Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
4C8Y_A
|
4C8Y_C
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:19 [LEU] | C:30 [U] | 2.87 | 65.01 | |||
A:20 [GLY] | C:30 [U] | 3.1 | 71.95 | |||
A:21 [LEU] | C:30 [U] | 4.69 | 72.6 | |||
A:22 [ARG] | C:29 [A] | 2.83 | 91.41 | |||
A:23 [GLY] | C:29 [A] | 3.92 | 87.29 | |||
A:23 [GLY] | C:30 [U] | 3.33 | 87.29 | |||
A:24 [PHE] | C:30 [U] | 3.26 | 57.94 | |||
A:26 [TYR] | C:27 [G] | 4.22 | C:18 [C] | 83.39 | ||
A:26 [TYR] | C:29 [A] | 3.36 | 83.39 | |||
A:27 [GLY] | C:29 [A] | 4.88 | 26.47 | |||
A:29 [LEU] | C:29 [A] | 4.76 | 70.5 | |||
A:30 [ARG] | C:29 [A] | 3.61 | 66.53 | |||
A:33 [ALA] | C:29 [A] | 4.79 | 87.51 | |||
A:34 [PRO] | C:29 [A] | 2.96 | base:BB | 64.19 | ||
A:37 [HIS] | C:27 [G] | 3.24 | C:18 [C] | sugar:BB | 99.0 | |
A:37 [HIS] | C:29 [A] | 3.11 | base/AA stacks | 99.0 | ||
A:38 [ASP] | C:27 [G] | 4.43 | C:18 [C] | 52.33 | ||
A:39 [GLN] | C:27 [G] | 3.45 | C:18 [C] | 37.2 | ||
A:40 [GLY] | C:26 [G] | 2.53 | C:19 [C] | sugar:BB | 19.32 | |
A:40 [GLY] | C:27 [G] | 3.22 | C:18 [C] | 19.32 | ||
A:41 [GLU] | C:26 [G] | 4.51 | C:19 [C] | 36.77 | ||
A:41 [GLU] | C:27 [G] | 4.79 | C:18 [C] | 36.77 | ||
A:42 [ASN] | C:27 [G] | 3.22 | C:18 [C] | 84.78 | ||
A:83 [ARG] | C:30 [U] | 2.69 | base:BB | 66.27 | ||
A:84 [LEU] | C:30 [U] | 3.97 | 86.27 | |||
A:85 [GLY] | C:30 [U] | 3.01 | base:BB | 77.68 | ||
A:127 [PHE] | C:26 [G] | 4.89 | C:19 [C] | 81.18 | ||
A:128 [PHE] | C:25 [G] | 4.6 | C:20 [C] | 98.63 | ||
A:128 [PHE] | C:26 [G] | 3.47 | C:19 [C] | 98.63 | ||
A:129 [ARG] | C:17 [C] | 3.64 | C:28 [DG] | 84.01 | ||
A:129 [ARG] | C:18 [C] | 4.34 | C:27 [G] | 84.01 | ||
A:129 [ARG] | C:25 [G] | 3.31 | C:20 [C] | 84.01 | ||
A:129 [ARG] | C:26 [G] | 2.93 | C:19 [C] | base:SC, base:SC | 84.01 | |
A:129 [ARG] | C:27 [G] | 2.65 | C:18 [C] | base:SC, base:SC | 84.01 | |
A:130 [ARG] | C:25 [G] | 4.08 | C:20 [C] | 74.8 | ||
A:131 [LYS] | C:25 [G] | 4.37 | C:20 [C] | 44.79 | ||
A:133 [VAL] | C:15 [A] | 4.07 | 45.19 | |||
A:133 [VAL] | C:16 [G] | 4.81 | 45.19 | |||
A:141 [ARG] | C:24 [A] | 3.49 | C:21 [G] | sugar:SC | 50.2 | |
A:142 [LEU] | C:24 [A] | 4.95 | C:21 [G] | 77.83 | ||
A:142 [LEU] | C:25 [G] | 3.13 | C:20 [C] | 77.83 | ||
A:142 [LEU] | C:26 [G] | 4.55 | C:19 [C] | 77.83 | ||
A:145 [GLU] | C:24 [A] | 4.46 | C:21 [G] | 52.21 | ||
A:145 [GLU] | C:25 [G] | 3.43 | C:20 [C] | sugar:SC | 52.21 | |
A:145 [GLU] | C:26 [G] | 4.5 | C:19 [C] | 52.21 | ||
A:146 [SER] | C:26 [G] | 3.61 | C:19 [C] | 95.54 | ||
A:149 [ARG] | C:25 [G] | 2.63 | C:20 [C] | sugar:SC | 71.59 | |
A:149 [ARG] | C:26 [G] | 3.11 | C:19 [C] | 71.59 | ||
A:186 [GLU] | C:16 [G] | 4.36 | 50.44 | |||
A:187 [VAL] | C:16 [G] | 3.96 | 36.98 | |||
A:224 [GLY] | C:26 [G] | 3.57 | C:19 [C] | 98.95 | ||
A:224 [GLY] | C:27 [G] | 4.36 | C:18 [C] | 98.95 | ||
A:225 [ALA] | C:26 [G] | 4.24 | C:19 [C] | 74.63 | ||
A:225 [ALA] | C:27 [G] | 3.45 | C:18 [C] | 74.63 | ||
A:226 [LYS] | C:27 [G] | 3.04 | C:18 [C] | 86.24 | ||
A:227 [THR] | C:27 [G] | 4.05 | C:18 [C] | 97.34 | ||
A:228 [SER] | C:27 [G] | 4.85 | C:18 [C] | 83.98 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group76 | 4C8Y_A_C | A: Cas6a, Thermus thermophilus (genetically engineered) C: R1 repeat RNA substrate mimic | Q5SM65 | CRISPR transcript (pre-crRNA) processing endoribonuclease-related | ✘ |
Interologs
Total number of interologs for this interface: 4
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
4C8Y_A_C | 4ILL_A_R | 0.32 | 0.77 | 2.74 | 0.03 | CRISPR transcript (pre-crRNA) processing endoribonuclease-related | compare | |
4C8Y_A_C | 6H9H_B_E | 0.33 | 0.64 | 2.28 | 0.13 | CRISPR transcript (pre-crRNA) processing endoribonuclease-related | compare | |
2Y8Y_A_B | 4C8Y_A_C | 0.36 | 0.63 | 3.01 | 0.13 | CRISPR transcript (pre-crRNA) processing endoribonuclease-related | compare | |
4C8Y_A_C | 5H9F_K_L | 0.16 | 0.56 | 2.78 | 0.07 | CRISPR transcript (pre-crRNA) processing endoribonuclease-related | compare |