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All interfaces > All interologs > Interface groups > group141 > 5HO4_A_B

Interface analysis

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Protein

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Licorice
Surface

RNA

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Licorice
Surface

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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

5HO4_A
5HO4_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:19 [GLN] B:3 [G] 2.85 base:SC 53.92
A:22 [LYS] B:3 [G] 2.74 base:SC 82.53
A:22 [LYS] B:4 [G] 2.89 base:SC 82.53
A:22 [LYS] B:5 [A] 4.1 82.53
A:24 [PHE] B:1 [A] 3.94 77.5
A:24 [PHE] B:2 [A] 3.41 base/AA stacks 77.5
A:26 [GLY] B:1 [A] 3.65 70.07
A:27 [GLY] B:1 [A] 3.42 sugar:BB 83.6
A:49 [ASP] B:4 [G] 2.64 base:SC, base:SC 55.45
A:49 [ASP] B:5 [A] 4.05 55.45
A:50 [CYS] B:4 [G] 4.41 70.64
A:51 [VAL] B:4 [G] 3.68 10.23
A:53 [MET] B:3 [G] 3.39 61.22
A:53 [MET] B:4 [G] 3.39 61.22
A:62 [ARG] B:1 [A] 3.18 83.83
A:62 [ARG] B:2 [A] 4.67 83.83
A:62 [ARG] B:3 [G] 3.04 83.83
A:62 [ARG] B:4 [G] 3.38 83.83
A:63 [GLY] B:1 [A] 3.55 89.33
A:64 [PHE] B:1 [A] 3.77 59.14
A:64 [PHE] B:2 [A] 3.61 59.14
A:64 [PHE] B:3 [G] 3.81 59.14
A:66 [PHE] B:2 [A] 3.69 86.38
A:66 [PHE] B:3 [G] 3.24 base/AA stacks 86.38
A:90 [VAL] B:1 [A] 4.81 0.43
A:92 [GLU] B:1 [A] 2.46 base:SC 48.7
A:94 [LYS] B:2 [A] 4.0 56.7
A:95 [ARG] B:2 [A] 3.58 base:BB 32.95
A:96 [ALA] B:2 [A] 3.53 60.27
A:96 [ALA] B:3 [G] 3.74 60.27
A:97 [VAL] B:2 [A] 2.86 base:BB 5.91
A:97 [VAL] B:3 [G] 2.76 base:BB 5.91
A:98 [ALA] B:3 [G] 4.02 58.88
A:99 [ARG] B:3 [G] 3.36 59.32
A:99 [ARG] B:4 [G] 4.67 59.32
A:99 [ARG] B:7 [U] 2.81 base:SC 59.32
A:102 [SER] B:2 [A] 4.49 47.41
A:102 [SER] B:3 [G] 3.13 base:SC 47.41
A:108 [HIS] B:2 [A] 3.13 base/AA stacks 11.82
A:108 [HIS] B:3 [G] 4.9 11.82

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group141 5HO4_A_B A: Heterogeneous nuclear ribonucleoproteins a2/b1, Homo sapiens (synthetic) B: Synthetic construct (synthetic) P22626 RNA-binding domain, RBD ✘

Interologs

Total number of interologs for this interface: 4

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
5HO4_A_B 5WWE_A_B 0.93 0.93 0.72 0.6 RNA-binding domain, RBD compare
5HO4_A_B 5WWF_A_B 0.87 0.94 0.85 0.4 RNA-binding domain, RBD compare
5HO4_A_B 6DCL_A_C 0.98 0.92 0.75 0.4 RNA-binding domain, RBD compare
1URN_A_P 5HO4_A_B 0.68 0.59 2.13 0.0 RNA-binding domain, RBD compare