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All interfaces > All interologs > Interface groups > group141 > 6F4G_B_C

Interface analysis

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Licorice
Surface

RNA

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Licorice
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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

6F4G_B
6F4G_C
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
B:8 [THR] C:14 [A] 4.4 92.2
B:10 [TYR] C:12 [G] 3.41 83.93
B:10 [TYR] C:13 [C] 3.29 base/AA stacks 83.93
B:12 [ASN] C:11 [U] 4.39 59.85
B:12 [ASN] C:12 [G] 2.7 base:SC 59.85
B:13 [ASN] C:11 [U] 2.76 base:SC 98.82
B:13 [ASN] C:12 [G] 3.05 base:BB 98.82
B:14 [LEU] C:12 [G] 4.26 85.14
B:16 [GLU] C:9 [A] 3.93 52.52
B:16 [GLU] C:10 [U] 2.76 base:SC 52.52
B:16 [GLU] C:12 [G] 2.75 base:SC, base:SC 52.52
B:17 [LYS] C:7 [G] 3.1 C:21 [C] base:SC 50.12
B:17 [LYS] C:8 [U] 3.46 C:20 [G] base:SC 50.12
B:17 [LYS] C:9 [A] 4.26 50.12
B:17 [LYS] C:20 [G] 2.88 C:8 [U] base:SC 50.12
B:17 [LYS] C:21 [C] 3.51 C:7 [G] 50.12
B:20 [LYS] C:16 [U] 2.74 base:SC 25.87
B:20 [LYS] C:18 [C] 2.91 25.87
B:20 [LYS] C:19 [C] 2.85 25.87
B:24 [LYS] C:16 [U] 2.77 base:SC 63.68
B:40 [ILE] C:16 [U] 3.44 77.87
B:41 [VAL] C:14 [A] 3.75 34.53
B:41 [VAL] C:15 [G] 3.4 34.53
B:41 [VAL] C:16 [U] 3.3 34.53
B:42 [ALA] C:16 [U] 2.87 base:BB, base:BB 51.81
B:43 [LEU] C:14 [A] 3.73 39.68
B:43 [LEU] C:15 [G] 4.08 39.68
B:43 [LEU] C:16 [U] 3.56 39.68
B:44 [LYS] C:19 [C] 2.54 sugar:BB 49.55
B:44 [LYS] C:20 [G] 4.18 C:8 [U] 49.55
B:45 [THR] C:19 [C] 3.88 67.83
B:46 [LEU] C:10 [U] 3.85 44.57
B:46 [LEU] C:12 [G] 4.2 44.57
B:47 [LYS] C:12 [G] 2.72 sugar:BB 63.03
B:47 [LYS] C:13 [C] 4.69 63.03
B:47 [LYS] C:14 [A] 2.96 63.03
B:48 [MET] C:12 [G] 4.43 69.17
B:48 [MET] C:13 [C] 3.83 69.17
B:48 [MET] C:14 [A] 3.32 69.17
B:49 [ARG] C:10 [U] 3.63 81.07
B:49 [ARG] C:12 [G] 3.24 81.07
B:49 [ARG] C:19 [C] 3.48 sugar:SC 81.07
B:49 [ARG] C:20 [G] 2.76 C:8 [U] 81.07
B:50 [GLY] C:12 [G] 3.41 96.93
B:51 [GLN] C:12 [G] 3.17 base/AA stacks 96.78
B:51 [GLN] C:13 [C] 3.55 96.78
B:53 [PHE] C:13 [C] 3.34 88.17
B:53 [PHE] C:14 [A] 3.34 base/AA stacks 88.17
B:55 [ILE] C:14 [A] 4.55 75.19
B:77 [LYS] C:11 [U] 2.67 base:SC 69.59
B:80 [GLN] C:11 [U] 3.92 43.25
B:82 [ALA] C:13 [C] 3.74 14.52
B:83 [TYR] C:13 [C] 3.05 base:BB 40.55
B:84 [SER] C:13 [C] 3.36 85.45
B:84 [SER] C:14 [A] 3.96 85.45
B:85 [LYS] C:13 [C] 2.97 base:BB 65.31
B:86 [SER] C:13 [C] 4.34 54.63
B:86 [SER] C:14 [A] 3.12 base:SC, base:BB, base:SC 54.63
B:86 [SER] C:15 [G] 4.78 54.63
B:87 [ASP] C:14 [A] 3.59 7.72
B:87 [ASP] C:15 [G] 3.49 7.72
B:88 [SER] C:14 [A] 2.67 base:SC 88.93
B:88 [SER] C:15 [G] 3.26 88.93
B:89 [ASP] C:14 [A] 4.99 54.77
B:89 [ASP] C:15 [G] 2.97 base:BB base/AA stacks 54.77
B:90 [ILE] C:15 [G] 4.97 17.13

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
UniProt ID
ECOD label(s)
RFAM label(s)
Is ribosome? RCSB PDB link
group141 6F4G_B_C B: U1 small nuclear ribonucleoprotein a, Drosophila melanogaster (genetically engineered) C: U2-sl4, Drosophila melanogaster (synthetic) P43332 RNA-binding domain, RBD

Interologs

Total number of interologs for this interface: 20

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
1G2E_A_B 6F4G_B_C 0.57 0.61 3.03 0.15 RNA-binding domain, RBD compare
5TF6_A_B 6F4G_B_C 0.58 0.61 3.75 0.0 RNA-binding domain, RBD compare
6DCL_A_D 6F4G_B_C 0.32 0.61 2.78 0.26 RNA-binding domain, RBD compare
4N0T_A_B 6F4G_B_C 0.58 0.61 3.62 0.0 RNA-binding domain, RBD compare
6F4G_B_C 7DCO_X_G 0.33 0.62 3.54 0.12 RNA-binding domain, RBD compare
4ED5_A_D 6F4G_B_C 0.57 0.62 2.44 0.1 RNA-binding domain, RBD compare
6F4G_B_C 7DCO_p_H 0.23 0.65 0.62 0.14 RNA-binding domain, RBD compare
6F4G_B_C 7DCO_R_G 0.76 0.68 2.57 0.14 compare
3MXH_P_R 6F4G_B_C 0.80 0.77 0.94 0.46 RNA-binding domain, RBD compare
2NZ4_A_P 6F4G_B_C 0.85 0.8 0.45 0.43 RNA-binding domain, RBD compare
1M5O_C_B 6F4G_B_C 0.81 0.81 0.4 0.5 RNA-binding domain, RBD compare
4PKD_B_V 6F4G_B_C 0.81 0.81 0.46 0.5 RNA-binding domain, RBD compare
5DDP_D_A 6F4G_B_C 0.82 0.81 0.36 0.46 RNA-binding domain, RBD compare
1DRZ_A_B 6F4G_B_C 0.80 0.83 0.38 0.43 RNA-binding domain, RBD compare
4PR6_A_B 6F4G_B_C 0.80 0.83 0.4 0.46 RNA-binding domain, RBD compare
1SJ3_P_R 6F4G_B_C 0.83 0.83 0.4 0.55 RNA-binding domain, RBD compare
1URN_A_P 6F4G_B_C 0.78 0.85 0.36 0.58 RNA-binding domain, RBD compare
6F4G_B_C 6F4H_A_B 0.81 0.87 0.36 0.5 RNA-binding domain, RBD compare
6F4G_B_C 6SQN_A_X 0.91 0.87 0.39 0.6 RNA-binding domain, RBD compare
1A9N_B_Q 6F4G_B_C 0.94 0.92 0.25 0.79 RNA-binding domain, RBD compare