Interface analysis
Style
Protein
CartoonLicorice
Surface
RNA
CartoonLicorice
Surface
Color
ChainChain (with hetatm)
Chainbow
Hydrophobicity Electrostatics (surface only) Conservation*
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InterfaceRNA
Protein
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Interface
show as licoriceshow Accessibility
Rim - Core
Contacts -
6XH2_A
|
6XH2_D
|
Distance
|
Base Pair
|
Hbond nuc:res
|
Base Stacking
|
Residue conservation
|
---|---|---|---|---|---|---|
A:2 [ALA] | D:35 [A] | 3.18 | 32.89 | |||
A:4 [PRO] | D:35 [A] | 3.97 | 20.79 | |||
A:6 [THR] | D:35 [A] | 4.11 | 17.73 | |||
A:13 [TYR] | D:35 [A] | 3.15 | base/AA stacks | 82.61 | ||
A:15 [ASN] | D:35 [A] | 3.37 | 54.23 | |||
A:19 [SER] | D:24 [C] | 4.48 | 39.02 | |||
A:20 [LYS] | D:24 [C] | 3.31 | 61.18 | |||
A:22 [LYS] | D:25 [U] | 3.08 | base:SC | 42.43 | ||
A:23 [LYS] | D:22 [A] | 3.17 | D:40 [U] | 43.17 | ||
A:23 [LYS] | D:23 [U] | 4.77 | 43.17 | |||
A:47 [ARG] | D:22 [A] | 3.35 | D:40 [U] | base/AA stacks | 50.31 | |
A:47 [ARG] | D:23 [U] | 2.78 | sugar:SC | base/AA stacks | 50.31 | |
A:47 [ARG] | D:26 [G] | 2.82 | D:39 [C] | base:SC, base:SC | 50.31 | |
A:47 [ARG] | D:39 [C] | 4.65 | D:26 [G] | 50.31 | ||
A:48 [THR] | D:23 [U] | 3.34 | 72.09 | |||
A:48 [THR] | D:36 [G] | 4.53 | D:29 [C] | 72.09 | ||
A:49 [ARG] | D:23 [U] | 3.4 | base/AA stacks | 36.59 | ||
A:49 [ARG] | D:27 [A] | 3.31 | D:38 [U] | base/AA stacks | 36.59 | |
A:49 [ARG] | D:28 [G] | 2.86 | D:37 [C] | base:SC | 36.59 | |
A:49 [ARG] | D:29 [C] | 3.62 | D:36 [G] | 36.59 | ||
A:49 [ARG] | D:36 [G] | 4.11 | D:29 [C] | 36.59 | ||
A:49 [ARG] | D:37 [C] | 3.8 | D:28 [G] | 36.59 | ||
A:50 [THR] | D:34 [G] | 4.52 | D:30 [C] | 41.33 | ||
A:51 [PRO] | D:24 [C] | 3.48 | 47.46 | |||
A:52 [ARG] | D:29 [C] | 4.62 | D:36 [G] | 85.42 | ||
A:52 [ARG] | D:34 [G] | 3.39 | D:30 [C] | base/AA stacks | 85.42 | |
A:52 [ARG] | D:36 [G] | 2.95 | D:29 [C] | base:SC, base:SC | 85.42 | |
A:54 [GLN] | D:34 [G] | 2.69 | D:30 [C] | sugar:SC | 90.68 | |
A:54 [GLN] | D:35 [A] | 3.3 | 90.68 | |||
A:54 [GLN] | D:36 [G] | 4.39 | D:29 [C] | 90.68 | ||
A:56 [PHE] | D:35 [A] | 3.69 | 82.28 | |||
A:85 [GLN] | D:35 [A] | 3.04 | base:SC | 46.95 | ||
A:86 [TYR] | D:35 [A] | 3.04 | base:BB | 57.18 | ||
A:87 [ALA] | D:35 [A] | 3.41 | 93.22 | |||
A:88 [LYS] | D:35 [A] | 2.79 | base:BB | 64.89 | ||
A:89 [THR] | D:35 [A] | 4.96 | 29.64 |
*Conservation was calculated using Rate4Site
NB: conservation is missing (completly white) for a very small minority of cases in which no homologous sequences were found (e.g. synthetic proteins 7D3J_A & 7EU9_A)
Properties of this interface
Interolog group ID | Structure ID |
Structure description |
UniProt ID |
ECOD label(s) |
RFAM label(s) |
Is ribosome? | RCSB PDB link |
---|---|---|---|---|---|---|---|
group141 | 6XH2_A_D | A: Tar-binding protein 6.6, Homo sapiens (genetically engineered) D: Trans-activation response element, Human immunodeficiency virus 1 (synthetic) | P09012 | RNA-binding domain, RBD | ✘ |
Interologs
Total number of interologs for this interface: 4
Interface 1 | Interface 2 |
Percentage conservation |
Interface TM-score |
Interface RMSD |
Percentage identity |
Common ECOD label(s) |
Common RFAM label(s) |
Explore both interfaces |
---|---|---|---|---|---|---|---|---|
6CMN_A_D | 6XH2_A_D | 0.99 | 0.99 | 0.17 | 0.95 | RNA-binding domain, RBD | compare | |
6DCL_A_D | 6XH2_A_D | 0.48 | 0.6 | 1.96 | 0.14 | RNA-binding domain, RBD | compare | |
6XH2_A_D | 7DCO_X_G | 0.57 | 0.61 | 1.84 | 0.0 | RNA-binding domain, RBD | compare | |
6XH2_A_D | 6XH3_A_D | 0.81 | 0.98 | 1.26 | 0.89 | RNA-binding domain, RBD | compare |