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All interfaces > All interologs > Interface groups > group141 > 4N0T_A_B

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Licorice
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RNA

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Licorice
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Chain
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Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

4N0T_A
4N0T_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:36 [ARG] B:51 [A] 4.81 87.58
A:36 [ARG] B:52 [G] 2.98 sugar:BB 87.58
A:37 [ASN] B:52 [G] 3.87 83.59
A:38 [ARG] B:50 [G] 2.99 sugar:SC base/AA stacks 98.95
A:38 [ARG] B:52 [G] 2.92 base:SC, base:BB 98.95
A:39 [GLU] B:52 [G] 4.48 98.45
A:118 [THR] B:50 [G] 4.74 98.97
A:120 [TRP] B:48 [C] 3.46 64.55
A:120 [TRP] B:49 [A] 3.0 sugar:SC base/AA stacks 64.55
A:122 [THR] B:47 [A] 3.02 sugar:SC 94.03
A:122 [THR] B:48 [C] 3.33 94.03
A:123 [ASN] B:46 [U] 2.72 base:SC, base:SC 98.97
A:123 [ASN] B:47 [A] 3.27 sugar:BB base/AA stacks 98.97
A:148 [ARG] B:50 [G] 2.87 base:SC, base:SC 98.95
A:149 [LEU] B:51 [A] 4.75 70.86
A:150 [PRO] B:50 [G] 4.11 98.77
A:150 [PRO] B:51 [A] 3.63 98.77
A:151 [SER] B:50 [G] 4.6 98.92
A:151 [SER] B:51 [A] 2.8 98.92
A:151 [SER] B:53 [A] 3.6 98.92
A:153 [ARG] B:51 [A] 4.92 80.43
A:153 [ARG] B:53 [A] 3.87 80.43
A:153 [ARG] B:57 [U] 4.61 80.43
A:153 [ARG] B:58 [C] 2.72 base:SC, base:SC, base:BB 80.43
A:154 [PHE] B:53 [A] 3.76 51.72
A:154 [PHE] B:54 [U] 3.28 base/AA stacks 51.72
A:154 [PHE] B:57 [U] 2.82 base:BB 51.72
A:154 [PHE] B:58 [C] 3.94 51.72
A:155 [ASN] B:48 [C] 4.62 94.31
A:155 [ASN] B:57 [U] 4.99 94.31
A:157 [SER] B:46 [U] 4.92 73.17
A:157 [SER] B:47 [A] 3.52 73.17
A:157 [SER] B:48 [C] 4.09 73.17
A:158 [ARG] B:47 [A] 4.24 98.82
A:158 [ARG] B:48 [C] 3.27 98.82
A:158 [ARG] B:50 [G] 3.17 98.82
A:158 [ARG] B:51 [A] 2.69 98.82
A:158 [ARG] B:53 [A] 3.37 98.82
A:159 [ARG] B:46 [U] 3.15 base:SC 98.95
A:159 [ARG] B:47 [A] 2.83 sugar:BB 98.95
A:159 [ARG] B:48 [C] 2.86 98.95
A:160 [PHE] B:48 [C] 3.38 98.67
A:160 [PHE] B:49 [A] 3.59 98.67
A:160 [PHE] B:50 [G] 3.63 98.67
A:162 [TYR] B:49 [A] 2.81 base:SC 98.09
A:162 [TYR] B:50 [G] 3.23 base/AA stacks 98.09
A:186 [TYR] B:46 [U] 3.33 61.0
A:189 [VAL] B:47 [A] 4.24 76.67
A:191 [LYS] B:49 [A] 3.6 78.13
A:192 [VAL] B:49 [A] 4.49 78.39
A:193 [SER] B:49 [A] 3.39 99.0
A:194 [ASN] B:49 [A] 2.95 base:BB 82.32
A:195 [PRO] B:49 [A] 3.35 92.52
A:195 [PRO] B:50 [G] 3.84 92.52
A:195 [PRO] B:52 [G] 4.19 92.52
A:197 [GLU] B:49 [A] 4.41 15.32
A:198 [LYS] B:49 [A] 3.25 80.27
A:199 [SER] B:48 [C] 4.4 45.3
A:199 [SER] B:49 [A] 4.34 45.3
A:200 [LYS] B:48 [C] 3.9 20.09
A:201 [ARG] B:47 [A] 4.14 98.6
A:201 [ARG] B:48 [C] 3.0 base/AA stacks 98.6
A:201 [ARG] B:49 [A] 2.8 98.6
A:202 [THR] B:45 [A] 3.64 70.04
A:202 [THR] B:47 [A] 3.68 70.04
A:202 [THR] B:48 [C] 3.02 base:BB, base:SC 70.04
A:203 [ASP] B:44 [A] 3.58 83.08
A:203 [ASP] B:47 [A] 4.58 83.08
A:203 [ASP] B:48 [C] 3.74 83.08
A:206 [THR] B:43 [C] 3.78 30.77
A:206 [THR] B:44 [A] 3.13 30.77
A:211 [GLU] B:43 [C] 2.67 base:SC, base:SC 95.55
A:211 [GLU] B:44 [A] 4.32 95.55
A:213 [MET] B:41 [A] 3.92 43.87
A:213 [MET] B:42 [A] 3.49 43.87
A:215 [ARG] B:40 [A] 4.97 B:91 [A] 62.28
A:215 [ARG] B:41 [A] 3.42 62.28
A:215 [ARG] B:42 [A] 4.01 62.28
A:215 [ARG] B:91 [A] 3.45 B:40 [A] base/AA stacks 62.28
A:216 [ASN] B:39 [G] 4.21 B:92 [C] 83.62
A:216 [ASN] B:40 [A] 3.06 B:91 [A] base:SC 83.62
A:216 [ASN] B:91 [A] 3.69 B:40 [A] 83.62
A:216 [ASN] B:92 [C] 2.88 B:39 [G] base:SC 83.62
A:239 [LYS] B:44 [A] 2.79 sugar:SC 39.8
A:239 [LYS] B:45 [A] 4.21 39.8
A:241 [ASN] B:43 [C] 2.99 base:SC 56.46
A:241 [ASN] B:44 [A] 3.52 56.46
A:242 [ILE] B:43 [C] 4.09 72.9
A:243 [PRO] B:41 [A] 3.52 78.52
A:243 [PRO] B:42 [A] 3.99 78.52
A:243 [PRO] B:43 [C] 3.63 78.52
A:244 [ALA] B:41 [A] 4.49 48.54
A:246 [GLN] B:41 [A] 3.26 24.42
A:250 [SER] B:40 [A] 4.53 B:91 [A] 44.36
A:251 [PHE] B:40 [A] 3.19 B:91 [A] 48.25
A:251 [PHE] B:41 [A] 3.19 48.25
A:252 [ASN] B:39 [G] 3.08 B:92 [C] sugar:SC 71.76
A:252 [ASN] B:40 [A] 2.84 B:91 [A] 71.76
A:253 [ASN] B:39 [G] 3.31 B:92 [C] base:SC 61.09
A:253 [ASN] B:40 [A] 2.84 B:91 [A] base:SC 61.09
A:253 [ASN] B:41 [A] 3.31 61.09
A:254 [CYS] B:41 [A] 3.89 87.76
A:255 [CYS] B:41 [A] 3.72 47.76
A:255 [CYS] B:42 [A] 4.54 47.76
A:257 [PHE] B:42 [A] 3.41 89.09
A:257 [PHE] B:43 [C] 3.27 base/AA stacks 89.09
A:273 [ASN] B:91 [A] 3.95 B:40 [A] sugar:SC 79.56
A:274 [ARG] B:91 [A] 4.28 B:40 [A] 43.29
A:274 [ARG] B:92 [C] 3.71 B:39 [G] 43.29
A:281 [GLU] B:92 [C] 4.18 B:39 [G] 17.14
A:283 [SER] B:91 [A] 2.83 B:40 [A] base:SC 30.52
A:283 [SER] B:92 [C] 3.99 B:39 [G] 30.52
A:287 [ALA] B:42 [A] 3.86 89.57
A:287 [ALA] B:43 [C] 4.49 89.57
A:287 [ALA] B:55 [G] 4.92 89.57
A:288 [ASP] B:42 [A] 2.95 base:SC, base:BB 53.59
A:288 [ASP] B:43 [C] 4.7 53.59
A:288 [ASP] B:55 [G] 2.86 base:SC 53.59
A:289 [LYS] B:55 [G] 2.78 base:BB 37.67
A:290 [LYS] B:42 [A] 2.79 sugar:SC 66.73
A:290 [LYS] B:43 [C] 2.58 66.73
A:290 [LYS] B:44 [A] 3.3 66.73
A:291 [PRO] B:57 [U] 3.36 59.45
A:292 [PHE] B:55 [G] 3.36 base/AA stacks 47.99
A:292 [PHE] B:57 [U] 3.32 47.99
A:293 [LEU] B:42 [A] 3.75 73.18
A:295 [ARG] B:57 [U] 3.26 68.58
A:295 [ARG] B:58 [C] 2.88 base/AA stacks 68.58
A:296 [ASN] B:57 [U] 3.36 60.65
A:299 [LYS] B:56 [A] 4.44 53.7
A:299 [LYS] B:57 [U] 4.08 53.7
A:299 [LYS] B:58 [C] 2.88 53.7
A:300 [ARG] B:37 [U] 3.76 B:94 [A] 48.56
A:321 [ASP] B:51 [A] 2.87 base:SC 97.24
A:322 [LYS] B:51 [A] 4.57 91.59
A:350 [SER] B:58 [C] 3.48 base:SC 80.51
A:351 [ASP] B:58 [C] 3.55 base/AA stacks 78.77
A:394 [TYR] B:83 [A] 4.2 B:64 [U] 69.57
A:395 [ASN] B:82 [A] 4.45 B:65 [U] 69.57
A:395 [ASN] B:83 [A] 3.35 B:64 [U] 69.57
A:395 [ASN] B:84 [C] 4.78 B:63 [G] 69.57
A:398 [GLN] B:82 [A] 4.19 B:65 [U] 69.57
A:398 [GLN] B:83 [A] 4.92 B:64 [U] 69.57

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group141 4N0T_A_B A: U4/u6 snRNA-associated-splicing factor prp24, Saccharomyces cerevisiae (genetically engineered) B: U6 snRNA P49960 RNA-binding domain, RBD U6 spliceosomal RNA ✘

Interologs

Total number of interologs for this interface: 5

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
1URN_A_P 4N0T_A_B 0.55 0.62 3.78 0.0 RNA-binding domain, RBD compare
4N0T_A_B 6SQN_A_X 0.59 0.65 3.87 0.0 RNA-binding domain, RBD compare
4N0T_A_B 6F4G_B_C 0.58 0.61 3.62 0.0 RNA-binding domain, RBD compare
4N0T_A_B 6F4H_A_B 0.56 0.64 3.75 0.0 RNA-binding domain, RBD compare
4N0T_A_B 5TF6_A_B 0.98 0.95 0.87 0.96 RNA-binding domain, RBD U6 spliceosomal RNA compare