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All interfaces > All interologs > Interface groups > group140 > 6OON_A_B

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Licorice
Surface

RNA

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Licorice
Surface

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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

6OON_A
6OON_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:55 [LYS] B:15 [A] 4.26 34.01
A:56 [ARG] B:15 [A] 3.1 sugar:SC 2.5
A:57 [PRO] B:15 [A] 3.56 49.99
A:59 [ARG] B:15 [A] 4.27 36.91
A:60 [VAL] B:15 [A] 3.3 36.2
A:116 [GLN] B:15 [A] 4.93 41.95
A:118 [PHE] B:15 [A] 4.67 60.29
A:167 [VAL] B:9 [A] 4.73 70.02
A:209 [VAL] B:8 [A] 4.38 59.0
A:210 [SER] B:7 [A] 4.7 80.7
A:210 [SER] B:8 [A] 3.26 80.7
A:211 [ALA] B:7 [A] 3.38 60.78
A:211 [ALA] B:8 [A] 3.43 60.78
A:212 [THR] B:8 [A] 3.29 sugar:SC 74.78
A:256 [LYS] B:15 [A] 2.48 65.93
A:269 [TYR] B:20 [U] 3.43 sugar:SC 44.97
A:269 [TYR] B:21 [U] 4.51 44.97
A:270 [ARG] B:15 [A] 4.27 64.83
A:284 [PHE] B:21 [U] 3.1 base/AA stacks 84.78
A:285 [PRO] B:21 [U] 3.79 base:BB 5.53
A:286 [LEU] B:21 [U] 4.38 1.83
A:298 [VAL] B:21 [U] 4.28 95.14
A:301 [TYR] B:20 [U] 4.55 94.08
A:301 [TYR] B:21 [U] 2.82 94.08
A:302 [PHE] B:21 [U] 3.9 89.39
A:305 [LYS] B:20 [U] 4.23 52.47
A:305 [LYS] B:21 [U] 3.28 52.47
A:306 [TYR] B:21 [U] 3.32 85.78
A:327 [THR] B:21 [U] 2.84 sugar:BB 49.76
A:328 [TYR] B:21 [U] 2.7 sugar:BB 50.74
A:329 [LEU] B:21 [U] 3.94 59.97
A:346 [LEU] B:7 [A] 4.84 80.5
A:351 [THR] B:7 [A] 3.32 72.05
A:354 [MET] B:7 [A] 3.69 79.42
A:354 [MET] B:8 [A] 4.62 79.42
A:355 [ILE] B:6 [A] 3.52 85.56
A:355 [ILE] B:7 [A] 3.45 85.56
A:358 [THR] B:7 [A] 3.18 sugar:SC 77.02
A:359 [ALA] B:6 [A] 3.43 77.08
A:365 [ARG] B:7 [A] 4.0 96.06
A:514 [LEU] B:1 [A] 3.57 70.26
A:516 [GLY] B:1 [A] 2.97 36.34
A:517 [LYS] B:1 [A] 3.49 46.42
A:518 [THR] B:1 [A] 3.18 base:BB 54.78
A:521 [TYR] B:1 [A] 2.73 base/AA stacks 92.31
A:525 [LYS] B:1 [A] 2.58 99.0
A:536 [THR] B:1 [A] 3.6 94.97
A:537 [GLN] B:1 [A] 2.76 98.97
A:537 [GLN] B:2 [A] 4.61 98.97
A:538 [CYS] B:1 [A] 2.94 86.86
A:538 [CYS] B:2 [A] 3.85 86.86
A:539 [VAL] B:1 [A] 3.91 79.73
A:539 [VAL] B:2 [A] 3.64 79.73
A:540 [GLN] B:1 [A] 3.27 sugar:SC 41.87
A:540 [GLN] B:2 [A] 2.82 41.87
A:543 [ASN] B:2 [A] 2.83 77.89
A:550 [GLN] B:2 [A] 4.23 75.46
A:551 [THR] B:2 [A] 3.48 75.82
A:554 [ASN] B:2 [A] 2.98 base:SC 97.19
A:554 [ASN] B:3 [A] 3.91 97.19
A:555 [LEU] B:2 [A] 3.6 81.38
A:558 [LYS] B:1 [A] 2.81 98.72
A:558 [LYS] B:2 [A] 3.38 98.72
A:558 [LYS] B:3 [A] 2.95 98.72
A:562 [LYS] B:1 [A] 3.19 98.92
A:711 [LYS] B:6 [A] 2.84 98.94
A:712 [ARG] B:8 [A] 3.64 95.2
A:712 [ARG] B:9 [A] 3.1 95.2
A:714 [HIS] B:8 [A] 3.04 86.06
A:716 [ARG] B:6 [A] 4.56 97.03
A:716 [ARG] B:7 [A] 2.6 97.03
A:716 [ARG] B:8 [A] 4.6 97.03
A:755 [HIS] B:5 [A] 3.17 93.95
A:755 [HIS] B:6 [A] 2.91 93.95
A:756 [ALA] B:5 [A] 4.16 58.44
A:757 [GLY] B:5 [A] 4.14 83.97
A:758 [ILE] B:4 [A] 3.31 77.49
A:758 [ILE] B:5 [A] 3.16 sugar:BB 77.49
A:759 [GLN] B:5 [A] 3.61 79.81
A:759 [GLN] B:6 [A] 3.34 79.81
A:760 [GLY] B:6 [A] 4.52 98.64
A:761 [THR] B:6 [A] 3.32 98.61
A:761 [THR] B:7 [A] 3.95 98.61
A:762 [SER] B:5 [A] 4.85 92.03
A:762 [SER] B:6 [A] 3.38 92.03
A:763 [ARG] B:6 [A] 2.71 89.34
A:763 [ARG] B:7 [A] 3.0 89.34
A:763 [ARG] B:8 [A] 2.81 89.34
A:792 [TYR] B:3 [A] 4.55 79.22
A:792 [TYR] B:4 [A] 2.59 79.22
A:794 [ARG] B:3 [A] 3.51 94.81
A:794 [ARG] B:4 [A] 2.98 94.81
A:795 [CYS] B:3 [A] 3.26 82.03
A:795 [CYS] B:4 [A] 3.7 82.03
A:797 [ARG] B:3 [A] 4.86 89.11
A:797 [ARG] B:4 [A] 3.12 sugar:SC 89.11
A:799 [VAL] B:4 [A] 3.82 94.0
A:799 [VAL] B:5 [A] 3.7 94.0
A:800 [SER] B:4 [A] 4.69 97.47
A:800 [SER] B:5 [A] 2.64 97.47
A:800 [SER] B:6 [A] 4.57 97.47
A:801 [ILE] B:5 [A] 4.81 71.01
A:806 [TYR] B:4 [A] 3.57 75.67
A:806 [TYR] B:5 [A] 2.54 75.67
A:814 [ARG] B:1 [A] 3.47 95.97
A:817 [TYR] B:1 [A] 3.75 0.0
A:861 [ALA] B:1 [A] 4.09 75.56
A:861 [ALA] B:3 [A] 4.55 75.56

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group140 6OON_A_B A: Protein argonaute-4, Homo sapiens (genetically engineered) B: Homo sapiens (genetically engineered) Q9HCK5 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs ✘

Interologs

Total number of interologs for this interface: 18

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 6OON_A_B 0.99 0.95 1.78 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6MFN_A_C,E 6OON_A_B 0.88 0.89 1.67 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4KXT_A_B 6OON_A_B 0.95 0.95 2.24 0.83 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 6OON_A_B 0.96 0.98 0.65 0.45 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6D92_A_C 6OON_A_B 0.64 0.7 3.88 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OON_A_B 0.98 0.96 1.74 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6OON_A_B 0.65 0.7 3.84 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OON_A_B 0.90 0.96 1.83 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6OON_A_B 0.90 0.96 1.89 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 6OON_A_B 0.97 0.98 0.92 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6OON_A_B 0.88 0.96 1.87 0.42 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6OON_A_B 0.98 0.96 1.82 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6OON_A_B 0.90 0.95 1.87 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6OON_A_B 6OZP_A_C,D 0.57 0.61 2.57 0.08 Ribonuclease H-like compare
6OON_A_B 6OZP_B_C,D 0.49 0.61 2.62 0.05 Ribonuclease H-like compare
6OON_A_B 6OZS_A_C,D 0.52 0.61 2.6 0.09 Ribonuclease H-like compare
6OON_A_B 6OZS_B_C,D 0.46 0.61 2.69 0.09 Ribonuclease H-like compare