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All interfaces > All interologs > Interface groups > group41 > 4RWO_A_B,C

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Licorice
Surface

RNA

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Licorice
Surface

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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

4RWO_A
4RWO_B,C
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:12 [ASP] C:35 [A] 3.41 B:4 [U] 85.24
A:12 [ASP] C:36 [G] 3.44 B:3 [C] 85.24
A:13 [LYS] C:35 [A] 4.77 B:4 [U] 40.06
A:13 [LYS] C:36 [G] 3.66 B:3 [C] 40.06
A:13 [LYS] C:37 [C] 3.17 B:2 [G] 40.06
A:16 [GLU] B:5 [U] 4.53 C:34 [A] 41.05
A:16 [GLU] C:35 [A] 2.58 B:4 [U] sugar:SC 41.05
A:16 [GLU] C:36 [G] 3.42 B:3 [C] 41.05
A:20 [LEU] B:6 [U] 3.67 C:33 [A] 74.54
A:21 [PRO] B:5 [U] 4.85 C:34 [A] 85.76
A:21 [PRO] B:6 [U] 3.11 C:33 [A] 85.76
A:21 [PRO] B:7 [U] 3.91 C:32 [A] 85.76
A:22 [ASN] B:6 [U] 4.13 C:33 [A] 57.12
A:23 [THR] B:5 [U] 3.57 C:34 [A] 45.36
A:23 [THR] B:6 [U] 2.91 C:33 [A] 45.36
A:26 [ARG] B:6 [U] 2.91 C:33 [A] 37.81
A:26 [ARG] B:7 [U] 3.53 C:32 [A] 37.81
A:27 [THR] C:26 [A] 4.97 B:13 [U] 17.04
A:30 [LYS] C:25 [A] 3.33 B:14 [U] 46.82
A:30 [LYS] C:26 [A] 2.94 B:13 [U] 46.82
A:33 [ILE] C:24 [U] 3.76 B:15 [A] 75.87
A:33 [ILE] C:25 [A] 4.24 B:14 [U] 75.87
A:34 [ASP] C:24 [U] 4.22 B:15 [A] 48.63
A:34 [ASP] C:25 [A] 3.5 B:14 [U] 48.63
A:37 [CYS] C:24 [U] 3.42 B:15 [A] 62.86
A:41 [LYS] B:16 [U] 2.83 C:23 [A] base:SC 64.89
A:41 [LYS] B:17 [G] 3.24 C:22 [C] 64.89
A:41 [LYS] C:23 [A] 4.24 B:16 [U] 64.89
A:41 [LYS] C:24 [U] 3.35 B:15 [A] 64.89
A:42 [GLU] B:16 [U] 2.76 C:23 [A] sugar:SC 56.88
A:42 [GLU] B:17 [G] 4.83 C:22 [C] 56.88
A:46 [GLN] B:17 [G] 4.7 C:22 [C] 37.65
A:53 [ARG] B:18 [A] 3.63 C:21 [U] 57.89
A:53 [ARG] B:19 [A] 3.46 C:20 [U] 57.89
A:54 [VAL] B:17 [G] 2.78 C:22 [C] sugar:BB 91.16
A:54 [VAL] B:18 [A] 3.25 C:21 [U] 91.16
A:55 [SER] B:17 [G] 2.99 C:22 [C] base:BB 51.47
A:55 [SER] B:18 [A] 3.23 C:21 [U] 51.47
A:55 [SER] C:22 [C] 4.36 B:17 [G] 51.47
A:56 [LYS] B:17 [G] 4.7 C:22 [C] 62.83
A:56 [LYS] C:22 [C] 3.9 B:17 [G] 62.83
A:56 [LYS] C:23 [A] 3.62 B:16 [U] 62.83
A:57 [VAL] C:23 [A] 2.45 B:16 [U] sugar:BB 78.1
A:57 [VAL] C:24 [U] 3.36 B:15 [A] 78.1
A:58 [VAL] C:23 [A] 3.91 B:16 [U] 72.87
A:58 [VAL] C:24 [U] 4.0 B:15 [A] 72.87
A:59 [LYS] C:23 [A] 4.38 B:16 [U] 88.4
A:59 [LYS] C:24 [U] 3.08 B:15 [A] 88.4
A:59 [LYS] C:25 [A] 2.78 B:14 [U] 88.4
A:63 [SER] B:8 [G] 4.92 C:31 [C] 65.45
A:64 [GLY] B:8 [G] 4.25 C:31 [C] 76.64
A:65 [LYS] B:7 [U] 4.46 C:32 [A] 86.3
A:65 [LYS] B:8 [G] 3.89 C:31 [C] 86.3
A:66 [GLY] B:7 [U] 3.62 C:32 [A] 82.99
A:66 [GLY] B:8 [G] 3.45 C:31 [C] 82.99
A:82 [THR] B:19 [A] 4.42 C:20 [U] 76.46
A:157 [GLN] B:18 [A] 3.89 C:21 [U] 42.78
A:157 [GLN] B:19 [A] 3.75 C:20 [U] 42.78
A:157 [GLN] C:21 [U] 2.7 B:18 [A] base:SC, sugar:SC 42.78
A:157 [GLN] C:22 [C] 3.39 B:17 [G] 42.78
A:158 [TRP] C:22 [C] 3.83 B:17 [G] 26.48
A:158 [TRP] C:23 [A] 4.5 B:16 [U] 26.48
A:159 [THR] C:22 [C] 4.21 B:17 [G] 24.75
A:160 [PRO] C:23 [A] 4.54 B:16 [U] 9.03
A:191 [GLU] C:22 [C] 4.58 B:17 [G] 70.87
A:191 [GLU] C:23 [A] 3.93 B:16 [U] 70.87
A:194 [ARG] C:23 [A] 4.33 B:16 [U] 66.59
A:194 [ARG] C:24 [U] 4.53 B:15 [A] 66.59
A:198 [ARG] B:7 [U] 4.69 C:32 [A] 52.5
A:198 [ARG] B:8 [G] 3.2 C:31 [C] 52.5
A:198 [ARG] B:9 [A] 3.67 C:30 [U] 52.5
A:199 [ASN] B:8 [G] 3.06 C:31 [C] 30.88
A:199 [ASN] B:9 [A] 3.03 C:30 [U] 30.88
A:200 [ARG] B:7 [U] 4.93 C:32 [A] 55.53
A:201 [PRO] C:33 [A] 4.9 B:6 [U] 86.04
A:202 [THR] B:6 [U] 4.07 C:33 [A] 48.16
A:202 [THR] B:7 [U] 3.43 C:32 [A] 48.16
A:202 [THR] C:33 [A] 2.82 B:6 [U] base:SC 48.16
A:202 [THR] C:34 [A] 4.02 B:5 [U] 48.16
A:203 [LYS] C:34 [A] 3.72 B:5 [U] 78.03
A:203 [LYS] C:35 [A] 2.85 B:4 [U] 78.03
A:205 [LYS] B:7 [U] 2.7 C:32 [A] sugar:SC 86.51
A:205 [LYS] B:8 [G] 2.85 C:31 [C] 86.51
A:209 [ARG] B:6 [U] 4.19 C:33 [A] 90.39
A:209 [ARG] B:7 [U] 3.89 C:32 [A] 90.39
A:247 [THR] C:33 [A] 3.45 B:6 [U] 24.31
A:247 [THR] C:34 [A] 2.95 B:5 [U] 24.31
A:248 [ASP] C:34 [A] 3.79 B:5 [U] 50.27
A:248 [ASP] C:35 [A] 3.48 B:4 [U] 50.27

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group41 4RWO_A_B,C A: 2'-5'-oligoadenylate synthase 1, Sus scrofa (genetically engineered) B: Synthetic construct (synthetic) C: Synthetic construct (synthetic) Q29599 PAP/OAS1 substrate-binding domain & Nucleotidyltransferase ✘

Interologs

Total number of interologs for this interface: 2

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4RWO_A_B,C 4S3N_A_B,C 0.81 0.89 1.07 0.42 PAP/OAS1 substrate-binding domain & Nucleotidyltransferase compare
4RWN_A_B,C 4RWO_A_B,C 0.98 1.0 0.24 0.95 PAP/OAS1 substrate-binding domain & Nucleotidyltransferase compare