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All interfaces > All interologs > Interface groups > group140 > 6D92_A_C vs 6MFN_A_C,E

Interface analysis


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Common contacts -

6D92_A
6D92_C
6MFN_A
6MFN_C,E
Conserved?
A:494 [TYR] C:2 [U] A:558 [GLN] C:2 [U] ✔
A:731 [ARG] C:3 [A] A:792 [ARG] C:3 [C] ✔
A:731 [ARG] C:4 [C] A:792 [ARG] C:4 [A] ✔
A:499 [PHE] C:2 [U] A:563 [LEU] C:2 [U] ✔
A:777 [LEU] C:1 [U] A:859 [ALA] C:1 [U] ✔
A:777 [LEU] C:3 [A] A:859 [ALA] C:3 [C] ✔
A:463 [TYR] C:1 [U] A:529 [TYR] C:1 [U] ✔
A:449 [LEU] C:1 [U] A:522 [LEU] C:1 [U] ✔
A:484 [THR] C:1 [U] A:551 [ASN] C:1 [U] ✔
A:484 [THR] C:2 [U] A:551 [ASN] C:2 [U] ✔
A:480 [VAL] C:1 [U] A:547 [VAL] C:1 [U] ✔
A:480 [VAL] C:2 [U] A:547 [VAL] C:2 [U] ✔
A:686 [ASN] C:5 [U] A:753 [HIS] C:5 [C] ✔
A:686 [ASN] C:6 [G] A:753 [HIS] C:6 [A] ✔
A:737 [ALA] C:4 [C] A:798 [SER] C:4 [A] ✔
A:737 [ALA] C:5 [U] A:798 [SER] C:5 [C] ✔
A:736 [ALA] C:4 [C] A:797 [VAL] C:4 [A] ✔
A:736 [ALA] C:5 [U] A:797 [VAL] C:5 [C] ✔
A:479 [GLN] C:1 [U] A:546 [CYS] C:1 [U] ✔
A:479 [GLN] C:2 [U] A:546 [CYS] C:2 [U] ✔
A:478 [GLN] C:1 [U] A:545 [GLN] C:1 [U] ✔
A:478 [GLN] C:2 [U] A:545 [GLN] C:2 [U] ✔
A:467 [LYS] C:1 [U] A:533 [LYS] C:1 [U] ✔
A:697 [PRO] C:6 [G] A:758 [GLY] C:6 [A] ✔
A:697 [PRO] C:7 [C] A:758 [GLY] C:7 [G] ✔
A:696 [THR] C:5 [U] A:757 [GLN] C:5 [C] ✔
A:696 [THR] C:6 [G] A:757 [GLN] C:6 [A] ✔
A:692 [LYS] C:4 [C] A:756 [ILE] C:4 [A] ✔
A:692 [LYS] C:5 [U] A:756 [ILE] C:5 [C] ✔
A:175 [GLY] C:8 [A] A:220 [SER] C:8 [U] ✔
A:754 [ARG] C:1 [U] A:815 [TYR] C:1 [U] ✔
A:481 [ARG] C:1 [U] A:548 [GLN] C:1 [U] ✔
A:481 [ARG] C:2 [U] A:548 [GLN] C:2 [U] ✔
A:699 [PRO] C:6 [G] A:760 [SER] C:6 [A] ✔
A:506 [LYS] C:1 [U] A:570 [LYS] C:1 [U] ✔
A:498 [ASN] C:2 [U] A:562 [ASN] C:2 [U] ✔
A:498 [ASN] C:3 [A] A:562 [ASN] C:3 [C] ✔
A:455 [ARG] C:1 [U] A:526 [THR] C:1 [U] ✔
A:495 [THR] C:2 [U] A:559 [THR] C:2 [U] ✔
A:734 [LEU] C:4 [C] A:795 [ARG] C:4 [A] ✔
A:477 [THR] C:1 [U] A:544 [THR] C:1 [U] ✔
A:176 [MET] C:8 [A] A:221 [ALA] C:8 [U] ✔
A:732 [SER] C:3 [A] A:793 [CYS] C:3 [C] ✔
A:732 [SER] C:4 [C] A:793 [CYS] C:4 [A] ✔
A:454 [ALA] C:1 [U] A:525 [LYS] C:1 [U] ✔
A:743 [PHE] C:4 [C] A:804 [TYR] C:4 [A] ✔
A:731 [ARG] C:2 [U] A:792 [ARG] C:2 [U] ❌ 6MFN_A_C,E
A:478 [GLN] C:3 [A] A:545 [GLN] C:3 [C] ❌ 6MFN_A_C,E
A:176 [MET] C:7 [C] A:221 [ALA] C:7 [G] ❌ 6MFN_A_C,E
A:696 [THR] C:4 [C] A:757 [GLN] C:4 [A] ❌ 6D92_A_C
A:737 [ALA] C:6 [G] A:798 [SER] C:6 [A] ❌ 6D92_A_C
A:743 [PHE] C:5 [U] A:804 [TYR] C:5 [C] ❌ 6D92_A_C
A:461 [ASN] C:1 [U] A:527 [PRO] C:1 [U] ❌ 6MFN_A:527 no longer at interface
A:245 [LYS] C:6 [G] A:354 [LYS] C:6 [A] ❌ 6MFN_A:354 no longer at interface
A:245 [LYS] C:7 [C] A:354 [LYS] C:7 [G] ❌ 6MFN_A:354 no longer at interface
A:245 [LYS] C:8 [A] A:354 [LYS] C:8 [U] ❌ 6MFN_A:354 no longer at interface
A:178 [TYR] C:7 [C] A:223 [ALA] C:7 [G] ❌ 6MFN_A:223 no longer at interface
A:178 [TYR] C:8 [A] A:223 [ALA] C:8 [U] ❌ 6MFN_A:223 no longer at interface
A:177 [ARG] C:8 [A] A:222 [THR] C:8 [U] ❌ 6MFN_A:222 no longer at interface
A:243 [GLY] C:8 [A] A:352 [CYS] C:8 [U] ❌ 6MFN_A:352 no longer at interface
A:735 [PRO] C:4 [C] A:796 [SER] C:4 [A] ❌ 6MFN_A:796 no longer at interface
A:735 [PRO] C:5 [U] A:796 [SER] C:5 [C] ❌ 6MFN_A:796 no longer at interface
A:244 [SER] C:8 [A] A:353 [ILE] C:8 [U] ❌ 6MFN_A:353 no longer at interface
A:487 [LEU] C:2 [U] A:554 [ARG] C:2 [U] ❌ 6MFN_A:554 no longer at interface
A:151 [ARG] C:8 [A] A:201 [GLY] C:8 [U] ❌ 6MFN_A:201 no longer at interface
A:275 [ARG] C:7 [C] A:370 [ARG] C:7 [G] ❌ 6MFN_A:370 no longer at interface
A:275 [ARG] C:8 [A] A:370 [ARG] C:8 [U] ❌ 6MFN_A:370 no longer at interface
A:271 [GLU] C:7 [C] A:368 [THR] C:7 [G] ❌ 6D92_A:271 no longer at interface
A:271 [GLU] C:8 [A] A:368 [THR] C:8 [U] ❌ 6D92_A:271 no longer at interface
A:272 [ALA] C:7 [C] A:369 [ALA] C:7 [G] ❌ 6D92_A:272 no longer at interface
A:272 [ALA] C:6 [G] A:369 [ALA] C:6 [A] ❌ 6D92_A:272 no longer at interface
A:280 [PHE] C:7 [C] A:375 [ARG] C:7 [G] ❌ 6D92_A:280 no longer at interface
A:451 [GLU] C:1 [U] A:524 [GLY] C:1 [U] ❌ 6D92_A:451 no longer at interface
A:502 [ALA] C:1 [U] A:566 [LYS] C:1 [U] ❌ 6D92_A:502 no longer at interface
A:502 [ALA] C:3 [A] A:566 [LYS] C:3 [C] ❌ 6D92_A:502 no longer at interface
A:502 [ALA] C:2 [U] A:566 [LYS] C:2 [U] ❌ 6D92_A:502 no longer at interface
A:639 [HIS] C:6 [G] A:709 [LYS] C:6 [A] ❌ 6D92_A:639 no longer at interface
A:640 [ASP] C:8 [A] A:710 [ARG] C:8 [U] ❌ 6D92_A:640 no longer at interface
A:644 [VAL] C:7 [C] A:714 [ARG] C:7 [G] ❌ 6D92_A:644 no longer at interface
A:644 [VAL] C:6 [G] A:714 [ARG] C:6 [A] ❌ 6D92_A:644 no longer at interface
A:687 [SER] C:5 [U] A:754 [ALA] C:5 [C] ❌ 6D92_A:687 no longer at interface
A:691 [ILE] C:5 [U] A:755 [GLY] C:5 [C] ❌ 6D92_A:691 no longer at interface
A:698 [LEU] C:7 [C] A:759 [THR] C:7 [G] ❌ 6D92_A:698 no longer at interface
A:698 [LEU] C:6 [G] A:759 [THR] C:6 [A] ❌ 6D92_A:698 no longer at interface
A:700 [THR] C:7 [C] A:761 [ARG] C:7 [G] ❌ 6D92_A:700 no longer at interface
A:700 [THR] C:6 [G] A:761 [ARG] C:6 [A] ❌ 6D92_A:700 no longer at interface
A:700 [THR] C:8 [A] A:761 [ARG] C:8 [U] ❌ 6D92_A:700 no longer at interface
A:729 [SER] C:3 [A] A:790 [TYR] C:3 [C] ❌ 6D92_A:729 no longer at interface
A:729 [SER] C:4 [C] A:790 [TYR] C:4 [A] ❌ 6D92_A:729 no longer at interface
A:738 [THR] C:5 [U] A:799 [ILE] C:5 [C] ❌ 6D92_A:738 no longer at interface
A:751 [LEU] C:1 [U] A:812 [ARG] C:1 [U] ❌ 6D92_A:751 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs 0.7 2.72 0.12 0.71 0.23 0.59 0.47 0.65 0.65 0.18 0.87


Other pairs involving 6D92_A_C or 6MFN_A_C,E

Total number of entries: 29

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4OLA_A_B 6MFN_A_C,E 0.88 0.86 1.81 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4OLA_A_B 6D92_A_C 0.61 0.7 3.32 0.1 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6MFN_A_C,E 6OZP_A_C,D 0.59 0.61 2.53 0.1 Ribonuclease H-like compare
6MFN_A_C,E 6OON_A_B 0.88 0.89 1.67 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
6MFN_A_C,E 6OZP_B_C,D 0.47 0.63 2.56 0.05 Ribonuclease H-like compare
6MFN_A_C,E 6OZS_A_C,D 0.59 0.61 2.51 0.1 Ribonuclease H-like compare
6MFN_A_C,E 6OZS_B_C,D 0.42 0.63 2.57 0.09 Ribonuclease H-like compare
4KXT_A_B 6D92_A_C 0.48 0.71 3.26 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6MFN_A_C,E 0.90 0.85 1.72 0.17 Ribonuclease H-like & Argonaute, N-terminal domain compare
4KRE_A_R 6MFN_A_C,E 0.86 0.87 1.83 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4KRE_A_R 6D92_A_C 0.62 0.7 3.92 0.09 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6D92_A_C 6OON_A_B 0.64 0.7 3.88 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6D92_A_C 6MFN_A_C,E 0.65 0.7 2.72 0.12 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
5JS1_A_B 6MFN_A_C,E 0.86 0.86 1.83 0.4 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
5JS1_A_B 6D92_A_C 0.60 0.71 3.43 0.15 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6D92_A_C 0.99 1.0 0.3 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5AWH_A_C 6MFN_A_C,E 0.67 0.7 2.74 0.18 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6MFN_A_C,E 0.85 0.92 1.69 0.76 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 6D92_A_C 0.59 0.71 4.22 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6MFN_A_C,E 0.85 0.92 1.55 0.76 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4W5O_A_B,D 6D92_A_C 0.59 0.71 4.07 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 6D92_A_C 0.62 0.71 4.01 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 6MFN_A_C,E 0.87 0.86 1.85 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6D92_A_C 0.53 0.71 3.89 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 6MFN_A_C,E 0.83 0.93 1.53 0.59 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
4F3T_A_R 6D92_A_C 0.53 0.71 3.42 0.14 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 6MFN_A_C,E 0.84 0.85 1.9 0.21 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6D92_A_C 0.57 0.71 3.31 0.11 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
6CBD_A_B,C 6MFN_A_C,E 0.83 0.92 1.43 0.76 Ribonuclease H-like & Argonaute, N-terminal domain & Middle domain in Argonaute homologs compare