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All interfaces > All interologs > Interface groups > group140 > 5I4A_A_B vs 5JS1_A_B

Interface analysis


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Common contacts -

5I4A_A
5I4A_B
5JS1_A
5JS1_B
Conserved?
A:403 [LYS] B:2 [A] A:551 [ASN] B:2 [U] ✔
A:410 [PHE] B:2 [A] A:558 [GLN] B:2 [U] ✔
A:414 [SER] B:2 [A] A:562 [ASN] B:2 [U] ✔
A:376 [LEU] B:1 [U] A:522 [LEU] B:1 [U] ✔
A:614 [TYR] B:4 [A] A:797 [VAL] B:4 [U] ✔
A:398 [PRO] B:1 [U] A:546 [CYS] B:1 [U] ✔
A:398 [PRO] B:2 [A] A:546 [CYS] B:2 [U] ✔
A:621 [HIS] B:4 [A] A:804 [TYR] B:4 [U] ✔
A:609 [THR] B:3 [U] A:793 [CYS] B:3 [A] ✔
A:632 [GLU] B:1 [U] A:815 [TYR] B:1 [U] ✔
A:383 [ILE] B:1 [U] A:529 [TYR] B:1 [U] ✔
A:380 [ILE] B:1 [U] A:526 [THR] B:1 [U] ✔
A:615 [LYS] B:4 [A] A:798 [SER] B:4 [U] ✔
A:612 [THR] B:4 [A] A:795 [ARG] B:4 [U] ✔
A:399 [ILE] B:1 [U] A:547 [VAL] B:1 [U] ✔
A:399 [ILE] B:2 [A] A:547 [VAL] B:2 [U] ✔
A:411 [ILE] B:2 [A] A:559 [THR] B:2 [U] ✔
A:379 [TYR] B:1 [U] A:525 [LYS] B:1 [U] ✔
A:415 [TYR] B:2 [A] A:563 [LEU] B:2 [U] ✔
A:418 [LYS] B:1 [U] A:566 [LYS] B:1 [U] ✔
A:418 [LYS] B:2 [A] A:566 [LYS] B:2 [U] ✔
A:418 [LYS] B:3 [U] A:566 [LYS] B:3 [A] ✔
A:608 [SER] B:3 [U] A:792 [ARG] B:3 [A] ✔
A:608 [SER] B:4 [A] A:792 [ARG] B:4 [U] ✔
A:573 [PHE] B:4 [A] A:756 [ILE] B:4 [U] ✔
A:400 [LEU] B:1 [U] A:548 [GLN] B:1 [U] ✔
A:400 [LEU] B:2 [A] A:548 [GLN] B:2 [U] ✔
A:378 [LYS] B:1 [U] A:524 [GLY] B:1 [U] ✔
A:403 [LYS] B:3 [U] A:551 [ASN] B:3 [A] ❌ 5JS1_A_B
A:104 [LYS] B:8 [C] A:177 [VAL] B:8 [U] ❌ 5JS1_A_B
A:609 [THR] B:2 [A] A:793 [CYS] B:2 [U] ❌ 5JS1_A_B
A:148 [LYS] B:9 [C] A:220 [SER] B:9 [A] ❌ 5JS1_A_B
A:612 [THR] B:3 [U] A:795 [ARG] B:3 [A] ❌ 5JS1_A_B
A:574 [LEU] B:4 [A] A:757 [GLN] B:4 [U] ❌ 5JS1_A_B
A:379 [TYR] B:4 [A] A:525 [LYS] B:4 [U] ❌ 5JS1_A_B
A:104 [LYS] B:9 [C] A:177 [VAL] B:9 [A] ❌ 5I4A_A_B
A:148 [LYS] B:8 [C] A:220 [SER] B:8 [U] ❌ 5I4A_A_B
A:207 [ASN] B:8 [C] A:352 [CYS] B:8 [U] ❌ 5I4A_A_B
A:414 [SER] B:3 [U] A:562 [ASN] B:3 [A] ❌ 5I4A_A_B
A:545 [ASN] B:9 [C] A:710 [ARG] B:9 [A] ❌ 5I4A_A_B
A:609 [THR] B:4 [A] A:793 [CYS] B:4 [U] ❌ 5I4A_A_B
A:175 [SER] B:8 [C] A:280 [ARG] B:8 [U] ❌ 5JS1_A:280 no longer at interface
A:106 [GLY] B:8 [C] A:178 [GLY] B:8 [U] ❌ 5JS1_A:178 no longer at interface
A:106 [GLY] B:9 [C] A:178 [GLY] B:9 [A] ❌ 5JS1_A:178 no longer at interface
A:635 [LEU] B:1 [U] A:852 [THR] B:1 [U] ❌ 5JS1_A:852 no longer at interface
A:635 [LEU] B:3 [U] A:852 [THR] B:3 [A] ❌ 5JS1_A:852 no longer at interface
A:108 [ASN] B:8 [C] A:180 [SER] B:8 [U] ❌ 5JS1_A:180 no longer at interface
A:108 [ASN] B:9 [C] A:180 [SER] B:9 [A] ❌ 5JS1_A:180 no longer at interface
A:131 [LYS] B:8 [C] A:203 [HIS] B:8 [U] ❌ 5JS1_A:203 no longer at interface
A:131 [LYS] B:9 [C] A:203 [HIS] B:9 [A] ❌ 5JS1_A:203 no longer at interface
A:625 [LYS] B:4 [A] A:808 [LEU] B:4 [U] ❌ 5JS1_A:808 no longer at interface
A:636 [TYR] B:1 [U] A:855 [THR] B:1 [U] ❌ 5JS1_A:855 no longer at interface
A:636 [TYR] B:3 [U] A:855 [THR] B:3 [A] ❌ 5JS1_A:855 no longer at interface
A:133 [LYS] B:9 [C] A:205 [SER] B:9 [A] ❌ 5JS1_A:205 no longer at interface
A:381 [GLY] B:1 [U] A:527 [PRO] B:1 [U] ❌ 5JS1_A:527 no longer at interface
A:147 [PRO] B:8 [C] A:219 [VAL] B:8 [U] ❌ 5I4A_A:147 no longer at interface
A:149 [PHE] B:8 [C] A:221 [ALA] B:8 [U] ❌ 5I4A_A:149 no longer at interface
A:150 [THR] B:8 [C] A:222 [THR] B:8 [U] ❌ 5I4A_A:150 no longer at interface
A:150 [THR] B:9 [C] A:222 [THR] B:9 [A] ❌ 5I4A_A:150 no longer at interface
A:151 [PHE] B:8 [C] A:223 [ALA] B:8 [U] ❌ 5I4A_A:151 no longer at interface
A:206 [PHE] B:9 [C] A:351 [ARG] B:9 [A] ❌ 5I4A_A:206 no longer at interface
A:208 [PHE] B:9 [C] A:353 [ILE] B:9 [A] ❌ 5I4A_A:208 no longer at interface
A:219 [SER] B:8 [C] A:364 [MET] B:8 [U] ❌ 5I4A_A:219 no longer at interface
A:387 [VAL] B:1 [U] A:533 [LYS] B:1 [U] ❌ 5I4A_A:387 no longer at interface
A:396 [LEU] B:1 [U] A:544 [THR] B:1 [U] ❌ 5I4A_A:396 no longer at interface
A:397 [GLN] B:2 [A] A:545 [GLN] B:2 [U] ❌ 5I4A_A:397 no longer at interface
A:397 [GLN] B:1 [U] A:545 [GLN] B:1 [U] ❌ 5I4A_A:397 no longer at interface
A:422 [PHE] B:1 [U] A:570 [LYS] B:1 [U] ❌ 5I4A_A:422 no longer at interface
A:547 [ASN] B:8 [C] A:712 [HIS] B:8 [U] ❌ 5I4A_A:547 no longer at interface
A:549 [ASN] B:8 [C] A:714 [ARG] B:8 [U] ❌ 5I4A_A:549 no longer at interface
A:577 [LYS] B:8 [C] A:761 [ARG] B:8 [U] ❌ 5I4A_A:577 no longer at interface
A:606 [ALA] B:3 [U] A:790 [TYR] B:3 [A] ❌ 5I4A_A:606 no longer at interface
A:606 [ALA] B:4 [A] A:790 [TYR] B:4 [U] ❌ 5I4A_A:606 no longer at interface
A:629 [THR] B:1 [U] A:812 [ARG] B:1 [U] ❌ 5I4A_A:629 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.77 3.53 0.03 0.77 0.3 0.45 0.6 0.60 0.61 0.15 0.72


Other pairs involving 5I4A_A_B or 5JS1_A_B

Total number of entries: 28

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 5JS1_A_B 0.99 1.0 0.31 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 5JS1_A_B 0.97 0.98 0.84 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5JS1_A_B 0.98 0.97 1.31 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6MFN_A_C,E 0.86 0.86 1.83 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
5JS1_A_B 6OZS_B_C,D 0.52 0.61 2.68 0.0 Ribonuclease H-like compare
5JS1_A_B 6OZS_A_C,D 0.58 0.61 2.63 0.0 Ribonuclease H-like compare
5JS1_A_B 6D92_A_C 0.60 0.71 3.43 0.15 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6CBD_A_B,C 0.91 0.91 3.24 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OON_A_B 0.98 0.96 1.74 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OZP_B_C,D 0.50 0.61 2.67 0.05 Ribonuclease H-like compare
5JS1_A_B 6OZP_A_C,D 0.58 0.61 2.68 0.1 Ribonuclease H-like compare
5AWH_A_C 5JS1_A_B 0.62 0.71 4.1 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5JS1_A_B 0.90 0.92 3.21 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5JS1_A_B 0.88 0.92 3.24 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5JS1_A_B 0.98 0.98 1.05 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5JS1_A_B 0.87 0.92 3.34 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5JS1_A_B 0.98 0.99 0.4 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare