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All interfaces > All interologs > Interface groups > group141 > 5WWE_A_B

Interface analysis

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Protein

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Licorice
Surface

RNA

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Licorice
Surface

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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

5WWE_A
5WWE_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:18 [GLU] B:2 [G] 4.92 52.18
A:18 [GLU] B:4 [G] 3.19 base:SC 52.18
A:18 [GLU] B:5 [A] 3.52 52.18
A:19 [GLN] B:2 [G] 2.8 base:SC 54.36
A:22 [LYS] B:2 [G] 2.52 base:SC 81.53
A:22 [LYS] B:3 [G] 2.7 base:SC 81.53
A:22 [LYS] B:4 [G] 3.61 81.53
A:24 [PHE] B:1 [A] 3.41 base/AA stacks 83.21
A:49 [ASP] B:3 [G] 2.66 base:SC, base:SC 52.82
A:49 [ASP] B:4 [G] 3.14 52.82
A:50 [CYS] B:3 [G] 3.79 73.17
A:51 [VAL] B:3 [G] 3.42 5.91
A:53 [MET] B:2 [G] 3.52 57.88
A:53 [MET] B:3 [G] 3.38 57.88
A:62 [ARG] B:1 [A] 4.65 85.77
A:62 [ARG] B:2 [G] 3.11 85.77
A:62 [ARG] B:3 [G] 3.47 85.77
A:64 [PHE] B:1 [A] 3.64 73.78
A:64 [PHE] B:2 [G] 4.22 73.78
A:66 [PHE] B:1 [A] 3.73 96.08
A:66 [PHE] B:2 [G] 3.2 base/AA stacks 96.08
A:66 [PHE] B:3 [G] 4.52 96.08
A:94 [LYS] B:1 [A] 3.97 60.63
A:95 [ARG] B:1 [A] 3.38 base:BB 46.01
A:96 [ALA] B:1 [A] 3.36 69.68
A:96 [ALA] B:2 [G] 3.7 69.68
A:97 [VAL] B:1 [A] 2.73 base:BB 3.89
A:97 [VAL] B:2 [G] 2.71 base:BB, base:BB 3.89
A:98 [ALA] B:2 [G] 3.99 52.03
A:99 [ARG] B:2 [G] 2.74 sugar:SC base/AA stacks 61.49
A:99 [ARG] B:3 [G] 4.26 61.49
A:99 [ARG] B:4 [G] 2.54 base:SC 61.49
A:99 [ARG] B:5 [A] 3.47 61.49
A:102 [SER] B:1 [A] 3.57 sugar:SC 61.56
A:102 [SER] B:2 [G] 3.23 base:SC 61.56
A:108 [HIS] B:1 [A] 3.21 base/AA stacks 8.9

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group141 5WWE_A_B A: Heterogeneous nuclear ribonucleoproteins a2/b1, Homo sapiens (genetically engineered) B: Synthetic construct (synthetic) P22626 RNA-binding domain, RBD ✘

Interologs

Total number of interologs for this interface: 3

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
1A9N_B_Q 5WWE_A_B 0.72 0.6 2.34 0.2 RNA-binding domain, RBD compare
5HO4_A_B 5WWE_A_B 0.93 0.93 0.72 0.6 RNA-binding domain, RBD compare
5WWE_A_B 5WWF_A_B 0.98 0.88 1.37 0.8 RNA-binding domain, RBD compare