Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Show chains
Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
4ZLD_A
|
4ZLD_B
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:181 [TRP] | B:1 [U] | 3.42 | base/AA stacks | 71.12 | ||
A:185 [ARG] | B:1 [U] | 2.89 | base:SC, sugar:SC | 90.25 | ||
A:185 [ARG] | B:2 [A] | 3.76 | B:16 [U] | 90.25 | ||
A:185 [ARG] | B:3 [A] | 2.85 | B:15 [U] | 90.25 | ||
A:186 [ALA] | B:12 [A] | 4.64 | B:6 [U] | 54.34 | ||
A:187 [ARG] | B:11 [G] | 3.83 | B:7 [C] | 80.12 | ||
A:188 [GLY] | B:11 [G] | 3.97 | B:7 [C] | 61.11 | ||
A:190 [GLN] | B:1 [U] | 4.22 | 85.98 | |||
A:190 [GLN] | B:3 [A] | 3.55 | B:15 [U] | 85.98 | ||
A:191 [PHE] | B:1 [U] | 2.96 | base:BB | 80.91 | ||
A:192 [LEU] | B:1 [U] | 4.4 | 76.6 | |||
A:193 [GLY] | B:1 [U] | 3.94 | 84.65 | |||
A:216 [ARG] | B:8 [U] | 4.78 | 71.65 | |||
A:216 [ARG] | B:9 [G] | 2.91 | base/AA stacks | 71.65 | ||
A:217 [LYS] | B:7 [C] | 3.19 | B:11 [G] | 78.19 | ||
A:217 [LYS] | B:8 [U] | 3.7 | 78.19 | |||
A:233 [GLN] | B:4 [C] | 3.39 | B:14 [G] | 47.52 | ||
A:234 [ALA] | B:4 [C] | 4.86 | B:14 [G] | 63.8 | ||
A:235 [SER] | B:3 [A] | 4.82 | B:15 [U] | 85.91 | ||
A:235 [SER] | B:4 [C] | 2.57 | B:14 [G] | 85.91 | ||
A:235 [SER] | B:5 [U] | 3.79 | B:13 [A] | 85.91 | ||
A:236 [LYS] | B:5 [U] | 3.63 | B:13 [A] | 76.56 | ||
A:236 [LYS] | B:6 [U] | 2.74 | B:12 [A] | 76.56 | ||
A:237 [THR] | B:4 [C] | 3.44 | B:14 [G] | 84.71 | ||
A:237 [THR] | B:5 [U] | 2.65 | B:13 [A] | 84.71 | ||
A:238 [SER] | B:4 [C] | 3.92 | B:14 [G] | 73.81 | ||
A:240 [GLY] | B:9 [G] | 4.92 | 63.35 | |||
A:244 [GLN] | B:9 [G] | 2.87 | base:SC, sugar:SC | 84.14 | ||
A:244 [GLN] | B:10 [U] | 3.38 | 84.14 | |||
A:244 [GLN] | B:11 [G] | 3.41 | B:7 [C] | base/AA stacks | 84.14 | |
A:247 [TYR] | B:8 [U] | 4.93 | 71.84 | |||
A:247 [TYR] | B:9 [G] | 2.68 | 71.84 | |||
A:247 [TYR] | B:10 [U] | 3.7 | 71.84 | |||
A:248 [ARG] | B:10 [U] | 3.31 | 67.96 | |||
A:248 [ARG] | B:11 [G] | 2.81 | B:7 [C] | 67.96 | ||
A:250 [SER] | B:10 [U] | 3.36 | 86.4 | |||
A:254 [VAL] | B:9 [G] | 4.18 | 75.42 | |||
A:257 [ARG] | B:8 [U] | 4.59 | 74.01 | |||
A:259 [GLU] | B:8 [U] | 3.1 | 14.46 | |||
A:260 [ASP] | B:8 [U] | 3.13 | 44.31 | |||
A:261 [SER] | B:7 [C] | 4.99 | B:11 [G] | 79.1 | ||
A:261 [SER] | B:8 [U] | 2.57 | 79.1 | |||
A:262 [SER] | B:8 [U] | 3.06 | sugar:BB | 92.4 | ||
A:262 [SER] | B:9 [G] | 4.43 | 92.4 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group66 | 4ZLD_A_B | A: Roquin-2, Homo sapiens (genetically engineered) B: Homo sapiens (synthetic) | Q9HBD1 | winged | ✘ |
Interologs
Total number of interologs for this interface: 3
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
4ZLD_A_B | 6TQA_A_E | 0.81 | 0.98 | 0.67 | 0.45 | winged | compare | |
4ZLD_A_B | 6TQB_A_B | 0.76 | 0.98 | 0.47 | 0.64 | winged | compare | |
4ZLD_A_B | 5F5H_A_C | 0.71 | 0.94 | 0.59 | 0.33 | winged | compare |