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All interfaces > All interologs > Interface groups > group141 > 3MXH_P_R vs 6F4H_A_B

Interface analysis


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Common contacts -

3MXH_P
3MXH_R
6F4H_A
6F4H_B
Conserved?
P:19 [GLU] R:660 [A] A:16 [GLU] B:7 [A]
P:19 [GLU] R:661 [U] A:16 [GLU] B:8 [U]
P:19 [GLU] R:663 [G] A:16 [GLU] B:10 [G]
P:13 [TYR] R:663 [G] A:10 [TYR] B:10 [G]
P:13 [TYR] R:664 [C] A:10 [TYR] B:11 [C]
P:91 [SER] R:666 [C] A:89 [ASP] B:13 [C]
P:15 [ASN] R:662 [U] A:12 [ASN] B:9 [U]
P:15 [ASN] R:663 [G] A:12 [ASN] B:10 [G]
P:90 [ASP] R:665 [A] A:88 [SER] B:12 [A]
P:90 [ASP] R:666 [C] A:88 [SER] B:13 [C]
P:87 [ALA] R:664 [C] A:84 [SER] B:11 [C]
P:87 [ALA] R:665 [A] A:84 [SER] B:12 [A]
P:17 [LEU] R:663 [G] A:14 [LEU] B:10 [G]
P:11 [THR] R:665 [A] A:8 [THR] B:12 [A]
P:88 [LYS] R:664 [C] A:86 [SER] B:11 [C]
P:88 [LYS] R:665 [A] A:86 [SER] B:12 [A]
P:49 [LEU] R:75 [G] A:46 [LEU] B:17 [G]
P:49 [LEU] R:660 [A] A:46 [LEU] B:7 [A]
P:49 [LEU] R:661 [U] A:46 [LEU] B:8 [U]
P:49 [LEU] R:663 [G] A:46 [LEU] B:10 [G]
P:22 [LYS] R:61 [A] A:19 [LYS] B:2 [G]
P:53 [GLY] R:663 [G] A:50 [GLY] B:10 [G]
P:54 [GLN] R:663 [G] A:51 [GLN] B:10 [G]
P:54 [GLN] R:664 [C] A:51 [GLN] B:11 [C]
P:48 [SER] R:75 [G] A:45 [THR] B:17 [G]
P:48 [SER] R:669 [C] A:45 [THR] B:16 [C]
P:51 [MET] R:663 [G] A:48 [MET] B:10 [G]
P:51 [MET] R:664 [C] A:48 [MET] B:11 [C]
P:51 [MET] R:665 [A] A:48 [MET] B:12 [A]
P:86 [TYR] R:664 [C] A:83 [TYR] B:11 [C]
P:85 [GLN] R:664 [C] A:82 [ALA] B:11 [C]
P:80 [LYS] R:662 [U] A:77 [LYS] B:9 [U]
P:16 [ASN] R:662 [U] A:13 [ASN] B:9 [U]
P:16 [ASN] R:663 [G] A:13 [ASN] B:10 [G]
P:44 [LEU] R:665 [A] A:41 [VAL] B:12 [A]
P:56 [PHE] R:664 [C] A:53 [PHE] B:11 [C]
P:56 [PHE] R:665 [A] A:53 [PHE] B:12 [A]
P:92 [ASP] R:666 [C] A:90 [ILE] B:13 [C]
P:52 [ARG] R:75 [G] A:49 [ARG] B:17 [G]
P:52 [ARG] R:660 [A] A:49 [ARG] B:7 [A]
P:52 [ARG] R:661 [U] A:49 [ARG] B:8 [U]
P:52 [ARG] R:663 [G] A:49 [ARG] B:10 [G]
P:89 [THR] R:665 [A] A:87 [ASP] B:12 [A]
P:89 [THR] R:666 [C] A:87 [ASP] B:13 [C]
P:50 [LYS] R:663 [G] A:47 [LYS] B:10 [G]
P:50 [LYS] R:664 [C] A:47 [LYS] B:11 [C]
P:50 [LYS] R:665 [A] A:47 [LYS] B:12 [A]
P:19 [GLU] R:662 [U] A:16 [GLU] B:9 [U] ❌ 6F4H_A_B
P:44 [LEU] R:666 [C] A:41 [VAL] B:13 [C] ❌ 6F4H_A_B
P:50 [LYS] R:669 [C] A:47 [LYS] B:16 [C] ❌ 6F4H_A_B
P:47 [ARG] R:75 [G] A:44 [LYS] B:17 [G] ❌ 3MXH_P_R
P:88 [LYS] R:666 [C] A:86 [SER] B:13 [C] ❌ 3MXH_P_R
P:91 [SER] R:665 [A] A:89 [ASP] B:12 [A] ❌ 3MXH_P_R
P:22 [LYS] R:62 [A] A:19 [LYS] B:3 [C] ❌ 6F4H_B:3 no longer at interface
P:20 [LYS] R:62 [A] A:17 [LYS] B:3 [C] ❌ 6F4H_A:17, 6F4H_B:3 no longer at interface
P:20 [LYS] R:63 [A] A:17 [LYS] B:4 [C] ❌ 6F4H_A:17, 6F4H_B:4 no longer at interface
P:20 [LYS] R:64 [C] A:17 [LYS] B:5 [G] ❌ 6F4H_A:17, 6F4H_B:5 no longer at interface
P:47 [ARG] R:62 [A] A:44 [LYS] B:3 [C] ❌ 6F4H_B:3 no longer at interface
P:46 [SER] R:668 [C] A:43 [LEU] B:15 [U] ❌ 3MXH_P:46, 3MXH_R:668 no longer at interface
P:91 [SER] R:667 [U] A:89 [ASP] B:14 [C] ❌ 3MXH_R:667 no longer at interface
P:46 [SER] R:669 [C] A:43 [LEU] B:16 [C] ❌ 3MXH_P:46 no longer at interface
P:46 [SER] R:665 [A] A:43 [LEU] B:12 [A] ❌ 3MXH_P:46 no longer at interface
P:58 [ILE] R:665 [A] A:55 [ILE] B:12 [A] ❌ 3MXH_P:58 no longer at interface
P:83 [ARG] R:662 [U] A:80 [GLN] B:9 [U] ❌ 3MXH_P:83 no longer at interface

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Properties of this pair

Common ECOD label(s)
Common RFAM label(s)
Interface TM-score
Interface RMSD
Percentage identity
Protein TM-score
RNA TM-score
Protein coverage
RNA coverage
Percentage conservation
Apolar conservation
H-bond conservation
Percentage switching out
RNA-binding domain, RBD 0.91 0.91 0.59 0.97 0.37 0.96 0.83 0.95 0.88 0.70 0.65


Other pairs involving 3MXH_P_R or 6F4H_A_B

Total number of entries: 31

Interface 1 Interface 2 Percentage conservation
Interface TM-score
Interface RMSD
Percentage identity
Common ECOD label(s)
Common RFAM label(s)
Explore both interfaces
1DRZ_A_B 6F4H_A_B 0.94 0.95 0.38 0.68 RNA-binding domain, RBD compare
1DRZ_A_B 3MXH_P_R 0.92 0.65 0.96 0.78 RNA-binding domain, RBD compare
6F4G_B_C 6F4H_A_B 0.81 0.87 0.36 0.5 RNA-binding domain, RBD compare
4ED5_A_D 6F4H_A_B 0.56 0.65 2.49 0.1 RNA-binding domain, RBD compare
1G2E_A_B 6F4H_A_B 0.57 0.64 3.02 0.1 RNA-binding domain, RBD compare
1URN_A_P 6F4H_A_B 0.95 0.94 0.32 0.72 RNA-binding domain, RBD compare
1URN_A_P 3MXH_P_R 0.97 0.87 0.95 0.78 RNA-binding domain, RBD compare
4PR6_A_B 6F4H_A_B 0.94 0.95 0.38 0.68 RNA-binding domain, RBD compare
3MXH_P_R 6F4H_A_B 0.95 0.91 0.91 0.59 RNA-binding domain, RBD compare
3MXH_P_R 5DDP_D_A 0.95 0.68 0.89 0.69 RNA-binding domain, RBD compare
3MXH_P_R 6SQN_A_X 0.91 0.88 0.96 0.7 RNA-binding domain, RBD compare
3MXH_P_R 4PR6_A_B 0.93 0.65 0.96 0.78 RNA-binding domain, RBD compare
3MXH_P_R 6F4G_B_C 0.80 0.77 0.94 0.46 RNA-binding domain, RBD compare
3MXH_P_R 4PKD_B_V 0.84 0.6 0.68 0.69 RNA-binding domain, RBD compare
1A9N_B_Q 6F4H_A_B 0.81 0.85 0.49 0.5 RNA-binding domain, RBD compare
1A9N_B_Q 3MXH_P_R 0.79 0.78 1.0 0.46 RNA-binding domain, RBD compare
5TF6_A_B 6F4H_A_B 0.57 0.64 3.83 0.0 RNA-binding domain, RBD compare
1M5O_C_B 6F4H_A_B 0.95 0.95 0.48 0.7 RNA-binding domain, RBD compare
1M5O_C_B 3MXH_P_R 0.94 0.68 1.06 0.81 RNA-binding domain, RBD compare
6DCL_A_D 6F4H_A_B 0.33 0.63 1.94 0.17 RNA-binding domain, RBD compare
4N0T_A_B 6F4H_A_B 0.56 0.64 3.75 0.0 RNA-binding domain, RBD compare
4PKD_B_V 6F4H_A_B 0.88 0.94 0.45 0.65 RNA-binding domain, RBD compare
2NZ4_A_P 3MXH_P_R 0.94 0.6 0.92 0.81 RNA-binding domain, RBD compare
2NZ4_A_P 6F4H_A_B 0.92 0.95 0.41 0.7 RNA-binding domain, RBD compare
1SJ3_P_R 6F4H_A_B 0.97 0.96 0.38 0.71 RNA-binding domain, RBD compare
1SJ3_P_R 3MXH_P_R 0.95 0.64 1.0 0.78 RNA-binding domain, RBD compare
5DDP_D_A 6F4H_A_B 0.92 0.96 0.33 0.68 RNA-binding domain, RBD compare
6F4H_A_B 7DCO_4_G 0.35 0.61 1.28 0.17 RNA-binding domain, RBD compare
6F4H_A_B 6SQN_A_X 0.93 0.92 0.38 0.74 RNA-binding domain, RBD compare
6F4H_A_B 7DCO_R_G 0.77 0.7 2.58 0.17 compare
6F4H_A_B 7DCO_X_G 0.43 0.65 2.51 0.12 RNA-binding domain, RBD compare