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All interfaces > All interologs > Interface groups > group140 > 5I4A_A_B

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Licorice
Surface

RNA

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Licorice
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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

5I4A_A
5I4A_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:31 [ARG] B:20 [U] 3.27 68.96
A:31 [ARG] B:21 [U] 3.54 68.96
A:82 [LYS] B:12 [C] 4.43 58.06
A:85 [VAL] B:11 [A] 4.19 44.76
A:86 [LYS] B:11 [A] 4.04 86.56
A:89 [TYR] B:11 [A] 3.2 base/AA stacks 86.87
A:90 [LYS] B:11 [A] 3.66 68.69
A:103 [PHE] B:11 [A] 4.81 53.91
A:104 [LYS] B:7 [A] 4.56 60.28
A:104 [LYS] B:8 [C] 3.33 60.28
A:105 [LYS] B:8 [C] 2.33 sugar:BB 66.24
A:105 [LYS] B:9 [C] 4.29 66.24
A:106 [GLY] B:8 [C] 4.16 61.65
A:106 [GLY] B:9 [C] 3.57 61.65
A:106 [GLY] B:10 [U] 4.82 61.65
A:107 [ASN] B:11 [A] 2.65 base:SC, base:SC 85.78
A:108 [ASN] B:8 [C] 3.54 52.09
A:108 [ASN] B:9 [C] 3.2 52.09
A:131 [LYS] B:8 [C] 4.8 70.89
A:131 [LYS] B:9 [C] 2.79 70.89
A:131 [LYS] B:10 [U] 3.05 70.89
A:133 [LYS] B:9 [C] 4.7 80.22
A:133 [LYS] B:10 [U] 3.36 80.22
A:133 [LYS] B:11 [A] 2.83 80.22
A:134 [ILE] B:11 [A] 4.52 67.0
A:148 [LYS] B:9 [C] 3.55 76.37
A:166 [TYR] B:7 [A] 4.22 69.74
A:169 [ASN] B:20 [U] 3.19 98.31
A:171 [LYS] B:20 [U] 3.45 76.96
A:172 [SER] B:20 [U] 3.19 87.34
A:174 [LYS] B:20 [U] 4.69 91.46
A:175 [SER] B:8 [C] 4.94 87.34
A:176 [PHE] B:20 [U] 3.47 87.42
A:188 [ILE] B:21 [U] 3.95 98.17
A:190 [ILE] B:21 [U] 3.77 59.05
A:196 [VAL] B:21 [U] 4.32 58.76
A:198 [VAL] B:21 [U] 3.37 98.01
A:199 [ALA] B:21 [U] 2.92 sugar:BB 45.62
A:200 [TYR] B:21 [U] 3.78 19.93
A:203 [ASN] B:20 [U] 3.9 sugar:SC 81.69
A:204 [TYR] B:20 [U] 4.16 93.62
A:204 [TYR] B:21 [U] 3.3 base:SC 93.62
A:207 [ASN] B:7 [A] 3.82 sugar:SC 94.98
A:209 [THR] B:6 [A] 4.52 79.17
A:209 [THR] B:7 [A] 2.71 79.17
A:210 [THR] B:6 [A] 4.65 75.16
A:210 [THR] B:7 [A] 2.88 75.16
A:211 [ARG] B:5 [C] 2.62 base:SC 39.08
A:211 [ARG] B:6 [A] 3.56 39.08
A:211 [ARG] B:7 [A] 3.26 39.08
A:376 [LEU] B:1 [U] 3.54 94.26
A:378 [LYS] B:1 [U] 4.32 46.26
A:379 [TYR] B:1 [U] 3.18 base/AA stacks 14.23
A:379 [TYR] B:4 [A] 4.8 14.23
A:379 [TYR] B:5 [C] 3.69 14.23
A:380 [ILE] B:1 [U] 2.77 base:BB, base:BB 38.58
A:381 [GLY] B:1 [U] 4.34 61.66
A:383 [ILE] B:1 [U] 3.61 87.22
A:398 [PRO] B:1 [U] 3.64 95.02
A:398 [PRO] B:2 [A] 3.46 95.02
A:399 [ILE] B:1 [U] 3.92 81.74
A:399 [ILE] B:2 [A] 3.32 81.74
A:400 [LEU] B:1 [U] 3.83 87.75
A:400 [LEU] B:2 [A] 2.61 87.75
A:403 [LYS] B:2 [A] 2.76 base:SC 79.33
A:403 [LYS] B:3 [U] 4.21 79.33
A:410 [PHE] B:2 [A] 3.57 72.15
A:411 [ILE] B:2 [A] 3.79 77.86
A:414 [SER] B:2 [A] 3.16 98.82
A:415 [TYR] B:2 [A] 3.77 77.75
A:418 [LYS] B:1 [U] 3.85 96.31
A:418 [LYS] B:2 [A] 3.32 96.31
A:418 [LYS] B:3 [U] 2.47 96.31
A:518 [ARG] B:10 [U] 3.16 50.13
A:518 [ARG] B:11 [A] 3.24 50.13
A:518 [ARG] B:12 [C] 2.48 50.13
A:545 [ASN] B:10 [U] 3.51 80.23
A:573 [PHE] B:4 [A] 3.44 58.61
A:574 [LEU] B:4 [A] 3.87 72.07
A:574 [LEU] B:5 [C] 3.69 72.07
A:574 [LEU] B:6 [A] 4.75 72.07
A:608 [SER] B:3 [U] 3.22 77.11
A:608 [SER] B:4 [A] 4.12 77.11
A:609 [THR] B:2 [A] 3.91 90.98
A:609 [THR] B:3 [U] 3.0 sugar:SC 90.98
A:611 [TYR] B:2 [A] 4.76 86.92
A:612 [THR] B:3 [U] 2.44 sugar:SC 57.84
A:612 [THR] B:4 [A] 3.81 57.84
A:614 [TYR] B:4 [A] 4.08 69.14
A:615 [LYS] B:4 [A] 3.6 73.48
A:615 [LYS] B:5 [C] 2.35 73.48
A:621 [HIS] B:4 [A] 4.84 75.47
A:625 [LYS] B:4 [A] 4.74 96.31
A:632 [GLU] B:1 [U] 3.94 83.16
A:635 [LEU] B:1 [U] 4.53 65.02
A:635 [LEU] B:3 [U] 4.02 65.02
A:636 [TYR] B:1 [U] 3.19 87.08
A:636 [TYR] B:3 [U] 3.77 87.08

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group140 5I4A_A_B A: Argonaute protein, Marinitoga piezophila (strain dsm 14283 / jcm 11233 / ka3) (genetically engineered) B: Synthetic construct (synthetic) H2J4R4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs ✘

Interologs

Total number of interologs for this interface: 11

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare