Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
View
Focus on
InterfaceRNA
Protein
All
Show chains
Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
4ED5_A
|
4ED5_D
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:21 [ASN] | D:10 [U] | 2.75 | base:SC | 83.74 | ||
A:23 [ILE] | D:8 [U] | 3.44 | 61.06 | |||
A:23 [ILE] | D:9 [U] | 3.63 | 61.06 | |||
A:25 [ASN] | D:8 [U] | 3.12 | sugar:SC | base/AA stacks | 68.4 | |
A:26 [TYR] | D:5 [U] | 3.34 | base/AA stacks | 74.16 | ||
A:26 [TYR] | D:7 [A] | 3.61 | 74.16 | |||
A:26 [TYR] | D:8 [U] | 4.55 | 74.16 | |||
A:29 [GLN] | D:6 [U] | 3.34 | 25.29 | |||
A:29 [GLN] | D:7 [A] | 2.59 | base:SC | 25.29 | ||
A:50 [LYS] | D:10 [U] | 3.28 | 44.93 | |||
A:50 [LYS] | D:11 [U] | 4.84 | 44.93 | |||
A:52 [ILE] | D:10 [U] | 3.28 | 49.77 | |||
A:59 [HIS] | D:7 [A] | 3.35 | base:SC | 43.91 | ||
A:60 [SER] | D:7 [A] | 3.48 | 86.21 | |||
A:61 [LEU] | D:7 [A] | 2.52 | sugar:BB | 67.41 | ||
A:62 [GLY] | D:7 [A] | 4.3 | 84.99 | |||
A:63 [TYR] | D:7 [A] | 3.43 | 61.05 | |||
A:63 [TYR] | D:8 [U] | 3.76 | 61.05 | |||
A:63 [TYR] | D:9 [U] | 3.35 | 61.05 | |||
A:65 [PHE] | D:9 [U] | 3.33 | 79.09 | |||
A:65 [PHE] | D:10 [U] | 3.39 | base/AA stacks | 79.09 | ||
A:88 [SER] | D:5 [U] | 4.59 | 56.44 | |||
A:89 [LYS] | D:5 [U] | 2.62 | sugar:SC | 63.52 | ||
A:89 [LYS] | D:6 [U] | 3.28 | 63.52 | |||
A:89 [LYS] | D:7 [A] | 4.37 | 63.52 | |||
A:90 [THR] | D:5 [U] | 2.63 | base:BB, base:BB | 5.58 | ||
A:91 [ILE] | D:5 [U] | 4.85 | 62.2 | |||
A:92 [LYS] | D:5 [U] | 4.82 | 39.34 | |||
A:92 [LYS] | D:8 [U] | 2.95 | base:SC | 39.34 | ||
A:94 [SER] | D:8 [U] | 4.83 | 63.83 | |||
A:95 [TYR] | D:9 [U] | 4.52 | 0.0 | |||
A:96 [ALA] | D:9 [U] | 3.57 | 77.99 | |||
A:96 [ALA] | D:10 [U] | 4.7 | 77.99 | |||
A:97 [ARG] | D:8 [U] | 3.21 | base:SC | 58.03 | ||
A:97 [ARG] | D:9 [U] | 2.78 | base:BB, base:BB | 58.03 | ||
A:98 [PRO] | D:9 [U] | 4.06 | 56.76 | |||
A:99 [SER] | D:9 [U] | 2.74 | sugar:SC | 65.47 | ||
A:99 [SER] | D:10 [U] | 3.78 | 65.47 | |||
A:100 [SER] | D:9 [U] | 3.24 | sugar:BB | 57.69 | ||
A:103 [ILE] | D:8 [U] | 4.86 | 5.82 | |||
A:103 [ILE] | D:9 [U] | 3.64 | 5.82 | |||
A:104 [LYS] | D:9 [U] | 3.61 | 38.03 | |||
A:104 [LYS] | D:10 [U] | 3.05 | 38.03 | |||
A:105 [ASP] | D:9 [U] | 4.35 | 35.5 | |||
A:107 [ASN] | D:4 [U] | 2.69 | base:SC | 77.67 | ||
A:107 [ASN] | D:8 [U] | 4.51 | 77.67 | |||
A:109 [TYR] | D:2 [U] | 3.99 | 60.35 | |||
A:109 [TYR] | D:3 [U] | 3.31 | base/AA stacks | 60.35 | ||
A:133 [ILE] | D:8 [U] | 3.25 | 49.29 | |||
A:134 [ASN] | D:8 [U] | 3.52 | base/AA stacks | 68.86 | ||
A:136 [ARG] | D:4 [U] | 3.6 | 60.55 | |||
A:136 [ARG] | D:5 [U] | 3.23 | 60.55 | |||
A:138 [LEU] | D:3 [U] | 3.75 | 58.56 | |||
A:138 [LEU] | D:4 [U] | 3.52 | 58.56 | |||
A:138 [LEU] | D:5 [U] | 4.21 | 58.56 | |||
A:147 [ARG] | D:2 [U] | 2.7 | 71.37 | |||
A:147 [ARG] | D:3 [U] | 3.16 | 71.37 | |||
A:151 [PHE] | D:3 [U] | 3.33 | 83.12 | |||
A:151 [PHE] | D:4 [U] | 3.28 | base/AA stacks | 83.12 | ||
A:153 [ARG] | D:8 [U] | 3.15 | base/AA stacks | 43.7 | ||
A:153 [ARG] | D:9 [U] | 4.31 | 43.7 | |||
A:182 [LYS] | D:3 [U] | 2.69 | base:SC | 69.37 | ||
A:184 [ALA] | D:3 [U] | 3.89 | 98.56 | |||
A:184 [ALA] | D:4 [U] | 4.68 | 98.56 | |||
A:185 [ALA] | D:3 [U] | 2.99 | base:BB | 80.44 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group141 | 4ED5_A_D | A: Elav-like protein 1, Homo sapiens (genetically engineered) D: N/A | Q15717 | RNA-binding domain, RBD | ✘ |
Interologs
Total number of interologs for this interface: 5
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
4ED5_A_D | 6F4G_B_C | 0.57 | 0.62 | 2.44 | 0.1 | RNA-binding domain, RBD | compare | |
1A9N_B_Q | 4ED5_A_D | 0.54 | 0.62 | 2.45 | 0.1 | RNA-binding domain, RBD | compare | |
4ED5_A_D | 6SQN_A_X | 0.55 | 0.65 | 2.53 | 0.1 | RNA-binding domain, RBD | compare | |
4ED5_A_D | 6F4H_A_B | 0.56 | 0.65 | 2.49 | 0.1 | RNA-binding domain, RBD | compare | |
1G2E_A_B | 4ED5_A_D | 0.92 | 0.95 | 0.7 | 0.8 | RNA-binding domain, RBD | compare |