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All interfaces > All interologs > Interface groups > group47 > 5XH6_A_B

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Licorice
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Licorice
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Chain
Chain (with hetatm)
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Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

5XH6_A
5XH6_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:14 [SER] B:0 [G] 3.39 C:0 [DC] 83.35
A:15 [LYS] B:0 [G] 2.91 C:0 [DC] 97.56
A:16 [THR] B:0 [G] 2.79 C:0 [DC] base:SC, base:SC, sugar:BB 99.0
A:16 [THR] B:1 [G] 3.22 C:-1 [DC] 99.0
A:18 [ARG] B:-16 [U] 2.93 B:-1 [U] base:SC, base:SC 96.57
A:18 [ARG] B:-15 [U] 3.63 B:-2 [A] 96.57
A:18 [ARG] B:-1 [U] 4.01 B:-16 [U] 96.57
A:18 [ARG] B:1 [G] 3.58 C:-1 [DC] 96.57
A:19 [PHE] B:-16 [U] 3.64 B:-1 [U] 85.79
A:20 [GLU] B:-16 [U] 3.65 B:-1 [U] 86.47
A:47 [TYR] B:3 [A] 3.43 C:-3 [DT] 88.45
A:47 [TYR] B:4 [A] 2.63 C:-4 [DT] 88.45
A:51 [LYS] B:4 [A] 3.59 C:-4 [DT] 98.36
A:51 [LYS] B:5 [U] 3.08 C:-5 [DA] 98.36
A:55 [ASP] B:5 [U] 4.04 C:-5 [DA] 96.65
A:171 [GLY] B:3 [A] 4.46 C:-3 [DT] 79.53
A:172 [PHE] B:3 [A] 4.33 C:-3 [DT] 89.8
A:172 [PHE] B:4 [A] 4.49 C:-4 [DT] 89.8
A:175 [ASN] B:3 [A] 2.45 C:-3 [DT] base:SC, sugar:SC 91.84
A:175 [ASN] B:4 [A] 2.92 C:-4 [DT] 91.84
A:176 [ARG] B:4 [A] 2.99 C:-4 [DT] sugar:SC 98.83
A:176 [ARG] B:5 [U] 3.31 C:-5 [DA] 98.83
A:187 [THR] B:4 [A] 4.64 C:-4 [DT] 92.01
A:187 [THR] B:5 [U] 4.4 C:-5 [DA] 92.01
A:192 [ARG] B:6 [U] 3.02 C:-6 [DA] sugar:SC 98.97
A:192 [ARG] B:7 [A] 3.65 C:-7 [DT] 98.97
A:268 [GLU] B:14 [C] 4.61 C:-14 [DG] 49.07
A:269 [ALA] B:13 [G] 4.42 C:-13 [DC] 32.26
A:269 [ALA] B:14 [C] 3.62 C:-14 [DG] 32.26
A:270 [GLY] B:14 [C] 2.94 C:-14 [DG] sugar:BB 62.37
A:270 [GLY] B:15 [U] 3.69 C:-15 [DA] 62.37
A:271 [THR] B:14 [C] 4.46 C:-14 [DG] 47.45
A:271 [THR] B:15 [U] 3.24 C:-15 [DA] 47.45
A:272 [GLU] B:15 [U] 3.69 C:-15 [DA] 41.2
A:272 [GLU] B:16 [U] 4.1 C:-16 [DA] 41.2
A:273 [LYS] B:15 [U] 3.04 C:-15 [DA] sugar:BB 88.61
A:275 [LYS] B:16 [U] 4.05 C:-16 [DA] 76.52
A:279 [GLU] B:15 [U] 4.56 C:-15 [DA] 80.68
A:283 [LEU] B:16 [U] 3.42 C:-16 [DA] 78.92
A:283 [LEU] B:17 [G] 3.7 C:-17 [DC] 78.92
A:286 [GLN] B:17 [G] 2.74 C:-17 [DC] base:SC, base:SC, sugar:SC 97.04
A:286 [GLN] B:18 [G] 3.2 C:-18 [DC] 97.04
A:288 [ASN] B:18 [G] 3.91 C:-18 [DC] 54.31
A:288 [ASN] B:19 [C] 4.72 C:-19 [DG] 54.31
A:306 [PHE] B:6 [U] 4.76 C:-6 [DA] 69.93
A:306 [PHE] B:7 [A] 3.3 C:-7 [DT] 69.93
A:306 [PHE] B:8 [G] 3.87 C:-8 [DC] 69.93
A:307 [LYS] B:6 [U] 2.7 C:-6 [DA] 98.72
A:307 [LYS] B:7 [A] 2.93 C:-7 [DT] 98.72
A:308 [GLN] B:6 [U] 3.79 C:-6 [DA] 97.09
A:309 [ILE] B:5 [U] 3.75 C:-5 [DA] 98.75
A:309 [ILE] B:6 [U] 3.73 C:-6 [DA] 98.75
A:310 [LEU] B:5 [U] 3.5 C:-5 [DA] 93.17
A:310 [LEU] B:6 [U] 2.81 C:-6 [DA] 93.17
A:311 [SER] B:6 [U] 4.14 C:-6 [DA] 95.52
A:313 [ARG] B:7 [A] 3.29 C:-7 [DT] 72.37
A:369 [LYS] B:16 [U] 2.91 C:-16 [DA] 59.04
A:369 [LYS] B:17 [G] 3.66 C:-17 [DC] 59.04
A:372 [GLU] B:19 [C] 3.59 C:-19 [DG] 78.2
A:382 [TRP] B:19 [C] 3.32 C:-19 [DG] base/AA stacks 77.08
A:382 [TRP] B:20 [A] 4.19 77.08
A:386 [ARG] B:20 [A] 3.27 8.43
A:414 [LYS] B:18 [G] 2.76 C:-18 [DC] 57.38
A:414 [LYS] B:19 [C] 3.12 C:-19 [DG] 57.38
A:475 [LEU] B:13 [G] 4.5 C:-13 [DC] 63.93
A:475 [LEU] B:14 [C] 4.71 C:-14 [DG] 63.93
A:478 [TYR] B:14 [C] 4.94 C:-14 [DG] 56.12
A:479 [HIS] B:13 [G] 4.53 C:-13 [DC] 72.13
A:479 [HIS] B:14 [C] 2.62 C:-14 [DG] 72.13
A:511 [LEU] B:13 [G] 3.6 C:-13 [DC] 69.56
A:511 [LEU] B:14 [C] 3.74 C:-14 [DG] 69.56
A:514 [TYR] B:12 [C] 3.84 C:-12 [DG] 94.63
A:514 [TYR] B:13 [G] 3.97 C:-13 [DC] 94.63
A:515 [ASN] B:13 [G] 2.87 C:-13 [DC] sugar:SC 93.39
A:518 [ARG] B:11 [G] 4.3 C:-11 [DC] 98.81
A:518 [ARG] B:12 [C] 3.05 C:-12 [DG] sugar:SC 98.81
A:518 [ARG] B:13 [G] 3.2 C:-13 [DC] sugar:SC 98.81
A:530 [LYS] B:1 [G] 4.84 C:-1 [DC] 98.59
A:530 [LYS] B:2 [A] 2.53 C:-2 [DT] 98.59
A:746 [TYR] B:-16 [U] 3.91 B:-1 [U] 85.27
A:747 [ASN] B:-16 [U] 3.3 B:-1 [U] 96.13
A:748 [LYS] B:-17 [U] 2.99 96.57
A:748 [LYS] B:-16 [U] 2.76 B:-1 [U] 96.57
A:748 [LYS] B:-15 [U] 4.38 B:-2 [A] 96.57
A:748 [LYS] B:-14 [C] 4.6 B:-3 [G] 96.57
A:748 [LYS] B:-5 [U] 4.18 B:-12 [A] 96.57
A:748 [LYS] B:-4 [A] 4.57 B:-13 [U] 96.57
A:751 [ALA] B:-6 [G] 3.33 B:-11 [C] 93.47
A:752 [LYS] B:-6 [G] 3.85 B:-11 [C] 31.39
A:753 [GLY] B:-8 [U] 4.83 34.02
A:753 [GLY] B:-7 [U] 4.61 34.02
A:753 [GLY] B:-6 [G] 2.95 B:-11 [C] 34.02
A:753 [GLY] B:-5 [U] 4.4 B:-12 [A] 34.02
A:754 [HIS] B:-6 [G] 3.66 B:-11 [C] 88.31
A:754 [HIS] B:-5 [U] 3.54 B:-12 [A] 88.31
A:755 [HIS] B:-8 [U] 2.84 base:SC 75.5
A:755 [HIS] B:-6 [G] 3.61 B:-11 [C] 75.5
A:755 [HIS] B:-5 [U] 2.87 B:-12 [A] 75.5
A:756 [GLY] B:-5 [U] 2.87 B:-12 [A] 91.82
A:756 [GLY] B:-4 [A] 3.44 B:-13 [U] 91.82
A:757 [LYS] B:-5 [U] 4.72 B:-12 [A] 63.47
A:757 [LYS] B:-4 [A] 2.92 B:-13 [U] 63.47
A:757 [LYS] B:-3 [G] 3.4 B:-14 [C] 63.47
A:758 [PRO] B:-3 [G] 4.6 B:-14 [C] 65.29
A:759 [ASN] B:-16 [U] 3.42 B:-1 [U] base:SC 98.78
A:759 [ASN] B:-15 [U] 3.93 B:-2 [A] 98.78
A:759 [ASN] B:-3 [G] 4.3 B:-14 [C] 98.78
A:759 [ASN] B:-2 [A] 3.15 B:-15 [U] 98.78
A:759 [ASN] B:-1 [U] 3.23 B:-16 [U] 98.78
A:760 [LEU] B:-2 [A] 3.69 B:-15 [U] 89.0
A:760 [LEU] B:-1 [U] 3.24 B:-16 [U] base:BB 89.0
A:761 [HIS] B:-16 [U] 4.24 B:-1 [U] 97.95
A:761 [HIS] B:-1 [U] 2.99 B:-16 [U] base:BB base/AA stacks 97.95
A:761 [HIS] B:0 [G] 2.85 C:0 [DC] 97.95
A:761 [HIS] B:1 [G] 4.65 C:-1 [DC] 97.95
A:764 [TYR] B:-1 [U] 4.59 B:-16 [U] 96.96
A:764 [TYR] B:0 [G] 4.54 C:0 [DC] 96.96
A:784 [GLN] B:1 [G] 3.42 C:-1 [DC] base:SC 70.22
A:786 [GLU] B:1 [G] 4.79 C:-1 [DC] 96.51
A:786 [GLU] B:2 [A] 3.3 C:-2 [DT] sugar:SC 96.51
A:788 [PHE] B:2 [A] 3.64 C:-2 [DT] 98.72
A:790 [ARG] B:-16 [U] 4.33 B:-1 [U] 98.94
A:790 [ARG] B:-15 [U] 2.82 B:-2 [A] 98.94
A:798 [MET] B:-19 [A] 3.92 34.63
A:800 [HIS] B:-19 [A] 2.83 92.09
A:806 [MET] B:-19 [A] 3.51 76.03
A:807 [LEU] B:-19 [A] 3.27 41.18
A:807 [LEU] B:-10 [U] 4.71 B:-18 [A] 41.18
A:808 [ASN] B:-19 [A] 3.08 base:SC 82.45
A:808 [ASN] B:-10 [U] 3.61 B:-18 [A] sugar:SC 82.45
A:808 [ASN] B:-9 [C] 2.93 82.45
A:809 [LYS] B:-11 [C] 3.45 B:-6 [G] 79.1
A:809 [LYS] B:-10 [U] 2.8 B:-18 [A] 79.1
A:810 [LYS] B:-11 [C] 3.25 B:-6 [G] 77.75
A:810 [LYS] B:-10 [U] 3.07 B:-18 [A] 77.75
A:814 [GLN] B:-9 [C] 3.84 2.96
A:823 [TYR] B:-19 [A] 3.96 base:SC 72.0
A:850 [ILE] B:-9 [C] 4.32 7.76
A:852 [LYS] B:-19 [A] 3.6 58.96
A:852 [LYS] B:-10 [U] 3.38 B:-18 [A] 58.96
A:852 [LYS] B:-9 [C] 2.84 58.96
A:852 [LYS] B:-8 [U] 2.8 58.96
A:855 [SER] B:-7 [U] 4.25 8.51
A:856 [HIS] B:-18 [A] 3.46 B:-10 [U] 78.43
A:856 [HIS] B:-7 [U] 3.19 base/AA stacks 78.43
A:858 [ILE] B:-19 [A] 3.21 84.69
A:858 [ILE] B:-18 [A] 3.52 B:-10 [U] 84.69
A:859 [ILE] B:-19 [A] 4.77 78.83
A:859 [ILE] B:-18 [A] 3.14 B:-10 [U] 78.83
A:859 [ILE] B:-17 [U] 4.76 78.83
A:860 [LYS] B:-19 [A] 3.95 92.42
A:860 [LYS] B:-18 [A] 3.85 B:-10 [U] 92.42
A:861 [ASP] B:-18 [A] 4.28 B:-10 [U] 88.78
A:861 [ASP] B:-17 [U] 4.21 88.78
A:862 [ARG] B:-18 [A] 3.61 B:-10 [U] 77.11
A:862 [ARG] B:-17 [U] 2.65 77.11
A:863 [ARG] B:-18 [A] 4.4 B:-10 [U] 98.81
A:863 [ARG] B:-17 [U] 2.89 base/AA stacks 98.81
A:863 [ARG] B:-15 [U] 3.41 B:-2 [A] 98.81
A:863 [ARG] B:-14 [C] 2.9 B:-3 [G] 98.81
A:863 [ARG] B:-13 [U] 4.91 B:-4 [A] 98.81
A:864 [PHE] B:-15 [U] 4.25 B:-2 [A] 74.8
A:864 [PHE] B:-14 [C] 3.57 B:-3 [G] 74.8
A:870 [PHE] B:-16 [U] 3.31 B:-1 [U] 72.09
A:870 [PHE] B:-15 [U] 3.82 B:-2 [A] 72.09
A:872 [HIS] B:1 [G] 2.81 C:-1 [DC] sugar:SC 96.51
A:872 [HIS] B:2 [A] 3.54 C:-2 [DT] 96.51
A:874 [PRO] B:0 [G] 3.88 C:0 [DC] 95.21
A:938 [PHE] B:-12 [A] 3.26 B:-5 [U] 72.26
A:938 [PHE] B:-11 [C] 3.75 B:-6 [G] 72.26
A:940 [TYR] B:-13 [U] 2.76 B:-4 [A] sugar:SC 98.17
A:940 [TYR] B:-12 [A] 3.24 B:-5 [U] sugar:SC 98.17
A:943 [LYS] B:-12 [A] 3.87 B:-5 [U] 80.07
A:948 [GLU] B:10 [U] 4.39 C:-10 [DA] 93.25
A:952 [VAL] B:10 [U] 3.84 C:-10 [DA] 49.76
A:952 [VAL] B:11 [G] 3.7 C:-11 [DC] 49.76
A:955 [ARG] B:9 [G] 3.35 C:-9 [DC] base:SC 97.04
A:955 [ARG] B:10 [U] 3.24 C:-10 [DA] 97.04
A:955 [ARG] B:11 [G] 3.54 C:-11 [DC] 97.04
A:956 [GLN] B:11 [G] 3.33 C:-11 [DC] 70.92
A:956 [GLN] B:12 [C] 3.15 C:-12 [DG] 70.92
A:966 [ASP] B:-14 [C] 2.97 B:-3 [G] sugar:BB 80.7
A:966 [ASP] B:-13 [U] 3.46 B:-4 [A] 80.7
A:967 [LEU] B:-14 [C] 4.87 B:-3 [G] 90.85
A:967 [LEU] B:-13 [U] 3.77 B:-4 [A] 90.85
A:967 [LEU] B:-12 [A] 4.1 B:-5 [U] 90.85
A:969 [GLN] B:-14 [C] 4.35 B:-3 [G] 72.94
A:970 [GLY] B:-14 [C] 4.11 B:-3 [G] 98.75
A:970 [GLY] B:-13 [U] 3.3 B:-4 [A] 98.75
A:970 [GLY] B:-3 [G] 4.92 B:-14 [C] 98.75
A:971 [TYR] B:-13 [U] 4.16 B:-4 [A] 97.2
A:973 [SER] B:-3 [G] 3.29 B:-14 [C] base:SC 98.97
A:973 [SER] B:-2 [A] 3.16 B:-15 [U] 98.97
A:974 [GLN] B:-13 [U] 4.44 B:-4 [A] 75.88
A:974 [GLN] B:-4 [A] 4.56 B:-13 [U] 75.88
A:974 [GLN] B:-3 [G] 4.2 B:-14 [C] 75.88
A:976 [ILE] B:-2 [A] 4.74 B:-15 [U] 87.53
A:977 [HIS] B:-3 [G] 3.15 B:-14 [C] 90.41
A:977 [HIS] B:-2 [A] 4.45 B:-15 [U] 90.41
A:1018 [MET] B:-2 [A] 4.74 B:-15 [U] 0.0
A:1018 [MET] B:-1 [U] 4.94 B:-16 [U] 0.0
A:1022 [LYS] B:-2 [A] 4.2 B:-15 [U] 0.0
A:1022 [LYS] B:-1 [U] 2.62 B:-16 [U] 0.0
A:1027 [VAL] B:-2 [A] 4.71 B:-15 [U] 0.0
A:1029 [LYS] B:-3 [G] 2.83 B:-14 [C] 0.0
A:1029 [LYS] B:-2 [A] 3.37 B:-15 [U] 0.0
A:1030 [ASP] B:-3 [G] 4.89 B:-14 [C] 0.0

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group47 5XH6_A_B A: Crispr-associated endonuclease cpf1, Acidaminococcus sp. (strain bv3l6) (genetically engineered) B: crRNA, Acidaminococcus sp. bv3l6 (synthetic) U2UMQ6 CRISPR-associated endonuclease Cpf1 first helical domain & CRISPR-associated endonuclease Cpf1 second helical domain & Small protein B (SmpB) & Ribonuclease H-like ✘

Interologs

Total number of interologs for this interface: 2

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
5XH6_A_B 5XUT_A_B 0.82 0.9 1.42 0.5 CRISPR-associated endonuclease Cpf1 first helical domain & CRISPR-associated endonuclease Cpf1 second helical domain & Small protein B (SmpB) & Ribonuclease H-like compare
5XH6_A_B 5XH7_A_B 1.00 1.0 0.13 0.53 CRISPR-associated endonuclease Cpf1 first helical domain & CRISPR-associated endonuclease Cpf1 second helical domain & Small protein B (SmpB) & Ribonuclease H-like compare