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All interfaces > All interologs > Interface groups > group130 > 4K4S_A_B,C vs 4K4Z_E_F,G

Interface analysis


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Common contacts -

4K4S_A
4K4S_B,C
4K4Z_E
4K4Z_F,G
Conserved?
A:210 [VAL] B:602 [C] E:210 [VAL] F:602 [C] ✔
A:210 [VAL] B:603 [U] E:210 [VAL] F:603 [U] ✔
A:214 [PRO] B:604 [C] E:214 [PRO] F:604 [C] ✔
A:102 [TYR] C:1305 [G] E:102 [TYR] G:1306 [A] ✔
A:392 [MET] C:1310 [A] E:393 [MET] G:1311 [A] ✔
A:392 [MET] C:1311 [G] E:393 [MET] G:1312 [G] ✔
A:289 [GLY] B:600 [G] E:290 [GLY] F:600 [G] ✔
A:289 [GLY] B:601 [U] E:290 [GLY] F:601 [U] ✔
A:177 [GLU] B:600 [G] E:177 [GLU] F:600 [G] ✔
A:128 [ARG] C:1306 [C] E:128 [ARG] G:1307 [C] ✔
A:128 [ARG] C:1307 [G] E:128 [ARG] G:1308 [G] ✔
A:24 [LYS] B:598 [A] E:24 [LYS] F:598 [A] ✔
A:24 [LYS] B:599 [G] E:24 [LYS] F:599 [G] ✔
A:374 [LEU] C:1311 [G] E:375 [LEU] G:1312 [G] ✔
A:374 [LEU] C:1312 [A] E:375 [LEU] G:1313 [A] ✔
A:108 [GLU] B:603 [U] E:108 [GLU] F:603 [U] ✔
A:108 [GLU] B:604 [C] E:108 [GLU] F:604 [C] ✔
A:20 [PRO] B:598 [A] E:20 [PRO] F:598 [A] ✔
A:20 [PRO] B:599 [G] E:20 [PRO] F:599 [G] ✔
A:107 [LEU] B:602 [C] E:107 [LEU] F:602 [C] ✔
A:107 [LEU] B:603 [U] E:107 [LEU] F:603 [U] ✔
A:178 [ALA] B:600 [G] E:178 [ALA] F:600 [G] ✔
A:329 [ASP] C:1312 [A] E:330 [ASP] G:1313 [A] ✔
A:115 [SER] B:599 [G] E:115 [SER] F:599 [G] ✔
A:115 [SER] B:600 [G] E:115 [SER] F:600 [G] ✔
A:115 [SER] B:601 [U] E:115 [SER] F:601 [U] ✔
A:209 [ALA] B:603 [U] E:209 [ALA] F:603 [U] ✔
A:134 [GLN] C:1305 [G] E:134 [LYS] G:1306 [A] ✔
A:126 [LYS] B:597 [C] E:126 [LYS] F:597 [C] ✔
A:157 [TYR] B:599 [G] E:157 [TYR] F:599 [G] ✔
A:160 [ASP] B:599 [G] E:160 [ASP] F:599 [G] ✔
A:211 [GLY] B:603 [U] E:211 [GLY] F:603 [U] ✔
A:211 [GLY] B:604 [C] E:211 [GLY] F:604 [C] ✔
A:328 [ASP] C:1312 [A] E:329 [ASP] G:1313 [A] ✔
A:121 [VAL] B:599 [G] E:121 [VAL] F:599 [G] ✔
A:22 [LYS] B:599 [G] E:22 [LYS] F:599 [G] ✔
A:405 [LYS] C:1309 [G] E:406 [LYS] G:1310 [G] ✔
A:199 [HIS] B:602 [C] E:199 [HIS] F:602 [C] ✔
A:199 [HIS] B:603 [U] E:199 [HIS] F:603 [U] ✔
A:417 [LEU] C:1309 [G] E:418 [LEU] G:1310 [G] ✔
A:417 [LEU] C:1310 [A] E:418 [LEU] G:1311 [A] ✔
A:412 [ASP] B:607 [G] E:413 [ASP] F:607 [G] ✔
A:412 [ASP] C:1307 [G] E:413 [ASP] G:1308 [G] ✔
A:412 [ASP] C:1308 [A] E:413 [ASP] G:1309 [A] ✔
A:413 [HIS] C:1308 [A] E:414 [HIS] G:1309 [A] ✔
A:413 [HIS] C:1309 [G] E:414 [HIS] G:1310 [G] ✔
A:413 [HIS] C:1310 [A] E:414 [HIS] G:1311 [A] ✔
A:213 [ASP] B:604 [C] E:213 [ASP] F:604 [C] ✔
A:213 [ASP] B:605 [U] E:213 [ASP] F:605 [U] ✔
A:195 [TYR] B:602 [C] E:195 [TYR] F:602 [C] ✔
A:184 [SER] B:601 [U] E:184 [SER] F:601 [U] ✔
A:184 [SER] B:602 [C] E:184 [SER] F:602 [C] ✔
A:456 [ARG] B:607 [G] E:457 [LYS] F:607 [G] ✔
A:112 [LEU] C:1306 [C] E:112 [LEU] G:1307 [C] ✔
A:23 [THR] B:599 [G] E:23 [THR] F:599 [G] ✔
A:327 [GLY] C:1312 [A] E:328 [GLY] G:1313 [A] ✔
A:419 [LEU] B:605 [U] E:420 [LEU] F:605 [U] ✔
A:419 [LEU] B:606 [C] E:420 [LEU] F:606 [C] ✔
A:212 [CYS] B:603 [U] E:212 [CYS] F:603 [U] ✔
A:212 [CYS] B:604 [C] E:212 [CYS] F:604 [C] ✔
A:188 [ARG] B:602 [C] E:188 [ARG] F:602 [C] ✔
A:416 [SER] B:605 [U] E:417 [SER] F:605 [U] ✔
A:416 [SER] B:606 [C] E:417 [SER] F:606 [C] ✔
A:416 [SER] C:1308 [A] E:417 [SER] G:1309 [A] ✔
A:416 [SER] C:1309 [G] E:417 [SER] G:1310 [G] ✔
A:400 [SER] C:1309 [G] E:401 [SER] G:1310 [G] ✔
A:400 [SER] C:1310 [A] E:401 [SER] G:1311 [A] ✔
A:288 [SER] B:600 [G] E:289 [SER] F:600 [G] ✔
A:294 [SER] B:602 [C] E:295 [SER] F:602 [C] ✔
A:294 [SER] C:1312 [A] E:295 [SER] G:1313 [A] ✔
A:291 [SER] B:601 [U] E:292 [SER] F:601 [U] ✔
A:291 [SER] B:602 [C] E:292 [SER] F:602 [C] ✔
A:106 [GLY] B:603 [U] E:106 [GLY] F:603 [U] ✔
A:176 [ILE] B:599 [G] E:176 [ILE] F:599 [G] ✔
A:176 [ILE] B:600 [G] E:176 [ILE] F:600 [G] ✔
A:111 [ASP] B:601 [U] E:111 [ASP] F:601 [U] ✔
A:420 [LEU] C:1309 [G] E:421 [LEU] G:1310 [G] ✔
A:420 [LEU] C:1310 [A] E:421 [LEU] G:1311 [A] ✔
A:114 [THR] B:600 [G] E:114 [THR] F:600 [G] ✔
A:114 [THR] B:601 [U] E:114 [THR] F:601 [U] ✔
A:415 [ARG] B:606 [C] E:416 [ARG] F:606 [C] ✔
A:415 [ARG] B:607 [G] E:416 [ARG] F:607 [G] ✔
A:127 [LYS] B:600 [G] E:127 [LYS] F:600 [G] ✔
A:127 [LYS] B:601 [U] E:127 [LYS] F:601 [U] ✔
A:293 [THR] B:600 [G] E:294 [THR] F:600 [G] ✔
A:293 [THR] B:601 [U] E:294 [THR] F:601 [U] ✔
A:290 [CYS] B:600 [G] E:291 [CYS] F:600 [G] ✔
A:290 [CYS] B:601 [U] E:291 [CYS] F:601 [U] ✔
A:18 [ASN] B:598 [A] E:18 [ASN] F:598 [A] ✔
A:292 [GLY] B:601 [U] E:293 [GLY] F:601 [U] ✔
A:326 [TYR] B:602 [C] E:327 [TYR] F:602 [C] ✔
A:326 [TYR] B:603 [U] E:327 [TYR] F:603 [U] ✔
A:326 [TYR] C:1311 [G] E:327 [TYR] G:1312 [G] ✔
A:326 [TYR] C:1312 [A] E:327 [TYR] G:1313 [A] ✔
A:113 [SER] B:600 [G] E:113 [THR] F:600 [G] ✔
A:113 [SER] C:1307 [G] E:113 [THR] G:1308 [G] ✔
A:110 [LEU] B:602 [C] E:110 [LEU] F:602 [C] ✔
A:133 [LYS] C:1305 [G] E:133 [LYS] G:1306 [A] ✔
A:133 [LYS] C:1306 [C] E:133 [LYS] G:1307 [C] ✔
A:396 [GLU] C:1311 [G] E:397 [ASP] G:1312 [G] ✔
A:409 [ASN] C:1307 [G] E:410 [ASN] G:1308 [G] ✔
A:409 [ASN] C:1308 [A] E:410 [ASN] G:1309 [A] ✔
A:409 [ASN] C:1309 [G] E:410 [ASN] G:1310 [G] ✔
A:375 [LYS] C:1311 [G] E:376 [LYS] G:1312 [G] ✔
A:375 [LYS] C:1312 [A] E:376 [LYS] G:1313 [A] ✔
A:179 [SER] B:600 [G] E:179 [SER] F:600 [G] ✔
A:179 [SER] B:601 [U] E:179 [SER] F:601 [U] ✔
A:43 [LEU] B:599 [G] E:43 [LEU] F:599 [G] ✔
A:159 [LYS] B:600 [G] E:159 [LYS] F:600 [G] ✔
A:159 [LYS] C:1312 [A] E:159 [LYS] G:1313 [A] ✔
A:376 [ARG] C:1310 [A] E:377 [ARG] G:1311 [A] ✔
A:376 [ARG] C:1311 [G] E:377 [ARG] G:1312 [G] ✔
A:126 [LYS] B:598 [A] E:126 [LYS] F:598 [A] ❌ 4K4Z_E_F,G
A:126 [LYS] B:599 [G] E:126 [LYS] F:599 [G] ❌ 4K4Z_E_F,G
A:22 [LYS] B:598 [A] E:22 [LYS] F:598 [A] ❌ 4K4Z_E_F,G
A:456 [ARG] B:606 [C] E:457 [LYS] F:606 [C] ❌ 4K4Z_E_F,G
A:288 [SER] B:601 [U] E:289 [SER] F:601 [U] ❌ 4K4Z_E_F,G
A:114 [THR] B:599 [G] E:114 [THR] F:599 [G] ❌ 4K4Z_E_F,G
A:121 [VAL] B:598 [A] E:121 [VAL] F:598 [A] ❌ 4K4S_A_B,C
A:128 [ARG] C:1305 [G] E:128 [ARG] G:1306 [A] ❌ 4K4S_A_B,C
A:157 [TYR] B:598 [A] E:157 [TYR] F:598 [A] ❌ 4K4S_A_B,C
A:188 [ARG] B:601 [U] E:188 [ARG] F:601 [U] ❌ 4K4S_A_B,C
A:292 [GLY] B:602 [C] E:293 [GLY] F:602 [C] ❌ 4K4S_A_B,C
A:294 [SER] B:601 [U] E:295 [SER] F:601 [U] ❌ 4K4S_A_B,C
A:412 [ASP] C:1309 [G] E:413 [ASP] G:1310 [G] ❌ 4K4S_A_B,C
A:134 [GLN] C:1304 [C] E:134 [LYS] G:1305 [G] ❌ 4K4Z_G:693 no longer at interface
A:133 [LYS] C:1304 [C] E:133 [LYS] G:1305 [G] ❌ 4K4Z_G:693 no longer at interface
A:109 [ALA] B:602 [C] E:109 [ALA] F:602 [C] ❌ 4K4Z_E:109 no longer at interface
A:19 [ALA] B:598 [A] E:19 [THR] F:598 [A] ❌ 4K4Z_E:19 no longer at interface
A:158 [VAL] B:599 [G] E:158 [VAL] F:599 [G] ❌ 4K4S_A:158 no longer at interface
A:17 [ILE] B:598 [A] E:17 [ILE] F:598 [A] ❌ 4K4S_A:17 no longer at interface
A:408 [ARG] C:1307 [G] E:409 [LYS] G:1308 [G] ❌ 4K4S_A:408 no longer at interface
A:408 [ARG] C:1308 [A] E:409 [LYS] G:1309 [A] ❌ 4K4S_A:408 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases 0.99 0.41 0.91 0.99 0.61 0.97 1.0 0.95 0.93 0.56 0.38


Other pairs involving 4K4S_A_B,C or 4K4Z_E_F,G

Total number of entries: 18

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4K4Z_E_F,G 7AAP_A_T 0.61 0.79 1.77 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
4K4Z_E_F,G 6LSG_A_B,C 0.80 0.99 0.69 0.8 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 7BV2_A_T 0.60 0.79 1.53 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
4K4Z_E_F,G 5F8H_A_B,C 0.95 0.99 0.39 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 6KWQ_A_B,C 0.92 0.98 0.55 0.77 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 6LSF_A_B,C 0.87 0.99 0.7 0.44 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4Z_E_F,G 5Y6Z_A_B,C 0.90 0.98 0.73 0.87 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 7AAP_A_T 0.66 0.79 1.85 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
4K4S_A_B,C 5F8H_A_B,C 0.92 0.99 0.44 0.85 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 5Y6Z_A_B,C 0.88 0.98 0.8 0.87 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 4K4Z_E_F,G 0.95 0.99 0.41 0.91 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 6LSG_A_B,C 0.80 0.99 0.75 0.82 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 6LSF_A_B,C 0.87 0.98 0.74 0.5 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 6KWQ_A_B,C 0.92 0.98 0.61 0.79 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
4K4S_A_B,C 7BV2_A_T 0.60 0.79 1.56 0.0 Adenylyl and guanylyl cyclase catalytic domain-like compare
3OL9_A_B,C 4K4Z_E_F,G 0.95 0.99 0.51 0.92 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3OL9_A_B,C 4K4S_A_B,C 0.96 0.99 0.44 0.95 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare
3AVX_A_G,T 4K4Z_E_F,G 0.61 0.61 2.51 0.09 Adenylyl and guanylyl cyclase catalytic domain-like & helical bundle domain in reverse transcriptase-like polymerases compare