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All interfaces > All interologs > Interface groups > group140 > 4Z4D_A_B,D vs 6OZP_B_C,D

Interface analysis


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Common contacts -

4Z4D_A
4Z4D_B,D
6OZP_B
6OZP_C,D
Conserved?
A:797 [VAL] B:4 [A] B:230 [PHE] C:17 [A]
A:797 [VAL] B:5 [C] B:230 [PHE] C:18 [U]
A:755 [GLY] B:5 [C] B:202 [HIS] C:18 [U]
A:710 [ARG] B:8 [U] B:156 [LYS] C:22 [U]
A:710 [ARG] B:9 [G] B:156 [LYS] C:23 [U]
A:710 [ARG] B:10 [C] B:156 [LYS] D:35 [U]
A:598 [VAL] B:10 [C] B:53 [VAL] D:35 [U]
A:798 [SER] B:4 [A] B:231 [ARG] C:17 [A]
A:798 [SER] B:5 [C] B:231 [ARG] C:18 [U]
A:798 [SER] B:6 [A] B:231 [ARG] C:19 [G]
A:600 [HIS] B:10 [C] B:55 [PHE] D:35 [U]
A:804 [TYR] B:4 [A] B:237 [ARG] C:17 [A]
A:815 [TYR] B:1 [U] B:248 [ARG] C:14 [U]
A:756 [ILE] B:5 [C] B:203 [SER] C:18 [U]
A:760 [SER] B:5 [C] B:204 [THR] C:18 [U]
A:760 [SER] B:6 [A] B:204 [THR] C:19 [G]
A:761 [ARG] B:6 [A] B:205 [LYS] C:19 [G]
A:761 [ARG] B:7 [U] B:205 [LYS] C:20 [C]
A:599 [THR] B:10 [C] B:54 [SER] D:35 [U]
A:709 [LYS] B:5 [C] B:155 [LYS] C:18 [U] ❌ 6OZP_B_C,D
A:709 [LYS] B:6 [A] B:155 [LYS] C:19 [G] ❌ 6OZP_B_C,D
A:804 [TYR] B:5 [C] B:237 [ARG] C:18 [U] ❌ 6OZP_B_C,D
A:815 [TYR] D:23 [A] B:248 [ARG] D:37 [U] ❌ 6OZP_B_C,D
A:756 [ILE] B:4 [A] B:203 [SER] C:17 [A] ❌ 6OZP_B_C,D
A:761 [ARG] B:8 [U] B:205 [LYS] C:22 [U] ❌ 6OZP_B_C,D
A:602 [PRO] B:9 [G] B:57 [LYS] C:23 [U] ❌ 6OZP_B_C,D
A:602 [PRO] B:10 [C] B:57 [LYS] D:35 [U] ❌ 6OZP_B_C,D
A:811 [PHE] B:10 [C] B:244 [ARG] D:35 [U] ❌ 6OZP_B_C,D
A:709 [LYS] B:10 [C] B:155 [LYS] D:35 [U] ❌ 4Z4D_A_B,D
A:756 [ILE] B:6 [A] B:203 [SER] C:19 [G] ❌ 4Z4D_A_B,D
A:804 [TYR] B:3 [C] B:237 [ARG] C:16 [C] ❌ 4Z4D_A_B,D
A:811 [PHE] B:3 [C] B:244 [ARG] C:16 [C] ❌ 4Z4D_A_B,D
A:815 [TYR] B:3 [C] B:248 [ARG] C:16 [C] ❌ 4Z4D_A_B,D
A:602 [PRO] D:23 [A] B:57 [LYS] D:37 [U] ❌ 4Z4D_A_B,D
A:756 [ILE] D:27 [U] B:203 [SER] D:41 [U] ❌ 6OZP_D:41 no longer at interface
A:756 [ILE] D:28 [G] B:203 [SER] D:42 [G] ❌ 6OZP_D:42 no longer at interface
A:635 [ARG] B:10 [C] B:90 [PRO] D:35 [U] ❌ 6OZP_D:35 no longer at interface
A:812 [ARG] B:1 [U] B:245 [GLU] C:14 [U] ❌ 6OZP_B:245 no longer at interface
A:754 [ALA] B:5 [C] B:201 [ASP] C:18 [U] ❌ 6OZP_B:201 no longer at interface
A:601 [PRO] B:10 [C] B:56 [VAL] D:35 [U] ❌ 6OZP_D:35 no longer at interface
A:753 [HIS] B:5 [C] B:200 [HIS] C:18 [U] ❌ 6OZP_B:200 no longer at interface
A:753 [HIS] B:6 [A] B:200 [HIS] C:19 [G] ❌ 6OZP_B:200 no longer at interface
A:714 [ARG] B:7 [U] B:170 [LYS] C:20 [C] ❌ 6OZP_B:170 no longer at interface
A:799 [ILE] B:5 [C] B:232 [ILE] C:18 [U] ❌ 6OZP_B:232 no longer at interface
A:638 [ILE] B:10 [C] B:100 [GLU] D:35 [U] ❌ 4Z4D_A:638 no longer at interface
A:669 [ASP] B:10 [C] B:126 [ASP] D:35 [U] ❌ 4Z4D_A:669 no longer at interface
A:807 [HIS] B:10 [C] B:240 [ASP] D:35 [U] ❌ 4Z4D_A:807 no longer at interface
A:808 [LEU] B:3 [C] B:241 [ILE] C:16 [C] ❌ 4Z4D_A:808 no longer at interface
A:808 [LEU] B:4 [A] B:241 [ILE] C:17 [A] ❌ 4Z4D_A:808 no longer at interface
A:597 [ASP] B:10 [C] B:52 [ASP] D:35 [U] ❌ 4Z4D_A:597 no longer at interface

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Properties of this pair

Common ECOD label(s)
Common RFAM label(s)
Interface TM-score
Interface RMSD
Percentage identity
Protein TM-score
RNA TM-score
Protein coverage
RNA coverage
Percentage conservation
Apolar conservation
H-bond conservation
Percentage switching out
Ribonuclease H-like 0.63 2.69 0.10 0.64 0.38 0.75 0.83 0.48 0.42 0.14 0.52


Other pairs involving 4Z4D_A_B,D or 6OZP_B_C,D

Total number of entries: 31

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
4OLA_A_B 6OZP_B_C,D 0.50 0.6 2.63 0.05 Ribonuclease H-like compare
4OLA_A_B 4Z4D_A_B,D 0.95 0.93 3.04 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6OZP_B_C,D 6OZS_A_C,D 0.96 0.94 0.45 0.73 Ribonuclease H-like compare
6OZP_B_C,D 6OZS_B_C,D 0.97 1.0 0.24 1.0 Ribonuclease H-like compare
6MFN_A_C,E 6OZP_B_C,D 0.47 0.63 2.56 0.05 Ribonuclease H-like compare
4KXT_A_B 6OZP_B_C,D 0.48 0.61 2.62 0.05 Ribonuclease H-like compare
4KXT_A_B 4Z4D_A_B,D 0.87 0.91 2.97 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 6OZP_B_C,D 0.54 0.62 2.51 0.05 Ribonuclease H-like compare
4KRE_A_R 4Z4D_A_B,D 0.86 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OZP_B_C,D 0.50 0.61 2.67 0.05 Ribonuclease H-like compare
6OON_A_B 6OZP_B_C,D 0.49 0.61 2.62 0.05 Ribonuclease H-like compare
4Z4D_A_B,D 6MFN_A_C,E 0.85 0.92 1.69 0.76 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5AWH_A_C 0.59 0.71 4.13 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OZS_B_C,D 0.49 0.63 2.83 0.14 Ribonuclease H-like compare
4Z4D_A_B,D 6D92_A_C 0.59 0.71 4.22 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OON_A_B 0.90 0.96 1.83 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6CBD_A_B,C 0.95 1.0 0.3 0.93 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OZP_A_C,D 0.56 0.61 2.76 0.15 Ribonuclease H-like compare
4Z4D_A_B,D 5JS1_A_B 0.90 0.92 3.21 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OZS_A_C,D 0.58 0.6 2.77 0.15 Ribonuclease H-like compare
4Z4D_A_B,D 6OZP_B_C,D 0.48 0.63 2.69 0.1 Ribonuclease H-like compare
4W5O_A_B,D 4Z4D_A_B,D 0.96 1.0 0.12 0.96 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6OZP_B_C,D 0.48 0.63 2.71 0.1 Ribonuclease H-like compare
4KRF_A_R 6OZP_B_C,D 0.53 0.62 2.61 0.05 Ribonuclease H-like compare
4KRF_A_R 4Z4D_A_B,D 0.88 0.93 2.36 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OZP_B_C,D 0.37 0.63 2.75 0.05 Ribonuclease H-like compare
4W5T_A_B,D 4Z4D_A_B,D 0.91 0.99 0.27 0.88 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6OZP_B_C,D 0.53 0.61 2.72 0.05 Ribonuclease H-like compare
4F3T_A_R 4Z4D_A_B,D 0.70 0.92 3.19 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6OZP_B_C,D 0.48 0.63 2.7 0.1 Ribonuclease H-like compare