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All interfaces > All interologs > Interface groups > group140 > 5I4A_A_B vs 6CBD_A_B,C

Interface analysis


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Common contacts -

5I4A_A
5I4A_B
6CBD_A
6CBD_B,C
Conserved?
A:403 [LYS] B:2 [A] A:551 [ASN] B:2 [U] ✔
A:410 [PHE] B:2 [A] A:558 [GLN] B:2 [U] ✔
A:414 [SER] B:2 [A] A:562 [ASN] B:2 [U] ✔
A:376 [LEU] B:1 [U] A:522 [LEU] B:1 [U] ✔
A:614 [TYR] B:4 [A] A:797 [VAL] B:4 [A] ✔
A:398 [PRO] B:1 [U] A:546 [CYS] B:1 [U] ✔
A:398 [PRO] B:2 [A] A:546 [CYS] B:2 [U] ✔
A:621 [HIS] B:4 [A] A:804 [TYR] B:4 [A] ✔
A:609 [THR] B:3 [U] A:793 [CYS] B:3 [C] ✔
A:632 [GLU] B:1 [U] A:815 [TYR] B:1 [U] ✔
A:383 [ILE] B:1 [U] A:529 [TYR] B:1 [U] ✔
A:380 [ILE] B:1 [U] A:526 [THR] B:1 [U] ✔
A:615 [LYS] B:4 [A] A:798 [SER] B:4 [A] ✔
A:612 [THR] B:4 [A] A:795 [ARG] B:4 [A] ✔
A:399 [ILE] B:1 [U] A:547 [VAL] B:1 [U] ✔
A:399 [ILE] B:2 [A] A:547 [VAL] B:2 [U] ✔
A:411 [ILE] B:2 [A] A:559 [THR] B:2 [U] ✔
A:379 [TYR] B:1 [U] A:525 [LYS] B:1 [U] ✔
A:415 [TYR] B:2 [A] A:563 [LEU] B:2 [U] ✔
A:418 [LYS] B:1 [U] A:566 [LYS] B:1 [U] ✔
A:418 [LYS] B:2 [A] A:566 [LYS] B:2 [U] ✔
A:418 [LYS] B:3 [U] A:566 [LYS] B:3 [C] ✔
A:107 [ASN] B:11 [A] A:179 [ARG] B:12 [C] ✔
A:518 [ARG] B:11 [A] A:672 [SER] B:12 [C] ✔
A:608 [SER] B:3 [U] A:792 [ARG] B:3 [C] ✔
A:608 [SER] B:4 [A] A:792 [ARG] B:4 [A] ✔
A:573 [PHE] B:4 [A] A:756 [ILE] B:4 [A] ✔
A:400 [LEU] B:1 [U] A:548 [GLN] B:1 [U] ✔
A:400 [LEU] B:2 [A] A:548 [GLN] B:2 [U] ✔
A:378 [LYS] B:1 [U] A:524 [GLY] B:1 [U] ✔
A:403 [LYS] B:3 [U] A:551 [ASN] B:3 [C] ❌ 6CBD_A_B,C
A:104 [LYS] B:7 [A] A:177 [VAL] B:8 [U] ❌ 6CBD_A_B,C
A:104 [LYS] B:8 [C] A:177 [VAL] B:9 [G] ❌ 6CBD_A_B,C
A:609 [THR] B:2 [A] A:793 [CYS] B:2 [U] ❌ 6CBD_A_B,C
A:148 [LYS] B:9 [C] A:220 [SER] B:10 [C] ❌ 6CBD_A_B,C
A:612 [THR] B:3 [U] A:795 [ARG] B:3 [C] ❌ 6CBD_A_B,C
A:574 [LEU] B:4 [A] A:757 [GLN] B:4 [A] ❌ 6CBD_A_B,C
A:379 [TYR] B:4 [A] A:525 [LYS] B:4 [A] ❌ 6CBD_A_B,C
A:518 [ARG] B:12 [C] A:672 [SER] B:14 [A] ❌ 6CBD_A_B,C
A:105 [LYS] B:8 [C] A:178 [GLY] B:9 [G] ❌ 6CBD_A_B,C
A:105 [LYS] B:9 [C] A:178 [GLY] B:10 [C] ❌ 6CBD_A_B,C
A:103 [PHE] B:11 [A] A:176 [PRO] B:12 [C] ❌ 6CBD_A_B,C
A:103 [PHE] B:12 [C] A:176 [PRO] B:14 [A] ❌ 5I4A_A_B
A:104 [LYS] B:12 [C] A:177 [VAL] B:14 [A] ❌ 5I4A_A_B
A:105 [LYS] B:12 [C] A:178 [GLY] B:14 [A] ❌ 5I4A_A_B
A:148 [LYS] B:7 [A] A:220 [SER] B:8 [U] ❌ 5I4A_A_B
A:403 [LYS] B:1 [U] A:551 [ASN] B:1 [U] ❌ 5I4A_A_B
A:414 [SER] B:3 [U] A:562 [ASN] B:3 [C] ❌ 5I4A_A_B
A:545 [ASN] B:7 [A] A:710 [ARG] B:8 [U] ❌ 5I4A_A_B
A:545 [ASN] B:8 [C] A:710 [ARG] B:9 [G] ❌ 5I4A_A_B
A:545 [ASN] B:9 [C] A:710 [ARG] B:10 [C] ❌ 5I4A_A_B
A:609 [THR] B:4 [A] A:793 [CYS] B:4 [A] ❌ 5I4A_A_B
A:82 [LYS] B:12 [C] A:156 [PHE] B:14 [A] ❌ 6CBD_A:156 no longer at interface
A:85 [VAL] B:11 [A] A:159 [ILE] B:12 [C] ❌ 6CBD_A:159 no longer at interface
A:200 [TYR] B:21 [U] A:345 [ASN] B:17 [C] ❌ 6CBD_A:345 no longer at interface
A:89 [TYR] B:11 [A] A:163 [ASP] B:12 [C] ❌ 6CBD_A:163 no longer at interface
A:209 [THR] B:7 [A] A:354 [LYS] B:8 [U] ❌ 6CBD_A:354 no longer at interface
A:207 [ASN] B:7 [A] A:352 [CYS] B:8 [U] ❌ 6CBD_A:352 no longer at interface
A:196 [VAL] B:21 [U] A:282 [CYS] B:17 [C] ❌ 6CBD_A:282 no longer at interface
A:86 [LYS] B:11 [A] A:160 [GLN] B:12 [C] ❌ 6CBD_A:160 no longer at interface
A:210 [THR] B:7 [A] A:355 [LYS] B:8 [U] ❌ 6CBD_A:355 no longer at interface
A:204 [TYR] B:20 [U] A:349 [GLY] B:16 [U] ❌ 6CBD_A:349 no longer at interface
A:204 [TYR] B:21 [U] A:349 [GLY] B:17 [C] ❌ 6CBD_A:349 no longer at interface
A:198 [VAL] B:21 [U] A:329 [GLN] B:17 [C] ❌ 6CBD_A:329 no longer at interface
A:90 [LYS] B:11 [A] A:164 [VAL] B:12 [C] ❌ 6CBD_A:164 no longer at interface
A:188 [ILE] B:21 [U] A:264 [GLY] B:17 [C] ❌ 6CBD_A:264 no longer at interface
A:199 [ALA] B:21 [U] A:330 [VAL] B:17 [C] ❌ 6CBD_A:330 no longer at interface
A:635 [LEU] B:1 [U] A:852 [THR] B:1 [U] ❌ 6CBD_A:852 no longer at interface
A:635 [LEU] B:3 [U] A:852 [THR] B:3 [C] ❌ 6CBD_A:852 no longer at interface
A:108 [ASN] B:8 [C] A:180 [SER] B:9 [G] ❌ 6CBD_A:180 no longer at interface
A:108 [ASN] B:9 [C] A:180 [SER] B:10 [C] ❌ 6CBD_A:180 no longer at interface
A:131 [LYS] B:8 [C] A:203 [HIS] B:9 [G] ❌ 6CBD_A:203 no longer at interface
A:131 [LYS] B:9 [C] A:203 [HIS] B:10 [C] ❌ 6CBD_A:203 no longer at interface
A:625 [LYS] B:4 [A] A:808 [LEU] B:4 [A] ❌ 6CBD_A:808 no longer at interface
A:211 [ARG] B:7 [A] A:356 [LEU] B:8 [U] ❌ 6CBD_A:356 no longer at interface
A:636 [TYR] B:1 [U] A:855 [THR] B:1 [U] ❌ 6CBD_A:855 no longer at interface
A:636 [TYR] B:3 [U] A:855 [THR] B:3 [C] ❌ 6CBD_A:855 no longer at interface
A:133 [LYS] B:9 [C] A:205 [SER] B:10 [C] ❌ 6CBD_A:205 no longer at interface
A:133 [LYS] B:11 [A] A:205 [SER] B:12 [C] ❌ 6CBD_A:205 no longer at interface
A:203 [ASN] B:20 [U] A:348 [ALA] B:16 [U] ❌ 6CBD_A:348 no longer at interface
A:31 [ARG] B:20 [U] A:69 [ARG] B:16 [U] ❌ 6CBD_A:69 no longer at interface
A:31 [ARG] B:21 [U] A:69 [ARG] B:17 [C] ❌ 6CBD_A:69 no longer at interface
A:134 [ILE] B:11 [A] A:206 [VAL] B:12 [C] ❌ 6CBD_A:206 no longer at interface
A:381 [GLY] B:1 [U] A:527 [PRO] B:1 [U] ❌ 6CBD_A:527 no longer at interface
A:149 [PHE] B:7 [A] A:221 [ALA] B:8 [U] ❌ 5I4A_A:149 no longer at interface
A:206 [PHE] B:8 [C] A:351 [ARG] B:9 [G] ❌ 5I4A_A:206 no longer at interface
A:387 [VAL] B:1 [U] A:533 [LYS] B:1 [U] ❌ 5I4A_A:387 no longer at interface
A:396 [LEU] B:1 [U] A:544 [THR] B:1 [U] ❌ 5I4A_A:396 no longer at interface
A:397 [GLN] B:2 [A] A:545 [GLN] B:2 [U] ❌ 5I4A_A:397 no longer at interface
A:397 [GLN] B:1 [U] A:545 [GLN] B:1 [U] ❌ 5I4A_A:397 no longer at interface
A:422 [PHE] B:1 [U] A:570 [LYS] B:1 [U] ❌ 5I4A_A:422 no longer at interface
A:447 [LEU] B:9 [C] A:598 [VAL] B:10 [C] ❌ 5I4A_A:447 no longer at interface
A:448 [SER] B:9 [C] A:599 [THR] B:10 [C] ❌ 5I4A_A:448 no longer at interface
A:449 [HIS] B:9 [C] A:600 [HIS] B:10 [C] ❌ 5I4A_A:449 no longer at interface
A:450 [ASP] B:9 [C] A:601 [PRO] B:10 [C] ❌ 5I4A_A:450 no longer at interface
A:480 [LEU] B:9 [C] A:635 [ARG] B:10 [C] ❌ 5I4A_A:480 no longer at interface
A:27 [LYS] B:21 [U] A:65 [LYS] B:17 [C] ❌ 5I4A_A:27 no longer at interface
A:27 [LYS] B:20 [U] A:65 [LYS] B:16 [U] ❌ 5I4A_A:27 no longer at interface
A:28 [LEU] B:21 [U] A:66 [CYS] B:17 [C] ❌ 5I4A_A:28 no longer at interface
A:29 [PHE] B:21 [U] A:67 [PRO] B:17 [C] ❌ 5I4A_A:29 no longer at interface
A:29 [PHE] B:20 [U] A:67 [PRO] B:16 [U] ❌ 5I4A_A:29 no longer at interface
A:30 [ALA] B:20 [U] A:68 [ARG] B:16 [U] ❌ 5I4A_A:30 no longer at interface
A:30 [ALA] B:12 [C] A:68 [ARG] B:14 [A] ❌ 5I4A_A:30 no longer at interface
A:32 [ASN] B:21 [U] A:70 [VAL] B:17 [C] ❌ 5I4A_A:32 no longer at interface
A:577 [LYS] B:7 [A] A:761 [ARG] B:8 [U] ❌ 5I4A_A:577 no longer at interface
A:606 [ALA] B:4 [A] A:790 [TYR] B:4 [A] ❌ 5I4A_A:606 no longer at interface
A:606 [ALA] B:3 [U] A:790 [TYR] B:3 [C] ❌ 5I4A_A:606 no longer at interface
A:628 [LEU] B:9 [C] A:811 [PHE] B:10 [C] ❌ 5I4A_A:628 no longer at interface
A:629 [THR] B:1 [U] A:812 [ARG] B:1 [U] ❌ 5I4A_A:629 no longer at interface
A:42 [GLN] B:12 [C] A:97 [ARG] B:14 [A] ❌ 5I4A_A:42 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.78 2.46 0.03 0.78 0.23 0.46 0.79 0.39 0.42 0.12 0.72


Other pairs involving 5I4A_A_B or 6CBD_A_B,C

Total number of entries: 28

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6CBD_A_B,C 0.95 0.91 3.17 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 6CBD_A_B,C 0.91 0.9 2.96 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 6CBD_A_B,C 0.86 0.93 2.27 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6CBD_A_B,C 0.91 0.91 3.24 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6CBD_A_B,C 0.59 0.71 3.34 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6CBD_A_B,C 0.95 1.0 0.3 0.93 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6CBD_A_B,C 0.99 1.0 0.36 0.97 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 6CBD_A_B,C 0.86 0.93 2.39 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6CBD_A_B,C 0.94 0.99 0.4 0.88 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6CBD_A_B,C 0.79 0.91 3.2 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6OZP_A_C,D 0.54 0.61 2.77 0.15 Ribonuclease H-like compare
6CBD_A_B,C 6OZS_B_C,D 0.49 0.63 2.82 0.14 Ribonuclease H-like compare
6CBD_A_B,C 6OZS_A_C,D 0.43 0.61 2.77 0.15 Ribonuclease H-like compare
6CBD_A_B,C 6OON_A_B 0.90 0.95 1.87 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6D92_A_C 0.57 0.71 3.31 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6OZP_B_C,D 0.48 0.63 2.7 0.1 Ribonuclease H-like compare
6CBD_A_B,C 6MFN_A_C,E 0.83 0.92 1.43 0.76 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare