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All interfaces > All interologs > Interface groups > group140 > 4KXT_A_B vs 5I4A_A_B

Interface analysis


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Common contacts -

4KXT_A
4KXT_B
5I4A_A
5I4A_B
Conserved?
A:527 [TYR] B:1 [A] A:383 [ILE] B:1 [U] ✔
A:790 [ARG] B:3 [A] A:608 [SER] B:3 [U] ✔
A:790 [ARG] B:4 [A] A:608 [SER] B:4 [A] ✔
A:791 [CYS] B:3 [A] A:609 [THR] B:3 [U] ✔
A:544 [CYS] B:1 [A] A:398 [PRO] B:1 [U] ✔
A:544 [CYS] B:2 [A] A:398 [PRO] B:2 [A] ✔
A:560 [ASN] B:2 [A] A:414 [SER] B:2 [A] ✔
A:813 [TYR] B:1 [A] A:632 [GLU] B:1 [U] ✔
A:802 [TYR] B:4 [A] A:621 [HIS] B:4 [A] ✔
A:545 [VAL] B:1 [A] A:399 [ILE] B:1 [U] ✔
A:545 [VAL] B:2 [A] A:399 [ILE] B:2 [A] ✔
A:796 [SER] B:4 [A] A:615 [LYS] B:4 [A] ✔
A:793 [ARG] B:4 [A] A:612 [THR] B:4 [A] ✔
A:520 [LEU] B:1 [A] A:376 [LEU] B:1 [U] ✔
A:522 [GLY] B:1 [A] A:378 [LYS] B:1 [U] ✔
A:557 [THR] B:2 [A] A:411 [ILE] B:2 [A] ✔
A:564 [LYS] B:1 [A] A:418 [LYS] B:1 [U] ✔
A:564 [LYS] B:2 [A] A:418 [LYS] B:2 [A] ✔
A:564 [LYS] B:3 [A] A:418 [LYS] B:3 [U] ✔
A:795 [VAL] B:4 [A] A:614 [TYR] B:4 [A] ✔
A:524 [THR] B:1 [A] A:380 [ILE] B:1 [U] ✔
A:561 [LEU] B:2 [A] A:415 [TYR] B:2 [A] ✔
A:556 [GLN] B:2 [A] A:410 [PHE] B:2 [A] ✔
A:754 [ILE] B:4 [A] A:573 [PHE] B:4 [A] ✔
A:546 [GLN] B:1 [A] A:400 [LEU] B:1 [U] ✔
A:546 [GLN] B:2 [A] A:400 [LEU] B:2 [A] ✔
A:523 [LYS] B:1 [A] A:379 [TYR] B:1 [U] ✔
A:549 [ASN] B:2 [A] A:403 [LYS] B:2 [A] ✔
A:791 [CYS] B:4 [A] A:609 [THR] B:4 [A] ❌ 5I4A_A_B
A:560 [ASN] B:3 [A] A:414 [SER] B:3 [U] ❌ 5I4A_A_B
A:218 [SER] B:8 [A] A:148 [LYS] B:8 [C] ❌ 5I4A_A_B
A:549 [ASN] B:1 [A] A:403 [LYS] B:1 [U] ❌ 5I4A_A_B
A:178 [SER] B:8 [A] A:108 [ASN] B:8 [C] ❌ 4KXT_A_B
A:523 [LYS] B:4 [A] A:379 [TYR] B:4 [A] ❌ 4KXT_A_B
A:549 [ASN] B:3 [A] A:403 [LYS] B:3 [U] ❌ 4KXT_A_B
A:755 [GLN] B:4 [A] A:574 [LEU] B:4 [A] ❌ 4KXT_A_B
A:791 [CYS] B:2 [A] A:609 [THR] B:2 [A] ❌ 4KXT_A_B
A:793 [ARG] B:3 [A] A:612 [THR] B:3 [U] ❌ 4KXT_A_B
A:810 [ARG] B:1 [A] A:629 [THR] B:1 [U] ❌ 5I4A_A:629 no longer at interface
A:710 [HIS] B:8 [A] A:547 [ASN] B:8 [C] ❌ 5I4A_A:547 no longer at interface
A:543 [GLN] B:1 [A] A:397 [GLN] B:1 [U] ❌ 5I4A_A:397 no longer at interface
A:543 [GLN] B:2 [A] A:397 [GLN] B:2 [A] ❌ 5I4A_A:397 no longer at interface
A:220 [THR] B:8 [A] A:150 [THR] B:8 [C] ❌ 5I4A_A:150 no longer at interface
A:788 [TYR] B:3 [A] A:606 [ALA] B:3 [U] ❌ 5I4A_A:606 no longer at interface
A:788 [TYR] B:4 [A] A:606 [ALA] B:4 [A] ❌ 5I4A_A:606 no longer at interface
A:219 [ALA] B:8 [A] A:149 [PHE] B:8 [C] ❌ 5I4A_A:149 no longer at interface
A:542 [THR] B:1 [A] A:396 [LEU] B:1 [U] ❌ 5I4A_A:396 no longer at interface
A:349 [ARG] B:8 [A] A:206 [PHE] B:8 [C] ❌ 5I4A_A:206 no longer at interface
A:568 [LYS] B:1 [A] A:422 [PHE] B:1 [U] ❌ 5I4A_A:422 no longer at interface
A:217 [VAL] B:8 [A] A:147 [PRO] B:8 [C] ❌ 5I4A_A:147 no longer at interface
A:531 [LYS] B:1 [A] A:387 [VAL] B:1 [U] ❌ 5I4A_A:387 no longer at interface
A:712 [ARG] B:8 [A] A:549 [ASN] B:8 [C] ❌ 5I4A_A:549 no longer at interface
A:759 [ARG] B:8 [A] A:577 [LYS] B:8 [C] ❌ 5I4A_A:577 no longer at interface
A:175 [VAL] B:8 [A] A:104 [LYS] B:8 [C] ❌ 4KXT_A:175 no longer at interface
A:176 [GLY] B:8 [A] A:106 [GLY] B:8 [C] ❌ 4KXT_A:176 no longer at interface
A:201 [HIS] B:8 [A] A:131 [LYS] B:8 [C] ❌ 4KXT_A:201 no longer at interface
A:525 [PRO] B:1 [A] A:381 [GLY] B:1 [U] ❌ 4KXT_A:525 no longer at interface
A:806 [LEU] B:4 [A] A:625 [LYS] B:4 [A] ❌ 4KXT_A:806 no longer at interface
A:850 [THR] B:3 [A] A:635 [LEU] B:3 [U] ❌ 4KXT_A:850 no longer at interface
A:850 [THR] B:1 [A] A:635 [LEU] B:1 [U] ❌ 4KXT_A:850 no longer at interface
A:853 [THR] B:3 [A] A:636 [TYR] B:3 [U] ❌ 4KXT_A:853 no longer at interface
A:853 [THR] B:1 [A] A:636 [TYR] B:1 [U] ❌ 4KXT_A:853 no longer at interface

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Properties of this pair

Common ECOD label(s)
 Common RFAM label(s)
 Interface TM-score
 Interface RMSD
 Percentage identity
 Protein TM-score
 RNA TM-score
 Protein coverage
 RNA coverage
 Percentage conservation
 Apolar conservation
 H-bond conservation
 Percentage switching out
Ribonuclease H-like & Argonaute, N-terminal domain & SH3 0.77 3.27 0.03 0.78 0.16 0.42 0.42 0.68 0.76 0.21 0.71


Other pairs involving 4KXT_A_B or 5I4A_A_B

Total number of entries: 28

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
4F3T_A_R 5I4A_A_B 0.56 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4F3T_A_R 4KXT_A_B 0.98 0.97 1.12 0.33 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 4KXT_A_B 0.96 0.96 1.84 0.55 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KRE_A_R 5I4A_A_B 0.58 0.77 2.76 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 5I4A_A_B 0.59 0.77 2.79 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4KRF_A_R 4KXT_A_B 0.95 0.97 1.54 0.25 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6D92_A_C 0.48 0.71 3.26 0.08 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZS_A_C,D 0.57 0.59 2.56 0.09 Ribonuclease H-like compare
4KXT_A_B 6OZP_B_C,D 0.48 0.61 2.62 0.05 Ribonuclease H-like compare
4KXT_A_B 5JS1_A_B 0.97 0.98 0.84 0.2 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4W5T_A_B,D 0.89 0.91 3.15 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5AWH_A_C 0.50 0.71 3.34 0.13 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6CBD_A_B,C 0.91 0.9 2.96 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZS_B_C,D 0.51 0.61 2.64 0.09 Ribonuclease H-like compare
4KXT_A_B 4W5O_A_B,D 0.87 0.91 3.12 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4Z4D_A_B,D 0.87 0.91 2.97 0.17 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 5I4A_A_B 0.68 0.77 3.27 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 4OLA_A_B 0.98 0.98 0.92 0.9 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6OZP_A_C,D 0.57 0.6 2.58 0.08 Ribonuclease H-like compare
4KXT_A_B 6OON_A_B 0.95 0.95 2.24 0.83 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 compare
4KXT_A_B 6MFN_A_C,E 0.90 0.85 1.72 0.17 Ribonuclease H-like & Argonaute, N-terminal domain compare
4OLA_A_B 5I4A_A_B 0.61 0.77 3.22 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5O_A_B,D 5I4A_A_B 0.39 0.78 2.71 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4W5T_A_B,D 5I4A_A_B 0.51 0.78 2.78 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
4Z4D_A_B,D 5I4A_A_B 0.39 0.78 3.14 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6CBD_A_B,C 0.39 0.78 2.46 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 5JS1_A_B 0.60 0.77 3.53 0.03 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare
5I4A_A_B 6OON_A_B 0.56 0.77 3.58 0.05 Ribonuclease H-like & Argonaute, N-terminal domain & SH3 & Middle domain in Argonaute homologs compare