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All interfaces > All interologs > Interface groups > group140 > 4W5T_A_B,D vs 5I4A_A_B

Interface analysis


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Common contacts -

4W5T_A
4W5T_B,D
5I4A_A
5I4A_B
Conserved?
A:566 [LYS] B:1 [U] A:418 [LYS] B:1 [U] ✔
A:566 [LYS] B:2 [U] A:418 [LYS] B:2 [A] ✔
A:566 [LYS] B:3 [C] A:418 [LYS] B:3 [U] ✔
A:797 [VAL] B:4 [A] A:614 [TYR] B:4 [A] ✔
A:672 [SER] B:12 [C] A:518 [ARG] B:11 [A] ✔
A:562 [ASN] B:2 [U] A:414 [SER] B:2 [A] ✔
A:793 [CYS] B:3 [C] A:609 [THR] B:3 [U] ✔
A:526 [THR] B:1 [U] A:380 [ILE] B:1 [U] ✔
A:522 [LEU] B:1 [U] A:376 [LEU] B:1 [U] ✔
A:563 [LEU] B:2 [U] A:415 [TYR] B:2 [A] ✔
A:798 [SER] B:4 [A] A:615 [LYS] B:4 [A] ✔
A:558 [GLN] B:2 [U] A:410 [PHE] B:2 [A] ✔
A:559 [THR] B:2 [U] A:411 [ILE] B:2 [A] ✔
A:804 [TYR] B:4 [A] A:621 [HIS] B:4 [A] ✔
A:815 [TYR] B:1 [U] A:632 [GLU] B:1 [U] ✔
A:756 [ILE] B:4 [A] A:573 [PHE] B:4 [A] ✔
A:547 [VAL] B:1 [U] A:399 [ILE] B:1 [U] ✔
A:547 [VAL] B:2 [U] A:399 [ILE] B:2 [A] ✔
A:529 [TYR] B:1 [U] A:383 [ILE] B:1 [U] ✔
A:792 [ARG] B:3 [C] A:608 [SER] B:3 [U] ✔
A:792 [ARG] B:4 [A] A:608 [SER] B:4 [A] ✔
A:795 [ARG] B:4 [A] A:612 [THR] B:4 [A] ✔
A:551 [ASN] B:2 [U] A:403 [LYS] B:2 [A] ✔
A:546 [CYS] B:1 [U] A:398 [PRO] B:1 [U] ✔
A:546 [CYS] B:2 [U] A:398 [PRO] B:2 [A] ✔
A:548 [GLN] B:1 [U] A:400 [LEU] B:1 [U] ✔
A:548 [GLN] B:2 [U] A:400 [LEU] B:2 [A] ✔
A:525 [LYS] B:1 [U] A:379 [TYR] B:1 [U] ✔
A:524 [GLY] B:1 [U] A:378 [LYS] B:1 [U] ✔
A:710 [ARG] B:8 [U] A:545 [ASN] B:7 [A] ❌ 5I4A_A_B
A:710 [ARG] B:9 [G] A:545 [ASN] B:8 [C] ❌ 5I4A_A_B
A:562 [ASN] B:3 [C] A:414 [SER] B:3 [U] ❌ 5I4A_A_B
A:793 [CYS] B:4 [A] A:609 [THR] B:4 [A] ❌ 5I4A_A_B
A:220 [SER] B:8 [U] A:148 [LYS] B:7 [A] ❌ 5I4A_A_B
A:178 [GLY] B:14 [A] A:105 [LYS] B:12 [C] ❌ 5I4A_A_B
A:176 [PRO] B:14 [A] A:103 [PHE] B:12 [C] ❌ 5I4A_A_B
A:551 [ASN] B:1 [U] A:403 [LYS] B:1 [U] ❌ 5I4A_A_B
A:177 [VAL] B:14 [A] A:104 [LYS] B:12 [C] ❌ 5I4A_A_B
A:176 [PRO] B:12 [C] A:103 [PHE] B:11 [A] ❌ 4W5T_A_B,D
A:177 [VAL] B:9 [G] A:104 [LYS] B:8 [C] ❌ 4W5T_A_B,D
A:177 [VAL] B:8 [U] A:104 [LYS] B:7 [A] ❌ 4W5T_A_B,D
A:178 [GLY] B:9 [G] A:105 [LYS] B:8 [C] ❌ 4W5T_A_B,D
A:179 [ARG] B:12 [C] A:107 [ASN] B:11 [A] ❌ 4W5T_A_B,D
A:356 [LEU] B:8 [U] A:211 [ARG] B:7 [A] ❌ 4W5T_A_B,D
A:525 [LYS] B:4 [A] A:379 [TYR] B:4 [A] ❌ 4W5T_A_B,D
A:551 [ASN] B:3 [C] A:403 [LYS] B:3 [U] ❌ 4W5T_A_B,D
A:672 [SER] B:14 [A] A:518 [ARG] B:12 [C] ❌ 4W5T_A_B,D
A:757 [GLN] B:4 [A] A:574 [LEU] B:4 [A] ❌ 4W5T_A_B,D
A:793 [CYS] B:2 [U] A:609 [THR] B:2 [A] ❌ 4W5T_A_B,D
A:795 [ARG] B:3 [C] A:612 [THR] B:3 [U] ❌ 4W5T_A_B,D
A:635 [ARG] B:12 [C] A:480 [LEU] B:11 [A] ❌ 5I4A_A:480 no longer at interface
A:812 [ARG] B:1 [U] A:629 [THR] B:1 [U] ❌ 5I4A_A:629 no longer at interface
A:790 [TYR] B:3 [C] A:606 [ALA] B:3 [U] ❌ 5I4A_A:606 no longer at interface
A:790 [TYR] B:4 [A] A:606 [ALA] B:4 [A] ❌ 5I4A_A:606 no longer at interface
A:221 [ALA] B:8 [U] A:149 [PHE] B:7 [A] ❌ 5I4A_A:149 no longer at interface
A:351 [ARG] B:9 [G] A:206 [PHE] B:8 [C] ❌ 5I4A_A:206 no longer at interface
A:545 [GLN] B:1 [U] A:397 [GLN] B:1 [U] ❌ 5I4A_A:397 no longer at interface
A:545 [GLN] B:2 [U] A:397 [GLN] B:2 [A] ❌ 5I4A_A:397 no longer at interface
A:600 [HIS] B:9 [G] A:449 [HIS] B:8 [C] ❌ 5I4A_A:449 no longer at interface
A:68 [ARG] B:14 [A] A:30 [ALA] B:12 [C] ❌ 5I4A_A:30 no longer at interface
A:859 [ALA] B:1 [U] A:639 [TYR] B:1 [U] ❌ 5I4A_A:639 no longer at interface
A:859 [ALA] B:3 [C] A:639 [TYR] B:3 [U] ❌ 5I4A_A:639 no longer at interface
A:570 [LYS] B:1 [U] A:422 [PHE] B:1 [U] ❌ 5I4A_A:422 no longer at interface
A:761 [ARG] B:8 [U] A:577 [LYS] B:7 [A] ❌ 5I4A_A:577 no longer at interface
A:544 [THR] B:1 [U] A:396 [LEU] B:1 [U] ❌ 5I4A_A:396 no longer at interface
A:533 [LYS] B:1 [U] A:387 [VAL] B:1 [U] ❌ 5I4A_A:387 no longer at interface
A:180 [SER] B:9 [G] A:108 [ASN] B:8 [C] ❌ 4W5T_A:180 no longer at interface
A:203 [HIS] B:9 [G] A:131 [LYS] B:8 [C] ❌ 4W5T_A:203 no longer at interface
A:205 [SER] B:12 [C] A:133 [LYS] B:11 [A] ❌ 4W5T_A:205 no longer at interface
A:206 [VAL] B:12 [C] A:134 [ILE] B:11 [A] ❌ 4W5T_A:206 no longer at interface
A:352 [CYS] B:8 [U] A:207 [ASN] B:7 [A] ❌ 4W5T_A:352 no longer at interface
A:354 [LYS] B:8 [U] A:209 [THR] B:7 [A] ❌ 4W5T_A:354 no longer at interface
A:355 [LYS] B:8 [U] A:210 [THR] B:7 [A] ❌ 4W5T_A:355 no longer at interface
A:527 [PRO] B:1 [U] A:381 [GLY] B:1 [U] ❌ 4W5T_A:527 no longer at interface
A:808 [LEU] B:4 [A] A:625 [LYS] B:4 [A] ❌ 4W5T_A:808 no longer at interface
A:855 [THR] B:3 [C] A:635 [LEU] B:3 [U] ❌ 4W5T_A:855 no longer at interface
A:855 [THR] B:1 [U] A:635 [LEU] B:1 [U] ❌ 4W5T_A:855 no longer at interface
A:856 [MET] B:3 [C] A:636 [TYR] B:3 [U] ❌ 4W5T_A:856 no longer at interface
A:856 [MET] B:1 [U] A:636 [TYR] B:1 [U] ❌ 4W5T_A:856 no longer at interface
A:156 [PHE] B:14 [A] A:82 [LYS] B:12 [C] ❌ 4W5T_A:156 no longer at interface
A:159 [ILE] B:12 [C] A:85 [VAL] B:11 [A] ❌ 4W5T_A:159 no longer at interface
A:160 [GLN] B:12 [C] A:86 [LYS] B:11 [A] ❌ 4W5T_A:160 no longer at interface
A:163 [ASP] B:12 [C] A:89 [TYR] B:11 [A] ❌ 4W5T_A:163 no longer at interface
A:164 [VAL] B:12 [C] A:90 [LYS] B:11 [A] ❌ 4W5T_A:164 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.78 2.78 0.03 0.79 0.11 0.48 0.57 0.51 0.51 0.13 0.62


Other pairs involving 4W5T_A_B,D or 5I4A_A_B

Total number of entries: 28

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 4W5T_A_B,D 0.91 0.93 3.22 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 4W5T_A_B,D 0.89 0.91 3.15 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5T_A_B,D 0.84 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 4W5T_A_B,D 0.94 0.99 0.26 0.92 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 4W5T_A_B,D 0.82 0.93 2.41 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OZS_B_C,D 0.40 0.63 2.8 0.09 Ribonuclease H-like compare
4W5T_A_B,D 5AWH_A_C 0.52 0.72 3.76 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OON_A_B 0.88 0.96 1.87 0.42 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6D92_A_C 0.53 0.71 3.89 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OZP_A_C,D 0.54 0.61 2.85 0.1 Ribonuclease H-like compare
4W5T_A_B,D 6OZS_A_C,D 0.54 0.61 2.93 0.1 Ribonuclease H-like compare
4W5T_A_B,D 6OZP_B_C,D 0.37 0.63 2.75 0.05 Ribonuclease H-like compare
4W5T_A_B,D 4Z4D_A_B,D 0.91 0.99 0.27 0.88 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5JS1_A_B 0.87 0.92 3.34 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6MFN_A_C,E 0.83 0.93 1.53 0.59 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6CBD_A_B,C 0.94 0.99 0.4 0.88 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4W5T_A_B,D 0.73 0.92 3.34 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare