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All interfaces > All interologs > Interface groups > group140 > 4W5O_A_B,D vs 5AWH_A_C

Interface analysis


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Common contacts -

4W5O_A
4W5O_B,D
5AWH_A
5AWH_C
Conserved?
A:757 [GLN] B:5 [C] A:696 [THR] C:5 [A] ✔
A:757 [GLN] B:6 [A] A:696 [THR] C:6 [A] ✔
A:797 [VAL] B:4 [A] A:736 [ALA] C:4 [C] ✔
A:797 [VAL] B:5 [C] A:736 [ALA] C:5 [A] ✔
A:221 [ALA] B:8 [U] A:176 [MET] C:8 [C] ✔
A:562 [ASN] B:2 [U] A:498 [ASN] C:2 [U] ✔
A:562 [ASN] B:3 [C] A:498 [ASN] C:3 [A] ✔
A:545 [GLN] B:1 [U] A:478 [GLN] C:1 [U] ✔
A:545 [GLN] B:2 [U] A:478 [GLN] C:2 [U] ✔
A:793 [CYS] B:3 [C] A:732 [SER] C:3 [A] ✔
A:793 [CYS] B:4 [A] A:732 [SER] C:4 [C] ✔
A:526 [THR] B:1 [U] A:454 [ALA] C:1 [U] ✔
A:753 [HIS] B:5 [C] A:686 [ASN] C:5 [A] ✔
A:753 [HIS] B:6 [A] A:686 [ASN] C:6 [A] ✔
A:522 [LEU] B:1 [U] A:449 [LEU] C:1 [U] ✔
A:563 [LEU] B:2 [U] A:499 [PHE] C:2 [U] ✔
A:798 [SER] B:4 [A] A:737 [ALA] C:4 [C] ✔
A:798 [SER] B:5 [C] A:737 [ALA] C:5 [A] ✔
A:558 [GLN] B:2 [U] A:494 [TYR] C:2 [U] ✔
A:559 [THR] B:2 [U] A:495 [THR] C:2 [U] ✔
A:804 [TYR] B:4 [A] A:743 [PHE] C:4 [C] ✔
A:815 [TYR] B:1 [U] A:754 [ARG] C:1 [U] ✔
A:547 [VAL] B:1 [U] A:480 [VAL] C:1 [U] ✔
A:547 [VAL] B:2 [U] A:480 [VAL] C:2 [U] ✔
A:859 [ALA] B:1 [U] A:777 [LEU] C:1 [U] ✔
A:859 [ALA] B:3 [C] A:777 [LEU] C:3 [A] ✔
A:529 [TYR] B:1 [U] A:463 [TYR] C:1 [U] ✔
A:570 [LYS] B:1 [U] A:506 [LYS] C:1 [U] ✔
A:368 [THR] B:7 [U] A:271 [GLU] C:7 [C] ✔
A:760 [SER] B:6 [A] A:699 [PRO] C:6 [A] ✔
A:792 [ARG] B:3 [C] A:731 [ARG] C:3 [A] ✔
A:792 [ARG] B:4 [A] A:731 [ARG] C:4 [C] ✔
A:671 [VAL] B:11 [C] A:606 [ARG] C:13 [A] ✔
A:758 [GLY] B:6 [A] A:697 [PRO] C:6 [A] ✔
A:795 [ARG] B:4 [A] A:734 [LEU] C:4 [C] ✔
A:551 [ASN] B:2 [U] A:484 [THR] C:2 [U] ✔
A:546 [CYS] B:1 [U] A:479 [GLN] C:1 [U] ✔
A:546 [CYS] B:2 [U] A:479 [GLN] C:2 [U] ✔
A:544 [THR] B:1 [U] A:477 [THR] C:1 [U] ✔
A:548 [GLN] B:1 [U] A:481 [ARG] C:1 [U] ✔
A:548 [GLN] B:2 [U] A:481 [ARG] C:2 [U] ✔
A:533 [LYS] B:1 [U] A:467 [LYS] C:1 [U] ✔
A:798 [SER] B:6 [A] A:737 [ALA] C:6 [A] ❌ 5AWH_A_C
A:804 [TYR] B:5 [C] A:743 [PHE] C:5 [A] ❌ 5AWH_A_C
A:760 [SER] B:5 [C] A:699 [PRO] C:5 [A] ❌ 5AWH_A_C
A:221 [ALA] B:7 [U] A:176 [MET] C:7 [C] ❌ 4W5O_A_B,D
A:545 [GLN] B:3 [C] A:478 [GLN] C:3 [A] ❌ 4W5O_A_B,D
A:551 [ASN] B:1 [U] A:484 [THR] C:1 [U] ❌ 4W5O_A_B,D
A:758 [GLY] B:7 [U] A:697 [PRO] C:7 [C] ❌ 4W5O_A_B,D
A:792 [ARG] B:2 [U] A:731 [ARG] C:2 [U] ❌ 4W5O_A_B,D
A:709 [LYS] B:5 [C] A:639 [HIS] C:5 [A] ❌ 5AWH_A:639 no longer at interface
A:709 [LYS] B:6 [A] A:639 [HIS] C:6 [A] ❌ 5AWH_A:639 no longer at interface
A:812 [ARG] B:1 [U] A:751 [LEU] C:1 [U] ❌ 5AWH_A:751 no longer at interface
A:790 [TYR] B:3 [C] A:729 [SER] C:3 [A] ❌ 5AWH_A:729 no longer at interface
A:790 [TYR] B:4 [A] A:729 [SER] C:4 [C] ❌ 5AWH_A:729 no longer at interface
A:566 [LYS] B:1 [U] A:502 [ALA] C:1 [U] ❌ 5AWH_A:502 no longer at interface
A:566 [LYS] B:2 [U] A:502 [ALA] C:2 [U] ❌ 5AWH_A:502 no longer at interface
A:566 [LYS] B:3 [C] A:502 [ALA] C:3 [A] ❌ 5AWH_A:502 no longer at interface
A:755 [GLY] B:5 [C] A:690 [LEU] C:5 [A] ❌ 5AWH_A:690 no longer at interface
A:754 [ALA] B:5 [C] A:687 [SER] C:5 [A] ❌ 5AWH_A:687 no longer at interface
A:670 [GLY] B:11 [C] A:605 [HIS] C:13 [A] ❌ 5AWH_A:605 no longer at interface
A:710 [ARG] B:8 [U] A:640 [ASP] C:8 [C] ❌ 5AWH_A:640 no longer at interface
A:601 [PRO] B:11 [C] A:533 [LEU] C:13 [A] ❌ 5AWH_A:533 no longer at interface
A:375 [ARG] B:7 [U] A:280 [PHE] C:7 [C] ❌ 5AWH_A:280 no longer at interface
A:600 [HIS] B:11 [C] A:532 [GLU] C:13 [A] ❌ 5AWH_A:532 no longer at interface
A:714 [ARG] B:7 [U] A:644 [VAL] C:7 [C] ❌ 5AWH_A:644 no longer at interface
A:756 [ILE] B:4 [A] A:691 [ILE] C:4 [C] ❌ 5AWH_A:691 no longer at interface
A:756 [ILE] B:5 [C] A:691 [ILE] C:5 [A] ❌ 5AWH_A:691 no longer at interface
A:799 [ILE] B:5 [C] A:738 [THR] C:5 [A] ❌ 5AWH_A:738 no longer at interface
A:761 [ARG] B:6 [A] A:700 [THR] C:6 [A] ❌ 5AWH_A:700 no longer at interface
A:761 [ARG] B:7 [U] A:700 [THR] C:7 [C] ❌ 5AWH_A:700 no longer at interface
A:761 [ARG] B:8 [U] A:700 [THR] C:8 [C] ❌ 5AWH_A:700 no longer at interface
A:365 [ILE] B:6 [A] A:268 [ASP] C:6 [A] ❌ 5AWH_A:268 no longer at interface
A:365 [ILE] B:7 [U] A:268 [ASP] C:7 [C] ❌ 5AWH_A:268 no longer at interface
A:759 [THR] B:6 [A] A:698 [LEU] C:6 [A] ❌ 5AWH_A:698 no longer at interface
A:759 [THR] B:7 [U] A:698 [LEU] C:7 [C] ❌ 5AWH_A:698 no longer at interface
A:525 [LYS] B:1 [U] A:452 [ASP] C:1 [U] ❌ 5AWH_A:452 no longer at interface
A:524 [GLY] B:1 [U] A:451 [GLU] C:1 [U] ❌ 5AWH_A:451 no longer at interface
A:201 [GLY] B:8 [U] A:151 [ARG] C:8 [C] ❌ 4W5O_A:201 no longer at interface
A:220 [SER] B:8 [U] A:175 [GLY] C:8 [C] ❌ 4W5O_A:220 no longer at interface
A:222 [THR] B:8 [U] A:177 [ARG] C:8 [C] ❌ 4W5O_A:222 no longer at interface
A:223 [ALA] B:8 [U] A:178 [TYR] C:8 [C] ❌ 4W5O_A:223 no longer at interface
A:223 [ALA] B:7 [U] A:178 [TYR] C:7 [C] ❌ 4W5O_A:223 no longer at interface
A:353 [ILE] B:8 [U] A:243 [GLY] C:8 [C] ❌ 4W5O_A:353 no longer at interface
A:354 [LYS] B:8 [U] A:244 [SER] C:8 [C] ❌ 4W5O_A:354 no longer at interface
A:355 [LYS] B:8 [U] A:245 [LYS] C:8 [C] ❌ 4W5O_A:355 no longer at interface
A:355 [LYS] B:7 [U] A:245 [LYS] C:7 [C] ❌ 4W5O_A:355 no longer at interface
A:370 [ARG] B:8 [U] A:275 [ARG] C:8 [C] ❌ 4W5O_A:370 no longer at interface
A:370 [ARG] B:7 [U] A:275 [ARG] C:7 [C] ❌ 4W5O_A:370 no longer at interface
A:527 [PRO] B:1 [U] A:461 [ASN] C:1 [U] ❌ 4W5O_A:527 no longer at interface
A:554 [ARG] B:2 [U] A:487 [LEU] C:2 [U] ❌ 4W5O_A:554 no longer at interface
A:610 [SER] B:11 [C] A:543 [ARG] C:13 [A] ❌ 4W5O_A:610 no longer at interface
A:796 [SER] B:5 [C] A:735 [PRO] C:5 [A] ❌ 4W5O_A:796 no longer at interface
A:796 [SER] B:4 [A] A:735 [PRO] C:4 [C] ❌ 4W5O_A:796 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.71 3.99 0.16 0.72 0.22 0.51 0.5 0.59 0.59 0.29 0.85


Other pairs involving 4W5O_A_B,D or 5AWH_A_C

Total number of entries: 30

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 4W5O_A_B,D 0.92 0.92 3.08 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 5AWH_A_C 0.63 0.71 3.34 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 5AWH_A_C 0.50 0.71 3.34 0.13 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4W5O_A_B,D 0.87 0.91 3.12 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5AWH_A_C 0.64 0.71 3.88 0.0 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5O_A_B,D 0.84 0.94 2.22 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6D92_A_C 0.99 1.0 0.3 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6CBD_A_B,C 0.59 0.71 3.34 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 5JS1_A_B 0.62 0.71 4.1 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6OON_A_B 0.65 0.7 3.84 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6MFN_A_C,E 0.67 0.7 2.74 0.18 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5AWH_A_C 0.59 0.71 4.13 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5JS1_A_B 0.88 0.92 3.24 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6OZS_A_C,D 0.44 0.61 2.76 0.15 Ribonuclease H-like compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6MFN_A_C,E 0.85 0.92 1.55 0.76 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5AWH_A_C 0.59 0.71 3.99 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6OZP_A_C,D 0.57 0.61 2.77 0.15 Ribonuclease H-like compare
4W5O_A_B,D 6OON_A_B 0.90 0.96 1.89 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 4Z4D_A_B,D 0.96 1.0 0.12 0.96 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6D92_A_C 0.59 0.71 4.07 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 4W5T_A_B,D 0.94 0.99 0.26 0.92 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6CBD_A_B,C 0.99 1.0 0.36 0.97 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6OZP_B_C,D 0.48 0.63 2.71 0.1 Ribonuclease H-like compare
4W5O_A_B,D 6OZS_B_C,D 0.49 0.63 2.78 0.14 Ribonuclease H-like compare
4KRF_A_R 4W5O_A_B,D 0.86 0.92 2.36 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5AWH_A_C 0.48 0.71 3.98 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5AWH_A_C 0.52 0.72 3.76 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4W5O_A_B,D 0.68 0.92 3.24 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5AWH_A_C 0.59 0.71 3.48 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare