64 0.09 Ribonuclease H-like compare
4OLA_A_B 6OZP_B_C,D 0.50 0.6 2.63 0.05 Ribonuclease H-like compare
4OLA_A_B 6MFN_A_C,E 0.88 0.86 1.81 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4OLA_A_B 4W5O_A_B,D 0.92 0.92 3.08 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OZS_A_C,D 0.57 0.6 2.63 0.1 Ribonuclease H-like compare
4OLA_A_B 5AWH_A_C 0.63 0.71 3.34 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OZP_A_C,D 0.58 0.6 2.64 0.1 Ribonuclease H-like compare
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 4W5T_A_B,D 0.91 0.93 3.22 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 4Z4D_A_B,D 0.95 0.93 3.04 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6CBD_A_B,C 0.95 0.91 3.17 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OON_A_B 0.99 0.95 1.78 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6D92_A_C 0.61 0.7 3.32 0.1 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 5JS1_A_B 0.99 1.0 0.31 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare