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All interfaces > All interologs > Interface groups > group140 > 4W5T_A_B,D vs 6OON_A_B

Interface analysis


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Common contacts -

4W5T_A
4W5T_B,D
6OON_A
6OON_B
Conserved?
A:757 [GLN] B:5 [C] A:759 [GLN] B:5 [A] ✔
A:757 [GLN] B:6 [A] A:759 [GLN] B:6 [A] ✔
A:709 [LYS] B:6 [A] A:711 [LYS] B:6 [A] ✔
A:279 [TYR] B:20 [U] A:269 [TYR] B:20 [U] ✔
A:279 [TYR] B:21 [U] A:269 [TYR] B:21 [U] ✔
A:812 [ARG] B:1 [U] A:814 [ARG] B:1 [A] ✔
A:790 [TYR] B:3 [C] A:792 [TYR] B:3 [A] ✔
A:790 [TYR] B:4 [A] A:792 [TYR] B:4 [A] ✔
A:566 [LYS] B:1 [U] A:558 [LYS] B:1 [A] ✔
A:566 [LYS] B:2 [U] A:558 [LYS] B:2 [A] ✔
A:566 [LYS] B:3 [C] A:558 [LYS] B:3 [A] ✔
A:797 [VAL] B:4 [A] A:799 [VAL] B:4 [A] ✔
A:797 [VAL] B:5 [C] A:799 [VAL] B:5 [A] ✔
A:755 [GLY] B:5 [C] A:757 [GLY] B:5 [A] ✔
A:754 [ALA] B:5 [C] A:756 [ALA] B:5 [A] ✔
A:221 [ALA] B:8 [U] A:211 [ALA] B:8 [A] ✔
A:339 [LEU] B:21 [U] A:329 [LEU] B:21 [U] ✔
A:710 [ARG] B:8 [U] A:712 [ARG] B:8 [A] ✔
A:562 [ASN] B:2 [U] A:554 [ASN] B:2 [A] ✔
A:562 [ASN] B:3 [C] A:554 [ASN] B:3 [A] ✔
A:545 [GLN] B:1 [U] A:537 [GLN] B:1 [A] ✔
A:545 [GLN] B:2 [U] A:537 [GLN] B:2 [A] ✔
A:311 [TYR] B:20 [U] A:301 [TYR] B:20 [U] ✔
A:311 [TYR] B:21 [U] A:301 [TYR] B:21 [U] ✔
A:793 [CYS] B:3 [C] A:795 [CYS] B:3 [A] ✔
A:793 [CYS] B:4 [A] A:795 [CYS] B:4 [A] ✔
A:294 [PHE] B:21 [U] A:284 [PHE] B:21 [U] ✔
A:526 [THR] B:1 [U] A:518 [THR] B:1 [A] ✔
A:375 [ARG] B:7 [U] A:365 [ARG] B:7 [A] ✔
A:753 [HIS] B:5 [C] A:755 [HIS] B:5 [A] ✔
A:753 [HIS] B:6 [A] A:755 [HIS] B:6 [A] ✔
A:522 [LEU] B:1 [U] A:514 [LEU] B:1 [A] ✔
A:220 [SER] B:8 [U] A:210 [SER] B:8 [A] ✔
A:563 [LEU] B:2 [U] A:555 [LEU] B:2 [A] ✔
A:798 [SER] B:4 [A] A:800 [SER] B:4 [A] ✔
A:798 [SER] B:5 [C] A:800 [SER] B:5 [A] ✔
A:798 [SER] B:6 [A] A:800 [SER] B:6 [A] ✔
A:336 [HIS] B:21 [U] A:327 [THR] B:21 [U] ✔
A:558 [GLN] B:2 [U] A:550 [GLN] B:2 [A] ✔
A:295 [PRO] B:21 [U] A:285 [PRO] B:21 [U] ✔
A:714 [ARG] B:6 [A] A:716 [ARG] B:6 [A] ✔
A:714 [ARG] B:7 [U] A:716 [ARG] B:7 [A] ✔
A:559 [THR] B:2 [U] A:551 [THR] B:2 [A] ✔
A:804 [TYR] B:4 [A] A:806 [TYR] B:4 [A] ✔
A:804 [TYR] B:5 [C] A:806 [TYR] B:5 [A] ✔
A:815 [TYR] B:1 [U] A:817 [TYR] B:1 [A] ✔
A:756 [ILE] B:4 [A] A:758 [ILE] B:4 [A] ✔
A:756 [ILE] B:5 [C] A:758 [ILE] B:5 [A] ✔
A:547 [VAL] B:1 [U] A:539 [VAL] B:1 [A] ✔
A:547 [VAL] B:2 [U] A:539 [VAL] B:2 [A] ✔
A:859 [ALA] B:1 [U] A:861 [ALA] B:1 [A] ✔
A:859 [ALA] B:3 [C] A:861 [ALA] B:3 [A] ✔
A:799 [ILE] B:5 [C] A:801 [ILE] B:5 [A] ✔
A:529 [TYR] B:1 [U] A:521 [TYR] B:1 [A] ✔
A:570 [LYS] B:1 [U] A:562 [LYS] B:1 [A] ✔
A:368 [THR] B:7 [U] A:358 [THR] B:7 [A] ✔
A:308 [VAL] B:21 [U] A:298 [VAL] B:21 [U] ✔
A:760 [SER] B:6 [A] A:762 [SER] B:6 [A] ✔
A:792 [ARG] B:3 [C] A:794 [ARG] B:3 [A] ✔
A:792 [ARG] B:4 [A] A:794 [ARG] B:4 [A] ✔
A:761 [ARG] B:6 [A] A:763 [ARG] B:6 [A] ✔
A:761 [ARG] B:7 [U] A:763 [ARG] B:7 [A] ✔
A:761 [ARG] B:8 [U] A:763 [ARG] B:8 [A] ✔
A:365 [ILE] B:7 [U] A:355 [ILE] B:7 [A] ✔
A:758 [GLY] B:6 [A] A:760 [GLY] B:6 [A] ✔
A:759 [THR] B:6 [A] A:761 [THR] B:6 [A] ✔
A:759 [THR] B:7 [U] A:761 [THR] B:7 [A] ✔
A:795 [ARG] B:4 [A] A:797 [ARG] B:4 [A] ✔
A:296 [LEU] B:21 [U] A:286 [LEU] B:21 [U] ✔
A:551 [ASN] B:2 [U] A:543 [ASN] B:2 [A] ✔
A:546 [CYS] B:1 [U] A:538 [CYS] B:1 [A] ✔
A:546 [CYS] B:2 [U] A:538 [CYS] B:2 [A] ✔
A:316 [HIS] B:21 [U] A:306 [TYR] B:21 [U] ✔
A:312 [PHE] B:21 [U] A:302 [PHE] B:21 [U] ✔
A:544 [THR] B:1 [U] A:536 [THR] B:1 [A] ✔
A:177 [VAL] B:14 [A] A:167 [VAL] B:9 [A] ✔
A:548 [GLN] B:1 [U] A:540 [GLN] B:1 [A] ✔
A:548 [GLN] B:2 [U] A:540 [GLN] B:2 [A] ✔
A:525 [LYS] B:1 [U] A:517 [LYS] B:1 [A] ✔
A:338 [TYR] B:21 [U] A:328 [TYR] B:21 [U] ✔
A:533 [LYS] B:1 [U] A:525 [LYS] B:1 [A] ✔
A:524 [GLY] B:1 [U] A:516 [GLY] B:1 [A] ✔
A:709 [LYS] B:5 [C] A:711 [LYS] B:5 [A] ❌ 6OON_A_B
A:710 [ARG] B:7 [U] A:712 [ARG] B:7 [A] ❌ 6OON_A_B
A:551 [ASN] B:1 [U] A:543 [ASN] B:1 [A] ❌ 6OON_A_B
A:220 [SER] B:7 [U] A:210 [SER] B:7 [A] ❌ 4W5T_A_B,D
A:221 [ALA] B:7 [U] A:211 [ALA] B:7 [A] ❌ 4W5T_A_B,D
A:356 [LEU] B:7 [U] A:346 [LEU] B:7 [A] ❌ 4W5T_A_B,D
A:361 [THR] B:7 [U] A:351 [THR] B:7 [A] ❌ 4W5T_A_B,D
A:365 [ILE] B:6 [A] A:355 [ILE] B:6 [A] ❌ 4W5T_A_B,D
A:710 [ARG] B:14 [A] A:712 [ARG] B:9 [A] ❌ 4W5T_A_B,D
A:714 [ARG] B:8 [U] A:716 [ARG] B:8 [A] ❌ 4W5T_A_B,D
A:760 [SER] B:5 [C] A:762 [SER] B:5 [A] ❌ 4W5T_A_B,D
A:795 [ARG] B:3 [C] A:797 [ARG] B:3 [A] ❌ 4W5T_A_B,D
A:178 [GLY] B:14 [A] A:168 [GLY] B:9 [A] ❌ 6OON_A:168 no longer at interface
A:68 [ARG] B:14 [A] A:58 [ARG] B:9 [A] ❌ 6OON_A:58 no longer at interface
A:277 [ARG] B:20 [U] A:267 [ARG] B:20 [U] ❌ 6OON_A:267 no longer at interface
A:277 [ARG] B:21 [U] A:267 [ARG] B:21 [U] ❌ 6OON_A:267 no longer at interface
A:176 [PRO] B:14 [A] A:166 [PRO] B:9 [A] ❌ 6OON_A:166 no longer at interface
A:219 [VAL] B:8 [U] A:209 [VAL] B:8 [A] ❌ 4W5T_A:219 no longer at interface
A:222 [THR] B:8 [U] A:212 [THR] B:8 [A] ❌ 4W5T_A:222 no longer at interface
A:315 [ARG] B:20 [U] A:305 [LYS] B:20 [U] ❌ 4W5T_A:315 no longer at interface
A:315 [ARG] B:21 [U] A:305 [LYS] B:21 [U] ❌ 4W5T_A:315 no longer at interface
A:364 [MET] B:7 [U] A:354 [MET] B:7 [A] ❌ 4W5T_A:364 no longer at interface
A:364 [MET] B:8 [U] A:354 [MET] B:8 [A] ❌ 4W5T_A:364 no longer at interface
A:369 [ALA] B:6 [A] A:359 [ALA] B:6 [A] ❌ 4W5T_A:369 no longer at interface
A:712 [HIS] B:8 [U] A:714 [HIS] B:8 [A] ❌ 4W5T_A:712 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.96 1.87 0.42 0.96 0.36 0.8 0.92 0.88 0.83 0.67 0.52


Other pairs involving 4W5T_A_B,D or 6OON_A_B

Total number of entries: 35

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 4W5T_A_B,D 0.91 0.93 3.22 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OON_A_B 0.99 0.95 1.78 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6MFN_A_C,E 6OON_A_B 0.88 0.89 1.67 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4KXT_A_B 4W5T_A_B,D 0.89 0.91 3.15 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OON_A_B 0.95 0.95 2.24 0.83 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 6OON_A_B 0.96 0.98 0.65 0.45 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 4W5T_A_B,D 0.84 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6D92_A_C 6OON_A_B 0.64 0.7 3.88 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OON_A_B 0.98 0.96 1.74 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6OON_A_B 6OZP_B_C,D 0.49 0.61 2.62 0.05 Ribonuclease H-like compare
6OON_A_B 6OZS_B_C,D 0.46 0.61 2.69 0.09 Ribonuclease H-like compare
6OON_A_B 6OZS_A_C,D 0.52 0.61 2.6 0.09 Ribonuclease H-like compare
6OON_A_B 6OZP_A_C,D 0.57 0.61 2.57 0.08 Ribonuclease H-like compare
5AWH_A_C 6OON_A_B 0.65 0.7 3.84 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OON_A_B 0.90 0.96 1.83 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6OON_A_B 0.90 0.96 1.89 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 4W5T_A_B,D 0.94 0.99 0.26 0.92 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 6OON_A_B 0.97 0.98 0.92 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 4W5T_A_B,D 0.82 0.93 2.41 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OZS_B_C,D 0.40 0.63 2.8 0.09 Ribonuclease H-like compare
4W5T_A_B,D 5AWH_A_C 0.52 0.72 3.76 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OON_A_B 0.88 0.96 1.87 0.42 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6D92_A_C 0.53 0.71 3.89 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OZP_A_C,D 0.54 0.61 2.85 0.1 Ribonuclease H-like compare
4W5T_A_B,D 6OZS_A_C,D 0.54 0.61 2.93 0.1 Ribonuclease H-like compare
4W5T_A_B,D 6OZP_B_C,D 0.37 0.63 2.75 0.05 Ribonuclease H-like compare
4W5T_A_B,D 4Z4D_A_B,D 0.91 0.99 0.27 0.88 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5JS1_A_B 0.87 0.92 3.34 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6MFN_A_C,E 0.83 0.93 1.53 0.59 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6CBD_A_B,C 0.94 0.99 0.4 0.88 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4W5T_A_B,D 0.73 0.92 3.34 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6OON_A_B 0.98 0.96 1.82 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6OON_A_B 0.90 0.95 1.87 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare