Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
4RWN_A
|
4RWN_B,C
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:12 [ASP] | C:35 [A] | 3.34 | B:4 [U] | 81.39 | ||
A:12 [ASP] | C:36 [G] | 3.57 | B:3 [C] | 81.39 | ||
A:13 [LYS] | C:35 [A] | 4.66 | B:4 [U] | 20.55 | ||
A:13 [LYS] | C:36 [G] | 3.73 | B:3 [C] | 20.55 | ||
A:13 [LYS] | C:37 [C] | 2.98 | B:2 [G] | 20.55 | ||
A:16 [GLU] | B:5 [U] | 4.67 | C:34 [A] | 47.64 | ||
A:16 [GLU] | C:35 [A] | 2.59 | B:4 [U] | sugar:SC | 47.64 | |
A:16 [GLU] | C:36 [G] | 3.43 | B:3 [C] | 47.64 | ||
A:17 [ASP] | C:36 [G] | 4.94 | B:3 [C] | 33.01 | ||
A:20 [LEU] | B:6 [U] | 3.81 | C:33 [A] | 75.69 | ||
A:20 [LEU] | C:35 [A] | 4.96 | B:4 [U] | 75.69 | ||
A:21 [PRO] | B:5 [U] | 4.71 | C:34 [A] | 81.11 | ||
A:21 [PRO] | B:6 [U] | 3.15 | C:33 [A] | 81.11 | ||
A:21 [PRO] | B:7 [U] | 3.78 | C:32 [A] | 81.11 | ||
A:22 [ASN] | B:6 [U] | 4.22 | C:33 [A] | 57.64 | ||
A:23 [THR] | B:5 [U] | 3.44 | C:34 [A] | 45.82 | ||
A:23 [THR] | B:6 [U] | 2.81 | C:33 [A] | 45.82 | ||
A:26 [ARG] | B:6 [U] | 2.74 | C:33 [A] | 24.07 | ||
A:26 [ARG] | B:7 [U] | 3.68 | C:32 [A] | 24.07 | ||
A:27 [THR] | C:26 [A] | 4.71 | B:13 [U] | 22.09 | ||
A:30 [LYS] | C:25 [A] | 3.49 | B:14 [U] | 47.87 | ||
A:30 [LYS] | C:26 [A] | 3.09 | B:13 [U] | 47.87 | ||
A:31 [GLU] | C:25 [A] | 4.98 | B:14 [U] | 25.25 | ||
A:33 [ILE] | C:24 [U] | 3.6 | B:15 [A] | 78.58 | ||
A:33 [ILE] | C:25 [A] | 4.33 | B:14 [U] | 78.58 | ||
A:34 [ASP] | C:24 [U] | 3.95 | B:15 [A] | 58.59 | ||
A:34 [ASP] | C:25 [A] | 3.63 | B:14 [U] | 58.59 | ||
A:37 [CYS] | C:24 [U] | 3.61 | B:15 [A] | 50.63 | ||
A:41 [LYS] | B:16 [U] | 3.16 | C:23 [A] | base:SC | 67.43 | |
A:41 [LYS] | B:17 [G] | 3.49 | C:22 [C] | 67.43 | ||
A:41 [LYS] | C:23 [A] | 4.43 | B:16 [U] | 67.43 | ||
A:41 [LYS] | C:24 [U] | 3.52 | B:15 [A] | 67.43 | ||
A:42 [GLU] | B:16 [U] | 2.82 | C:23 [A] | sugar:SC | 50.22 | |
A:42 [GLU] | B:17 [G] | 4.83 | C:22 [C] | 50.22 | ||
A:53 [ARG] | B:18 [A] | 3.46 | C:21 [U] | 57.42 | ||
A:53 [ARG] | B:19 [A] | 3.38 | C:20 [U] | 57.42 | ||
A:54 [VAL] | B:17 [G] | 2.67 | C:22 [C] | sugar:BB | 88.96 | |
A:54 [VAL] | B:18 [A] | 3.21 | C:21 [U] | 88.96 | ||
A:55 [SER] | B:17 [G] | 2.96 | C:22 [C] | base:BB | 45.24 | |
A:55 [SER] | B:18 [A] | 3.43 | C:21 [U] | 45.24 | ||
A:55 [SER] | C:22 [C] | 4.24 | B:17 [G] | 45.24 | ||
A:55 [SER] | C:23 [A] | 4.91 | B:16 [U] | 45.24 | ||
A:56 [LYS] | B:17 [G] | 4.79 | C:22 [C] | 57.23 | ||
A:56 [LYS] | C:22 [C] | 4.02 | B:17 [G] | 57.23 | ||
A:56 [LYS] | C:23 [A] | 3.57 | B:16 [U] | 57.23 | ||
A:57 [VAL] | C:23 [A] | 2.65 | B:16 [U] | sugar:BB | 83.38 | |
A:57 [VAL] | C:24 [U] | 3.07 | B:15 [A] | 83.38 | ||
A:58 [VAL] | C:23 [A] | 3.8 | B:16 [U] | 77.59 | ||
A:58 [VAL] | C:24 [U] | 3.58 | B:15 [A] | 77.59 | ||
A:59 [LYS] | C:23 [A] | 4.38 | B:16 [U] | 87.47 | ||
A:59 [LYS] | C:24 [U] | 2.76 | B:15 [A] | 87.47 | ||
A:59 [LYS] | C:25 [A] | 2.73 | B:14 [U] | 87.47 | ||
A:63 [SER] | B:8 [G] | 4.68 | C:31 [C] | 68.91 | ||
A:64 [GLY] | B:8 [G] | 4.53 | C:31 [C] | 82.92 | ||
A:65 [LYS] | B:7 [U] | 4.37 | C:32 [A] | 93.04 | ||
A:65 [LYS] | B:8 [G] | 4.12 | C:31 [C] | 93.04 | ||
A:66 [GLY] | B:7 [U] | 3.66 | C:32 [A] | 86.39 | ||
A:66 [GLY] | B:8 [G] | 3.24 | C:31 [C] | 86.39 | ||
A:68 [THR] | B:7 [U] | 4.89 | C:32 [A] | 77.09 | ||
A:82 [THR] | B:18 [A] | 3.94 | C:21 [U] | 80.98 | ||
A:82 [THR] | B:19 [A] | 4.24 | C:20 [U] | 80.98 | ||
A:157 [GLN] | B:18 [A] | 3.61 | C:21 [U] | 37.96 | ||
A:157 [GLN] | B:19 [A] | 3.67 | C:20 [U] | 37.96 | ||
A:157 [GLN] | C:21 [U] | 2.71 | B:18 [A] | base:SC, sugar:SC | 37.96 | |
A:157 [GLN] | C:22 [C] | 3.54 | B:17 [G] | base/AA stacks | 37.96 | |
A:158 [TRP] | C:22 [C] | 3.98 | B:17 [G] | 10.63 | ||
A:160 [PRO] | C:22 [C] | 4.99 | B:17 [G] | 16.98 | ||
A:191 [GLU] | C:22 [C] | 4.55 | B:17 [G] | 66.95 | ||
A:191 [GLU] | C:23 [A] | 4.05 | B:16 [U] | 66.95 | ||
A:194 [ARG] | C:23 [A] | 4.18 | B:16 [U] | 70.95 | ||
A:194 [ARG] | C:24 [U] | 2.78 | B:15 [A] | 70.95 | ||
A:198 [ARG] | B:7 [U] | 4.49 | C:32 [A] | 55.64 | ||
A:198 [ARG] | B:8 [G] | 3.19 | C:31 [C] | 55.64 | ||
A:198 [ARG] | B:9 [A] | 3.74 | C:30 [U] | 55.64 | ||
A:198 [ARG] | C:24 [U] | 4.74 | B:15 [A] | 55.64 | ||
A:199 [ASN] | B:8 [G] | 3.75 | C:31 [C] | 35.46 | ||
A:199 [ASN] | B:9 [A] | 4.57 | C:30 [U] | 35.46 | ||
A:200 [ARG] | B:7 [U] | 4.49 | C:32 [A] | 54.68 | ||
A:201 [PRO] | C:33 [A] | 4.78 | B:6 [U] | 86.34 | ||
A:202 [THR] | B:6 [U] | 3.97 | C:33 [A] | 47.01 | ||
A:202 [THR] | B:7 [U] | 3.27 | C:32 [A] | base:SC | 47.01 | |
A:202 [THR] | C:33 [A] | 2.75 | B:6 [U] | base:SC | 47.01 | |
A:202 [THR] | C:34 [A] | 3.82 | B:5 [U] | 47.01 | ||
A:203 [LYS] | C:34 [A] | 3.59 | B:5 [U] | 69.37 | ||
A:203 [LYS] | C:35 [A] | 2.99 | B:4 [U] | 69.37 | ||
A:205 [LYS] | B:7 [U] | 2.94 | C:32 [A] | sugar:SC | 87.26 | |
A:205 [LYS] | B:8 [G] | 3.16 | C:31 [C] | 87.26 | ||
A:206 [SER] | C:34 [A] | 4.97 | B:5 [U] | 64.45 | ||
A:209 [ARG] | B:6 [U] | 3.97 | C:33 [A] | 90.83 | ||
A:209 [ARG] | B:7 [U] | 3.34 | C:32 [A] | 90.83 | ||
A:247 [THR] | C:33 [A] | 3.23 | B:6 [U] | 20.55 | ||
A:247 [THR] | C:34 [A] | 2.94 | B:5 [U] | 20.55 | ||
A:248 [ASP] | C:34 [A] | 3.6 | B:5 [U] | 46.78 | ||
A:248 [ASP] | C:35 [A] | 3.53 | B:4 [U] | 46.78 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group41 | 4RWN_A_B,C | A: 2'-5'-oligoadenylate synthase 1, Sus scrofa (genetically engineered) B: Synthetic construct (synthetic) C: Synthetic construct (synthetic) | Q29599 | PAP/OAS1 substrate-binding domain & Nucleotidyltransferase | ✘ |
Interologs
Total number of interologs for this interface: 2
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
4RWN_A_B,C | 4RWO_A_B,C | 0.98 | 1.0 | 0.24 | 0.95 | PAP/OAS1 substrate-binding domain & Nucleotidyltransferase | compare | |
4RWN_A_B,C | 4S3N_A_B,C | 0.80 | 0.9 | 0.98 | 0.42 | PAP/OAS1 substrate-binding domain & Nucleotidyltransferase | compare |