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All interfaces > All interologs > Interface groups > group140 > 4Z4D_A_B,D vs 5JS1_A_B

Interface analysis


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Common contacts -

4Z4D_A
4Z4D_B,D
5JS1_A
5JS1_B
Conserved?
A:757 [GLN] B:5 [C] A:757 [GLN] B:5 [C] ✔
A:757 [GLN] B:6 [A] A:757 [GLN] B:6 [U] ✔
A:709 [LYS] B:5 [C] A:709 [LYS] B:5 [C] ✔
A:709 [LYS] B:6 [A] A:709 [LYS] B:6 [U] ✔
A:812 [ARG] B:1 [U] A:812 [ARG] B:1 [U] ✔
A:790 [TYR] B:3 [C] A:790 [TYR] B:3 [A] ✔
A:790 [TYR] B:4 [A] A:790 [TYR] B:4 [U] ✔
A:566 [LYS] B:1 [U] A:566 [LYS] B:1 [U] ✔
A:566 [LYS] B:2 [U] A:566 [LYS] B:2 [U] ✔
A:566 [LYS] B:3 [C] A:566 [LYS] B:3 [A] ✔
A:797 [VAL] B:4 [A] A:797 [VAL] B:4 [U] ✔
A:797 [VAL] B:5 [C] A:797 [VAL] B:5 [C] ✔
A:755 [GLY] B:5 [C] A:755 [GLY] B:5 [C] ✔
A:754 [ALA] B:5 [C] A:754 [ALA] B:5 [C] ✔
A:221 [ALA] B:8 [U] A:221 [ALA] B:8 [U] ✔
A:351 [ARG] B:9 [G] A:351 [ARG] B:9 [A] ✔
A:710 [ARG] B:9 [G] A:710 [ARG] B:9 [A] ✔
A:562 [ASN] B:2 [U] A:562 [ASN] B:2 [U] ✔
A:562 [ASN] B:3 [C] A:562 [ASN] B:3 [A] ✔
A:545 [GLN] B:1 [U] A:545 [GLN] B:1 [U] ✔
A:545 [GLN] B:2 [U] A:545 [GLN] B:2 [U] ✔
A:793 [CYS] B:3 [C] A:793 [CYS] B:3 [A] ✔
A:793 [CYS] B:4 [A] A:793 [CYS] B:4 [U] ✔
A:526 [THR] B:1 [U] A:526 [THR] B:1 [U] ✔
A:375 [ARG] B:7 [U] A:375 [ARG] B:7 [A] ✔
A:753 [HIS] B:5 [C] A:753 [HIS] B:5 [C] ✔
A:753 [HIS] B:6 [A] A:753 [HIS] B:6 [U] ✔
A:522 [LEU] B:1 [U] A:522 [LEU] B:1 [U] ✔
A:220 [SER] B:8 [U] A:220 [SER] B:8 [U] ✔
A:563 [LEU] B:2 [U] A:563 [LEU] B:2 [U] ✔
A:798 [SER] B:4 [A] A:798 [SER] B:4 [U] ✔
A:798 [SER] B:5 [C] A:798 [SER] B:5 [C] ✔
A:798 [SER] B:6 [A] A:798 [SER] B:6 [U] ✔
A:558 [GLN] B:2 [U] A:558 [GLN] B:2 [U] ✔
A:714 [ARG] B:7 [U] A:714 [ARG] B:7 [A] ✔
A:559 [THR] B:2 [U] A:559 [THR] B:2 [U] ✔
A:804 [TYR] B:4 [A] A:804 [TYR] B:4 [U] ✔
A:804 [TYR] B:5 [C] A:804 [TYR] B:5 [C] ✔
A:364 [MET] B:7 [U] A:364 [MET] B:7 [A] ✔
A:815 [TYR] B:1 [U] A:815 [TYR] B:1 [U] ✔
A:756 [ILE] B:4 [A] A:756 [ILE] B:4 [U] ✔
A:756 [ILE] B:5 [C] A:756 [ILE] B:5 [C] ✔
A:547 [VAL] B:1 [U] A:547 [VAL] B:1 [U] ✔
A:547 [VAL] B:2 [U] A:547 [VAL] B:2 [U] ✔
A:859 [ALA] B:1 [U] A:859 [ALA] B:1 [U] ✔
A:859 [ALA] B:3 [C] A:859 [ALA] B:3 [A] ✔
A:799 [ILE] B:5 [C] A:799 [ILE] B:5 [C] ✔
A:529 [TYR] B:1 [U] A:529 [TYR] B:1 [U] ✔
A:570 [LYS] B:1 [U] A:570 [LYS] B:1 [U] ✔
A:368 [THR] B:7 [U] A:368 [THR] B:7 [A] ✔
A:760 [SER] B:5 [C] A:760 [SER] B:5 [C] ✔
A:760 [SER] B:6 [A] A:760 [SER] B:6 [U] ✔
A:792 [ARG] B:3 [C] A:792 [ARG] B:3 [A] ✔
A:792 [ARG] B:4 [A] A:792 [ARG] B:4 [U] ✔
A:761 [ARG] B:6 [A] A:761 [ARG] B:6 [U] ✔
A:761 [ARG] B:7 [U] A:761 [ARG] B:7 [A] ✔
A:761 [ARG] B:8 [U] A:761 [ARG] B:8 [U] ✔
A:365 [ILE] B:6 [A] A:365 [ILE] B:6 [U] ✔
A:365 [ILE] B:7 [U] A:365 [ILE] B:7 [A] ✔
A:758 [GLY] B:6 [A] A:758 [GLY] B:6 [U] ✔
A:759 [THR] B:6 [A] A:759 [THR] B:6 [U] ✔
A:759 [THR] B:7 [U] A:759 [THR] B:7 [A] ✔
A:795 [ARG] B:4 [A] A:795 [ARG] B:4 [U] ✔
A:551 [ASN] B:2 [U] A:551 [ASN] B:2 [U] ✔
A:546 [CYS] B:1 [U] A:546 [CYS] B:1 [U] ✔
A:546 [CYS] B:2 [U] A:546 [CYS] B:2 [U] ✔
A:544 [THR] B:1 [U] A:544 [THR] B:1 [U] ✔
A:548 [GLN] B:1 [U] A:548 [GLN] B:1 [U] ✔
A:548 [GLN] B:2 [U] A:548 [GLN] B:2 [U] ✔
A:525 [LYS] B:1 [U] A:525 [LYS] B:1 [U] ✔
A:533 [LYS] B:1 [U] A:533 [LYS] B:1 [U] ✔
A:524 [GLY] B:1 [U] A:524 [GLY] B:1 [U] ✔
A:710 [ARG] B:8 [U] A:710 [ARG] B:8 [U] ❌ 5JS1_A_B
A:551 [ASN] B:1 [U] A:551 [ASN] B:1 [U] ❌ 5JS1_A_B
A:177 [VAL] B:9 [G] A:177 [VAL] B:9 [A] ❌ 4Z4D_A_B,D
A:220 [SER] B:7 [U] A:220 [SER] B:7 [A] ❌ 4Z4D_A_B,D
A:221 [ALA] B:7 [U] A:221 [ALA] B:7 [A] ❌ 4Z4D_A_B,D
A:361 [THR] B:7 [U] A:361 [THR] B:7 [A] ❌ 4Z4D_A_B,D
A:364 [MET] B:8 [U] A:364 [MET] B:8 [U] ❌ 4Z4D_A_B,D
A:714 [ARG] B:6 [A] A:714 [ARG] B:6 [U] ❌ 4Z4D_A_B,D
A:714 [ARG] B:8 [U] A:714 [ARG] B:8 [U] ❌ 4Z4D_A_B,D
A:761 [ARG] B:5 [C] A:761 [ARG] B:5 [C] ❌ 4Z4D_A_B,D
A:602 [PRO] B:9 [G] A:602 [PRO] B:9 [A] ❌ 5JS1_A:602 no longer at interface
A:219 [VAL] B:8 [U] A:219 [VAL] B:8 [U] ❌ 4Z4D_A:219 no longer at interface
A:222 [THR] B:8 [U] A:222 [THR] B:8 [U] ❌ 4Z4D_A:222 no longer at interface
A:222 [THR] B:9 [G] A:222 [THR] B:9 [A] ❌ 4Z4D_A:222 no longer at interface
A:222 [THR] B:7 [U] A:222 [THR] B:7 [A] ❌ 4Z4D_A:222 no longer at interface
A:223 [ALA] B:8 [U] A:223 [ALA] B:8 [U] ❌ 4Z4D_A:223 no longer at interface
A:352 [CYS] B:8 [U] A:352 [CYS] B:8 [U] ❌ 4Z4D_A:352 no longer at interface
A:353 [ILE] B:9 [G] A:353 [ILE] B:9 [A] ❌ 4Z4D_A:353 no longer at interface
A:356 [LEU] B:7 [U] A:356 [LEU] B:7 [A] ❌ 4Z4D_A:356 no longer at interface
A:369 [ALA] B:6 [A] A:369 [ALA] B:6 [U] ❌ 4Z4D_A:369 no longer at interface
A:369 [ALA] B:7 [U] A:369 [ALA] B:7 [A] ❌ 4Z4D_A:369 no longer at interface
A:712 [HIS] B:8 [U] A:712 [HIS] B:8 [U] ❌ 4Z4D_A:712 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs 0.92 3.21 0.40 0.92 0.46 0.84 0.9 0.90 0.79 0.70 0.55


Other pairs involving 4Z4D_A_B,D or 5JS1_A_B

Total number of entries: 35

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 4Z4D_A_B,D 0.95 0.93 3.04 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4OLA_A_B 5JS1_A_B 0.99 1.0 0.31 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KXT_A_B 5JS1_A_B 0.97 0.98 0.84 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4Z4D_A_B,D 0.87 0.91 2.97 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 4Z4D_A_B,D 0.86 0.94 2.2 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRE_A_R 5JS1_A_B 0.98 0.97 1.31 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6MFN_A_C,E 0.86 0.86 1.83 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
5JS1_A_B 6OZS_B_C,D 0.52 0.61 2.68 0.0 Ribonuclease H-like compare
5JS1_A_B 6OZS_A_C,D 0.58 0.61 2.63 0.0 Ribonuclease H-like compare
5JS1_A_B 6D92_A_C 0.60 0.71 3.43 0.15 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6CBD_A_B,C 0.91 0.91 3.24 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OON_A_B 0.98 0.96 1.74 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5JS1_A_B 6OZP_B_C,D 0.50 0.61 2.67 0.05 Ribonuclease H-like compare
5JS1_A_B 6OZP_A_C,D 0.58 0.61 2.68 0.1 Ribonuclease H-like compare
5AWH_A_C 5JS1_A_B 0.62 0.71 4.1 0.16 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6MFN_A_C,E 0.85 0.92 1.69 0.76 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5AWH_A_C 0.59 0.71 4.13 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OZS_B_C,D 0.49 0.63 2.83 0.14 Ribonuclease H-like compare
4Z4D_A_B,D 6D92_A_C 0.59 0.71 4.22 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OON_A_B 0.90 0.96 1.83 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6CBD_A_B,C 0.95 1.0 0.3 0.93 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OZP_A_C,D 0.56 0.61 2.76 0.15 Ribonuclease H-like compare
4Z4D_A_B,D 5JS1_A_B 0.90 0.92 3.21 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6OZS_A_C,D 0.58 0.6 2.77 0.15 Ribonuclease H-like compare
4Z4D_A_B,D 6OZP_B_C,D 0.48 0.63 2.69 0.1 Ribonuclease H-like compare
4W5O_A_B,D 5JS1_A_B 0.88 0.92 3.24 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 4Z4D_A_B,D 0.96 1.0 0.12 0.96 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 4Z4D_A_B,D 0.88 0.93 2.36 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5JS1_A_B 0.98 0.98 1.05 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 4Z4D_A_B,D 0.91 0.99 0.27 0.88 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5JS1_A_B 0.87 0.92 3.34 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 5JS1_A_B 0.98 0.99 0.4 0.3 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4Z4D_A_B,D 0.70 0.92 3.19 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare