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All interfaces > All interologs > Interface groups > group140 > 5I4A_A_B vs 6OON_A_B

Interface analysis


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Common contacts -

5I4A_A
5I4A_B
6OON_A
6OON_B
Conserved?
A:403 [LYS] B:2 [A] A:543 [ASN] B:2 [A]
A:410 [PHE] B:2 [A] A:550 [GLN] B:2 [A]
A:414 [SER] B:2 [A] A:554 [ASN] B:2 [A]
A:376 [LEU] B:1 [U] A:514 [LEU] B:1 [A]
A:614 [TYR] B:4 [A] A:799 [VAL] B:4 [A]
A:398 [PRO] B:1 [U] A:538 [CYS] B:1 [A]
A:398 [PRO] B:2 [A] A:538 [CYS] B:2 [A]
A:621 [HIS] B:4 [A] A:806 [TYR] B:4 [A]
A:609 [THR] B:3 [U] A:795 [CYS] B:3 [A]
A:632 [GLU] B:1 [U] A:817 [TYR] B:1 [A]
A:383 [ILE] B:1 [U] A:521 [TYR] B:1 [A]
A:380 [ILE] B:1 [U] A:518 [THR] B:1 [A]
A:615 [LYS] B:4 [A] A:800 [SER] B:4 [A]
A:612 [THR] B:3 [U] A:797 [ARG] B:3 [A]
A:612 [THR] B:4 [A] A:797 [ARG] B:4 [A]
A:399 [ILE] B:1 [U] A:539 [VAL] B:1 [A]
A:399 [ILE] B:2 [A] A:539 [VAL] B:2 [A]
A:411 [ILE] B:2 [A] A:551 [THR] B:2 [A]
A:379 [TYR] B:1 [U] A:517 [LYS] B:1 [A]
A:415 [TYR] B:2 [A] A:555 [LEU] B:2 [A]
A:418 [LYS] B:1 [U] A:558 [LYS] B:1 [A]
A:418 [LYS] B:2 [A] A:558 [LYS] B:2 [A]
A:418 [LYS] B:3 [U] A:558 [LYS] B:3 [A]
A:188 [ILE] B:21 [U] A:270 [ARG] B:15 [A]
A:608 [SER] B:3 [U] A:794 [ARG] B:3 [A]
A:608 [SER] B:4 [A] A:794 [ARG] B:4 [A]
A:573 [PHE] B:4 [A] A:758 [ILE] B:4 [A]
A:400 [LEU] B:1 [U] A:540 [GLN] B:1 [A]
A:400 [LEU] B:2 [A] A:540 [GLN] B:2 [A]
A:378 [LYS] B:1 [U] A:516 [GLY] B:1 [A]
A:31 [ARG] B:21 [U] A:59 [ARG] B:15 [A]
A:403 [LYS] B:3 [U] A:543 [ASN] B:3 [A] ❌ 6OON_A_B
A:104 [LYS] B:8 [C] A:167 [VAL] B:8 [A] ❌ 6OON_A_B
A:609 [THR] B:2 [A] A:795 [CYS] B:2 [A] ❌ 6OON_A_B
A:574 [LEU] B:4 [A] A:759 [GLN] B:4 [A] ❌ 6OON_A_B
A:379 [TYR] B:4 [A] A:517 [LYS] B:4 [A] ❌ 6OON_A_B
A:148 [LYS] B:8 [C] A:210 [SER] B:8 [A] ❌ 5I4A_A_B
A:414 [SER] B:3 [U] A:554 [ASN] B:3 [A] ❌ 5I4A_A_B
A:545 [ASN] B:8 [C] A:712 [ARG] B:8 [A] ❌ 5I4A_A_B
A:609 [THR] B:4 [A] A:795 [CYS] B:4 [A] ❌ 5I4A_A_B
A:200 [TYR] B:21 [U] A:335 [ASN] B:15 [A] ❌ 6OON_A:335 no longer at interface
A:196 [VAL] B:21 [U] A:318 [LEU] B:15 [A] ❌ 6OON_A:318 no longer at interface
A:204 [TYR] B:21 [U] A:339 [GLY] B:15 [A] ❌ 6OON_A:339 no longer at interface
A:198 [VAL] B:21 [U] A:320 [VAL] B:15 [A] ❌ 6OON_A:320 no longer at interface
A:199 [ALA] B:21 [U] A:334 [CYS] B:15 [A] ❌ 6OON_A:334 no longer at interface
A:635 [LEU] B:1 [U] A:857 [THR] B:1 [A] ❌ 6OON_A:857 no longer at interface
A:635 [LEU] B:3 [U] A:857 [THR] B:3 [A] ❌ 6OON_A:857 no longer at interface
A:108 [ASN] B:8 [C] A:170 [SER] B:8 [A] ❌ 6OON_A:170 no longer at interface
A:131 [LYS] B:8 [C] A:193 [HIS] B:8 [A] ❌ 6OON_A:193 no longer at interface
A:625 [LYS] B:4 [A] A:810 [LEU] B:4 [A] ❌ 6OON_A:810 no longer at interface
A:105 [LYS] B:8 [C] A:168 [GLY] B:8 [A] ❌ 6OON_A:168 no longer at interface
A:636 [TYR] B:1 [U] A:858 [MET] B:1 [A] ❌ 6OON_A:858 no longer at interface
A:636 [TYR] B:3 [U] A:858 [MET] B:3 [A] ❌ 6OON_A:858 no longer at interface
A:190 [ILE] B:21 [U] A:272 [CYS] B:15 [A] ❌ 6OON_A:272 no longer at interface
A:381 [GLY] B:1 [U] A:519 [PRO] B:1 [A] ❌ 6OON_A:519 no longer at interface
A:147 [PRO] B:8 [C] A:209 [VAL] B:8 [A] ❌ 5I4A_A:147 no longer at interface
A:149 [PHE] B:8 [C] A:211 [ALA] B:8 [A] ❌ 5I4A_A:149 no longer at interface
A:150 [THR] B:8 [C] A:212 [THR] B:8 [A] ❌ 5I4A_A:150 no longer at interface
A:182 [LEU] B:21 [U] A:256 [LYS] B:15 [A] ❌ 5I4A_A:182 no longer at interface
A:219 [SER] B:8 [C] A:354 [MET] B:8 [A] ❌ 5I4A_A:219 no longer at interface
A:387 [VAL] B:1 [U] A:525 [LYS] B:1 [A] ❌ 5I4A_A:387 no longer at interface
A:396 [LEU] B:1 [U] A:536 [THR] B:1 [A] ❌ 5I4A_A:396 no longer at interface
A:397 [GLN] B:1 [U] A:537 [GLN] B:1 [A] ❌ 5I4A_A:397 no longer at interface
A:397 [GLN] B:2 [A] A:537 [GLN] B:2 [A] ❌ 5I4A_A:397 no longer at interface
A:27 [LYS] B:21 [U] A:55 [LYS] B:15 [A] ❌ 5I4A_A:27 no longer at interface
A:28 [LEU] B:21 [U] A:56 [ARG] B:15 [A] ❌ 5I4A_A:28 no longer at interface
A:422 [PHE] B:1 [U] A:562 [LYS] B:1 [A] ❌ 5I4A_A:422 no longer at interface
A:29 [PHE] B:21 [U] A:57 [PRO] B:15 [A] ❌ 5I4A_A:29 no longer at interface
A:32 [ASN] B:21 [U] A:60 [VAL] B:15 [A] ❌ 5I4A_A:32 no longer at interface
A:547 [ASN] B:8 [C] A:714 [HIS] B:8 [A] ❌ 5I4A_A:547 no longer at interface
A:549 [ASN] B:8 [C] A:716 [ARG] B:8 [A] ❌ 5I4A_A:549 no longer at interface
A:577 [LYS] B:8 [C] A:763 [ARG] B:8 [A] ❌ 5I4A_A:577 no longer at interface
A:606 [ALA] B:3 [U] A:792 [TYR] B:3 [A] ❌ 5I4A_A:606 no longer at interface
A:606 [ALA] B:4 [A] A:792 [TYR] B:4 [A] ❌ 5I4A_A:606 no longer at interface
A:629 [THR] B:1 [U] A:814 [ARG] B:1 [A] ❌ 5I4A_A:629 no longer at interface
A:639 [TYR] B:1 [U] A:861 [ALA] B:1 [A] ❌ 5I4A_A:639 no longer at interface
A:639 [TYR] B:3 [U] A:861 [ALA] B:3 [A] ❌ 5I4A_A:639 no longer at interface

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Properties of this pair

Common ECOD label(s)
Common RFAM label(s)
Interface TM-score
Interface RMSD
Percentage identity
Protein TM-score
RNA TM-score
Protein coverage
RNA coverage
Percentage conservation
Apolar conservation
H-bond conservation
Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.77 3.58 0.05 0.77 0.16 0.45 0.5 0.56 0.62 0.16 0.80


Other pairs involving 5I4A_A_B or 6OON_A_B

Total number of entries: 28

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 6OON_A_B 0.99 0.95 1.78 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6MFN_A_C,E 6OON_A_B 0.88 0.89 1.67 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OON_A_B 0.95 0.95 2.24 0.83 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 6OON_A_B 0.96 0.98 0.65 0.45 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6D92_A_C 6OON_A_B 0.64 0.7 3.88 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OON_A_B 0.98 0.96 1.74 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6OON_A_B 6OZP_B_C,D 0.49 0.61 2.62 0.05 Ribonuclease H-like compare
6OON_A_B 6OZS_B_C,D 0.46 0.61 2.69 0.09 Ribonuclease H-like compare
6OON_A_B 6OZS_A_C,D 0.52 0.61 2.6 0.09 Ribonuclease H-like compare
6OON_A_B 6OZP_A_C,D 0.57 0.61 2.57 0.08 Ribonuclease H-like compare
5AWH_A_C 6OON_A_B 0.65 0.7 3.84 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OON_A_B 0.90 0.96 1.83 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6OON_A_B 0.90 0.96 1.89 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 6OON_A_B 0.97 0.98 0.92 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OON_A_B 0.88 0.96 1.87 0.42 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6OON_A_B 0.98 0.96 1.82 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6OON_A_B 0.90 0.95 1.87 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare