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All interfaces > All interologs > Interface groups > group141 > 6F4H_A_B

Interface analysis

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Licorice
Surface

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Licorice
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Chain
Chain (with hetatm)
Chainbow
Hydrophobicity
Electrostatics (surface only)
Conservation*

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Rim - Core

Contacts -

6F4H_A
6F4H_B
Distance
Base Pair
Hbond nuc:res
Base Stacking
Residue conservation
A:3 [MET] B:11 [C] 3.63 9.55
A:8 [THR] B:12 [A] 4.51 89.77
A:10 [TYR] B:10 [G] 3.4 78.88
A:10 [TYR] B:11 [C] 3.36 base/AA stacks 78.88
A:12 [ASN] B:9 [U] 3.97 62.12
A:12 [ASN] B:10 [G] 2.94 base:SC 62.12
A:13 [ASN] B:9 [U] 2.83 base:SC 98.8
A:13 [ASN] B:10 [G] 3.03 base:BB 98.8
A:14 [LEU] B:10 [G] 4.29 82.99
A:16 [GLU] B:7 [A] 4.35 49.97
A:16 [GLU] B:8 [U] 2.75 base:SC 49.97
A:16 [GLU] B:10 [G] 2.76 base:SC 49.97
A:19 [LYS] B:2 [G] 4.88 B:21 [C] 55.14
A:41 [VAL] B:12 [A] 4.34 22.62
A:43 [LEU] B:12 [A] 3.22 1.64
A:43 [LEU] B:15 [U] 4.85 1.64
A:43 [LEU] B:16 [C] 4.85 1.64
A:44 [LYS] B:17 [G] 4.86 B:6 [C] 40.3
A:45 [THR] B:16 [C] 3.35 64.55
A:45 [THR] B:17 [G] 3.47 B:6 [C] 64.55
A:46 [LEU] B:7 [A] 3.8 20.54
A:46 [LEU] B:8 [U] 4.25 20.54
A:46 [LEU] B:10 [G] 4.83 20.54
A:46 [LEU] B:17 [G] 2.91 B:6 [C] 20.54
A:47 [LYS] B:10 [G] 2.61 sugar:BB 56.45
A:47 [LYS] B:11 [C] 4.52 56.45
A:47 [LYS] B:12 [A] 2.98 56.45
A:48 [MET] B:10 [G] 4.55 65.78
A:48 [MET] B:11 [C] 3.79 65.78
A:48 [MET] B:12 [A] 3.35 65.78
A:49 [ARG] B:7 [A] 2.72 base:SC 80.77
A:49 [ARG] B:8 [U] 3.42 80.77
A:49 [ARG] B:10 [G] 3.16 80.77
A:49 [ARG] B:17 [G] 3.0 B:6 [C] base:SC, base:SC 80.77
A:50 [GLY] B:10 [G] 3.46 95.52
A:51 [GLN] B:10 [G] 3.14 base/AA stacks 89.74
A:51 [GLN] B:11 [C] 3.58 89.74
A:53 [PHE] B:11 [C] 3.52 83.9
A:53 [PHE] B:12 [A] 3.35 base/AA stacks 83.9
A:55 [ILE] B:12 [A] 4.68 67.34
A:77 [LYS] B:9 [U] 3.14 base:SC 70.05
A:80 [GLN] B:9 [U] 4.91 11.66
A:82 [ALA] B:11 [C] 3.87 40.48
A:83 [TYR] B:11 [C] 2.83 base:BB 40.54
A:84 [SER] B:11 [C] 3.42 84.48
A:84 [SER] B:12 [A] 3.88 84.48
A:85 [LYS] B:11 [C] 3.08 base:BB, sugar:SC 55.44
A:86 [SER] B:11 [C] 4.68 27.4
A:86 [SER] B:12 [A] 2.97 base:BB 27.4
A:86 [SER] B:13 [C] 4.71 27.4
A:87 [ASP] B:12 [A] 3.72 15.51
A:87 [ASP] B:13 [C] 2.9 base:BB 15.51
A:88 [SER] B:12 [A] 2.69 base:SC, base:SC 95.64
A:88 [SER] B:13 [C] 3.52 95.64
A:89 [ASP] B:12 [A] 4.91 62.6
A:89 [ASP] B:13 [C] 2.97 base:BB base/AA stacks 62.6
A:89 [ASP] B:14 [C] 4.59 62.6
A:90 [ILE] B:13 [C] 4.72 21.91

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*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)

Properties of this interface

Interolog group ID Structure ID Structure description
 UniProt ID
 		ECOD label(s)
 		RFAM label(s)
 		Is ribosome? RCSB PDB link
group141 6F4H_A_B A: U1 small nuclear ribonucleoprotein a, Drosophila melanogaster (genetically engineered) B: U1-sl2, Drosophila melanogaster (synthetic) P43332 RNA-binding domain, RBD ✘

Interologs

Total number of interologs for this interface: 20

Interface 1 Interface 2 Percentage conservation
 		Interface TM-score
 		Interface RMSD
 		Percentage identity
 		Common ECOD label(s)
 		Common RFAM label(s)
 		Explore both interfaces
1DRZ_A_B 6F4H_A_B 0.94 0.95 0.38 0.68 RNA-binding domain, RBD compare
6F4G_B_C 6F4H_A_B 0.81 0.87 0.36 0.5 RNA-binding domain, RBD compare
4ED5_A_D 6F4H_A_B 0.56 0.65 2.49 0.1 RNA-binding domain, RBD compare
1G2E_A_B 6F4H_A_B 0.57 0.64 3.02 0.1 RNA-binding domain, RBD compare
1URN_A_P 6F4H_A_B 0.95 0.94 0.32 0.72 RNA-binding domain, RBD compare
4PR6_A_B 6F4H_A_B 0.94 0.95 0.38 0.68 RNA-binding domain, RBD compare
3MXH_P_R 6F4H_A_B 0.95 0.91 0.91 0.59 RNA-binding domain, RBD compare
1A9N_B_Q 6F4H_A_B 0.81 0.85 0.49 0.5 RNA-binding domain, RBD compare
5TF6_A_B 6F4H_A_B 0.57 0.64 3.83 0.0 RNA-binding domain, RBD compare
1M5O_C_B 6F4H_A_B 0.95 0.95 0.48 0.7 RNA-binding domain, RBD compare
6DCL_A_D 6F4H_A_B 0.33 0.63 1.94 0.17 RNA-binding domain, RBD compare
4N0T_A_B 6F4H_A_B 0.56 0.64 3.75 0.0 RNA-binding domain, RBD compare
4PKD_B_V 6F4H_A_B 0.88 0.94 0.45 0.65 RNA-binding domain, RBD compare
2NZ4_A_P 6F4H_A_B 0.92 0.95 0.41 0.7 RNA-binding domain, RBD compare
1SJ3_P_R 6F4H_A_B 0.97 0.96 0.38 0.71 RNA-binding domain, RBD compare
5DDP_D_A 6F4H_A_B 0.92 0.96 0.33 0.68 RNA-binding domain, RBD compare
6F4H_A_B 7DCO_4_G 0.35 0.61 1.28 0.17 RNA-binding domain, RBD compare
6F4H_A_B 6SQN_A_X 0.93 0.92 0.38 0.74 RNA-binding domain, RBD compare
6F4H_A_B 7DCO_R_G 0.77 0.7 2.58 0.17 compare
6F4H_A_B 7DCO_X_G 0.43 0.65 2.51 0.12 RNA-binding domain, RBD compare